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公开(公告)号：USD925330S1
公开(公告)日：2021-07-20
申请号：US29707949
申请日：2019-10-02
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公开(公告)号：US20210087709A1
公开(公告)日：2021-03-25
申请号：US16971752
申请日：2019-02-22
发明人： Ka Y. KWONG , Ilia V. DAVYDOV
摘要： The invention provides singleplex and multiplex assays for screening of antigen-binding molecules for their affinity to antigens by normalizing for the concentration of the antigen-binding molecule.
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公开(公告)号：US10935547B2
公开(公告)日：2021-03-02
申请号：US15222674
申请日：2016-07-28
发明人： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeffery D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
IPC分类号： G01N33/543 , B01L3/00 , B01L9/00 , C12Q1/00 , G01N27/30 , G01N21/76 , B01J19/00 , B33Y80/00 , C40B40/10
摘要： Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
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公开(公告)号：US20210048431A1
公开(公告)日：2021-02-18
申请号：US16978464
申请日：2019-03-08
申请人： MESO SCALE TECHNOLOGIES, LLC. , GEORGETOWN UNIVERSITY , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人： Jeff DEBAD , Joshua GATSON , Mark BURNS , Arianna BIESSO
摘要： The present invention relates to assays, methods, and kits to assess traumatic brain injury (TBI) in a subject. The present invention also relates to ultrasensitive assays for GFAP, tau, CKBB, IL-1β, IL-2, IL-6, IL-10, IL-22, IP-10, TNFα, TSLP, NFL, and/or NFH.
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公开(公告)号：US20210016288A1
公开(公告)日：2021-01-21
申请号：US16929757
申请日：2020-07-15
发明人： Gary I. KRIVOY , Cecilia ZIMMERMAN , Jules VANDERSARL , Sandor KOVACS , Aaron H. LEIMKUEHLER , Leo TABAKIN , Jon WILLOUGHBY , Manish KOCHAR , Charles M. Clinton
IPC分类号： B01L9/00
摘要： Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：USD907878S1
公开(公告)日：2021-01-12
申请号：US29724913
申请日：2020-02-20
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公开(公告)号：US20200240903A1
公开(公告)日：2020-07-30
申请号：US16845560
申请日：2020-04-10
发明人： Jacob N. Wohlstadter , Eli Glezer , James Wilbur , George Sigal , Kent Johnson , Charles Clinton , Alan Kishbaugh , Bandele Jeffrey-Coker , Jeff D. Debad , Alan B. Fischer
摘要： Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
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公开(公告)号：US10725059B2
公开(公告)日：2020-07-28
申请号：US15564581
申请日：2016-04-06
IPC分类号： G01N35/00 , B01F11/00 , G01N35/10 , G01N33/543 , B06B1/16
摘要： The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.
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公开(公告)号：USD880096S1
公开(公告)日：2020-03-31
申请号：US29591981
申请日：2017-01-25
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公开(公告)号：US20190391140A1
公开(公告)日：2019-12-26
申请号：US16564208
申请日：2019-09-09
发明人： Anahit Aghvanyan , Eli N. Glezer , John Kenten , George Sigal , Martin Stengelin , David Routenberg
IPC分类号： G01N33/543 , C12Q1/6844 , C12Q1/6837 , C12Q1/6832
摘要： The present invention is directed to methods for improving assay specificity and performance in binding assays.
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