公开(公告)号：US20110022036A1

公开(公告)日：2011-01-27

申请号：US12843685

申请日：2010-07-26

申请人： Rudolph W. Frey ,  Gary P. Gray ,  Neil Zepkin

发明人： Rudolph W. Frey ,  Gary P. Gray ,  Neil Zepkin

IPC分类号： A61B18/20

CPC分类号： A61F9/008 ,  A61F9/00825 ,  A61F2009/00844 ,  A61F2009/00846 ,  A61F2009/0087 ,  A61F2009/00887 ,  A61F2009/00889 ,  A61F2009/00895 ,  A61F2009/00897

摘要： There is provided a system, apparatus and methods for developing laser systems that can create a precise predetermined jigsaw capsulotomy. The systems, apparatus and methods further provide laser systems that can use a single laser as a therapeutic laser and as laser radar and that reduce the patient-to-patient variability and doctor-to-doctor variability associated with hand held apparatus for performing capsulorhexis and capsulotomies. There is further provided a precise predetermined jigsaw shot pattern and shaped capsulotomy that is based at least in part on the shape of an IOL and in particular an accommodating IOL.

摘要翻译： 提供了一种用于开发激光系统的系统，装置和方法，其可以产生精确的预定的拼图囊切术。 系统，装置和方法还提供可以使用单个激光器作为治疗激光器和激光雷达的激光系统，并且减少与用于进行撕囊术的手持设备相关的患者变异性和医生对医生的变异性， 囊切开术 还提供了至少部分地基于IOL的形状，特别是容纳IOL的精确的预定的拼图模式和形状的囊切开术。

公开(公告)号：US20100042079A1

公开(公告)日：2010-02-18

申请号：US12509454

申请日：2009-07-25

申请人： Rudolph W. Frey ,  Gary P. Gray

发明人： Rudolph W. Frey ,  Gary P. Gray

IPC分类号： A61B18/00 ,  A61B18/20 ,  G01R31/28

CPC分类号： A61B3/14 ,  A61F9/008 ,  A61F9/00825 ,  A61F2009/0087 ,  Y10T29/49004

摘要： There is provided a system, apparatus and methods for developing laser systems that can create a precise predetermined capsulotomy. The systems, apparatus and methods further provide laser systems that reduce the patient-to-patient variability and doctor-to-doctor variability associated with hand held apparatus for performing capsulorhexis and capsulotomies. There is further provided a precise predetermined shot pattern and shaped capsulotomy that is based at least in part on the shape of an IOL and in particular an accommodating IOL.

摘要翻译： 提供了一种用于开发激光系统的系统，装置和方法，其可以产生精确的预定囊切术。 系统，装置和方法进一步提供激光系统，其减少与用于进行撕囊术和囊切除术的手持装置相关的患者变异性和医生变异性。 还提供了至少部分地基于IOL的形状，特别是容纳IOL的精确的预定的射击模式和形状的囊切开术。

公开(公告)号：US06626896B2

公开(公告)日：2003-09-30

申请号：US09742884

申请日：2000-12-21

申请人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray ,  Neil Zepkin ,  George Richard Downes, Jr. ,  John E. McWhirter

发明人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray ,  Neil Zepkin ,  George Richard Downes, Jr. ,  John E. McWhirter

IPC分类号： A61F9007

CPC分类号： A61B3/113 ,  A61B2017/00694 ,  A61F9/008 ,  A61F9/00804 ,  A61F2009/00846 ,  A61F2009/00872 ,  A61F2009/00897

摘要： An ophthalmic laser system includes a laser beam delivery system and an eye tracker responsive to movement of the eye operable with a laser beam delivery system for ablating corneal material of the eye through placement of laser beam shot on a selected area of the cornea of the eye. The shots are fired in a sequence and pattern such that no laser shots are fired at consecutive locations and no consecutive shots overlap. The pattern is moved in response to the movement of the eye.

