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公开(公告)号:US08834351B2
公开(公告)日:2014-09-16
申请号:US13048492
申请日:2011-03-15
CPC分类号: A61L27/3633 , A61F2/2475 , A61L27/3604 , A61L27/3641 , A61L27/3645 , A61L27/3839
摘要: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
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公开(公告)号:US08641776B2
公开(公告)日:2014-02-04
申请号:US13048458
申请日:2011-03-15
IPC分类号: A61F2/02
CPC分类号: A61B17/12 , A61F2/07 , A61F2/2475 , A61F2002/075 , A61F2002/077
摘要: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
摘要翻译: 本发明在一个方面涉及用生物材料治疗血管血管。 生物材料可以是加强和/或支持血管壁的可重塑材料。 另外,生物材料可以包括多种天然存在或添加的生物活性剂和/或活细胞群体。
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公开(公告)号:US08066733B2
公开(公告)日:2011-11-29
申请号:US12338731
申请日:2008-12-18
申请人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
发明人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
IPC分类号: A61M29/00
CPC分类号: A61B17/00008 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/12181 , A61B2017/1205
摘要: Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the percutaneous delivery of an occlusion device inverted within a cannula, its deployment and filling, so as to occlude or obliterate a portion of a vascular vessel.
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公开(公告)号:US07637937B2
公开(公告)日:2009-12-29
申请号:US11099713
申请日:2005-04-06
申请人: Brian C. Case , Jacob A. Flagle
发明人: Brian C. Case , Jacob A. Flagle
IPC分类号: A61F2/06
CPC分类号: A61F2/2418 , A61F2/2475 , A61F2/90 , A61F2002/30014 , A61F2002/3011 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0002 , A61F2230/0017 , A61F2230/0054 , A61F2250/0018 , A61F2250/0036
摘要: Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. Embodiments of the invention relate to medical devices comprising a frame having cross-section that can substantially conform to body vessel shapes that have elliptical or circular cross-sections, and dynamically respond to changes in the cross-section of a body vessel. Frames with directionally-dependent radial compressibility or expandability characteristics are also provided. Medical devices comprising a frame and one or more valve members adapted to regulate fluid flow in a body vessel, such as a vein, are also provided.
摘要翻译: 提供了用于植入体内的医疗装置及其使用和制造方法。 本发明的实施例涉及包括框架的医疗装置,该框架具有基本上符合具有椭圆形或圆形横截面的身体血管形状的横截面,并且动态地响应身体血管横截面的变化。 还提供了具有方向依赖的径向压缩性或可扩展性特征的框架。 还提供了包括框架和适于调节诸如静脉的体容器中的流体流动的一个或多个阀构件的医疗装置。
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公开(公告)号:US20090216321A1
公开(公告)日:2009-08-27
申请号:US12437731
申请日:2009-05-08
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2230/0026 , A61F2230/0067 , A61F2230/008 , A61F2230/0095 , A61F2250/0067
摘要: A prosthetic valve includes a support frame, a leaflet attached to the support frame, and a bioactive agent associated with the leaflet. A first free edge of the leaflet permits fluid flow through a body vessel in a first direction and substantially prevents fluid flow through the body vessel in a second, opposite direction. A second free edge of the leaflet at least partially defines an opening for permitting a controlled amount of fluid flow through the body vessel.
摘要翻译: 假体瓣膜包括支撑框架,附接到支撑框架的小叶以及与小叶相关联的生物活性剂。 小叶的第一自由边允许流体沿着第一方向流过身体容器,并且基本上防止流体沿第二相反方向流过身体血管。 叶片的第二自由边缘至少部分地限定了允许受控量的流体流过身体容器的开口。
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公开(公告)号:US20090099589A1
公开(公告)日:2009-04-16
申请号:US12338731
申请日:2008-12-18
申请人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
发明人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
CPC分类号: A61B17/00008 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/12181 , A61B2017/1205
摘要: Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the percutaneous delivery of an occlusion device inverted within a cannula, its deployment and filling, so as to occlude or obliterate a portion of a vascular vessel.
摘要翻译: 描述了用于实现血管血管阻塞的装置,方法和系统。 经皮手术可用于闭塞和闭塞较大的隐静脉,例如用于治疗由静脉回流引起的静脉曲张病变。 某些实施方案包括在插管内反转的闭塞装置的经皮递送,其展开和填充,以封闭或消除血管容器的一部分。
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公开(公告)号:US20090069838A1
公开(公告)日:2009-03-12
申请号:US12271401
申请日:2008-11-14
申请人: Ram H. Paul , Jacob A. Flagle , Brian C. Case
发明人: Ram H. Paul , Jacob A. Flagle , Brian C. Case
IPC分类号: A61M29/02
CPC分类号: A61L29/005 , A61B17/12109 , A61B17/12136 , A61B17/1219 , A61B2017/1205
摘要: Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment and filling of an inflatable occlusion device via a percutaneous procedure, so as to occlude or obliterate a portion of a vascular vessel.
