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公开(公告)号：US20100158983A1
公开(公告)日：2010-06-24
申请号：US12162667
申请日：2007-02-07
Applicant: Thomas A. Davis , Walker M. Rast
Inventor： Thomas A. Davis , Walker M. Rast
CPC classification number: B01D71/82 , B01D67/009 , B01D67/0093 , B01D71/36 , B01D2323/34 , B01D2325/14 , C08J5/2293 , C08J7/123 , C08J2327/18 , Y10T442/2139
Abstract: Polymer membranes are disclosed having increased permeability. The process of the present disclosure, for instance, can increase the ion permeability of membranes and/or the gas permeability of membranes. In one embodiment, for instance, a precursor polymer is subjected to energy in an amount sufficient to form damage tracks through the thickness of the polymer. The damage tracks are then oxidized to form free radical groups. The precursor polymer is then hydrolyzed causing ion groups to form that cluster along the damage tracks. In one embodiment, sulfonated tetrafluoroethylene-based copolymer ionomer membranes are formed that have increased conductivity. Other ionomer membranes that may be formed according to the present disclosure include copolymers of a vinyl hydrocarbon and a vinyl carboxylic acid.
Abstract translation: 公开了具有增加的渗透性的聚合物膜。 例如，本公开的方法可以增加膜的离子渗透性和/或膜的气体渗透性。 在一个实施方案中，例如，前体聚合物经受足够的能量以形成通过聚合物厚度的损伤轨迹。 损伤轨迹然后氧化形成自由基。 然后将前体聚合物水解，导致离子基团沿着损伤轨道形成该簇。 在一个实施方案中，形成具有增加的导电性的磺化四氟乙烯基共聚物离聚物膜。 根据本公开可以形成的其它离聚物膜包括乙烯基烃和乙烯基羧酸的共聚物。
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公开(公告)号：US20100116663A1
公开(公告)日：2010-05-13
申请号：US12617250
申请日：2009-11-12
Applicant: Thomas A. Davis
Inventor： Thomas A. Davis
CPC classification number: B01D61/44 , B01D61/025 , B01D2311/2623 , Y10T428/31504 , Y10T428/31725
Abstract: Methods, systems and compositions for recovery of regenerant ions from spent regenerant solution by utilization of electrodialysis are provided. For example, in certain aspects methods for separating spent regenerant using an electrodialysis system comprising selective membranes are described. Furthermore, the invention provides methods for treating a friable solid ion-removal material to prevent fragmentation during regeneration.
Abstract translation: 提供了通过利用电渗析从废再生剂溶液回收再生子离子的方法，系统和组合物。 例如，在某些方面，描述了使用包含选择性膜的电渗析系统分离废再生剂的方法。 此外，本发明提供了用于处理易碎的固体离子去除材料以防止再生期间的碎裂的方法。
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公开(公告)号：US20080124396A1
公开(公告)日：2008-05-29
申请号：US11932737
申请日：2007-10-31
Applicant: Alexander Schwarz , Guerard W. Byrne , Thomas A. Davis , Lisa E. Diamond , John S. Logan
Inventor： Alexander Schwarz , Guerard W. Byrne , Thomas A. Davis , Lisa E. Diamond , John S. Logan
IPC: A61K47/32 , A61P37/06 , A61K9/00 , A61K38/19 , A61K39/395
CPC classification number: C07K16/00 , A61K39/001 , A61K47/59 , A61K47/60 , A61K47/61 , A61K47/645 , A61K2039/6093
Abstract: One aspect of the present invention relates to methods and compositions for attenuating xenograft rejection by administering, to an animal receiving the xenograft, an amount of a polymer-derivatized xenoantigen (hereinafter “xenopolymer”) effective for inhibiting or lessening the severity of hyperacute rejection response (HAR), or other immunological response to the graft, that is dependent on the presence of the xenoantigen on the grafted tissues or cells. In certain embodiments, the xenopolymer is administered in an amount sufficient to neutralize host antibodies (“xenoreactive antibodies” or “XNA”) immunoreactive with the xenoantigen. The xenopolymer may additionally, or alternatively, be used as a tolerogen (or anergen) for the xenoantigen, e.g., able to suppress, to some degree, the production/secretion of XNAs by the immune system of the host.
