公开(公告)号：US07842315B2

公开(公告)日：2010-11-30

申请号：US11872696

申请日：2007-10-15

申请人： Chang Gue Son

发明人： Chang Gue Son

IPC分类号： A61K36/00 ,  A61K36/076 ,  A61K36/9064 ,  A61K36/484 ,  A61K36/282 ,  A61K36/537

CPC分类号： A61K36/282

摘要： Disclosed is a composition for hepatoprotection, or for prevention or treatment of liver fibrosis or cirrhosis, which comprises as an active ingredient a water extract of a mixture of Trionycis Carapax, Raphani Semen, Artemisia capillaris Herba, Atractylodis Macrocephalae Rhizoma, Poria cocos, Alismatis Rhizoma, Atractylodis Rhizoma, Salvia Miltiorrhizae Radix, Polyporus, Amomi Fructus, Ponciri Fructus, Glycyrrhizae Radix and Helenii Radix.

摘要翻译： 本发明公开了一种用于肝保护或预防或治疗肝纤维化或肝硬化的组合物，其包含作为活性成分的苦参茯苓，拉法精，艾蒿，白术，茯苓，茜草， ，Atractylodis Rhizoma，Salvia Miltiorrhizae Radix，Polyporus，Amomi Fructus，Ponciri Fructus，Glycyrrhizae Radix和Helenii Radix。

公开(公告)号：US20060013825A1

公开(公告)日：2006-01-19

申请号：US10892393

申请日：2004-07-16

申请人： Bjorn Kristiansen

发明人： Bjorn Kristiansen

IPC分类号： A61K36/07 ,  A61K36/074 ,  A61K36/076

CPC分类号： A61K36/076 ,  A61K36/07 ,  A61K36/074 ,  Y02A50/463 ,  Y02A50/465 ,  Y02A50/471 ,  Y02A50/473 ,  Y02A50/481

摘要： The present invention relates to compositions comprising polypeptides and polysaccharides. The compositions are in general immune modulating. The invention also discloses methods of producing these compositions using filamentous fungi cultivated in liquid medium. The compositions are useful for example in the treatment of immune compromised conditions.

公开(公告)号：US12115204B2

公开(公告)日：2024-10-15

申请号：US17790646

申请日：2021-01-05

申请人： NANTONG UNIVERSITY

发明人： Xiaosong Gu ,  Chunkang Tang ,  Fei Ding ,  Xiaoming Yang ,  Qiong Cheng ,  Hualin Sun ,  Lai Xu

IPC分类号： A61K36/481 ,  A61K35/583 ,  A61K36/076 ,  A61K36/21 ,  A61K36/232 ,  A61K36/284 ,  A61K36/286 ,  A61K36/64 ,  A61K36/725 ,  A61K36/815

CPC分类号： A61K36/481 ,  A61K35/583 ,  A61K36/076 ,  A61K36/21 ,  A61K36/232 ,  A61K36/284 ,  A61K36/286 ,  A61K36/64 ,  A61K36/725 ,  A61K36/815 ,  A61K2236/13 ,  A61K2236/331 ,  A61K2236/51

摘要： Disclosed are a compound preparation for neuranagenesis, and a preparation method therefor and the use thereof. The compound preparation for neuranagenesis comprises the raw medicinal materials in parts by weight: 10-20 parts of raw Astragali radix, 10-20 parts of Rehmaimiae Radix praeparata, 10-20 parts of Actyranthes bidentata, 6-15 parts of Jujubae fructus, 6-15 parts of Lycii fructus, 6-15 parts of parched Ziziphi spinosae semen, 6-12 parts of Angelicae smensis radix, 3-9 parts of Carthami flos, 6-15 parts of Poria, 6-15 parts of parched Atractylodis macrocephalae rhizoma and 10-20 parts of Zaocys. The compound preparation can be used for preparing drugs to treat nerve damage diseases, and can be prepared into oral liquids, granules, dissolved granules and tablets.

