公开(公告)号：US08852667B2

公开(公告)日：2014-10-07

申请号：US13318925

申请日：2009-07-10

申请人： Fang Wu ,  Yanfeng Xiao ,  Lei Song ,  Xiaoguang Liu ,  Yi Huang ,  Tao Huang ,  Jiamin Feng

发明人： Fang Wu ,  Yanfeng Xiao ,  Lei Song ,  Xiaoguang Liu ,  Yi Huang ,  Tao Huang ,  Jiamin Feng

IPC分类号： A61L33/00 ,  C23C18/12 ,  C23C4/12 ,  C03C1/00 ,  C03C4/00 ,  C03C3/112 ,  A61L27/32 ,  C03C3/062 ,  C03C3/097

CPC分类号： C23C4/121 ,  A61L27/32 ,  A61L2420/02 ,  C03C1/008 ,  C03C3/062 ,  C03C3/097 ,  C03C3/112 ,  C03C4/0007 ,  C23C4/123 ,  C23C18/1212 ,  C23C18/1245 ,  C23C18/1254 ,  C23C18/1258

摘要： The present invention belongs to the field of biomedical material, and is particularly related to a method of preparing bioactive glass coatings by liquid precursor thermal spray. The objective of the present invention is to overcome the shortcomings of the air plasma spraying where the powder feedstock preparation is complicated and time-consuming, and sol-gel or other wet chemistry method where the synthesized coating generally has thin coating thickness and with low production efficiency. Therefore, a new method is provided for preparation of bioactive glass coatings. In this method, organic and inorganic raw materials were first weighed in accordance with the chemical composition of bioactive glasses, and sol or suspension was prepared; then the sol or suspension was used as the feedstock for thermal spray, and was deposited on the biomedical materials substrate, at high temperature to form the bioactive glass coating. The invention possesses the following advantages: simple operation, less complicated procedures, synthesis with high efficiency, low production cost, suitable for industrial production, and so on. This method can be used to prepare bioactive glass coatings.

摘要翻译： 本发明属于生物医学材料领域，特别涉及通过液体前体热喷涂制备生物活性玻璃涂层的方法。 本发明的目的是克服粉末原料制备复杂和耗时的空气等离子体喷涂的缺点，以及合成涂层通常具有薄的涂层厚度和低生产量的溶胶 - 凝胶或其它湿法化学方法 效率。 因此，提供了用于制备生物活性玻璃涂层的新方法。 在该方法中，首先根据生物活性玻璃的化学成分称量有机和无机原料，制备溶胶或悬浮液; 然后将溶胶或悬浮液用作热喷涂的原料，并在高温下沉积在生物医学材料基材上以形成生物活性玻璃涂层。 本发明具有操作简单，程序复杂程度低，合成效率高，生产成本低，适合工业生产等优点。 该方法可用于制备生物活性玻璃涂层。

公开(公告)号：US08732958B2

公开(公告)日：2014-05-27

申请号：US13609317

申请日：2012-09-11

申请人： Yi Huang

发明人： Yi Huang

IPC分类号： B26B1/04

CPC分类号： B26B1/048

摘要： A locking mechanism for a folding knife includes a thumb post which longitudinally moves along slots in the handle of the knife. The thumb post is urged by a spring loaded locking lever into a notch in the base of the blade of the knife. When so positioned the thumb post retains the blade in an extended position. When the user pushes the thumb post out of the notch, the blade can be folded into the handle of the knife. In another embodiment the thumb post is an integral part of the locking lever, and it is a tab on the locking lever rather than the thumb post engages the notch in the base of the blade.

