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149 条记录 (耗时 0.051 秒)

    Steroid eluting pacing tip electrode
    33.
    发明授权
    Steroid eluting pacing tip electrode 有权
    类固醇洗脱起搏电极

    公开(公告)号：US08175723B2

    公开(公告)日：2012-05-08

    申请号：US12505226

    申请日：2009-07-17

    申请人： Ravi Jain

    发明人： Ravi Jain

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0568

    摘要： An implantable cardioverter defibrillator (ICD) including a set of leads having electrodes disposed therein. The electrodes may include a weld electrode connected to an internal wire of the lead and the ICD and a tip electrode. The tip electrode may have a set of grooves or cut out regions in its outer surface to provide edge effects for currents applied through the tip electrode. The grooves or cut out regions may form gaps in the surface of the tip electrode exposing a medical compound that is housed within the tip electrode. The medical compound may elute through the gaps.

    摘要翻译： 一种植入式心律转复除颤器（ICD），包括一组具有设置在其中的电极的引线。 电极可以包括连接到引线和ICD的内部引线和尖端电极的焊接电极。 尖端电极可以在其外表面中具有一组凹槽或切出区域，以对通过尖端电极施加的电流提供边缘效应。 凹槽或切出区域可以在尖端电极的表面中形成间隙，暴露出容纳在尖端电极内的医疗化合物。 药物化合物可以通过缝隙洗脱。

    Geographically localizing mobile communciation devices
    36.
    发明授权
    Geographically localizing mobile communciation devices 有权
    地理位置移动通信设备

    公开(公告)号：US07983691B1

    公开(公告)日：2011-07-19

    申请号：US11557097

    申请日：2006-11-06

    申请人： Bernard Wong ,  Samir Goel ,  Ravi Jain

    发明人： Bernard Wong ,  Samir Goel ,  Ravi Jain

    IPC分类号： H04W24/00 ,  H04M3/42

    CPC分类号： H04W4/02 ,  G01S5/0284 ,  H04M7/006 ,  H04M2207/18 ,  H04M2207/20 ,  H04M2242/30 ,  H04W64/003

    摘要： This specification describes technologies relating to geographically localizing mobile communication devices. In general, one aspect of the subject matter described in this specification can be embodied in a method that includes receiving information corresponding to a location of a wireless landmark in a mobile communication network. The method also includes communicating with the wireless landmark to estimate the location of a first node in the mobile communication network proximate to the wireless landmark. Other embodiments of this aspect include corresponding systems, apparatus, and computer program products.

    摘要翻译： 本说明书描述了涉及地理位置移动通信设备的技术。 通常，本说明书中描述的主题的一个方面可以体现在包括在移动通信网络中接收对应于无线地标的位置的信息的方法中。 该方法还包括与无线地标通信以估计接近无线地标的移动通信网络中的第一节点的位置。 该方面的其他实施例包括相应的系统，装置和计算机程序产品。

    MECHANISM FOR, AND METHOD OF, ATTACHING A LEAD CONDUCTOR CABLE TO A LEAD ELECTRODE
    37.
    发明申请
    MECHANISM FOR, AND METHOD OF, ATTACHING A LEAD CONDUCTOR CABLE TO A LEAD ELECTRODE 有权
    将引线电缆连接到引线电极的机理及方法

    公开(公告)号：US20110137392A1

    公开(公告)日：2011-06-09

    申请号：US13029924

    申请日：2011-02-17

    申请人： Matt Randle ,  Ravi Jain ,  Peter Fong

    发明人： Matt Randle ,  Ravi Jain ,  Peter Fong

    IPC分类号： A61N1/05

    CPC分类号： A61N1/05 ,  H01R4/5058 ,  H01R2201/12

    摘要： A cardio electrotherapy lead is disclosed herein. In one embodiment, the lead includes a tubular body, a conductor cable and an electrode. The conductor cable longitudinally extends through the tubular body and includes a distal end. The electrode is located on the tubular body and includes an attachment mechanism mechanically coupling the lead distal end to the electrode.

    摘要翻译： 本文公开了一种心脏电疗引线。 在一个实施例中，引线包括管状体，导体电缆和电极。 导体电缆纵向延伸穿过管状主体并且包括远端。 电极位于管状体上，并且包括将引线远端机械连接到电极的附接机构。

    Compositions and their uses directed to PTPRU
    38.
    发明授权
    Compositions and their uses directed to PTPRU 失效
    组合及其针对PTPRU的用途

    公开(公告)号：US07897583B2

    公开(公告)日：2011-03-01

    申请号：US11915309

    申请日：2006-05-24

    申请人： Robert McKay ,  Ravi Jain ,  Kenneth W. Dobie ,  Sanjay K. Pandey ,  Sanjay Bhanot

    发明人： Robert McKay ,  Ravi Jain ,  Kenneth W. Dobie ,  Sanjay K. Pandey ,  Sanjay Bhanot

    IPC分类号： A61K48/00 ,  C07H21/02 ,  C07H21/04

    CPC分类号： C12N15/1137 ,  C12N2310/11 ,  C12N2310/315 ,  C12N2310/321 ,  C12N2310/3341 ,  C12N2310/341 ,  C12N2310/346 ,  C12Y301/03048 ,  C12N2310/3525

    摘要： Disclosed herein are compounds, compositions and methods for modulating the expression of PTPRU in a cell, tissue or animal. Also provided are methods of active target segment validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders. Also provided are methods for the prevention, amelioration and/or treatment of diabetes, obesity, insulin resistance, insulin deficiency, hypercholesterolemia, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hyperfattyacidemia, liver steatosis, steatohepatitis, non-alcoholic steatohepatitis, metabolic syndrome, cardiovascular disease and coronary heart disease by administration of antisense compounds targeted to PTPRU.

    摘要翻译： 本文公开了用于调节细胞，组织或动物中PTPRU表达的化合物，组合物和方法。 还提供了主动目标段验证的方法。 还提供了所公开的化合物和组合物在制备用于治疗疾病和病症的药物中的用途。 还提供了用于预防，改善和/或治疗糖尿病，肥胖症，胰岛素抵抗，胰岛素缺乏，高胆固醇血症，高血糖症，高脂血症，高甘油三酯血症，高脂肪肝，肝脂肪变性，脂肪性肝炎，非酒精性脂肪性肝炎，代谢综合征，心血管疾病和 通过给予针对PTPRU的反义化合物的冠心病。