公开(公告)号：US20240325478A1

公开(公告)日：2024-10-03

申请号：US18621062

申请日：2024-03-28

申请人： Ningxia Medical University ,  Ningxia Freedom Biological Pharmaceutical Technology Co., LTD

发明人： Rui He ,  Guangyong Li ,  Xiaojiang Chen ,  Xiaoli Du ,  Xiangdong Zhu ,  Huiming Ma ,  Miao Sun ,  Jiafuruzi He

IPC分类号： A61K36/232 ,  A61K36/076 ,  A61K36/185 ,  A61K36/235 ,  A61K36/236 ,  A61K36/24 ,  A61K36/284 ,  A61K36/344 ,  A61K36/48 ,  A61K36/481 ,  A61K36/484 ,  A61K36/54 ,  A61K36/62 ,  A61K36/67 ,  A61K36/714 ,  A61K36/754 ,  A61K36/894 ,  A61K36/9062 ,  A61K36/9068 ,  A61P15/08

CPC分类号： A61K36/232 ,  A61K36/076 ,  A61K36/185 ,  A61K36/235 ,  A61K36/236 ,  A61K36/24 ,  A61K36/284 ,  A61K36/344 ,  A61K36/48 ,  A61K36/481 ,  A61K36/484 ,  A61K36/54 ,  A61K36/62 ,  A61K36/67 ,  A61K36/714 ,  A61K36/754 ,  A61K36/894 ,  A61K36/9062 ,  A61K36/9068 ,  A61P15/08 ,  A61K2236/331

摘要： A traditional Chinese medicine compound for improving testicular dysfunction is made from the following raw materials: Codonopsis pilosula, Astragalus membranaceus, Dioscorea opposita, Angelica sinensis, Atractylodes macrocephala, Poria cocos, Cynanchum otophyllum, Psoralea corylifolia, Ligusticum chuanxiong, Nelumbo nucifera, Euryale ferox, Amomum villosum, Alpinia katsumadai, Foeniculum vulgare, Cinnamomum cassia, Evodia ruticarpa, Piper nigrum, Zingiber officinale, Aconitum carmichaelii, and Glycyrrhiza uralensis. All the raw materials are combined, so that the spleen, the stomach and the kidney are in harmony, the qi, the blood and the body fluid are recovered, and the kidney essence is active. Animal experiments show that the traditional Chinese medicine compound can up-regulate expressions of phosphatidylinositol 3-kinase (PI3K), phospho-protein kinase B (p-AKT) and B-cell lymphoma-2 (Bcl-2), improve testicular dysfunction, improve hormone secretion, regulate a male reproductive endocrine environment of the body, and further improve semen parameters.

公开(公告)号：US20240307458A1

公开(公告)日：2024-09-19

申请号：US18572711

申请日：2022-06-21

申请人： SAO THAI DUONG JOINT STOCK COMPANY

发明人： Thi Huong Lien NGUYEN

IPC分类号： A61K35/586 ,  A61K31/192 ,  A61K35/32 ,  A61K36/076 ,  A61K36/258 ,  A61K36/484 ,  A61K36/54 ,  A61K36/736 ,  A61K36/76 ,  A61K38/48 ,  A61P19/02

CPC分类号： A61K35/586 ,  A61K31/192 ,  A61K35/32 ,  A61K36/076 ,  A61K36/258 ,  A61K36/484 ,  A61K36/54 ,  A61K36/736 ,  A61K36/76 ,  A61K38/482 ,  A61P19/02 ,  A61K2236/13 ,  A61K2236/331 ,  A61K2236/37 ,  A61K2236/39 ,  A61K2236/51

