公开(公告)号：US08155263B2

公开(公告)日：2012-04-10

申请号：US12534087

申请日：2009-07-31

申请人： Xiaoye Wu ,  David Allen Langan ,  James Walter LeBlanc ,  Dan Xu

发明人： Xiaoye Wu ,  David Allen Langan ,  James Walter LeBlanc ,  Dan Xu

IPC分类号： H05G1/60

CPC分类号： A61B6/544 ,  A61B6/027 ,  A61B6/032 ,  A61B6/488

摘要： The present invention discloses a computed tomography imager comprising: an x-ray source disposed in a gantry; a detector assembly for receiving an x-ray emission from an x-ray source, the x-ray source and the detector assembly rotatable about an imaging target; an imager control system for selectively modulating a kVp operating value in the x-ray source during a scan slice in accordance with an x-ray modulation software program; and a computer for receiving data from the detector assembly, and for providing control signals to the imager control system by executing the x-ray modulation software program for at least a portion of the total possible rotational scanning range of the x-ray source.

摘要翻译： 本发明公开了一种计算机断层成像仪，包括：设置在台架中的x射线源; 用于从X射线源接收x射线发射的检测器组件，所述x射线源和所述检测器组件围绕成像靶旋转; 成像器控制系统，用于根据x射线调制软件程序在扫描切片期间选择性地调制x射线源中的kVp操作值; 以及计算机，用于从检测器组件接收数据，并且通过对X射线源的总可能的旋转扫描范围的至少一部分执行x射线调制软件程序来向成像器控制系统提供控制信号。

公开(公告)号：US20110142194A1

公开(公告)日：2011-06-16

申请号：US12760862

申请日：2010-04-15

申请人： Naveen Chandra ,  Xiaoye Wu ,  Thomas L. Toth ,  Jiang Hsieh

发明人： Naveen Chandra ,  Xiaoye Wu ,  Thomas L. Toth ,  Jiang Hsieh

IPC分类号： A61B6/03

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/4007 ,  A61B6/405 ,  A61B6/4241 ,  A61B6/482

摘要： A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller configured to apply a first kVp for a first time period, apply a second kVp for a second time period, wherein the second time period is different from the first time period, acquire a first asymmetric view dataset during at least a portion of the first time period, acquire a second asymmetric view dataset during at least a portion of the second time period, and generate an image using the acquired first and second asymmetric view datasets.

摘要翻译： CT系统包括具有用于接收待扫描物体的开口的可旋转机架，以及被配置为在第一时间段施加第一kVp的控制器，在第二时间段施加第二kVp，其中第二时间段是不同的 从所述第一时间段在所述第一时间段的至少一部分期间获取第一非对称视图数据集，在所述第二时间段的至少一部分期间获取第二非对称视图数据集，并且使用所获取的第一和第二时间段生成图像 非对称视图数据集。

公开(公告)号：US07801264B2

公开(公告)日：2010-09-21

申请号：US11959709

申请日：2007-12-19

申请人： Xiaoye Wu ,  James Walter Leblanc ,  Paavana Sainath

发明人： Xiaoye Wu ,  James Walter Leblanc ,  Paavana Sainath

IPC分类号： A61B6/00

CPC分类号： A61B6/583 ,  A61B6/032 ,  A61B6/482 ,  A61B6/505

摘要： A method for calibrating and reconstructing material density images in a dual-spectral computed tomography (CT) system 100 is disclosed. An X-ray source in the CT system 100 emits a first X-ray spectrum and a second X-ray spectrum towards an object. The method includes computing calibration coefficients by using projection data from the object for the two X-ray spectra and by linearizing at least two basis materials such as bone and water simultaneously. Further, basis materials decomposition coefficients for the at least two basis materials are computed by linearizing the basis materials individually. Correction values for the projection data and for the basis materials are then computed by using the basis materials decomposition coefficients and the calibration coefficients. The computed correction values are used in reconstructing material density images for the basis materials.

