公开(公告)号：US20050077748A1

公开(公告)日：2005-04-14

申请号：US10930471

申请日：2004-08-31

申请人： Steven Brown ,  Guy Boitos ,  Brett Woodson ,  Jay Ennis ,  Brandon Ye

发明人： Steven Brown ,  Guy Boitos ,  Brett Woodson ,  Jay Ennis ,  Brandon Ye

IPC分类号： B60R5/04 ,  B62D43/10 ,  B60P7/02

CPC分类号： B62D43/10 ,  B60R5/04

摘要： A storage system (14) of a motor vehicle (10) presenting a cargo space defining an opening (18) for storing spare tires, tools, and the like. A load floor assembly (22) is configured to cover the opening (18) and to support various loads (41) positioned thereon. A cover (24) of the load floor assembly (22) is molded from a polystyrene or other foam composite. At least one laminate (18), formed from a hard board or other sheet material, is adhered to the cover (24). A support frame (40), formed from a foamed polypropylene, includes a density greater than the density of the cover (24) and therefore has a higher mass to provide a significant amount of structural benefits to the load floor assembly (22) for supporting and preventing a deflection of the cover (24) under the force of the loads (41) applied thereto.

摘要翻译： 机动车辆（10）的存储系统（14）具有限定用于存储备用轮胎，工具等的开口（18）的货物空间。 负载地板组件（22）构造成覆盖开口（18）并且支撑位于其上的各种负载（41）。 载荷地板组件（22）的盖（24）由聚苯乙烯或其它泡沫复合材料模制。 由硬板或其他片状材料形成的至少一个层压体（18）粘附到盖（24）上。 由发泡聚丙烯形成的支撑框架（40）包括大于盖（24）的密度的密度，因此具有更高的质量，以向承载地板组件（22）提供大量的结构益处，用于支撑 并且防止在施加到其上的负载（41）的力下盖（24）的偏转。

公开(公告)号：US06784832B2

公开(公告)日：2004-08-31

申请号：US10656361

申请日：2003-09-05

申请人： Ronald P. Knockeart ,  Bob Drury ,  Melvin A. Rode ,  Steven Brown ,  Harry Asher ,  Paul A. Jozefowicz

发明人： Ronald P. Knockeart ,  Bob Drury ,  Melvin A. Rode ,  Steven Brown ,  Harry Asher ,  Paul A. Jozefowicz

IPC分类号： G01S502

CPC分类号： G08G1/096811 ,  G01C21/3415 ,  G01C21/3492 ,  G08G1/096838 ,  G08G1/096844 ,  G08G1/096861 ,  G08G1/096872 ,  G08G1/096883

摘要： A vehicle information system which includes an in-vehicle system 105 and a centralized server system 120. The in-vehicle system communicates with the server system using a wireless communication link 110, such as over a cellular telephone system. A position system, such as a set of GPS satellites 140, provides positioning signals that are used by the in-vehicle systems, and optionally by the centralized server system to increase the accuracy of position estimates. In one version of the system, an operator specifies a destination to an in-vehicle system which validates the destination. The in-vehicle system transmits specification of the destination to a server system 125 at the centralized server. The server system computes a route to the destination and transmits the computed route to the in-vehicle system. The in-vehicle system guides the operator along the route. If the in-vehicle system detects that the vehicle has deviated from the planned route, it replans a new route to the destination using an in-vehicle map database.

公开(公告)号：US06707421B1

公开(公告)日：2004-03-16

申请号：US09252432

申请日：1999-02-18

申请人： Bob Drury ,  Ronald P. Knockeart ,  Melvin A. Rode ,  Steven Brown ,  Harry Asher

发明人： Bob Drury ,  Ronald P. Knockeart ,  Melvin A. Rode ,  Steven Brown ,  Harry Asher

IPC分类号： G01S502

CPC分类号： G08G1/096811 ,  G01C21/34 ,  G01C21/3415 ,  G01C21/3461 ,  G01C21/3476 ,  G01C21/3484 ,  G01C21/3492 ,  G01C21/3617 ,  G01C21/3679 ,  G01C21/3688 ,  G01C21/3691 ,  G08G1/096827 ,  G08G1/096838 ,  G08G1/096844 ,  G08G1/096861 ,  G08G1/096872 ,  G08G1/096883 ,  G08G1/0969

摘要： An information system for providing services including traffic and navigation services, as well as other information services to a driver. One versions of the system makes use of existing components of a wireless telephone system, for example, by using the input and output capabilities of a telephone handset. Another version is a portable system that includes multiple switches for initiating access to a remote server in one of a number of operating modes. For instance the system has switches for initiating traffic information, roadside assistance, personal information, or emergency modes. The system includes a positioning system for generating position data related to a geographic location of the system, and a wireless communication device. The system also includes an audio output device, such as a speaker for presenting the received information. The system can also include a storage for a unique identification of the information system. This identification is passed to the remote server through the wireless communication device. Another version of the system provides both autonomous and client-server based navigation services in which a removable database supports route planning in a limited area and a remote server supports route planning outside that area.

