公开(公告)号：US20050054942A1

公开(公告)日：2005-03-10

申请号：US10788501

申请日：2004-02-26

申请人： Richard Melker ,  James Sackellares ,  Mark Gold

发明人： Richard Melker ,  James Sackellares ,  Mark Gold

IPC分类号： A61B5/08 ,  A61B5/083 ,  A61M5/142 ,  A61M5/172 ,  A61M16/01 ,  A61M16/10 ,  A61M37/00

CPC分类号： G01N33/50 ,  A61B5/082 ,  A61B5/4094 ,  A61B5/411 ,  A61B5/4821 ,  A61M5/142 ,  A61M5/1723 ,  A61M16/01 ,  A61M16/085 ,  A61M2016/1035 ,  A61M2230/437

摘要： The present invention includes systems and methods for monitoring therapeutic drug concentration in blood by detecting markers, such as odors, upon exhalation by a patient after the drug is taken, wherein such markers result either directly from the drug itself or from an additive combined with the drug. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor drug levels in blood. The invention further includes a reporting system capable of tracking drug concentrations in blood (remote or proximate locations) and providing the necessary alerts with regarding to ineffective or toxic drug dosages in a patient.

摘要翻译： 本发明包括通过在药物摄取之后通过检测患者呼气时检测诸如气味的标记物来监测血液中的治疗药物浓度的系统和方法，其中这样的标记物直接从药物本身或与药物本身结合的添加剂 药物。 在嗅觉标记的情况下，本发明优选利用诸如被称为“人造”或“电子”鼻子或舌头的商业装置的电子传感器技术非侵入性地监测血液中的药物水平。 本发明还包括能够跟踪血液（偏远或邻近位置）中的药物浓度并提供关于患者中无效或有毒药物剂量的必要警报的报告系统。

公开(公告)号：US5532029A

公开(公告)日：1996-07-02

申请号：US388402

申请日：1995-02-14

申请人： Ronnie S. Fuerst ,  Richard Melker ,  Christopher D. Batich

发明人： Ronnie S. Fuerst ,  Richard Melker ,  Christopher D. Batich

IPC分类号： A61K6/00 ,  A61K8/04 ,  A61K8/49 ,  A61K31/34 ,  A61Q17/04 ,  C09D7/00 ,  C11D3/40 ,  G01N31/22 ,  B32B1/06 ,  A61K7/42 ,  F42B8/14

CPC分类号： G01N31/221 ,  A61K6/0017 ,  A61K6/0058 ,  A61K8/046 ,  A61K8/4973 ,  A61Q17/04 ,  C09D7/00 ,  C11D3/40 ,  A61K2800/45 ,  Y10T428/13 ,  Y10T428/1352 ,  Y10T428/1397 ,  Y10T428/249995 ,  Y10T428/249997

摘要： This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.