Oral compositions comprising beta-escin for reducing acetaldehyde toxicity

    公开(公告)号:US10799550B2

    公开(公告)日:2020-10-13

    申请号:US16461967

    申请日:2017-11-24

    发明人: Katarzyna Koziak

    摘要: The present invention relates to an oral liquid composition comprising β-escin (beta-escin) and chokeberry fruit extract for use in treatment and prevention of conditions related to the increased acetaldehyde toxicity, such as veisalgia, alcohol poisoning, esophageal cancer, oropharyngolaryngeal cancer or a condition resulting from insufficient aldehyde dehydrogenase (ALDH) enzyme activity. Administration of the composition of the invention to a subject results in an increased metabolism of aldehydic substrates, in particular those originating from catabolism of alcohol and representing a hazard to humans due to their toxicity.

    Formulations for weight loss and methods of use

    公开(公告)号:US10765718B2

    公开(公告)日:2020-09-08

    申请号:US15887666

    申请日:2018-02-02

    申请人: GOLO LLC

    摘要: A weight loss composition including banaba leaf extract, apple fruit extract, Rhodiola root extract, zinc chelate, and magnesium chelate are described. The weight loss composition may further include gardenia fruit extract, chromium chelate, Salacia extract, berberine, inositol, or mixtures thereof. Embodiments are also directed to a bulk food product and a weight management plan, which may be used in conjunction with the weight loss composition. Embodiments are also directed to kits and methods of use for treating or preventing obesity, promoting weight loss, and improving insulin resistance.