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公开(公告)号：US20140171617A1
公开(公告)日：2014-06-19
申请号：US14237447
申请日：2012-08-08
申请人： Jay J. Farmer
发明人： Jay J. Farmer
CPC分类号： C07F15/065 , B01J31/1815 , B01J31/182 , B01J31/183 , B01J31/1835 , B01J31/2243 , B01J2231/14 , B01J2231/341 , B01J2531/0216 , B01J2531/0252 , B01J2531/31 , B01J2531/62 , B01J2531/845 , C07D307/33 , C08G64/34 , Y02P20/142
摘要： The present invention provides oligomeric metal complexes having more than one metal center and methods of using such complexes. The provided metal complexes are useful in the copolymerization of carbon dioxide and epoxides.
摘要翻译： 本发明提供具有多于一个金属中心的低聚金属络合物和使用这种络合物的方法。 所提供的金属络合物可用于二氧化碳和环氧化物的共聚。
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公开(公告)号：US20130197223A1
公开(公告)日：2013-08-01
申请号：US13825548
申请日：2011-09-22
申请人： Jay J. Farmer , Gabriel E. Job
发明人： Jay J. Farmer , Gabriel E. Job
IPC分类号： C07D487/04 , C07C221/00 , C07D493/08
CPC分类号： C07D493/08 , C07C221/00 , C07C223/02 , C07D221/00 , C07D487/04 , C07D519/00
摘要： Among other things, the present invention encompasses methods of synthesizing salicylaldehyde derivatives comprising the steps of: a) providing salicylaldehyde or a derivative thereof, b) forming an anhydro dimer of the provided salicylaldehyde compound, c) performing one or more chemical transformations on the anhydro dimer and d) hydrolyzing the anhydro dimer to provide a salicylaldehyde derivative different from that provided in step (a).
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公开(公告)号：US20120252747A1
公开(公告)日：2012-10-04
申请号：US13525900
申请日：2012-06-18
申请人： Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
发明人： Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
IPC分类号： A61K31/7056 , C07H17/08 , A61P1/14 , A61P31/00 , A61P29/00 , A61P35/00 , C07H17/00 , A61K31/706
摘要： The present invention provides macrocyclic compounds useful as therapeutic agents of the formula: or a pharmaceutically acceptable salt, ester, N-oxide, or prodrug thereof, wherein T, R1, R2, R3, D, E, F, and G are as defined herein. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory and prokinetic agents.
摘要翻译： 本发明提供可用作下式的治疗剂的大环化合物：或其药学上可接受的盐，酯，N-氧化物或前药，其中T，R 1，R 2，R 3，D，E，F和G如上所定义 这里。 更具体地，这些化合物可用作抗感染，抗增殖，抗炎和促动力剂。
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公开(公告)号：US08202843B2
公开(公告)日：2012-06-19
申请号：US10590782
申请日：2005-02-25
申请人： Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
发明人： Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
摘要： The present invention provides macrocyclic compounds useful as therapeutic agents of the formula: or a pharmaceutically acceptable salt, ester, N-oxide, or prodrug thereof, wherein T, R1, R2, R3, D, E, F, and G are as defined herein. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory and prokinetic agents.
摘要翻译： 本发明提供可用作下式的治疗剂的大环化合物：或其药学上可接受的盐，酯，N-氧化物或前药，其中T，R 1，R 2，R 3，D，E，F和G如上所定义 这里。 更具体地，这些化合物可用作抗感染，抗增殖，抗炎和促动力剂。
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35.发明授权公开(公告)号：US07335753B2
公开(公告)日：2008-02-26
申请号：US11359820
申请日：2006-02-21
申请人： Deping Wang , Joyce A. Sutcliffe , Adegboyega K. Oyelere , Timothy S. McConnell , Joseph A. Ippolito , John N. Abelson , Dane M. Springer , Joseph M. Salvino , Rongliang Lou , Joel A. Goldberg , Jay J. Farmer , Erin M. Duffy , Ashoke Bhattacharjee
发明人： Deping Wang , Joyce A. Sutcliffe , Adegboyega K. Oyelere , Timothy S. McConnell , Joseph A. Ippolito , John N. Abelson , Dane M. Springer , Joseph M. Salvino , Rongliang Lou , Joel A. Goldberg , Jay J. Farmer , Erin M. Duffy , Ashoke Bhattacharjee
IPC分类号： A61K31/7052 , A61K31/7048 , A61K31/4709 , A61K31/4176 , A61K31/4192 , A61K31/422 , C07H17/08 , C07D249/04 , C07D261/04 , C07D403/04 , C07D215/06
CPC分类号： A61K31/42 , A61K31/44 , A61K31/497 , A61K31/5375 , A61K31/7048 , C07H17/00
摘要： The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.
