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公开(公告)号：US20240108781A1
公开(公告)日：2024-04-04
申请号：US18482688
申请日：2023-10-06
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US10258716B2
公开(公告)日：2019-04-16
申请号：US15491864
申请日：2017-04-19
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号：US10194915B2
公开(公告)日：2019-02-05
申请号：US15272305
申请日：2016-09-21
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Terrance T. Tran
IPC: A61B17/00 , A61B17/12 , A61B90/00 , A61K49/04 , A61L24/00 , A61L24/04 , A61L27/16 , A61L27/18 , A61L27/56 , A61L31/04 , A61L31/06 , A61L31/14 , A61L31/18 , C08L39/06 , C08L71/02
Abstract: Described are devices for implantation comprising a hydrogel filament wherein the hydrogel filament includes a low molecular weight ethylenically unsaturated macromer, an ethylenically unsaturated monomer, and a visualization agent. Methods of making and using these devices are also described.
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公开(公告)号：US20160243273A1
公开(公告)日：2016-08-25
申请号：US14736145
申请日：2015-06-10
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述了包含生物相容性聚合物的聚合物组合物，其包括与可视化试剂和非生理pH溶液的生物可降解连接; 其中所述生物相容性聚合物可溶于非生理pH溶液中，并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号：US20170216484A1
公开(公告)日：2017-08-03
申请号：US15491864
申请日：2017-04-19
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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Patent Agency Ranking
公开(公告)号：US09486221B2
公开(公告)日：2016-11-08
申请号：US13899357
申请日：2013-05-21
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Terrance T. Tran
CPC classification number: A61B17/12113 , A61B17/12181 , A61B90/39 , A61B2017/00004 , A61B2017/1205 , A61B2090/3966 , A61K49/0404 , A61L24/001 , A61L24/0031 , A61L24/046 , A61L27/16 , A61L27/18 , A61L27/56 , A61L31/048 , A61L31/06 , A61L31/146 , A61L31/18 , A61L2430/36 , C08L39/06 , C08L71/02
Abstract: Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations with radiopaque hydrogel filaments with delayed controlled rates of expansion permitting the repositioning of the device once inside the structure or malformation. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.
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公开(公告)号：US20150283306A1
公开(公告)日：2015-10-08
申请号：US14678525
申请日：2015-04-03
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise , Wendy Graczyk
CPC classification number: A61L31/048 , A61L31/145 , A61L31/18 , A61L2300/102 , A61L2430/36 , C08L33/26 , C08L33/10
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
Abstract translation: 本文描述的是用不透射线水凝胶细丝阻塞血管结构和血管畸形的装置，组合物，系统和方法。 长丝不能含有支撑构件，可以兼容CT和MR。 还公开了形成这种细丝的方法。
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公开(公告)号：US20150190553A1
公开(公告)日：2015-07-09
申请号：US14661995
申请日：2015-03-18
Applicant: MicroVention, Inc.
Inventor： Michael Constant , Edward Michael Keeley , Joshua Garretson , Gregory M. Cruise
CPC classification number: A61L31/048 , A61K9/0019 , A61K9/0024 , A61K47/30 , A61K47/34 , A61K49/0404 , A61K49/126 , A61K51/1213 , A61L31/145 , A61L31/18 , A61L2430/36 , Y10T428/298 , C08L33/26
Abstract: Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed.
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公开(公告)号：US20140107251A1
公开(公告)日：2014-04-17
申请号：US14054515
申请日：2013-10-15
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
IPC: A61L24/06
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述了包含生物相容性聚合物的聚合物组合物，其包括与可视化试剂和非生理pH溶液的生物可降解连接; 其中所述生物相容性聚合物可溶于非生理pH溶液中，并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号：US20190192726A1
公开(公告)日：2019-06-27
申请号：US16287797
申请日：2019-02-27
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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