Ion source for mass spectrometer and method of producing analyte ion stream
    33.
    发明授权
    Ion source for mass spectrometer and method of producing analyte ion stream 有权
    用于质谱的离子源和产生分析物离子流的方法

    公开(公告)号:US09305761B2

    公开(公告)日:2016-04-05

    申请号:US14458311

    申请日:2014-08-13

    CPC classification number: H01J49/16 H01J49/0454

    Abstract: An ion source for a mass spectrometer and a method of ionizing a sample are disclosed. A droplet generator is configured to emit a stream of analyte droplets, which are ionized upon impact with a target, thus forming an ion stream. Preferably, the droplets have a diameter that is greater than a preset value to increase the kinetic energy of the droplets. Additionally, the droplet generator can be configured to create a gas flow that increases the kinetic energy of the droplets. In one embodiment, the target is positioned upstream of an inlet of a mass spectrometer so that the ion stream enters the inlet. In another preferred embodiment, the target is positioned downstream of the inlet so that the stream of droplets passes through the inlet of the mass spectrometer, and the inlet is provided with a pressure drop that increases the kinetic energy of the droplets.

    Abstract translation: 公开了用于质谱仪的离子源和离子化样品的方法。 液滴发生器被配置为发射分析物液滴流,其在与靶碰撞时被离子化,从而形成离子流。 优选地,液滴具有大于预设值的直径以增加液滴的动能。 另外,液滴发生器可以被配置成产生增加液滴动能的气流。 在一个实施方案中,靶位于质谱仪的入口的上游,使得离子流进入入口。 在另一个优选实施例中,靶位于入口的下游,使得液滴流通过质谱仪的入口,并且入口设置有增加液滴的动能的压降。

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