摘要翻译： 用于折叠刀的锁定机构包括沿着刀的手柄中的狭槽纵向移动的拇指柱。 拇指柱由弹簧加载的锁定杆推动到刀的刀片的基部中的凹口中。 当这样定位时，拇指柱将刀片保持在延伸位置。 当用户将拇指柱推出凹口时，刀片可以折叠到刀柄上。 在另一个实施例中，拇指柱是锁定杆的整体部分，并且其是锁定杆上的突出部，而不是拇指柱接合在刀片的基部中的凹口。

公开(公告)号：US08631153B2

公开(公告)日：2014-01-14

申请号：US12985442

申请日：2011-01-06

申请人： Vasudeva Murthy ,  Sandeep Srivastava ,  Srinivasa R. Guttikonda ,  Tushar Pujara ,  Senguttuvan Haridoss ,  Qin Shi ,  Lloyd Williams ,  Yi Huang ,  Jayanthi Muthukrishnan

发明人： Vasudeva Murthy ,  Sandeep Srivastava ,  Srinivasa R. Guttikonda ,  Tushar Pujara ,  Senguttuvan Haridoss ,  Qin Shi ,  Lloyd Williams ,  Yi Huang ,  Jayanthi Muthukrishnan

IPC分类号： G06F15/173 ,  G06F3/00 ,  G06F13/00

CPC分类号： G06Q10/107

摘要： A system and method for processing and managing electronic requests may include an input module configured to receive a plurality of electronic requests associated with at least one of a product, service, order, and status. The system may comprise a classification module configured to assign each electronic request to at least one category; a transformation module configured to convert the electronic requests into a format compatible with one or more downstream systems; a distribution module configured to distribute the electronic requests based on routing rules to one or more downstream systems, which responds to the at least one request; a management module configured to manage the electronic requests; or a monitoring module configured to present, via a graphical user interface, information associated with at least one of the electronic requests to a user.

摘要翻译： 用于处理和管理电子请求的系统和方法可以包括被配置为接收与产品，服务，订单和状态中的至少一个相关联的多个电子请求的输入模块。 该系统可以包括分类模块，其被配置为将每个电子请求分配给至少一个类别; 变换模块，被配置为将所述电子请求转换为与一个或多个下游系统兼容的格式; 分发模块，被配置为基于路由规则将所述电子请求分发到响应所述至少一个请求的一个或多个下游系统; 配置为管理电子请求的管理模块; 或监视模块，被配置为经由图形用户界面将与至少一个所述电子请求相关联的信息呈现给用户。

公开(公告)号：US20130149372A1

公开(公告)日：2013-06-13

申请号：US13639488

申请日：2010-09-29

申请人： Jianhua Chen ,  Yi Huang ,  Junyu Xiong ,  Caihong Chen

发明人： Jianhua Chen ,  Yi Huang ,  Junyu Xiong ,  Caihong Chen

IPC分类号： C07K7/08 ,  C07K5/00

CPC分类号： C07K7/08 ,  A61K38/07 ,  A61K38/10 ,  C07K5/00 ,  C07K5/101

摘要： Disclosed herein are polypeptides or their derivatives and their application. The polypeptides and their derivatives can treat or prevent cancer. The polypeptides of the invention have significant lethality to the cancer cells when used alone. When its clinical commonly used chemotherapy drugs such as cisplatin in combination, it can significantly increase the sensitivity of chemotherapeutic agents on cancer cells, to enhance its lethality of cancer cells, to reduce the dosage. The peptides can kill a variety of cancer cells, but without apparent toxicity enhancing effect on normal cells. The prepared peptides of the present invention can be chemically synthesized, high-purity, low molecular weight, specificity, non-immunogenic, safe and reliable.

摘要翻译： 本文公开的是多肽或其衍生物及其应用。 多肽及其衍生物可以治疗或预防癌症。 当单独使用时，本发明的多肽对癌细胞具有显着的致死性。 当其临床常用化疗药物如顺铂联合使用时，可显着增加化疗药对癌细胞的敏感性，增强其对癌细胞的致死性，降低剂量。 肽可以杀死各种癌细胞，但对正常细胞没有明显的毒性增强作用。 本发明制备的肽可以化学合成，高纯度，低分子量，特异性，非免疫原性，安全可靠。

公开(公告)号：US20130049078A1

公开(公告)日：2013-02-28

申请号：US13316165

申请日：2011-12-09

申请人： XINPENG WANG ,  Yi Huang ,  Shih-Mou Chang

发明人： XINPENG WANG ,  Yi Huang ,  Shih-Mou Chang

IPC分类号： H01L29/78 ,  H01L21/336

CPC分类号： H01L23/564 ,  H01L21/76801 ,  H01L21/76816 ,  H01L29/66575 ,  H01L29/78 ,  H01L2924/0002 ,  H01L2924/00

摘要： A semiconductor device and a manufacturing method thereof is provided. The method comprises: providing a substrate for the semiconductor device with a gate structure and a first dielectric interlayer being formed thereon, said gate structure comprising a metal gate and an upper surface of said first dielectric interlayer being substantially flush with an upper surface of said gate; forming an interface layer to cover at least the upper surface of said gate such that the upper surface of said gate is protected from being oxidized; and forming a second dielectric interlayer on said interface layer.

