公开(公告)号：US07504335B2

公开(公告)日：2009-03-17

申请号：US11404058

申请日：2006-04-13

申请人： Michael Yang ,  Aron Rosenfeld ,  Hooman Hafezi ,  Zhi-Wen Sun ,  John Dukovic

发明人： Michael Yang ,  Aron Rosenfeld ,  Hooman Hafezi ,  Zhi-Wen Sun ,  John Dukovic

IPC分类号： H01L21/44

CPC分类号： H01L23/53238 ,  H01L21/76855 ,  H01L21/76873 ,  H01L2924/0002 ,  H01L2924/00

摘要： Generally, the process includes depositing a barrier layer and seed layer on a feature formed in a dielectric layer, performing a grafting process, initiating a copper layer and then filing the feature by use of a bulk copper fill process. Copper features formed according to aspects described herein have desirable adhesion properties to a barrier and seed layers formed on a semiconductor substrate and demonstrate enhanced electromigration and stress migration results in the fabricated devices formed on the substrate.

摘要翻译： 通常，该方法包括在形成在电介质层中的特征上沉积阻挡层和种子层，执行接枝过程，引发铜层，然后通过使用大量铜填充工艺来填充该特征。 根据本文描述的方面形成的铜特征对于形成在半导体衬底上的阻挡层和种子层具有期望的粘附性能，并且证明增强的电迁移和应力迁移导致形成在衬底上的制造器件。

公开(公告)号：US07433739B1

公开(公告)日：2008-10-07

申请号：US11001374

申请日：2004-11-30

申请人： Scott Salys ,  Chris Parrillo ,  Matt Phillips ,  Luz Padilla ,  Jnyan Patel ,  Kevin L. Morgan ,  Michael Yang ,  Sheldon Williams ,  Andrew W. McGarvey

发明人： Scott Salys ,  Chris Parrillo ,  Matt Phillips ,  Luz Padilla ,  Jnyan Patel ,  Kevin L. Morgan ,  Michael Yang ,  Sheldon Williams ,  Andrew W. McGarvey

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： An implantable lead having an elongated lead body that includes an electrical conductor extending between a distal end of the lead body and a proximal end of the lead body is disclosed. The lead further includes an electrode formed at the distal end of the lead body, the electrode being coupled to the electrical conductor and one or more passive fixation mesh sections coupled to the distal end of the lead body that promotes tissue over growth.

摘要翻译： 公开了一种具有细长引线主体的可植入引线，其包括在引线主体的远端和引线主体的近端之间延伸的电导体。 引线还包括形成在引线主体的远端处的电极，电极耦合到电导体和耦合到引线主体的远端的一个或多个被动固定网孔部分，其促进组织过度生长。

公开(公告)号：US20080027083A1

公开(公告)日：2008-01-31

申请号：US11782704

申请日：2007-07-25

申请人： Michael Yang ,  Robert Cherney ,  Martin Eastgate ,  Siva Prasad ,  Zili Xiao

发明人： Michael Yang ,  Robert Cherney ,  Martin Eastgate ,  Siva Prasad ,  Zili Xiao

IPC分类号： A61K31/517 ,  A61P17/06 ,  A61P19/02 ,  A61P25/28 ,  A61P3/00 ,  A61P3/04 ,  A61P3/10 ,  A61P31/18 ,  A61P35/00 ,  A61P9/12 ,  C07D239/84

CPC分类号： C07D403/12 ,  C07D207/273 ,  C07D317/72 ,  Y02P20/55

摘要： The present invention provides a novel antagonist or partial agonists/antagonists of MCP-1 receptor activity: N-((1R,2S,5R)-5-(isopropyl(methyl)amino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino)pyrrolidin-1-yl)cyclohexyl)acetamide, or a pharmaceutically acceptable salt, solvate or prodrug, thereof, having an unexpected combination of desirable pharmacological characteristics. Crystalline forms of the present invention are also provided. Pharmaceutical compositions containing the same and methods of using the same as agents for the treatment of inflammatory diseases, allergic, autoimmune, metabolic, cancer and/or cardiovascular diseases is also an objective of this invention. The present disclosure also provides a process for preparing compounds of Formula (I), including N-((1R,2S,5R)-5-(isopropyl(methyl)amino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino)pyrrolidin-1-yl)cyclohexyl)acetamide: wherein R1, R8, R9, R10, and are as described herein. Compounds that are useful intermediates of the process are also provided herein.

