公开(公告)号：US20220299502A1

公开(公告)日：2022-09-22

申请号：US17827499

申请日：2022-05-27

申请人： SYSMEX CORPORATION

发明人： Chikayuki TSURUNO ,  Shinya NAGAI ,  Minako TERAO ,  Chika MIZUTA ,  Takuya KYOUTOU

IPC分类号： G01N33/53 ,  G01N33/574

摘要： The present invention relates to a method for detecting a target substance that is useful for detection of a glycoprotein and the like comprising a specific sugar chain, a reagent for detecting a target substance, a carrier and a method for manufacturing the carrier.

公开(公告)号：US20220292855A1

公开(公告)日：2022-09-15

申请号：US17691793

申请日：2022-03-10

申请人： SYSMEX CORPORATION

发明人： Shoichiro Asada ,  Konobu Kimura ,  Masamichi Tanaka ,  Kenichiro Suzuki

IPC分类号： G06V20/69 ,  G01N35/00 ,  G06N3/08 ,  G06T7/00 ,  G01N33/49

摘要： Disclosed is an analysis method for a specimen using an analyzer connected to a host computer, the analysis method including: obtaining, with respect to each of a plurality of cells contained in the specimen, feature data of the cell; generating classification information in which each of the cells is classified into a plurality of cell types, by analyzing the feature data with use of an artificial intelligence algorithm and performing classifying; generating a measurement result of the specimen on the basis of the classification information; displaying, on a display part of the analyzer, the measurement result and at least a part of the classification information; and transmitting, to the host computer, output data that includes the measurement result and in which at least a part of the classification information has been removed.

公开(公告)号：US20220283194A1

公开(公告)日：2022-09-08

申请号：US17685596

申请日：2022-03-03

申请人： SYSMEX CORPORATION

发明人： Yuji WAKAMIYA ,  Toru UEMURA ,  Yuichiro OHMAE ,  Hidetaka HAYAMA

IPC分类号： G01N35/00 ,  G01N35/02

摘要： A quality control method of a specimen analysis system is disclosed, including: receiving a setting of a quality control measurement condition from a user; determining at least one quality control specimen to be used for quality control measurement from among a plurality of the quality control specimens stored in a storage, according to the quality control measurement condition and information on the quality control specimens that are stored in the storage section; taking out the determined quality control specimen from the storage; transporting the determined quality control specimen to a measurement unit; and measuring the transported quality control specimen by the measurement unit.

公开(公告)号：US20220283083A1

公开(公告)日：2022-09-08

申请号：US17686802

申请日：2022-03-04

申请人： SYSMEX CORPORATION ,  OSAKA UNIVERSITY ,  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

发明人： Masaya OKADA ,  Yuki SHIMAOKA ,  Shigeki IWANAGA ,  Kazuki BANDO ,  Katsumasa FUJITA ,  Yasunori NAWA ,  Satoshi FUJITA

IPC分类号： G01N21/31 ,  G01N21/25

摘要： Disclosed is an analytical method for analyzing a test substance contained in a measurement sample, the method comprising: generating a data set based on a plurality of optical spectra acquired from a plurality of locations in the measurement sample; inputting the data set into a deep learning algorithm having a neural network structure; and outputting information on the test substance, on the basis of an analytical result from the deep learning algorithm.

公开(公告)号：US11422143B2

公开(公告)日：2022-08-23

申请号：US16286105

申请日：2019-02-26

申请人： SYSMEX CORPORATION

发明人： Takashi Yamato ,  Jun Inagaki ,  Shunsuke Saito ,  Yoshinori Nakamura

IPC分类号： G01N35/10 ,  G01N35/00

摘要： The sample measuring apparatus includes a suction unit that includes a nozzle and a drive unit that raises and lowers the nozzle, and suctions a first liquid and a second liquid that is different from the first liquid; a liquid surface detecting unit that detects liquid surfaces of the first liquid and the second liquid; a control unit that controls the suction unit, and a measuring unit that measures a measurement sample prepared from the suctioned first liquid; wherein the control unit controls the suction unit to suction the first liquid and the second liquid based on the respective liquid surface detection result of the first liquid and the second liquid detected while lowering the nozzle, and a second speed at which the nozzle descends when detecting the liquid surface of the second liquid is faster than a first speed at which the nozzle descends when detecting the liquid surface of the first liquid.

