POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS
    32.
    发明申请
    POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS 有权
    聚乙烯甘油超氧化物歧化酶

    公开(公告)号:US20080318917A1

    公开(公告)日:2008-12-25

    申请号:US11766221

    申请日:2007-06-21

    CPC分类号: A61K47/60

    摘要: Compounds and methods for utilizing compounds comprising a superoxide dismutase mimetic covalently linked to polyethylene glycol. Methods are also provided for preparing a superoxide dismutase mimetic covalently linked to a polyethylene glycol, the methods comprising reacting an activated polyethylene glycol with a superoxide, dismutase mimetic, or alternatively, reacting a superoxide dismutase mimetic with an activated polyethylene glycol. A method is also provided for preventing or treating a disease or disorder in which superoxide anions are implicated, comprising administering to a subject in need thereof, a therapeutically effective amount of a compound comprising a superoxide dismutase mimetic covalently linked to a polyethylene glycol. Methods of determining the safety and efficacy of the compounds ere also provided. Methods for determining the safety and efficacy can include methods in lab animals and humans.

    摘要翻译: 用于利用包含与聚乙二醇共价连接的超氧化物歧化酶模拟物的化合物的化合物和方法。 还提供了用于制备与聚乙二醇共价连接的超氧化物歧化酶模拟物的方法,所述方法包括使活化的聚乙二醇与超氧化物反应,模拟物歧化酶,或者将超氧化物歧化酶模拟物与活化的聚乙二醇反应。 还提供了一种用于预防或治疗涉及超氧化物阴离子的疾病或病症的方法,包括向有需要的受试者施用治疗有效量的包含与聚乙二醇共价连接的超氧化物歧化酶模拟物的化合物。 还提供了确定化合物的安全性和功效的方法。 确定安全性和功效的方法可以包括实验动物和人类的方法。

    Rubber-modified polymer blends of polycarbonate and PETG
    37.
    发明授权
    Rubber-modified polymer blends of polycarbonate and PETG 失效
    聚碳酸酯和PETG的橡胶改性聚合物共混物

    公开(公告)号:US5187230A

    公开(公告)日:1993-02-16

    申请号:US742567

    申请日:1991-08-07

    申请人: Kishore Udipi

    发明人: Kishore Udipi

    IPC分类号: C08L67/02 C08L69/00

    CPC分类号: C08L67/02 C08L69/00

    摘要: Polymer blends useful as thermoplastic molding resins comprise PC, PETG and sufficient rubber, e.g. nitrile rubber or ethylene-acrylate copolymer rubber, to enhance the moldability of the blend. Preferred blends comprise at least 30% PC, 30% PETG and 5% rubber.

    摘要翻译: 可用作热塑性模塑树脂的聚合物共混物包括PC,PETG和足够的橡胶,例如。 丁腈橡胶或乙烯 - 丙烯酸酯共聚物橡胶,以增强共混物的成型性。 优选的共混物包含至少30%的PC,30%的PETG和5%的橡胶。

    Rubber modified reaction molded nylon-6 block copolymers
    38.
    发明授权
    Rubber modified reaction molded nylon-6 block copolymers 失效
    橡胶改性反应模塑尼龙-6嵌段共聚物

    公开(公告)号:US5051469A

    公开(公告)日:1991-09-24

    申请号:US347536

    申请日:1989-05-04

    申请人: Kishore Udipi

    发明人: Kishore Udipi

    摘要: Dispersions of core-shell polymers in caprolactam solutions of telechelic polymers capable of being polymerized to form rubber-modified nylon-6 block copolymers having improved impact strength wherein the core-shell polymer comprises a crosslinked elastomer core and a hard thermoplastic polymer shell and wherein the telechelic polymers preformed or formed in situ, are capped with lactam polymerization initiator groups.

    摘要翻译: 核 - 壳聚合物在能够被聚合以形成具有改进的冲击强度的橡胶改性尼龙-6嵌段共聚物的己内酰胺溶液中的分散体,其中核 - 壳聚合物包含交联的弹性体芯和硬的热塑性聚合物壳,并且其中 预先形成或原位形成的遥爪聚合物用内酰胺聚合引发剂基团封端。

    Rubber modified reaction moldable nylon-6 compositions
    39.
    发明授权
    Rubber modified reaction moldable nylon-6 compositions 失效
    橡胶改性反应可成型尼龙-6组合物

    公开(公告)号:US4994524A

    公开(公告)日:1991-02-19

    申请号:US225111

    申请日:1988-07-27

    申请人: Kishore Udipi

    发明人: Kishore Udipi

    摘要: Dispersions of core-shell polymers in caprolactam wherein the core-shell polymer comprises a crosslinked elastomer core and a hard thermoplastic shell prepared by adding an aqueous dispersion of core-shell polymer to an aqueous solution of caprolactam, stirring the mixture to provide a uniform dispersion and evaporating water from the mixture. Such dispersions can be combined with caprolactam polymerization initiator and caprolactam polymerization catalyst to provide rubber-modified nylon-6 polymers.

    摘要翻译: 核 - 壳聚合物在己内酰胺中的分散体,其中核 - 壳聚合物包含交联弹性体芯和通过将核 - 壳聚合物的水分散体加入到己内酰胺水溶液中制备的硬质热塑性壳,搅拌混合物以提供均匀的分散体 并从混合物中蒸发水。 这种分散体可以与己内酰胺聚合引发剂和己内酰胺聚合催化剂结合以提供橡胶改性的尼龙-6聚合物。

    Polyblends of thermoplastic copolyesters and styrene acrylonitrile
copolymers
    40.
    发明授权
    Polyblends of thermoplastic copolyesters and styrene acrylonitrile copolymers 失效
    热塑性共聚酯和苯乙烯丙烯腈共聚物的共混物

    公开(公告)号:US4987187A

    公开(公告)日:1991-01-22

    申请号:US453851

    申请日:1989-12-20

    IPC分类号: C08L67/00 C08L67/02

    CPC分类号: C08L67/02

    摘要: A molding composition prepared from a blend of: (A) a copolyester of a dicarboxylic acid moiety, such as terephthalic acid or dimethyl terephthalate and a dihydric alcohol moiety, such as ethylene glycol in combination with diethylene glycol or 1,4-cyclohexanedimethanol, and (B) a copolymer prepared from a styrenic monomer and an ethylenically unsaturated nitrile, wherein articles molded from such compositions have improved clarity and toughness.