摘要翻译： 本发明提供MCP-1受体活性的新型拮抗剂或部分激动剂/拮抗剂：N - （（1R，2S，5R）-5-（异丙基（甲基）氨基）-2 - （（S） -3-（6-（三氟甲基）喹唑啉-4-基氨基）吡咯烷-1-基）环己基）乙酰胺或其药学上可接受的盐，溶剂合物或前药，具有期望的药理学特征的意想不到的组合。 还提供了本发明的结晶形式。 含有该组合物的药物组合物以及使用其作为治疗炎性疾病，过敏性，自身免疫性，代谢性，癌症和/或心血管疾病的药剂的方法也是本发明的目的。 本公开还提供制备式（I）化合物的方法，包括N - （（1R，2S，5R）-5-（异丙基（甲基）氨基）-2 - （（S）-2-氧代-3 - （6-（三氟甲基）喹唑啉-4-基氨基）吡咯烷-1-基）环己基）乙酰胺其中R 1，R 8，R 9， R SUP，R 10，并且如本文所述。 本文还提供了该方法有用中间体的化合物。

公开(公告)号：US20070239244A1

公开(公告)日：2007-10-11

申请号：US11691335

申请日：2007-03-26

申请人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

发明人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

IPC分类号： A61N1/05

CPC分类号： A61N1/059 ,  A61N1/057 ,  A61N1/0587 ,  A61N2001/058

摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the percaridal space to anchor the distal end portion of the lead body relative to the pericardial tissue.

摘要翻译： 心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。 远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。 远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开 以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。 导线部件在输送到大面积空间之后，再膨胀至其正常状态，以相对于心包组织锚固引线主体的远端部分。

公开(公告)号：US20060198048A1

公开(公告)日：2006-09-07

申请号：US11073267

申请日：2005-03-04

申请人： Eric Flint ,  Wen-Chien Hsiao ,  Yiping Hsiao ,  Michael Yang

发明人： Eric Flint ,  Wen-Chien Hsiao ,  Yiping Hsiao ,  Michael Yang

IPC分类号： G11B5/147

CPC分类号： G11B5/3116 ,  G11B5/31 ,  G11B5/313

摘要： A disk drive thin-film write head structure has a pole tip structure with reduced susceptibility to corrosion. The write head has a first ferromagnetic pole tip that includes a pedestal pole layer and a capping layer on the pedestal pole layer. The capping layer has an extension and the write gap is located between the capping layer extension and the second pole tip. Substantially the entire thickness of the pedestal pole layer is formed of a lower-moment alloy and the capping layer is formed of a higher-moment alloy and is made thick enough to compensate for the lower-moment alloy in the pedestal pole layer. The pedestal pole layer may be a bilayer of two different alloys with the upper layer in the bilayer having a higher moment. The width of the pedestal pole layer is substantially reduced to reduce the pole tip area exposed. The reduced pole tip area and the increased use of lower-moment alloys enable a thinner protective film to be used to protect the pole tips from corrosion.

摘要翻译： 磁盘驱动器薄膜写头结构具有磁极尖端结构，具有降低的腐蚀敏感性。 写头具有第一铁磁极端头，其包括基座极层和底座极层上的覆盖层。 封盖层具有延伸部，写入间隙位于封盖层延伸部和第二极端部之间。 基座极层的整个厚度基本上由较低的力矩合金形成，并且盖层由更高的力矩合金形成，并且被制成足够厚以补偿底座极层中的较小的力矩合金。 底座极层可以是两个不同合金的双层，双层中的上层具有较高的时间。 底座极层的宽度大大减小，以减小露出的极尖面积。 减小的极端面积和增加使用较低的力矩合金使得可以使用更薄的保护膜来保护极尖免受腐蚀。

