Dynamically variable separation among nanoparticles for nano-enhanced Raman spectroscopy (NERS) molecular sensing
    31.
    发明授权
    Dynamically variable separation among nanoparticles for nano-enhanced Raman spectroscopy (NERS) molecular sensing 有权
    用于纳米增强拉曼光谱(NERS)分子感测的纳米颗粒之间的动态变化分离

    公开(公告)号:US07342656B2

    公开(公告)日:2008-03-11

    申请号:US11252134

    申请日:2005-10-17

    IPC分类号: G01J3/44 G01N21/65

    CPC分类号: G01N21/658

    摘要: A NERS-active structure includes a deformable, active nanoparticle support structure for supporting a first nanoparticle and a second nanoparticle that is disposed proximate the first nanoparticle. The nanoparticles each comprise a NERS-active material. The deformable, active nanoparticle support structure is configured to vary the distance between the first nanoparticle and the second nanoparticle while performing NERS. Various active nanoparticle support structures are disclosed. A NERS system includes such a NERS-active structure, a radiation source for generating radiation scatterable by an analyte located proximate the NERS-active structure, and a radiation detector for detecting Raman scattered radiation scattered by the analyte. A method for performing NERS includes providing such a NERS-active structure, providing an analyte at a location proximate the NERS-active structure, irradiating the NERS-active structure and the analyte with radiation, varying the distance between the nanoparticles, and detecting Raman scattered radiation scattered by the analyte.

    摘要翻译: NERS活性结构包括用于支撑第一纳米颗粒的可变形的活性纳米颗粒支撑结构和邻近第一纳米颗粒设置的第二纳米颗粒。 纳米颗粒各自包含NERS-活性材料。 可变形的活性纳米颗粒支撑结构被配置为在执行NERS的同时改变第一纳米颗粒和第二纳米颗粒之间的距离。 公开了各种活性纳米颗粒载体结构。 NERS系统包括这样的NERS-活性结构,用于产生由位于NERS-活性结构附近的分析物可散射的辐射的辐射源,以及用于检测被分析物散射的拉曼散射辐射的辐射检测器。 执行NERS的方法包括提供这样的NERS活性结构,在靠近NERS-活性结构的位置提供分析物,用辐射照射NERS-活性结构和分析物,改变纳米颗粒之间的距离并检测拉曼散射 被分析物散射的辐射。

    DOUBLE-GRATING SURFACE-ENHANCED RAMAN SPECTROSCOPY
    33.
    发明申请
    DOUBLE-GRATING SURFACE-ENHANCED RAMAN SPECTROSCOPY 有权
    双光泽表面增强拉曼光谱

    公开(公告)号:US20140375990A1

    公开(公告)日:2014-12-25

    申请号:US14381009

    申请日:2012-03-06

    IPC分类号: G01J3/02 G01J3/44 G01N21/65

    摘要: A double-grating surface-enhanced Raman spectrometer. The spectrometer includes a substrate; a plurality of nanofingers carried by the substrate, the nanofingers arranged to define a first optical grating; a light source oriented to project a beam of light toward the first optical grating; a second optical grating oriented to receive a beam of light scattered from the first optical grating; and a detector oriented to receive a beam of light scattered from the second optical grating.

    摘要翻译: 双光栅表面增强拉曼光谱仪。 光谱仪包括基片; 由衬底承载的多个纳米装置,所述纳米装置布置成限定第一光栅; 光源,其朝向所述第一光栅投影光束; 第二光栅,其被定向为接收从第一光栅散射的光束; 以及用于接收从第二光栅散射的光束的检测器。

    Enhancing signals in Surface Enhanced Raman Spectroscopy (SERS)
    35.
    发明授权
    Enhancing signals in Surface Enhanced Raman Spectroscopy (SERS) 有权
    增强表面增强拉曼光谱(SERS)信号

    公开(公告)号:US08358407B2

    公开(公告)日:2013-01-22

    申请号:US12771753

    申请日:2010-04-30

    IPC分类号: G01J3/40

    CPC分类号: G01N21/658 B82Y15/00

    摘要: An integrated device for enhancing signals in Surface Enhanced Raman Spectroscopy (SERS). The integrated device comprising an array of nanostructures comprising a material, wherein the material is configured to allow light to pass through. The integrated device also comprising SERS active nanoparticles disposed on at least portion of the array of nanostructures and a mirror integrated below a base of the array of nanostructures. The mirror is configured to reflect light passing through the material into the array of nanostructures.