公开(公告)号：US06664924B2

公开(公告)日：2003-12-16

申请号：US10246885

申请日：2002-09-19

申请人： Ronald P. Knockeart ,  Bob Drury ,  Melvin A. Rode ,  Steven Brown ,  Harry Asher ,  Paul A. Jozefowicz

发明人： Ronald P. Knockeart ,  Bob Drury ,  Melvin A. Rode ,  Steven Brown ,  Harry Asher ,  Paul A. Jozefowicz

IPC分类号： H04B7185

CPC分类号： G08G1/096811 ,  G01C21/3415 ,  G01C21/3492 ,  G08G1/096838 ,  G08G1/096844 ,  G08G1/096861 ,  G08G1/096872 ,  G08G1/096883

摘要： A vehicle information system which includes an in-vehicle system 105 and a centralized server system 120. The in-vehicle system communicates with the server system using a wireless communication link 110, such as over a cellular telephone system. A position system, such as a set of GPS satellites 140, provides positioning signals that are used by the in-vehicle systems, and optionally by the centralized server system to increase the accuracy of position estimates. In one version of the system, an operator specifies a destination to an in-vehicle system which validates the destination. The in-vehicle system transmits specification of the destination to a server system 125 at the centralized server. The server system computes a route to the destination and transmits the computed route to the in-vehicle system. The in-vehicle system guides the operator along the route. If the in-vehicle system detects that the vehicle has deviated from the planned route, it replans a new route to the destination using an in-vehicle map database.

公开(公告)号：US11454196B1

公开(公告)日：2022-09-27

申请号：US12150765

申请日：2008-04-30

申请人： Steven Brown

发明人： Steven Brown

IPC分类号： F02M21/04 ,  F02M21/02

摘要： A fuel bowl is disclosed. The fuel bowl comprises a body having an interior opposite an exterior, four sides, and a bottom opposite an opening. The opening is configured to be in fluid communication with a carburetor or an adaptor. The fuel bowl also comprises a fuel inlet port disposed in at least one of the four sides and configured to receive a gaseous fuel from a fuel regulator. The gaseous fuel expands and contracts within the body. A carburetor system is also disclosed. The carburetor system comprises a gaseous fuel, a fuel regulator configured to receive and deliver the gaseous fuel, a fuel bowl in fluid communication with the fuel regulator and a carburetor, a final fuel metering restriction disposed in an inlet supply port of a cylinder of the carburetor, and a venturi disposed in the carburetor.

公开(公告)号：US11289179B1

公开(公告)日：2022-03-29

申请号：US15428999

申请日：2017-02-09

申请人： Steven Brown ,  Steven Dickerson

发明人： Steven Brown ,  Steven Dickerson

IPC分类号： G16H20/10

摘要： Provided is a system providing a solution for improving prescription drug compliance monitoring and compliance. Prescription drug compliance monitoring may be achieved by using patient's electronic device to initiate secure digital imaging. Medications may be dispensed in containers with pre-printed encoded unique identifiers and markings. The patient may use the digital camera in their smart phone to take a picture of the dispensed blister pack which may be processed and analyzed. Analysis may include assessment of the number of pills taken from and remaining in the uniquely identified blister pack. Package identification and consumption information may then be linked with other prescription information to determine if the observed rate of use is compliant with the legal prescription and to document that the imaged medication package is the same as the dispensed medication package. Data may also be linked with pharmacologic and clinical data to categorize risk and urgency of misuse.

公开(公告)号：US08858600B2

公开(公告)日：2014-10-14

申请号：US12103576

申请日：2008-04-15

申请人： Steven Brown ,  Manoj Krishna ,  Tai Friesem ,  Jose Fernandez

发明人： Steven Brown ,  Manoj Krishna ,  Tai Friesem ,  Jose Fernandez

IPC分类号： A61B17/70 ,  A61F2/44

CPC分类号： A61B17/7023 ,  A61B17/7001 ,  A61B17/7004 ,  A61B17/7014 ,  A61B17/7025 ,  A61B17/7032 ,  A61B17/7041 ,  A61B17/7049 ,  A61B17/7064 ,  A61F2/442

摘要： The present invention provides a dynamic stabilization device positionable about a portion of a spinal column. The stabilization device may generally include a first component and a second component, where the first and second components are movably coupled to one another to define an arcuate path of motion. The stabilization device may also include one or more adjustment elements positionable within first and second adjustment openings to affect the path of motion between the first and second components and/or the behavior and characteristics of the movement. In addition, one or more resistive elements may be adjustably positionable within either and/or both of the first and second adjustment openings to provide resistance and/or dampening of the forces experienced as the first and second components move relative to one another. The stabilization device may further define a joint having three degrees of freedom to adapt to movement of a spinal column.