公开(公告)号：US20130043516A1

公开(公告)日：2013-02-21

申请号：US13326161

申请日：2011-12-14

申请人： Qiuhua Han ,  Xinpeng Wang ,  Yi Huang

发明人： Qiuhua Han ,  Xinpeng Wang ,  Yi Huang

IPC分类号： H01L29/78 ,  H01L21/306

CPC分类号： H01L21/76802 ,  H01L21/76832 ,  H01L21/76834

摘要： A method for manufacturing a semiconductor device includes forming a contact etch stop layer on an active area of a substrate that has a gate stack formed thereon. The gate stack includes a metal gate and a metal oxide. The contact etch stop layer includes a silicon oxide layer sandwiched between a first and a silicon nitride layers, the second silicon nitride layer is disposed on the active area. The method further includes forming a contact hole extending through an interlayer dielectric layer on the first silicon nitride layer using the first silicon nitride layer as a protection for the active area, removing a portion the first silicon nitride layer disposed at the bottom of the contact hole using the silicon oxide layer as a protection for the active area, and removing the metal oxide using the second silicon nitride layer as a protection for the active area.

摘要翻译： 一种制造半导体器件的方法包括在其上形成有栅极叠层的衬底的有源区上形成接触蚀刻停止层。 栅极堆叠包括金属栅极和金属氧化物。 接触蚀刻停止层包括夹在第一和氮化硅层之间的氧化硅层，第二氮化硅层设置在有源区上。 该方法还包括通过使用第一氮化硅层作为有源区的保护来形成延伸穿过第一氮化硅层上的层间电介质层的接触孔，去除设置在接触孔底部的第一氮化硅层的一部分 使用氧化硅层作为有源区的保护，并且使用第二氮化硅层去除金属氧化物作为有源区的保护。

公开(公告)号：US20130000129A1

公开(公告)日：2013-01-03

申请号：US13609317

申请日：2012-09-11

申请人： Yi Huang

发明人： Yi Huang

IPC分类号： B26B1/04

CPC分类号： B26B1/048

摘要： A locking mechanism for a folding knife includes a thumb post which longitudinally moves along slots in the handle of the knife. The thumb post is urged by a spring loaded locking lever into a notch in the base of the blade of the knife. When so positioned the thumb post retains the blade in an extended position. When the user pushes the thumb post out of the notch, the blade can be folded into the handle of the knife. In another embodiment the thumb post is an integral part of the locking lever, and it is a tab on the locking lever rather than the thumb post engages the notch in the base of the blade.

摘要翻译： 用于折叠刀的锁定机构包括沿着刀的手柄中的狭槽纵向移动的拇指柱。 拇指柱由弹簧加载的锁定杆推动到刀的刀片的基部中的凹口中。 当这样定位时，拇指柱将刀片保持在延伸位置。 当用户将拇指柱推出凹口时，刀片可以折叠到刀柄上。 在另一个实施例中，拇指柱是锁定杆的整体部分，并且其是锁定杆上的突出部，而不是拇指柱接合在刀片的基部中的凹口。

公开(公告)号：US20110286147A1

公开(公告)日：2011-11-24

申请号：US13125752

申请日：2009-10-26

申请人： Yongsheng Chen ,  Yi Huang ,  Yan Wang ,  Yanfeng Ma

发明人： Yongsheng Chen ,  Yi Huang ,  Yan Wang ,  Yanfeng Ma

IPC分类号： H01B1/04 ,  H01G9/00 ,  H01B1/24 ,  H01G2/00

CPC分类号： H01G11/38 ,  H01G11/36 ,  Y02E60/13

摘要： An electrode material comprising 0.5-50 wt % functionalized graphene material and a capacitor comprising the electrode material are provided. A method for preparing the functionalized graphene material is also provided. The method comprises the step of chemically reducing the soluble graphene material and the step of physically reducing the chemically reduced graphene material.