公开(公告)号：US11406982B2

公开(公告)日：2022-08-09

申请号：US16204473

申请日：2018-11-29

申请人： SYSMEX CORPORATION

发明人： Koji Ikeda ,  Hiroyuki Fujino ,  Mieko Asada

IPC分类号： B01L3/00 ,  G16H40/63 ,  G16H10/40 ,  G16H40/40

摘要： A reagent kit in which a brief measurement result is readily associated with subject information by suppressing erroneous input without using an integrated management system. This reagent kit 100 includes a container 10 used for measuring a sample by the sample measuring apparatus 300, a first identification label 30 including first identification information 31 associated with the measurement result 51 of the sample, and a second identification label 40 including second identification information 41 associated with the first identification information 31.

公开(公告)号：US20220228194A1

公开(公告)日：2022-07-21

申请号：US17575924

申请日：2022-01-14

申请人： SYSMEX CORPORATION

发明人： Masahiro MIURA ,  Kenji AKAMA ,  Masaaki KAWAI ,  Masaya OKADA ,  Kentaro SHIRAI ,  Yuichiro YOSHIDA ,  Tasuku YOTORIYAMA ,  Michitaka NOTOYA ,  Soichi OUE

IPC分类号： C12Q1/686

摘要： In an example of an embodiment, a first sample set is prepared that includes a test sample prepared from a first subject sample and a reagent, and at least one control sample prepared from at least one of a positive control and a negative control, and a second sample set is prepared that includes a test sample prepared from a second subject sample and a reagent and does not contain at least one of the control samples contained in the first sample set. The nucleic acid amplification in the first sample set is measured in the first unit, the nucleic acid amplification in the second sample set is measured in the second unit, and the measurement result of each test sample contained in the first sample set and second sample set is analyzed based on the measurement result of the control sample contained in at least the first sample set.

公开(公告)号：US11366127B2

公开(公告)日：2022-06-21

申请号：US16056584

申请日：2018-08-07

申请人： SYSMEX CORPORATION

发明人： Ken Nishikawa ,  Tetsuya Oda ,  Hidetaka Hayama

IPC分类号： G01N1/00 ,  G01N35/00 ,  G01N1/28 ,  G01N1/30

摘要： A testing system according to one or more embodiments may include: a smear preparing apparatus that prepares a smear slide by smearing a sample on a glass slide; a smear transporting apparatus that transports the smear slide; a controller; and a display part. The controller may cause the display part to display a selection screen on which one or more of the smear preparing apparatus and the smear transporting apparatus can be selected. Based on a selection on the selection screen, the one or more of the smear preparing apparatus and the smear transporting apparatus selected on the selection screen may run respective start operations.

公开(公告)号：US20220177922A1

公开(公告)日：2022-06-09

申请号：US17436208

申请日：2020-03-09

申请人： National University Corporation Tokyo Medical and Dental University ,  SYSMEX CORPORATION

发明人： Hiroshi ASAHARA ,  Ryota KURIMOTO ,  Takahide MATSUSHIMA ,  Hiroki TSUTSUMI

IPC分类号： C12N15/90

摘要： One of the purposes of the present invention is to provide a method for producing a gene-edited tissue stem cell in an undifferentiated state within a short period of time. Another one of the purposes of the present invention is to provide a method for treating and/or preventing a disease using a gene-edited tissue stem cell in an undifferentiated state. A gene-edited tissue stem cell is produced by a method comprising a step for editing the gene sequence of a target gene in tissue stem cells, and a step for selecting the tissue stem cells having an edited gene sequence, and optionally, further comprising a step for adding a tag to the gene sequence of the target gene and/or a step for activating gene expression of the target gene in the tissue stem cells. The tissue stem cell thus produced is used in treating/preventing diseases.

公开(公告)号：US11287380B2

公开(公告)日：2022-03-29

申请号：US16204443

申请日：2018-11-29

申请人： SYSMEX CORPORATION

发明人： Yuki Akasaka

IPC分类号： G01N15/14 ,  G06T7/00 ,  G01N21/64 ,  G01N15/10

摘要： An image analysis apparatus and an image analysis method capable of appropriately analyzing whether an analysis target cell is an abnormal cell even when a subject has a chromosomal abnormality are provided. An image analysis apparatus 10 includes light sources 121 and 122 configured to irradiate light onto a sample 21 whose target portion is labeled, an imaging unit 154 for capturing light generated from the sample 21 by irradiation with light, and a processing unit 11 that processes the image captured by the imaging unit 154. The processing unit 11 acquires information on the chromosomal abnormality and analyzes the image based on the information on the acquired chromosome abnormality.