摘要翻译： 本发明提供了可围绕脊柱的一部分定位的动态稳定装置。 稳定装置通常可以包括第一部件和第二部件，其中第一和第二部件彼此可移动地联接以限定弓形运动路径。 稳定装置还可以包括可定位在第一和第二调节开口内的一个或多个调节元件，以影响第一和第二部件之间的运动路径和/或运动的行为和特征。 此外，一个或多个电阻元件可以可调节地定位在第一和第二调节开口内和/或两者中，以提供当第一和第二部件相对于彼此移动时所经受的力的电阻和/或阻尼。 稳定装置还可以限定具有三个自由度以适应脊柱的运动的关节。

公开(公告)号：US08796318B2

公开(公告)日：2014-08-05

申请号：US12465767

申请日：2009-05-14

申请人： Edward Roberts ,  Hugh Rosen ,  Steven Brown ,  Miguel A. Guerrero ,  Xuemei Peng ,  Ramulu Poddutoori

发明人： Edward Roberts ,  Hugh Rosen ,  Steven Brown ,  Miguel A. Guerrero ,  Xuemei Peng ,  Ramulu Poddutoori

IPC分类号： A61K31/4245 ,  C07D271/06

CPC分类号： C07D271/06 ,  A61K31/4245 ,  C07D263/32 ,  C07D401/04 ,  C07D413/04 ,  C07D413/14 ,  C07D471/04

摘要： Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.

摘要翻译： 提供激活亚型1的鞘氨醇-1-磷酸受体的化合物。 某些化合物选择性地激活了关于鞘氨醇 - 1-磷酸受体亚型3的受体亚型1。本发明化合物的用途和方法用于治疗病症，其中在医学上指示S1P1的活化，激动，抑制或拮抗作用。

公开(公告)号：US08629255B2

公开(公告)日：2014-01-14

申请号：US13112641

申请日：2011-05-20

申请人： Steven Brown ,  Adam Guss ,  Shihui Yang ,  Tatiana Karpinets ,  Lee Lynd ,  Xiongjun Shao

发明人： Steven Brown ,  Adam Guss ,  Shihui Yang ,  Tatiana Karpinets ,  Lee Lynd ,  Xiongjun Shao

IPC分类号： C07H21/00 ,  C12P7/02 ,  C12N1/00 ,  C12N15/75 ,  C12N1/15

CPC分类号： C12N9/0006 ,  C12P7/10 ,  Y02E50/16

摘要： The present invention provides isolated nucleic acid molecules which encode a mutant acetaldehyde-CoA/alcohol dehydrogenase or mutant alcohol dehydrogenase and confer enhanced tolerance to ethanol. The invention also provides related expression vectors, genetically engineered microorganisms having enhanced tolerance to ethanol, as well as methods of making and using such genetically modified microorganisms for production of biofuels based on fermentation of biomass materials.

摘要翻译： 本发明提供了分离的核酸分子，其编码突变乙醛-CoA /醇脱氢酶或突变型醇脱氢酶并赋予对乙醇增强的耐受性。 本发明还提供相关表达载体，具有增强的对乙醇的耐受性的遗传工程微生物，以及基于生物质材料的发酵制备和使用这些基因修饰的微生物生产生物燃料的方法。

公开(公告)号：US20120329840A1

公开(公告)日：2012-12-27

申请号：US13605561

申请日：2012-09-06

申请人： Edward Roberts ,  Hugh Rose ,  Steven Brown ,  Miguel A. Guerrero ,  Xuemei Peng ,  Ramulu Poddutoori

发明人： Edward Roberts ,  Hugh Rose ,  Steven Brown ,  Miguel A. Guerrero ,  Xuemei Peng ,  Ramulu Poddutoori

IPC分类号： A61K31/4245 ,  A61P11/00 ,  A61P37/06 ,  C07D271/06 ,  A61P25/00

CPC分类号： C07D271/06 ,  A61K31/4245 ,  C07D263/32 ,  C07D401/04 ,  C07D413/04 ,  C07D413/14 ,  C07D471/04

摘要： Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.