摘要翻译: 描述了用于实现血管血管阻塞的装置,方法和系统。 经皮手术可用于闭塞和闭塞较大的隐静脉,例如用于治疗由静脉回流引起的静脉曲张病变。 某些实施方案包括经由经皮程序展开和填充可充气闭塞装置,从而封闭或消除血管容器的一部分。
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38.
公开(公告)号:US09307995B2
公开(公告)日:2016-04-12
申请号:US11763773
申请日:2007-06-15
申请人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
发明人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
CPC分类号: A61B17/12031 , A61B17/12022 , A61B17/12109 , A61B17/12181 , A61B17/1219 , A61B2017/00778 , A61B2017/00867 , A61B2017/00898 , A61B2017/1205 , A61B2017/22038
摘要: Described are devices, methods, and systems for achieving occlusion of vascular vessels. Further described are certain reduced or low profile procedures and devices for the percutaneous occlusion of the saphenous vein, such as in the treatment of a varicose vein condition caused by venous reflux. Devices and procedures can involve an endoluminal delivery device having an atraumatic distal end, that is advancable through a vascular vessel, and an occlusion device received on the endoluminal delivery device. The endoluminal delivery device can have one or more adaptations for releasably receiving the occlusion device. The occlusion device can include a sponge form material. The occlusion device can include a remodelable material or a synthetic material. The occlusion device can include an anchor.
摘要翻译: 描述了用于实现血管血管闭塞的装置,方法和系统。 进一步描述了用于经皮闭塞隐静脉的某些缩减或低调程序和装置,例如用于治疗由静脉回流引起的静脉曲张病症。 装置和程序可以包括具有无创损伤远端的腔内输送装置,其可通过血管容器和通过内腔输送装置接收的闭塞装置。 腔内输送装置可具有用于可释放地接收闭塞装置的一种或多种适应。 闭塞装置可以包括海绵形式的材料。 闭塞装置可包括可重塑材料或合成材料。 遮挡装置可以包括锚固件。
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公开(公告)号:US08398663B2
公开(公告)日:2013-03-19
申请号:US12781300
申请日:2010-05-17
申请人: Ram H. Paul, Jr. , Brian C. Case , Jacob A. Flagle
发明人: Ram H. Paul, Jr. , Brian C. Case , Jacob A. Flagle
IPC分类号: A61B17/22
CPC分类号: A61B17/3207 , A61B17/320725 , A61B2017/22097
摘要: Valvulotome devices and methods are provided. Valvulotome devices include one or more valvulotome arms that have a u-shaped curved body with opposing arms and a base portion that extends between the arms. The valvulotome arm defines a notch open at one end on one of the arms and extending into the base portion of the u-shaped curved body. The notch defines an angled surface that provides a cutting edge. Methods of making valvulotome devices are also described.
摘要翻译: 提供瓣膜切除装置和方法。 瓣膜切开装置包括一个或多个瓣膜切开臂,其具有带相对臂的u形弯曲体和在臂之间延伸的基部。 瓣膜切开臂限定了在一个臂上的一端处开口并且延伸到U形弯曲体的基部中的凹口。 切口限定了提供切削刃的成角度的表面。 还描述了制造瓣膜切开术装置的方法。
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公开(公告)号:US20100286719A1
公开(公告)日:2010-11-11
申请号:US12781300
申请日:2010-05-17
申请人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
发明人: Ram H. Paul , Brian C. Case , Jacob A. Flagle
IPC分类号: A61B17/22
CPC分类号: A61B17/3207 , A61B17/320725 , A61B2017/22097
摘要: Valvulotome devices and methods are provided. Valvulotome devices include one or more valvulotome arms that have a u-shaped curved body with opposing arms and a base portion that extends between the arms. The valvulotome arm defines a notch open at one end on one of the arms and extending into the base portion of the u-shaped curved body. The notch defines an angled surface that provides a cutting edge. Methods of making valvulotome devices are also described.
摘要翻译: 提供瓣膜切除装置和方法。 瓣膜切开装置包括一个或多个瓣膜切开臂,其具有带相对臂的u形弯曲体和在臂之间延伸的基部。 瓣膜切开臂限定了在一个臂上的一端处开口并且延伸到U形弯曲体的基部中的凹口。 切口限定了提供切削刃的成角度的表面。 还描述了制造瓣膜切开术装置的方法。
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