摘要： The present invention relates to a medicine composition for treatment of bone and joint diseases that has its ingredients (% by weight) as the dried extract of medicinal herbs: 40-75; tortoiseshell extract: 0.1-20; mixed bone extract: 0.1-20; deer antler extract: 0.1-20; salix alba extract: 5-25; nattokinase: 0.1-10; and Na-benzoate: 0-0.5, wherein the herbal medicine mixture comprises the ingredients of: Huang Bai (bark), Liquorice (root/rhizome), Hardy rubber tree (bark), Ox Knee (root), Fang Feng (root), Poria cocos wolf (fruit body), Chinese foxglove (rhizome), Sang Ji Sheng (whole tree), Gentian Root (root), Rhizoma Anemarrhena (rhizome), Peach blossom (blossom), Dried tangerine peel (peel), Chinese peony (root), Dangshen (root), Ginseng (root) Du Huo (root), Dongquai (root), Cinnamon (bough), Xi Xin (root, rhizome), Szechuan lovage (rhizome) and Dwarf umbrella tree (root). The present invention also relates to a process for producing medicine composition for treatment of bone and joint diseases mentioned above.

公开(公告)号：US20240269211A1

公开(公告)日：2024-08-15

申请号：US18167842

申请日：2023-02-11

申请人： Centre for Chinese Herbal Medicine Drug Development Limited

发明人： Zhaoxiang BIAN ,  Chengyuan LIN ,  Haitao XIAO ,  Lixiang ZHAI ,  Hor Yue TAN

IPC分类号： A61K36/344 ,  A61K36/076 ,  A61K36/284 ,  A61K36/40 ,  A61K36/484 ,  A61K36/718 ,  A61K36/74 ,  A61K36/898 ,  A61K36/9066 ,  A61P1/12

CPC分类号： A61K36/344 ,  A61K36/076 ,  A61K36/284 ,  A61K36/40 ,  A61K36/484 ,  A61K36/718 ,  A61K36/74 ,  A61K36/898 ,  A61K36/9066 ,  A61P1/12

摘要： The present invention belongs to the technical field of pharmaceuticals, and particularly relates to a green and healthy medicine composition for preventing and treating inflammatory bowel disease. The medicine composition comprises: 15-25 g of roots of Codonopsis pilosula (Franch.) Nannf., 5-15 g of Atractylodes macrocephala Koidz., 15-25 g of Poria cocos (Schw.) Wolf, 1-10 g of Cornus officinalis Sieb. et Zucc., 1-10 g of Coptis chinensis Franch., 1-10 g of Curcuma Longa L., 5-15 g of Paederia scandens (Lour.) Merr., 5-15 g of Bletilla striata (Thunb.) Reichb.f., and 1-10 g of Glycyrrhiza uralensis Fisch. The solution disclosed by the present application has significant beneficial effect on the prevention and treatment of inflammatory bowel disease, and the herbs used in the present application are widely used traditional Chinese medicine products with no or low toxic effect; therefore, the green and healthy medicine composition has green, healthy and safe technical advantages.

公开(公告)号：US20240115640A1

公开(公告)日：2024-04-11

申请号：US18544500

申请日：2023-12-19

申请人： Chenland Nutritionals Inc. ,  Qingdao Chenlan Drug Co., Ltd

发明人： Shengcan Zou ,  Dongli Yin ,  Jinli Chen ,  Jinli Liu ,  Decui Yin ,  Haijun Zhang

IPC分类号： A61K36/258 ,  A61K36/076 ,  A61K36/64 ,  A61P39/06

CPC分类号： A61K36/258 ,  A61K36/076 ,  A61K36/64 ,  A61P39/06 ,  A61K2236/331 ,  A61K2236/333 ,  A61K2236/51

摘要： A method for preparing ginseng extract rich in rare ginsenosides is disclosed. Ginseng roots or ginseng stems and leaves are extracted, enzymatically hydrolyzed and treated with high temperature and high pressure. The preparation method can quickly and effectively increase the proportion of rare ginsenosides in the ginseng extract. After in vitro antioxidant experiments and in vivo experiments with Hidradenitis elegans nematode, the extract and related complexes were proved to be effective in antioxidant, anti-oxidative stress, and improving age-related muscle decline and other dysfunctions. After genetic and metabolomic studies, the anti-aging mechanism was proved to be related to the expression of genes associated with nutrient sensing, stress-related pathways and redox processes, and showed innate immune response and redox process GO enrichment, proving its oxidative stress resistance.

