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公开(公告)号：US20130336917A1
公开(公告)日：2013-12-19
申请号：US13917323
申请日：2013-06-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述包含聚合物的组合物; 非生理pH溶液; 和可视化代理; 其中所述聚合物可溶于所述非生理pH溶液并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号：US11998563B2
公开(公告)日：2024-06-04
申请号：US17744192
申请日：2022-05-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61L24/0089 , A61L24/046 , A61K47/32 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20220273700A1
公开(公告)日：2022-09-01
申请号：US17744192
申请日：2022-05-13
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785 , A61K9/00 , A61K31/78 , A61L24/00 , A61L24/04
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US11160557B2
公开(公告)日：2021-11-02
申请号：US16250880
申请日：2019-01-17
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Terrance Tran
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
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公开(公告)号：US10588923B2
公开(公告)日：2020-03-17
申请号：US16232929
申请日：2018-12-26
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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Patent Agency Ranking
公开(公告)号：US20190192726A1
公开(公告)日：2019-06-27
申请号：US16287797
申请日：2019-02-27
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20190134078A1
公开(公告)日：2019-05-09
申请号：US16232929
申请日：2018-12-26
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
IPC: A61K31/785 , A61L24/00 , A61K9/00 , A61L24/04 , A61K31/78
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US10226533B2
公开(公告)日：2019-03-12
申请号：US14678514
申请日：2015-04-03
Applicant: MIcroVention, Inc.
Inventor： Gregory M. Cruise , Clayton G. Harris , Michael J. Constant
IPC: A61K47/32 , A61K31/7068 , A61K31/787 , C07H19/06 , C07F15/00 , A61K9/00 , A61K49/04 , A61L31/14 , A61L31/16 , A61L31/18 , A61K47/58
Abstract: Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
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公开(公告)号：US09937201B2
公开(公告)日：2018-04-10
申请号：US15142395
申请日：2016-04-29
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Joshua Garretson
CPC classification number: A61K31/785 , A61K9/0024 , A61K31/78 , A61K47/32 , A61L24/0089 , A61L24/046 , A61L2430/36
Abstract: Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US20170007264A1
公开(公告)日：2017-01-12
申请号：US15272305
申请日：2016-09-21
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Terrance T. Tran
CPC classification number: A61B17/12113 , A61B17/12181 , A61B90/39 , A61B2017/00004 , A61B2017/1205 , A61B2090/3966 , A61K49/0404 , A61L24/001 , A61L24/0031 , A61L24/046 , A61L27/16 , A61L27/18 , A61L27/56 , A61L31/048 , A61L31/06 , A61L31/146 , A61L31/18 , A61L2430/36 , C08L39/06 , C08L71/02
Abstract: Described are devices for implantation comprising a hydrogel filament wherein the hydrogel filament includes a low molecular weight ethylenically unsaturated macromer, an ethylenically unsaturated monomer, and a visualization agent. Methods of making and using these devices are also described.
Abstract translation: 描述了用于植入的装置，其包括水凝胶细丝，其中水凝胶细丝包括低分子量烯键式不饱和大分子单体，烯属不饱和单体和可视化试剂。 还描述了制造和使用这些装置的方法。
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