公开(公告)号：US20060148808A1

公开(公告)日：2006-07-06

申请号：US11375125

申请日：2006-03-14

申请人： Albert Robichaud ,  Taekyu Lee ,  Wei Deng ,  Ian Mitchell ,  Michael Yang ,  Simon Haydar ,  Wenting Chen ,  Christopher McClung ,  Emilie Calvello ,  David Zawrotny

发明人： Albert Robichaud ,  Taekyu Lee ,  Wei Deng ,  Ian Mitchell ,  Michael Yang ,  Simon Haydar ,  Wenting Chen ,  Christopher McClung ,  Emilie Calvello ,  David Zawrotny

IPC分类号： A61K31/498 ,  C07D487/14

CPC分类号： C07D471/06 ,  C07D221/18 ,  C07D223/32 ,  C07D471/16 ,  C07D487/06 ,  C07D491/06 ,  C07D495/06 ,  C07D513/06 ,  C07D513/16 ,  C07D519/00

摘要： The present invention is directed to compounds useful for treating addictive behavior and sleep disorders represented by structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6a, R6b, R7, R8, R9, X, b, k, m, and n, and the dashed lines are described herein. The compounds used in the method of treatment of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including addictive behavior and sleep disorders.

摘要翻译： 本发明涉及可用于治疗由结构式（I）或其药学上可接受的盐形式表示的成瘾行为和睡眠障碍的化合物，其中R 1，R 5， R 6a，R 6b，R 7，R 8，R 9， X，b，k，m和n，这里描述虚线。 用于治疗本发明的方法中的化合物是血清素激动剂和拮抗剂，并且可用于控制或预防中枢神经系统疾病，包括上瘾行为和睡眠障碍。

公开(公告)号：US20060124468A1

公开(公告)日：2006-06-15

申请号：US11345011

申请日：2006-02-01

申请人： Nicolay Kovarsky ,  Michael Yang ,  Dmitry Lubomirsky

发明人： Nicolay Kovarsky ,  Michael Yang ,  Dmitry Lubomirsky

IPC分类号： C25D7/12

CPC分类号： H01L21/2885 ,  C25D17/001

摘要： Embodiments of the invention generally provide a substrate processing system and method. The substrate processing system generally includes a fluid basin configured to contain a plating solution therein, an anode assembly positioned in a lower portion of the fluid basin, a separation membrane positioned across the fluid basin above the anode assembly, a diffusion member positioned across the fluid basin above the separation membrane, and a plating membrane positioned across the fluid basin above the diffusion member. The plating method generally includes immersing the substrate in a plating solution, the plating solution containing metal ions to be plated, contacting a plating surface of the semiconductor substrate with a plating membrane, applying a plating bias to the semiconductor substrate to plate the metal ions in the plating solution positioned adjacent the plating surface of the substrate, removing the plating surface from contact with the plating membrane for a predetermined period of time, and recontacting the plating surface with the plating membrane to continue plating the metal ions onto the plating surface.

摘要翻译： 本发明的实施例通常提供一种基板处理系统和方法。 衬底处理系统通常包括配置成在其中容纳电镀液的流体池，位于流体池的下部的阳极组件，位于阳极组件上方的横跨流体池的隔离膜，跨过流体定位的扩散构件 在分离膜之上的盆地，以及位于扩散构件上方的横跨流体池的镀膜。 电镀方法通常包括将衬底浸入电镀溶液中，镀敷溶液含有待镀覆的金属离子，与半导体衬底的电镀表面接触镀覆膜，向半导体衬底施加电镀偏压以将金属离子 所述电镀液位于所述基板的电镀面附近，除去所述电镀表面与所述镀膜接触预定的时间，并且将所述电镀表面与所述电镀膜重新接触以继续将所述金属离子电镀到所述电镀表面上。