公开(公告)号：US11771727B2

公开(公告)日：2023-10-03

申请号：US17656554

申请日：2022-03-25

申请人： Qingdao Baishishankang Traditional Chinese Medicine Technology Co., Ltd.

发明人： Ping Lin ,  Zixuan Lin

IPC分类号： A61K36/232 ,  A61K36/605 ,  A61K36/77 ,  A61K36/076 ,  A61K36/8945 ,  A61K36/8969 ,  A61K36/482 ,  A61K36/23 ,  A61K36/725 ,  A61K36/9068 ,  A61K36/54 ,  A61K36/752 ,  A61K36/254 ,  A61P25/20 ,  A61K36/185 ,  A61K36/07

CPC分类号： A61K36/232 ,  A61K36/07 ,  A61K36/076 ,  A61K36/185 ,  A61K36/23 ,  A61K36/254 ,  A61K36/482 ,  A61K36/54 ,  A61K36/605 ,  A61K36/725 ,  A61K36/752 ,  A61K36/77 ,  A61K36/8945 ,  A61K36/8969 ,  A61K36/9068 ,  A61P25/20 ,  A61K2236/15

摘要： The disclosure relates to a traditional Chinese medicine composition and product for improving sleep by balancing yin and yang, a method for making the same and use thereof, and belongs to the technical field of traditional Chinese medicine. The disclosure provides a traditional Chinese medicine composition for improving sleep by balancing yin and yang, which has reasonable compatibility of all herbal medicines, nourishes yin to suppress yang, tonifies blood and promotes blood, regulates qi and soothes the nerves, and has the functions of reconciling yin and yang and balancing qi and blood. The composition may fundamentally improve sleep quality, with an effective rate of 100%. At the same time, all the medicines in the prescription are raw materials of medicine food homology, which are safe and effective, not cause side effects and mental dependence on the human body, and may be taken for a long time.

公开(公告)号：US11458181B2

公开(公告)日：2022-10-04

申请号：US16881006

申请日：2020-05-22

申请人： Ying-Jih Chao Lee

发明人： Ying-Jih Chao Lee

IPC分类号： A61K36/64 ,  A61K36/40 ,  A61K36/8945 ,  A61K36/884 ,  A61P3/06 ,  A61K36/076 ,  A61K36/714 ,  A61K36/54 ,  A61K36/65

摘要： An herbal formula used for preparing a pharmaceutical composition for preventing and treating metabolic syndrome is provided. The herbal formula includes Rehmanniae radix preparata, Cornus officinalis, Dioscorea polystachya, Alisma plantago-aquatica, Paeonia suffruticosa, Poria cocos, Aconitum carmichaeli, and Cinnamomum cassia.

公开(公告)号：US11324790B2

公开(公告)日：2022-05-10

申请号：US16995903

申请日：2020-08-18

申请人： Da-Tong Ju

发明人： Hsuan-Ching Tseng ,  Da-Tong Ju ,  Sung-Sen Yang ,  Wei-Te Cheng ,  Chen-Yu Lee ,  Yan-Chih Liao ,  Juei-Yang Lo ,  Luan-Yao Chien

IPC分类号： A61K36/282 ,  A61K36/808 ,  A61K36/40 ,  A61K36/284 ,  A61K36/756 ,  A61K36/484 ,  A61K36/21 ,  A61K36/8945 ,  A61K36/076 ,  A61K36/65 ,  A61K36/81 ,  A61K36/31 ,  A61K36/64

摘要： A method for treating a side effect caused by bacillus Calmette-Guérin (BCG) perfusion therapy for bladder cancer includes: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture comprising Rhizoma anemarrhenae, Cortex phellodendri, Glycyrrhiza uralensis, Rehmanniae Radix, Fructus corni, Rhizoma dioscoreae, Poria, Moutan cortex, Rhizoma Alismatis, Radix achyranthis bidentatae, and Atractylodes lancea.