    摘要翻译: 一种用于增强表面增强拉曼光谱(SERS)信号的集成器件。 所述集成器件包括纳米结构的阵列,其包括材料,其中所述材料被配置为允许光通过。 该集成装置还包括设置在纳米结构阵列的至少一部分上的SERS活性纳米颗粒和集成在纳米结构阵列的基底下方的反射镜。 镜子被配置为将通过材料的光反射到纳米结构阵列中。

    Compact sensor system
    36.
    发明授权
    Compact sensor system 有权
    紧凑型传感器系统

    公开(公告)号:US08319963B2

    公开(公告)日:2012-11-27

    申请号:US12772063

    申请日:2010-04-30

    IPC分类号: G01J3/44

    CPC分类号: G01N21/658 G01N21/7746

    摘要: A compact sensor system comprising: an analysis cell configured for photon-matter interaction, where photons are received from a light source; and an integrated-optical spectral analyzer configured for identifying a set of frequencies, the integrated-optical spectral analyzer comprising: a waveguide coupled with the analysis cell, the waveguide configured for propagating a set of frequencies through the waveguide; one or more ring resonators coupled with the waveguide, the one or more ring resonators comprising a predetermined bandwidth and configured for capturing the set of frequencies corresponding to frequencies within the predetermined bandwidth; and one or more frequency detectors coupled with the one or more tunable ring resonators, the one or more frequency detectors configured for generating electrical signals that identify each of the set of frequencies.

    摘要翻译: 一种紧凑的传感器系统,包括:配置用于光子 - 物质相互作用的分析单元,其中从光源接收光子; 所述集成光谱分析仪包括:与所述分析单元耦合的波导,所述波导被配置为通过所述波导传播一组频率;以及波导,其被配置为用于识别一组频率。 一个或多个与所述波导耦合的环形谐振器,所述一个或多个环形谐振器包括预定带宽并被配置用于捕获与所述预定带宽内的频率相对应的频率集合; 以及与所述一个或多个可调环形谐振器耦合的一个或多个频率检测器,所述一个或多个频率检测器被配置用于产生标识所述一组频率中的每一个的电信号。

    TUNABLE APPARATUS FOR PERFORMING SERS
    37.
    发明申请
    TUNABLE APPARATUS FOR PERFORMING SERS 有权
    用于执行人员的装置

    公开(公告)号:US20110267608A1

    公开(公告)日:2011-11-03

    申请号:US12771779

    申请日:2010-04-30

    IPC分类号: G01J3/44

    CPC分类号: G01N21/658

    摘要: A tunable apparatus for performing Surface Enhanced Raman Spectroscopy (SERS) includes a deformable layer and a plurality of SERS-active nanoparticles disposed at one or more locations on the deformable layer, wherein the one or more locations are configured to be illuminated with light of a pump wavelength to cause Raman excitation light to interact with the nanoparticles and produce enhanced Raman scattered light from molecules located in close proximity to the nanoparticles. In addition, a morphology of the deformable layer is configured to be controllably varied to modify an intensity of the Raman scattered light produced from the molecules.

    摘要翻译: 用于进行表面增强拉曼光谱(SERS)的可调谐装置包括可变形层和设置在可变形层上的一个或多个位置处的多个SERS活性纳米颗粒,其中所述一个或多个位置被配置为用 泵浦波长以使拉曼激发光与纳米颗粒相互作用,并从靠近纳米颗粒的分子产生增强的拉曼散射光。 此外,可变形层的形态被配置为可控地改变以改变由分子产生的拉曼散射光的强度。

    Integrated modular system and method for enhanced Raman spectroscopy
    38.
    发明授权
    Integrated modular system and method for enhanced Raman spectroscopy 有权
    用于增强拉曼光谱的集成模块化系统和方法

    公开(公告)号:US07385691B2

    公开(公告)日:2008-06-10

    申请号:US11044676

    申请日:2005-01-27

    IPC分类号: G01J3/44 G01N21/65

    摘要: Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device for performing Raman spectroscopy comprises a substrate and a laser source disposed on the substrate. The laser source may be configured for emanating a laser radiation, which may irradiate an analyte disposed on a Raman enhancement structure. The Raman enhancement structure may be disposed on the substrate or apart from the substrate. The molecular analysis device also include a radiation receiver disposed on the substrate and configured for receiving a Raman scattered radiation, which may be generated by the irradiation of the analyte and Raman enhancement structure.

    摘要翻译: 公开了用于增强拉曼光谱和超拉曼的装置,系统和方法。 用于执行拉曼光谱的分子分析装置包括设置在基板上的基板和激光源。 激光源可以被配置为发射激光辐射,其可照射设置在拉曼增强结构上的分析物。 拉曼增强结构可以设置在基板上或者离开基板。 分子分析装置还包括设置在基板上并被配置为用于接收可以通过分析物的照射和拉曼增强结构产生的拉曼散射辐射的辐射接收器。

    CHEMICAL-ANALYSIS DEVICE INTEGRATED WITH METALLIC-NANOFINGER DEVICE FOR CHEMICAL SENSING

    公开(公告)号:US20130217143A1

    公开(公告)日:2013-08-22

    申请号:US13879255

    申请日:2010-10-20

    IPC分类号: G01N21/64

    摘要: A chemical-analysis device integrated with a metallic-nanofinger device for chemical sensing. The chemical-analysis device includes a metallic-nanofinger device, and a platform. The metallic-nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A method for using, and a chemical-analysis apparatus including the chemical-analysis device are also provided.