Abstract translation: 本发明的一个方面涉及通过向接受异种移植物的动物施用一定量的有效抑制或减轻超急性排斥反应严重性的聚合物衍生的异种抗原（以下称为“异戊烯”）来减弱异种移植排斥的方法和组合物 （HAR）或其他对移植物的免疫应答，这取决于移植组织或细胞上异种抗原的存在。 在某些实施方案中，以足以中和与异种抗原免疫反应的宿主抗体（“异反应性抗体”或“XNA”）的量施用异种聚合物。 异源聚合物可以另外地或替代地用作异种抗原的耐受原（或过敏原），例如能够在一定程度上抑制宿主的免疫系统产生/分泌XNA。
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公开(公告)号：US07083730B2
公开(公告)日：2006-08-01
申请号：US10632369
申请日：2003-08-01
Applicant: Thomas A. Davis
Inventor： Thomas A. Davis
CPC classification number: C02F1/441 , B01D61/025 , B01D61/027 , B01D61/422 , B01D61/44 , B01D61/52 , B01D61/58 , C02F1/048 , C02F1/442 , C02F1/444 , C02F1/469 , C02F1/4693 , C02F9/00 , C02F2103/08 , C02F2201/46115 , Y02A20/128 , Y02A20/131 , Y02A20/134 , Y02W10/37
Abstract: Sodium chloride and purified water are recovered by treating salt water that contains sodium chloride with an integrated reverse osmosis and electrodialysis system, which includes an efficiency-enhancing feature that is one or more of the following: the use of univalent anion and univalent cation selective membranes in the electrodialysis unit; the addition of a nanofiltration unit to process the diluate from the electrodialysis unit; or operation of the electrodialysis unit at an elevated pressure. Magnesium and bromine can optionally be produced when the salt water contains these materials.
Abstract translation: 通过用集成的反渗透和电渗析系统处理含有氯化钠的盐水来回收氯化钠和净化水，其包括以下一个或多个的效率增强特征：使用一价阴离子和一价阳离子选择膜 在电渗析装置中; 加入纳滤单元以处理来自电渗析单元的稀释液; 或在升高的压力下操作电渗析装置。 当盐水含有这些材料时，可以任选地生产镁和溴。
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Patent Agency Ranking
公开(公告)号：US5583551A
公开(公告)日：1996-12-10
申请号：US434903
申请日：1995-05-01
Applicant: Donald R. Allred , Thomas A. Davis
Inventor： Donald R. Allred , Thomas A. Davis
CPC classification number: B41J2/09
Abstract: A deflection electrode for use in a continuous ink jet printing device molded of powdered ultra high molecular weight polyethylene combined with carbon black and subjected to oxygen plasma treatment.
Abstract translation: 一种用于连续喷墨打印装置的偏转电极，其由粉末状超高分子量聚乙烯与炭黑组合并进行氧等离子体处理。
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公开(公告)号：US4390521A
公开(公告)日：1983-06-28
申请号：US139479
申请日：1980-04-11
Applicant: Thomas A. Davis , William J. Asher
Inventor： Thomas A. Davis , William J. Asher
IPC: A61K38/16 , A61K9/107 , A61K9/50 , A61K35/18 , A61K38/00 , A61M1/36 , C07K14/805 , A01N25/28 , A61K9/64 , B01J13/02
CPC classification number: A61K35/18 , A61K9/5068 , C07K14/805 , A61K38/00 , A61M1/3693 , A61M2202/0433 , Y10T428/2984
Abstract: Artificial red cells have been prepared which comprise microdroplets of stroma-free, aqueous hemoglobin solution encapsulated in polymerized hemoglobin membranes which ae permeable to oxygen and impermeable to hemoglobin. These artificial red cells can be made having diameters generally less than four microns are able to maintain their individual integrity under conditions of flow with shear rates of up to about 2.times.10.sup.5 sec.sup.-1.