公开(公告)号：US07025861B2

公开(公告)日：2006-04-11

申请号：US10360234

申请日：2003-02-06

申请人： Nicolay Kovarsky ,  Michael Yang ,  Dmitry Lubomirsky

发明人： Nicolay Kovarsky ,  Michael Yang ,  Dmitry Lubomirsky

IPC分类号： C25F3/30 ,  B23H5/06 ,  C25D7/12 ,  C25D5/22

CPC分类号： H01L21/2885 ,  C25D17/001

摘要： Embodiments of the invention generally provide a substrate processing system and method. The substrate processing system generally includes a fluid basin configured to contain a plating solution therein, an anode assembly positioned in a lower portion of the fluid basin, a separation membrane positioned across the fluid basin above the anode assembly, a diffusion member positioned across the fluid basin above the separation membrane, and a plating membrane positioned across the fluid basin above the diffusion member. The plating method generally includes immersing the substrate in a plating solution, the plating solution containing metal ions to be plated, contacting a plating surface of the semiconductor substrate with a plating membrane, applying a plating bias to the semiconductor substrate to plate the metal ions in the plating solution positioned adjacent the plating surface of the substrate, removing the plating surface from contact with the plating membrane for a predetermined period of time, and recontacting the plating surface with the plating membrane to continue plating the metal ions onto the plating surface.

公开(公告)号：US20160378497A1

公开(公告)日：2016-12-29

申请号：US14752745

申请日：2015-06-26

申请人： Roger Gramunt ,  Rammohan Padmanabhan ,  Gerardo A. Fernandez ,  David K. Li ,  Julio Gaga ,  Michael Yang ,  Jonathan C. Hall

发明人： Roger Gramunt ,  Rammohan Padmanabhan ,  Gerardo A. Fernandez ,  David K. Li ,  Julio Gaga ,  Michael Yang ,  Jonathan C. Hall

IPC分类号： G06F9/38 ,  G06F9/30

CPC分类号： G06F9/384 ,  G06F9/30145 ,  G06F9/3851

摘要： Embodiments of systems, methods, and apparatuses for thread selection and reservation station binding are disclosed. In an embodiment, an apparatus includes allocation hardware including reservation station binding logic to bind an operation to one of a plurality of reservation stations. In an embodiment, an apparatus includes thread selection logic to select a thread to be processed by a pipeline stage, wherein the thread selection logic to evaluate a plurality of conditions to select a thread, wherein the conditions include if a thread is active, if a thread has operations in an instruction queue, if a thread has available resources, and if a thread has no known stall.

摘要翻译： 公开了用于线程选择和预留站绑定的系统，方法和装置的实施例。 在一个实施例中，一种装置包括分配硬件，包括保留站绑定逻辑以将操作绑定到多个保留站之一。 在一个实施例中，一种装置包括线程选择逻辑，用于选择要由流水线级处理的线程，其中线程选择逻辑用于评估多个条件以选择线程，其中条件包括线程是否活动，如果 线程在指令队列中有操作，如果线程有可用资源，并且线程没有已知的停顿。

公开(公告)号：US09460697B1

公开(公告)日：2016-10-04

申请号：US13950280

申请日：2013-07-25

申请人： Michael Yang

发明人： Michael Yang

IPC分类号： G10H1/36 ,  G10H1/08

CPC分类号： G10H1/08 ,  G10H1/46 ,  G10H7/008 ,  G10H2210/381 ,  G10H2210/385 ,  G10H2220/086 ,  G10H2250/035

摘要： A system and method are provided for mixing song data based on measure groupings. A player or program may recognize measure groupings in a song through identifying cuepoints. The player or program may use the cuepoints and/or other identifiers of measure groupings to generate a transition between the song and other songs. Parts of one or both songs may be time-stretched, or frames may be added or deleted, such that the beats in both songs are substantially aligned during the transition. The system and method may also involve altering the sequence of frames in one or both of the songs, so that the transition may have various sonic qualities as desired by a user. A choice of transition modes may be provided via a user interface that allow the user some control over when and how transitions between songs are executed.

摘要翻译： 提供了一种基于测量分组来混合歌曲数据的系统和方法。 玩家或节目可以通过识别节点来识别歌曲中的度量分组。 播放器或程序可以使用度量分组的点和/或其他标识符来产生歌曲和其他歌曲之间的转换。 一首或两首歌曲的部分可能是时间延长的，或者可以添加或删除帧，使得两首歌曲中的节拍在转换期间基本对准。 系统和方法还可以涉及改变一个或两个歌曲中的帧序列，使得转换可以具有如用户所期望的各种声音质量。 转换模式的选择可以通过用户界面来提供，其允许用户对歌曲之间的转换何时以及如何进行控制。