摘要翻译： 提供包含0.5-50重量％的官能化石墨烯材料的电极材料和包含电极材料的电容器。 还提供了制备官能化石墨烯材料的方法。 该方法包括化学还原可溶性石墨烯材料的步骤和物理还原化学还原的石墨烯材料的步骤。

公开(公告)号：US08877283B2

公开(公告)日：2014-11-04

申请号：US13318918

申请日：2009-07-09

申请人： Fang Wu ,  Yi Huang ,  Lei Song ,  Xiaoguang Liu ,  Yanfeng Xiao ,  Jiamin Feng ,  Jiyong Chen

发明人： Fang Wu ,  Yi Huang ,  Lei Song ,  Xiaoguang Liu ,  Yanfeng Xiao ,  Jiamin Feng ,  Jiyong Chen

IPC分类号： A61L33/00 ,  A61L27/32 ,  C23C4/12 ,  C23C4/10 ,  A61L27/56

CPC分类号： A61L27/32 ,  A61L27/56 ,  C23C4/11 ,  C23C4/134

摘要： The present invention relates to a preparation method for porous hydroxyapatite coatings. In particular, it is a method of using suspension plasma spraying to prepare porous hydroxyapatite coatings, which belongs to the technical field of biomedical material preparations. The present invention added a pore-forming agent into the hydroxyapatite suspension with a solid content of 16%-45%. After full stirring, the feedstock materials for plasma spraying were transferred into the injection system, and injected into the high temperature area of the central plasma flame. Then, the feedstock materials made the heat exchange with the high plasma flame of plasma spraying gun. Then the sprayed raw materials were subjected to breakup and refinement of the droplets, solvent evaporation, the decomposition and gasification of the pore-forming agent and melting of feedstock materials. Finally, the porous hydroxyapatite coatings are directly deposited onto the substrate surfaces of the biomedical materials.

摘要翻译： 本发明涉及一种多孔羟基磷灰石涂料的制备方法。 特别是采用悬浮等离子喷涂法制备多孔羟基磷灰石涂层的方法，属于生物医药材料制备技术领域。 本发明在固体含量为16％-45％的羟基磷灰石悬浮液中加入成孔剂。 充分搅拌后，将用于等离子体喷涂的原料转移到注射系统中，并注入中心等离子体火焰的高温区域。 然后，原料与等离子体喷枪的高等离子体火焰进行热交换。 然后将喷雾的原料进行液滴的分解和精制，溶剂蒸发，造孔剂的分解和气化以及原料的熔化。 最后，将多孔羟基磷灰石涂层直接沉积在生物医学材料的基材表面上。

公开(公告)号：US20140062981A1

公开(公告)日：2014-03-06

申请号：US13601849

申请日：2012-08-31

申请人： Yi Huang ,  Mingxia Gu ,  Jean-Jacques Philippe Drolet ,  Wei Chen

发明人： Yi Huang ,  Mingxia Gu ,  Jean-Jacques Philippe Drolet ,  Wei Chen

IPC分类号： G09G5/00 ,  G02F1/1335 ,  H01L31/18 ,  G02F1/1343

CPC分类号： G09G3/3648 ,  G02F1/133382 ,  G09G2300/0426 ,  G09G2300/043 ,  G09G2320/0242 ,  G09G2320/041

摘要： Systems, methods, and devices are provided for an electronic display with thermally compensated pixels. Such an electronic display may have an array of pixels, at least some of which may be thermally compensated pixels that exhibit reduced thermal color shift over an operational temperature range. These thermally compensated pixels may have compensation electrodes that induce an electric field in the thermally compensated pixel that cause a reduction in color shift.

摘要翻译： 为具有热补偿像素的电子显示器提供系统，方法和装置。 这样的电子显示器可以具有像素阵列，其中至少一些可以是在工作温度范围内表现出减少的热色移的热补偿像素。 这些热补偿像素可以具有在热补偿像素中感应导致颜色偏移减小的电场的补偿电极。