摘要翻译： 公开了一种用于在双光谱计算机断层摄影（CT）系统100中校准和重建材料密度图像的方法。 CT系统100中的X射线源朝向物体发射第一X射线光谱和第二X射线光谱。 该方法包括通过使用来自对象的两个X射线光谱的投影数据和同时线性化至少两种基础材料例如骨骼和水来计算校准系数。 此外，通过将基础材料单独线性化来计算至少两种基础材料的基础材料分解系数。 然后通过使用基础材料分解系数和校准系数来计算投影数据和基础材料的校正值。 计算的校正值用于重建基础材料的材料密度图像。

公开(公告)号：US07724865B2

公开(公告)日：2010-05-25

申请号：US11843031

申请日：2007-08-22

申请人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

发明人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

IPC分类号： A61B6/00

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4411 ,  A61B6/469 ,  A61B6/482 ,  A61B6/505 ,  A61B6/5205 ,  A61B6/5235 ,  G01T1/249 ,  G06T5/002 ,  G06T5/50 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/20216 ,  G06T2207/30004 ,  G06T2207/30112 ,  H01L27/14676

摘要： A system and method of a diagnostic imaging system includes a high frequency electromagnetic energy source that emits a beam of high frequency electromagnetic energy toward an object to be imaged, a detector that receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source and attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to obtain CT scan data with two or more incident energy spectra, decompose the obtained CT scan data into projection CT data of two or more basis materials, reconstruct linearly weighted projections of the two or more basis materials, determine an optimized energy for the two or more basis materials within a region-of-interest (ROI), and form a monochromatic image of the projection CT data at the optimized energy using the two or more basis material projections.

摘要翻译： 诊断成像系统的系统和方法包括：高频电磁能源，其向待成像对象发射高频电磁能束;检测器，其接收高频电磁能源发射的高频电磁能量，并衰减 通过该目的，可操作地连接到检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。 计算机被编程以获得具有两个或更多个入射能谱的CT扫描数据，将获得的CT扫描数据分解成两个或更多个基础材料的投影CT数据，重建两个或多个基础材料的线性加权投影，确定优化的能量 对于感兴趣区域（ROI）中的两个或更多个基础材料，并且使用两个或更多个基础材料投影在优化的能量下形成投影CT数据的单色图像。

公开(公告)号：US07433443B1

公开(公告)日：2008-10-07

申请号：US11846664

申请日：2007-08-29

申请人： John Eric Tkaczyk ,  Samit Kumar Basu ,  Xiaoye Wu ,  Yanfeng Du

发明人： John Eric Tkaczyk ,  Samit Kumar Basu ,  Xiaoye Wu ,  Yanfeng Du

IPC分类号： H05G1/26

CPC分类号： A61B6/4014 ,  A61B6/032 ,  A61B6/4241 ,  G01T1/2985

摘要： A CT imaging system includes a rotatable gantry having an opening to receive an object to be scanned, a first x-ray emission source attached to the rotatable gantry and configured to emit x-rays toward the object, and a second x-ray emission source attached to the rotatable gantry and configured to emit x-rays toward the object. A first detector is configured to receive x-rays that emit from the first x-ray emission source, and a second detector configured to receive x-rays that emit from the second x-ray emission source. A first portion of the first detector is configured to operate in an integration mode and a first portion of the second detector is configured to operate in at least a photon-counting mode.

摘要翻译： CT成像系统包括可旋转机架，其具有用于接收待扫描物体的开口，附接到可旋转机架并被配置为朝向物体发射x射线的第一x射线发射源，以及第二x射线发射源 附接到可旋转机架并且被配置为朝向物体发射X射线。 第一检测器被配置为接收从第一x射线发射源发射的X射线，以及第二检测器，被配置为接收从第二x射线发射源发射的X射线。 第一检测器的第一部分被配置为以积分模式操作，并且第二检测器的第一部分被配置为以至少光子计数模式操作。

公开(公告)号：US20080137803A1

公开(公告)日：2008-06-12

申请号：US11608162

申请日：2006-12-07

申请人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

发明人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

IPC分类号： A61B6/00 ,  G12B13/00

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/481 ,  A61B6/482 ,  A61B6/583

摘要： A diagnostic imaging system in an example comprises a high frequency electromagnetic energy source, a detector, a data acquisition system (DAS), and a computer. The high frequency electromagnetic energy source emits a beam of high frequency electromagnetic energy toward an object to be imaged and be resolved by the system. The detector receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source. The DAS is operably connected to the detector. The computer is operably connected to the DAS and programmed to employ an inversion table or function to convert N+2 measured projections at different incident spectra into material specific integrals for N+2 materials that comprise two non K-edge basis materials and N K-edge contrast agents. N comprises an integer greater than or equal to 1.

