摘要:
An apparatus is provided for applying to a surface of mammalian tissue including soft, living tissue an initially fluent material and then activating the material by exposure to an energy source. The material may be a liquid capable of polymerization to a non-fluent state by exposure to actinic light. The device, and methods that may be practised in association with the device, enable a wide range of medical conditions to be treated including, for example, the application of a barrier to soft tissue to prevent post-surgical adhesions.
摘要:
A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed by the polymeric material, the material may be selectively heated and shaped in vivo without a corresponding heating of adjacent tissues or fluids to unacceptable levels. The apparatus comprises a catheter having a shaping element positioned near its distal end. An emitter provided with light from at least one optical fiber is positioned within the shaping element. The emitter serves to provide a moldable polymeric article positioned on the shaping element with a substantially uniform light field, thereby allowing the article to be heated and molded at a desired treatment site in a body lumen.
摘要:
A catheter for delivering radiant energy, such as a laser beam, is used in a technique to controllably apply the radiant energy in a patient's body, such as in a blood vessel. The radiant energy is applied in a manner which erodes biological material and may be used to drill through vascular obstructions. The catheter emits the radiant energy from its distal end in a pattern which defines a relatively small working region in which the energy density level is sufficiently high to remove the biological material. The energy distribution is substantially uniform across the beam. Distally beyond the working region, the energy density of the beam decays sharply so that biological material beyond the working region is not removed.
摘要:
Medical device and methods are provided for controlled drug delivery in a cardiac patient. The device includes an implantable drug delivery module comprising reservoirs containing a drug and a control means for selectively releasing an effective amount of drug from each reservoir; one or more electrodes or sensors for cardiac monitoring, stimulation, or both; and a microcontroller for controlling operational interaction of the drug delivery module and the cardiac electrode. The electrodes may comprise ECG monitoring, cardioversion, or cardiac pacing electrodes. A medical device also is provided for controlled delivery of drug to a patient having congestive heart failure, which includes an implantable drug delivery module comprising a natriuretic peptide and a release mechanism for selectively releasing a pharmaceutically effective amount of the natriuretic peptide into the patient; and a microcontroller for controlling the release mechanism, for example, in response to one or more monitored patient parameters.
摘要:
A method of producing stable, non-fogging fragrances for automobiles and other vehicular environments. A non-fogging fragrance constructed by combining ingredients individually passing a standard fogging test. Non-fogging solvents identified to maintain a liquid fragrance and prevent freezing at low temperatures. The fragrance chemically stabilized by storage in a tightly sealed container covered with an inert gas. The sealed container also eliminates unwanted vapor emissions in the vehicle. The fragrance is provided on demand as a spray, ensuring delivery with uniform odor integrity over the lifetime of the product.
摘要:
Devices for providing polymeric layers on the interior surface of body lumens and spaces are disclosed. The devices can include proximal and distal occlusion elements to define the treatment space and an optical emitter to provide light for a photopolymerization procedure. The devices may include a molding member for providing a thick polymeric gel. Alternatively, devices without a molding member may be used to carry out an interfacial polymerization procedure.
摘要:
An apparatus is provided for applying to a surface of mammalian tissue including soft, living tissue an initially fluent material and then activating the material by exposure to an energy source. The material may be a liquid capable of polymerization to a non-fluent state by exposure to actinic light. The device, and methods that may be practiced in association with the device, enable a wide range of medical conditions to be treated including, for example, the application of a barrier to, soft tissue to prevent post-surgical adhesions.
摘要:
Diffusing gas into and out of a liquid at a uniform rate by distributing a foam consisting of bubbles with liquid walls surrounding the gas through elongated passages defined by a corrugated surface adjacent to a smooth surface, while simultaneously providing for indirect heat - exchange of the blood foam while the foam is within the elongated passages.
摘要:
Sturdily mounting a disposable medical device by rotatably attaching a back plate to a back brace, biasing the back plate toward the medical device and employing a camming means on the back plate cooperating with a tab on the device to rotate the plate away from the device as the device is initially slid onto the mount and to return the plate to lock the device in place when the device is slid fully onto the mount.
摘要:
Monitoring the level of both opaque and clear liquids in a reservoir without contacting the liquids by providing first and second reservoir wall portions that define a region through which a light beam is passed from a light source to a light sensor so that opaque liquid extinguishes the light beam and so that the wall portions cooperate with the clear liquid to refract the light beam away from the sensor. A monitoring line segment, defined as the portion of a hypothetically unrefracted and unreflected light beam between the first and second reservoir wall portions, is a small fraction of the largest interior linear dimension of the reservoir in a plane containing the monitoring line segment and a line normal to the first reservoir wall portion.