Abstract translation: 已经制备人造红细胞，其包含无基质的含水血红蛋白溶液的微滴，该溶液包封在聚合血红蛋白膜中，其可透氧并且不可渗透血红蛋白。 这些人造红细胞可以制成直径通常小于4微米，能够在剪切速率高达约2×105秒-1的流动条件下保持其个体完整性。
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公开(公告)号：US4376059A
公开(公告)日：1983-03-08
申请号：US139454
申请日：1980-04-11
Applicant: Thomas A. Davis , William J. Asher
Inventor： Thomas A. Davis , William J. Asher
IPC: A61K38/16 , A61K9/107 , A61K9/50 , A61K35/18 , A61K38/00 , A61P7/08 , C07K14/805 , B01J13/02 , A01N25/28 , A61K9/64
CPC classification number: C07K14/805 , A61K35/18 , A61K9/5068 , A61K38/00 , Y10T436/101666
Abstract: A process for preparing artificial red cells comprising microdroplets of aqueous, stroma-free hemoglobin solution encapsulated in membranes of polymerized hemoglobin, said process comprising forming microdroplets of hemoglobin solution in a continuous oil phase, cross-linking the hemoglobin at the surface of the microdroplets with a suitable cross-linking agent to form the artificial red cells and recovering the cells. In one embodiment, a liquid membrane encapsulation technique employing a water-soluble cross-linking agent is used to form the cells. In another embodiment an oil-soluble cross-linking agent is present in the oil phase containing the hemoglobin microdroplets.
Abstract translation: 一种制备人造红细胞的方法，包括包封在聚合血红蛋白的膜中的含水基质的血红蛋白溶液的微滴，所述方法包括在连续油相中形成血红蛋白溶液的微滴，将微滴表面的血红蛋白与 合适的交联剂以形成人造红细胞并回收细胞。 在一个实施方案中，使用采用水溶性交联剂的液膜封装技术来形成细胞。 在另一个实施方案中，油溶性交联剂存在于含有血红蛋白微滴的油相中。
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公开(公告)号：US4327046A
公开(公告)日：1982-04-27
申请号：US101511
申请日：1979-12-07
Applicant: Thomas A. Davis , Donald R. Cowsar
Inventor： Thomas A. Davis , Donald R. Cowsar
IPC: A61G5/02 , A47C7/00 , A47C7/46 , A61F5/01 , A61G5/00 , B29C44/12 , B29C67/20 , B65D81/02 , C09J163/00 , B29J1/00 , B29C1/02 , B29D27/00
CPC classification number: B29C67/207 , A47C27/086 , A61F5/01 , B29C44/1204 , B29L2031/753 , B29L2031/771 , Y10S264/07 , Y10S5/913 , Y10T428/233 , Y10T428/239 , Y10T428/249953 , Y10T428/249985 , Y10T428/249992 , Y10T428/25 , Y10T428/254
Abstract: A rigid, shaped, mass support system, such as support or seating appliances for disabled or handicapped persons, is provided by charging a flexible container (2) made of elastic polymeric film with a uniform mixture of rigid particles of a mesh size relatively small compared to the size of the system and a curable adhesive polymeric binder material. The charged container (2) and its contents are molded to adapt to or fit the shape of the mass, such as the contour of that portion of the body to be supported, and evacuated to remove volatiles and fix the shape of the contents of the container. The adhesive binder is then cured to solidify the molded contents of the container to form a composite, from which the polymeric film can be stripped away, after which an adhesive paint is applied to seal and protect the surface.
Abstract translation: 通过将由弹性聚合物膜制成的柔性容器（2）与网格尺寸相对较小的刚性颗粒的均匀混合物相比较，来提供用于残疾人或残疾人的支撑或座椅装置的刚性，成形的质量支撑系统 到系统的尺寸和可固化的粘合剂聚合物粘合剂材料。 被充填的容器（2）及其内容物被模制以适应或适配质量的形状，例如待支撑的身体的那部分的轮廓，并抽真空以除去挥发物并固定其中的内容物的形状 容器。 然后将粘合剂粘合剂固化以固化容器的模制内容物以形成复合材料，从中可以剥离聚合物膜，之后施加粘合剂涂料以密封和保护表面。
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公开(公告)号：US4300537A
公开(公告)日：1981-11-17
申请号：US188705
申请日：1980-09-19
Applicant: Thomas A. Davis
Inventor： Thomas A. Davis
Abstract: A solar collector mounting system includes a vertically extending pedestal for supporting a solar collector at a predetermined minimum height above ground level to provide an unobstructed utilization of the space immediately surrounding the pedestal. The pedestal includes a pivoting bracket at the upper end for supporting an array of panels for orientation into the sun, and is formed of a hollow structure to define a liquid storage reservoir for storing a heated liquid.
Abstract translation: 太阳能收集器安装系统包括垂直延伸的基座，用于在地平面以上的预定最小高度处支撑太阳能收集器，以提供立即围绕基座的空间的无障碍地利用。 基座包括在上端的枢转托架，用于支撑用于定向到太阳的面板阵列，并且由中空结构形成以限定用于储存加热液体的液体储存容器。
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