摘要翻译： 示例中的诊断成像系统包括高频电磁能源，检测器，数据采集系统（DAS）和计算机。 高频电磁能源向待成像对象发射高频电磁能束，并由系统解决。 检测器接收高频电磁能源发出的高频电磁能。 DAS可操作地连接到检测器。 计算机可操作地连接到DAS并被编程为采用反演台或功能来将不同入射光谱下的N + 2个测量的投影转换为包含两个非K边缘基础材料的N + 2材料的材料特定积分，并且N K- 边缘造影剂。 N包括大于或等于1的整数。

公开(公告)号：US20080101535A1

公开(公告)日：2008-05-01

申请号：US11553411

申请日：2006-10-26

申请人： Xiaoye Wu ,  James W. LeBlanc ,  Samit Kumar Basu

发明人： Xiaoye Wu ,  James W. LeBlanc ,  Samit Kumar Basu

IPC分类号： H05G1/60 ,  A61B6/00 ,  G01N23/00 ,  G21K1/12

CPC分类号： A61B6/405 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/5235 ,  G01T1/2985

摘要： A CT system in an example comprises one or more high frequency electromagnetic energy sources, a detection assembly, a data acquisition system (DAS), and a computer. The one or more high frequency electromagnetic energy sources emit one or more beams of high frequency electromagnetic energy toward an object to be imaged. The detection assembly is capable of measuring a plurality of projection data at a same projection path that corresponds to a plurality of distinct incident energy spectra. The detection assembly comprises one or more energy discriminating (ED) detectors and/or one or more energy integration (EI) detectors that receive high frequency electromagnetic energy emitted by the one or more high frequency electromagnetic energy sources. The data acquisition system (DAS) is operably connected to the one or more ED detectors and/or the one or more EI detectors. The computer is operably connected to the DAS.

摘要翻译： 示例中的CT系统包括一个或多个高频电磁能源，检测组件，数据采集系统（DAS）和计算机。 一个或多个高频电磁能源朝向要成像的物体发射一个或多个高频电磁能量束。 检测组件能够在对应于多个不同入射能谱的相同投影路径上测量多个投影数据。 检测组件包括一个或多个能量识别（ED）检测器和/或接收由一个或多个高频电磁能源发射的高频电磁能的一个或多个能量积分（EI）检测器。 数据采集​​系统（DAS）可操作地连接到一个或多个ED检测器和/或一个或多个EI检测器。 计算机可操作地连接到DAS。

公开(公告)号：US20060109950A1

公开(公告)日：2006-05-25

申请号：US10904736

申请日：2004-11-24

申请人： Jerome Arenson ,  John Tkaczyk ,  David Ruimi ,  Oded Meirav ,  Evgeny Drapkin ,  Dmitry Samsonov ,  Lev Greenberg ,  Bruno De Man ,  Samit Basu ,  Xiaoye Wu ,  Yangeng Du

发明人： Jerome Arenson ,  John Tkaczyk ,  David Ruimi ,  Oded Meirav ,  Evgeny Drapkin ,  Dmitry Samsonov ,  Lev Greenberg ,  Bruno De Man ,  Samit Basu ,  Xiaoye Wu ,  Yangeng Du

IPC分类号： H05G1/60 ,  A61B6/00 ,  G01N23/00 ,  G21K1/12

CPC分类号： G01T1/1644 ,  A61B6/027 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/583 ,  G01T1/1647 ,  G06T5/002 ,  G06T5/20 ,  G06T2207/10081 ,  G06T2207/30004 ,  G06T2207/30112 ,  Y10S378/901