公开(公告)号：US06451008B1

公开(公告)日：2002-09-17

申请号：US09376133

申请日：1999-08-17

申请人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray ,  Neil Zepkin ,  George Richard Downes, Jr. ,  John E. McWhirter

发明人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray ,  Neil Zepkin ,  George Richard Downes, Jr. ,  John E. McWhirter

IPC分类号： A61B9018

CPC分类号： A61B3/113 ,  A61B2017/00694 ,  A61F9/008 ,  A61F9/00804 ,  A61F2009/00846 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A surface treatment laser beam delivery and tracking system is provided. The laser generates laser light along a original beam path at an energy level suitable for treating (e.g., eroding) a surface. An optical translator shifts the original beam path onto a resulting beam path. An optical angle adjuster changes the angle of the resulting beam path relative to the original beam path such that the laser light is incident on, and spatially distributed, the surface to be treated. A motion sensor transmits light energy to the surface and receives reflected light energy from the surface via the optical angle adjuster. The light energy transmitted by the motion sensor travels on a path that is parallel to the shifted beam as they travel through the optical angle adjuster. The reflected light energy is used by the motion sensor to detect movement of the surface relative to the original beam path and generate error control signals indicative of the movement. The optical angle adjuster is responsive to the error control signals to change the angle of the resulting beam path and the angle of the motion sensor's light energy in correspondence with one another. In this way, the beam originating from the treatment laser and the light energy originating from the motion sensor track together with the surface movement.

公开(公告)号：US06261220B1

公开(公告)日：2001-07-17

申请号：US09176544

申请日：1998-10-21

申请人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray

发明人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray

IPC分类号： A61F700

CPC分类号： A61F9/008 ,  A61F9/00804 ,  A61F2009/00855 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A method and system are provided for eroding or ablating a shaped volume of an eye's corneal tissue in accordance with the treatment of a specified eye condition. To determine the laser beam shot pattern, a plurality of laser beam shots of uniform intensity are first selected to form a uniform shot pattern of uniform shot density. The laser beam shots applied in accordance with the uniform shot pattern of uniform shot density would be capable of eroding a volume of the corneal tissue of uniform height. The volume of uniform height is approximately equivalent to that of the shaped volume. The laser beam shots are applied to the corneal tissue in a spatially distributed pattern spread over an area approximately equivalent to the surface area of the shaped volume to be eroded. The spatially distributed pattern extends the uniform shot pattern in fixed angles from a reference position on the shaped volume representative of the shaped volume's axis of symmetry. Shot density for the laser beam shots changes in correspondence with distance from the reference position.

摘要翻译： 提供了一种根据指定的眼睛状况的治疗来侵蚀或消融眼睛的角膜组织的成形体积的方法和系统。 为了确定激光射束图案，首先选择均匀强度的多个激光束照射以形成均匀射出密度的均匀射击图案。 根据均匀射击密度的均匀射击图案施加的激光束射击将能够侵蚀均匀高度的角膜组织的体积。 均匀高度的体积大约等于成形体积的体积。 将激光束拍摄以空间分布的图案施加到角膜组织上，该图案分布在大致等于待腐蚀的成形体积的表面积的区域上。 空间分布的图案以等于成形体积的对称轴的成形体积上的基准位置固定的角度延伸均匀的射出图案。 激光束照射的照射密度根据与参考位置的距离变化。

公开(公告)号：US5849006A

公开(公告)日：1998-12-15

申请号：US232956

申请日：1994-04-25

申请人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray

发明人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray

IPC分类号： A61B20060101 ,  A61B19/00 ,  A61F7/00 ,  A61F9/00 ,  A61F9/007 ,  A61F9/008 ,  A61F9/01 ,  A61N5/00 ,  A61N5/06 ,  B23K20060101 ,  B44B20060101 ,  H01S20060101

CPC分类号： A61F9/008 ,  A61F9/00804 ,  A61F2009/00855 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A method and system are provided for eroding or ablating a shaped volume of an eye's corneal tissue in accordance with the treatment of a specified eye condition. To determine the laser beam shot pattern, a plurality of laser beam shots of uniform intensity are first selected to form a uniform shot pattern of uniform shot density. The laser beam shots applied in accordance with the uniform shot pattern of uniform shot density would be capable of eroding a volume of the corneal tissue of uniform height. The volume of uniform height is approximately equivalent to that of the shaped volume. The laser beam shots are applied to the corneal tissue in a spatially distributed pattern spread over an area approximately equivalent to the surface area of the shaped volume to be eroded. The spatially distributed pattern extends the uniform shot pattern in fixed angles from a reference position on the shaped volume representative of the shaped volume's axis of symmetry. Shot density for the laser beam shots changes in correspondence with distance from the reference position.