摘要翻译： 本发明提供了一种可用作抗感染，抗增殖，抗炎和促动力的双功能杂环化合物。 本发明还提供了制备双官能杂环化合物的方法，以及使用这些化合物作为抗感染剂，抗增殖剂，抗炎剂和/或促动力剂的方法。
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公开(公告)号：US06969726B2
公开(公告)日：2005-11-29
申请号：US10859476
申请日：2004-06-02
申请人： Rongliang Lou , Jiacheng Zhou , Ashoke Bhattacharjee , Shili Chen , Yi Chen , Jay J. Farmer , Joel A. Goldberg , Roger Hanselmann , Alia Orbin , Adegboyega K. Oyelere , Joseph M. Salvino , Dane M. Springer , Jennifer Tran , Deping Wang , Yusheng Wu
发明人： Rongliang Lou , Jiacheng Zhou , Ashoke Bhattacharjee , Shili Chen , Yi Chen , Jay J. Farmer , Joel A. Goldberg , Roger Hanselmann , Alia Orbin , Adegboyega K. Oyelere , Joseph M. Salvino , Dane M. Springer , Jennifer Tran , Deping Wang , Yusheng Wu
IPC分类号： A61K31/421 , A61K31/4439 , A61K31/497 , A61K31/501 , C07D255/02 , C07D257/04 , C07D263/20 , C07D263/32 , C07D263/38 , C07D403/10 , C07D413/02 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/10 , C07D417/12 , C07D417/14 , C07D453/02 , C07D473/00 , C07D487/04
CPC分类号： C07D487/04 , C07D263/20 , C07D263/24 , C07D263/26 , C07D263/32 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/10 , C07D417/12 , C07D417/14 , C07D453/02 , C07D471/04 , C07D473/00 , C07D473/34
摘要： The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.
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37.发明申请公开(公告)号：US20050197334A1
公开(公告)日：2005-09-08
申请号：US10671326
申请日：2003-09-25
申请人： Deping Wang , Joyce Sutcliffe , Adegboyega Oyelere , Timothy McConnell , Joseph Ippolito , John Abelson , Dane M. Springer , Joseph M. Salvino , Rongliang Lou , Joel A. Goldberg , Jay J. Farmer , Erin M. Duffy , Ashoke Bhattacharjee
发明人： Deping Wang , Joyce Sutcliffe , Adegboyega Oyelere , Timothy McConnell , Joseph Ippolito , John Abelson , Dane M. Springer , Joseph M. Salvino , Rongliang Lou , Joel A. Goldberg , Jay J. Farmer , Erin M. Duffy , Ashoke Bhattacharjee
IPC分类号： A61P31/04 , C07D413/02 , C07D417/02 , C07H17/00 , C07D43/02
CPC分类号： A61K31/42 , A61K31/44 , A61K31/497 , A61K31/5375 , A61K31/7048 , C07H17/00
摘要： The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.
摘要翻译： 本发明提供了一种可用作抗感染，抗增殖，抗炎和促动力的双功能杂环化合物。 本发明还提供了制备双官能杂环化合物的方法，以及使用这些化合物作为抗感染剂，抗增殖剂，抗炎剂和/或促动力剂的方法。
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