摘要： An adaptive CT data acquisition system and technique is presented whereby radiation emitted for CT data acquisition is dynamically controlled to limit exposure to those detectors of a CT detector assembly that may be particularly susceptible to saturation during a given data acquisition. The data acquisition technique recognizes that for a given subject size and position that pre-subject filtering and collimating of a radiation beam may be insufficient to completely prevent detector saturation. Therefore, the present invention includes implementation of a number of CT data correction techniques for correcting otherwise unusable data of a saturated CT detector. These data correction techniques include a nearest neighbor correction, off-centered phantom correction, off-centered synthetic data correction, scout data correction, planar radiogram correction, and a number of others. The invention is applicable with energy discriminating CT systems as well as with conventional CT systems and other multi-energy CT systems, such as dual kVp-based systems.

摘要翻译： 提出了一种自适应CT数据采集系统和技术，其中动态地控制用于CT数据采集的辐射，以限制在给定数据采集期间可能特别容易饱和的CT检测器组件的那些检测器的暴露。 数据采集​​技术认识到，对于给定的主体大小和位置，预辐射滤波和辐射束的准直可能不足以完全防止检测器饱和。 因此，本发明包括实现用于校正饱和CT检测器的其他不可用数据的多个CT数据校正技术。 这些数据校正技术包括最近邻校正，偏心幻像校正，偏心合成数据校正，侦察数据校正，平面放射线图校正以及其他数目。 本发明适用于能量识别CT系统以及常规CT系统和其他多能CT系统，例如基于双kVp的系统。

公开(公告)号：US07031426B2

公开(公告)日：2006-04-18

申请号：US10625437

申请日：2003-07-23

申请人： Maria Iatrou ,  Ricardo Scott Avila ,  Peter Michael Edic ,  Jiang Hsieh ,  James Walter LeBlanc ,  Xiaoye Wu

发明人： Maria Iatrou ,  Ricardo Scott Avila ,  Peter Michael Edic ,  Jiang Hsieh ,  James Walter LeBlanc ,  Xiaoye Wu

IPC分类号： A61B6/03

CPC分类号： A61B5/02007 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/405 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482 ,  A61B6/583 ,  A61B17/22 ,  A61B2090/374 ,  A61B2090/376

摘要： A method including detecting components of plaque using a multi-energy computed tomography (MECT) system is provided.

摘要翻译： 提供了一种使用多能计算机断层摄影（MECT）系统检测斑块成分的方法。

公开(公告)号：US06848827B2

公开(公告)日：2005-02-01

申请号：US10437222

申请日：2003-05-13

申请人： Xiaoye Wu ,  James LeBlanc ,  Deborah J. Walter

发明人： Xiaoye Wu ,  James LeBlanc ,  Deborah J. Walter

IPC分类号： A61B6/00 ,  G01D18/00

CPC分类号： A61B6/583

摘要： The present technique provides for the spectral calibration of the detector elements of a CT detector using one or more offset calibration phantoms. The offset phantoms provide greater coverage of the detector elements as well as spectral response data associated with penetration lengths ranging in length from a minimum chord of the phantom to the diameter of the phantom. The spectral response as a function of penetration length can be obtained for each detector element by comparing the fitting of each projection view to the corresponding measured projection view over all view angles. The fitting information may then be employed to derive the coefficients of the spectral response curve for each detector element, which may in turn be employed to provide rapid correction of the spectral response for each element.

摘要翻译： 本技术提供使用一个或多个偏移校准体模的CT检测器的检测器元件的光谱校准。 偏移模型提供了更大的检测器元件的覆盖范围以及与从体模的最小和弦到体模直径的长度范围相关联的光谱响应数据。 通过比较每个投影视图与所有视角上对应的测量投影视图的拟合，可以为每个检测器元件获得作为穿透长度的函数的光谱响应。 然后可以采用拟合信息来导出每个检测器元件的光谱响应曲线的系数，其可以用于提供对于每个元件的光谱响应的快速校正。