摘要翻译： 提供了一种根据指定的眼睛状况的治疗来侵蚀或消融眼睛的角膜组织的成形体积的方法和系统。 为了确定激光射束图案，首先选择均匀强度的多个激光束照射以形成均匀射出密度的均匀射击图案。 根据均匀射击密度的均匀射击图案施加的激光束射击将能够侵蚀均匀高度的角膜组织的体积。 均匀高度的体积大约等于成形体积的体积。 将激光束拍摄以空间分布的图案施加到角膜组织上，该图案分布在大致等于待腐蚀的成形体积的表面积的区域上。 空间分布的图案以等于成形体积的对称轴的成形体积上的基准位置固定的角度延伸均匀的射出图案。 激光束照射的照射密度根据与参考位置的距离变化。

公开(公告)号：US5740803A

公开(公告)日：1998-04-21

申请号：US813079

申请日：1997-03-07

申请人： Gary P. Gray ,  Charline A. Gauthier ,  Ioannis G. Pallikaris

发明人： Gary P. Gray ,  Charline A. Gauthier ,  Ioannis G. Pallikaris

IPC分类号： A61B3/11 ,  A61B3/107

CPC分类号： A61B3/11

摘要： A method and system are provided for locating the center of the entrance pupil of an eye after the pupil thereof has been dilated. A first image of an eye is formed prior to pupil dilation. The center of the undilated pupil is referenced to a reference image of an anatomical landmark of the eye that appears in the first image. A second image of the eye is then formed when the pupil is dilated. When the reference image is positioned on an image of the anatomical landmark appearing in the second image, the center of the undilated pupil referenced to the reference image defines the center of the entrance pupil of the eye.

摘要翻译： 提供了一种方法和系统，用于在瞳孔扩张之后定位眼睛的入射光瞳的中心。 在瞳孔扩张之前形成眼睛的第一图像。 未扩张的瞳孔的中心参照出现在第一个图像中的眼睛的解剖学地标的参考图像。 然后当瞳孔扩大时，形成眼睛的第二个图像。 当参考图像位于出现在第二图像中的解剖标志的图像上时，参考参考图像的未折叠瞳孔的中心限定了眼睛的入射光瞳的中心。

公开(公告)号：US06679606B2

公开(公告)日：2004-01-20

申请号：US10338234

申请日：2003-01-08

申请人： John A. Campin ,  Gary P. Gray ,  George Pettit

发明人： John A. Campin ,  Gary P. Gray ,  George Pettit

IPC分类号： A61B310

CPC分类号： A61B3/1015 ,  A61B3/09

摘要： An automated, objective method for determining the accommodative range and aberration profile of an eye using a wavefront sensor that iteratively determines the change in accommodation of the lens of an eye.

摘要翻译： 一种用于使用波前传感器确定眼睛的调节范围和像差轮廓的自动客观方法，所述波前传感器迭代地确定眼睛的镜片的适应性的变化。

公开(公告)号：US06554429B1

公开(公告)日：2003-04-29

申请号：US09977538

申请日：2001-10-15

申请人： John A. Campin ,  Gary P. Gray ,  George Pettit

发明人： John A. Campin ,  Gary P. Gray ,  George Pettit

IPC分类号： A61B310

CPC分类号： A61B3/1015 ,  A61B3/09

摘要： An automated, objective method for determining the accommodative range and aberration profile of an eye using a wavefront sensor that iteratively determines the change in accommodation of the lens of an eye.

摘要翻译： 一种用于使用波前传感器确定眼睛的调节范围和像差轮廓的自动客观方法，所述波前传感器迭代地确定眼睛的镜片的适应性的变化。

公开(公告)号：US06394605B1

公开(公告)日：2002-05-28

申请号：US09863561

申请日：2001-05-23

申请人： John A. Campin ,  Gary P. Gray ,  George H. Pettit

发明人： John A. Campin ,  Gary P. Gray ,  George H. Pettit

IPC分类号： A61B300

CPC分类号： A61B3/14

摘要： An automated focusing method for a wavefront sensor that iteratively determines the best optics setting for the wavefront sensor by making objective measurements of the patient's focus without the need for subjective information from the patient.

摘要翻译： 一种用于波前传感器的自动对焦方法，其通过对患者的焦点进行客观测量来迭代地确定波前传感器的最佳光学设置，而不需要来自患者的主观信息。