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公开(公告)号:US20220072203A1
公开(公告)日:2022-03-10
申请号:US17126449
申请日:2020-12-18
Applicant: POSTECH Research and Business Development Foundation , THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor: Dong-Woo CHO , Wonil Han , Narendra K. Singh , Yong Kyun Kim , Sun Ah Nam
Abstract: The present disclosure is related to a perfusable-type bio-dual proximal tubule cell construct and a producing method thereof capable of applying an in vitro artificial organ model configured to include a first bioink comprising a decellularized substance derived from a mammalian kidney tissue and human umbilical vascular endothelial cells (HUVECs) and a second bioink comprising the decellularized substance and renal proximal tubular epithelial cells (RPTECs), wherein the first bioink and the second bioink are coaxial and printed in tubular constructs having different inner diameters.
According to the present disclosure, it is possible to use the renal proximal tubule-on-a-chip as a bioreactor capable of observing a biological drug reaction similar to a real drug by perfusing various drugs to the renal proximal tubule-on-a-chip.-
公开(公告)号:US20220056338A1
公开(公告)日:2022-02-24
申请号:US17407260
申请日:2021-08-20
Inventor: Yong Wook KIM , Yong ju KWON , Sungjee KIM , Jihyun MIN , Yuho WON , Eun Joo JANG , Hyo Sook JANG , Eunjae LEE , Kyuhyun BANG , Anastasia AGNES , Jeongmin KIM
Abstract: The invention relates to InP-based nanoclusters that include indium and phosphorus and further include zinc, chlorine, or a combination thereof, and to a method of preparing the InP-based nanoparticles including heating the InP-based nanoclusters in the presence of zinc, chlorine, or a combination thereof.
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公开(公告)号:US11193962B2
公开(公告)日:2021-12-07
申请号:US16848153
申请日:2020-04-14
Inventor: Jae Yoon Sim , Young Woo Ji
IPC: G05F3/02 , G01R19/165 , G01R19/17 , G05F3/10
Abstract: An electronic circuit includes first to third transistors. The first transistor has a first channel width and a first channel length and generates a first potential difference by passing an operating current based on a first operating voltage. The second transistor has a second channel width and a second channel length and generates a second potential difference based on the operating current. The third transistor generates a third potential difference based on a second operating voltage and the operating current. A sum of a level of the first operating voltage and a level of the first potential difference corresponds to a sum of a level of the second operating voltage, a level of the second potential difference, and a level of the third potential difference. The first channel width is greater than the second channel width, or the first channel length is longer than the second channel length.
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公开(公告)号:US20210340475A1
公开(公告)日:2021-11-04
申请号:US17238332
申请日:2021-04-23
Applicant: POSTECH Research and Business Development Foundation , Board of Regents, The University of Texas System
Inventor: Dong Sung KIM , Woojung Shin , Hyun Jung Kim , Jae Seung Yoon , Hyeon Beom Chong
Abstract: The present disclosure provides a three-dimensional cell culture method and a cell culture apparatus using the same. The cell culture method includes lowering, when culturing cells on at least one surface of a porous support, a concentration of a cell-secreted substance in a lower region of the other surface of the porous support. The cell culture apparatus includes: an upper chamber including an opening, porous support having at least one surface on which cells are cultured, and a cell culture space in which a culture medium is housed; a lower chamber including a space in which at least one upper chamber is disposed; and a device lowering a concentration of a cell-secreted substance in a lower region of the other surface of the porous support.
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公开(公告)号:US20210183074A1
公开(公告)日:2021-06-17
申请号:US17037399
申请日:2020-09-29
Inventor: Dai Jin KIM , Hye Min LEE
Abstract: Disclosed is a method of tracking multiple objects included in an image using a multi-object tracking apparatus including an integrated similarity neural network, the method including setting a tracking area in an input image, extracting at least one object candidate for a target object from the tracking area; extracting reference features for the target object, the object candidate, and the tracking area, selecting two of the target object, the object candidate, and the tracking area to evaluate similarity based on the reference features; allocating the object candidate to the target object on the basis of the evaluated similarity; and tracking the target object on the basis of a location of the allocated object candidate.
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公开(公告)号:US10958330B2
公开(公告)日:2021-03-23
申请号:US16727459
申请日:2019-12-26
Inventor: Jongbu Lim , Hyeongtaek Lee , Junil Choi , Sucheol Kim , Myungkwang Byun
IPC: H04B7/06 , H04L5/00 , H04L27/26 , H04B7/0408
Abstract: A communication system is provided. The communication system supports higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A first apparatus in a wireless communication system is provided. The apparatus includes an antenna array, at least one transceiver, and at least one processor. The transceiver is configured to transmit signals by using a beam set, and receive a signal for indicating at least one beam in the beam set from a second apparatus. The processor is configured to determine an auxiliary beam pair, based on the at least one beam. The transceiver is configured to transmit reference signals to the second apparatus by using the auxiliary beam pair, and receive feedback information relating to the auxiliary beam pair from the second apparatus. The at least one processor is configured to determine, based on the feedback information, a communication direction relating to the second apparatus.
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公开(公告)号:US20210079358A1
公开(公告)日:2021-03-18
申请号:US17005674
申请日:2020-08-28
Inventor: Kunyoo SHIN , Eunjee KIM , Sungjune JUNG
IPC: C12N5/071
Abstract: The present invention relates to a 3 dimensional mimetic tissue structure—“Assembloid” based on patient-derived multiple cell types to develop next generation organoid technology serving as a novel platform for new drug development and a disease model and a method of manufacturing the same, and more particularly, to a stem cell- or tumor cell-based 3D multicellular mimetic tissue structure manufactured by reconstituting epithelial or tumor cells with various cellular components of a microenvironment such as stromal cells, vascular cells, immune cells or muscle cells based on three-dimensional (3D) bioprinting, and a method of manufacturing the same. As the stem cell- or tumor cell-based 3D multicellular mimetic tissue structure containing the major factors of a tissue microenvironment, such as stromal cells, vascular cells, immune cells and muscle cells, designed according to the present invention is confirmed to mimic physiological and pathological characteristics of tissue in the body better than conventional organoids, normal and tumor assembloids may be used as a new platform for new drug development and a disease model. More specifically, together with 3D bioprinting technology, it is expected that in vitro bladder tissue and bladder tumor tissue are effectively used as a platform to develop precise and personalized therapeutic options for bladder related diseases including bladder cancer.
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公开(公告)号:US20200242456A1
公开(公告)日:2020-07-30
申请号:US16751503
申请日:2020-01-24
Inventor: Seokhyeong KANG , Yesung KANG , Sunghoon KIM , Yoonho PARK
Abstract: A neural network accelerator includes an operator that calculates a first operation result based on a first tiled input feature map and first tiled filter data, a quantizer that generates a quantization result by quantizing the first operation result based on a second bit width extended compared with a first bit width of the first tiled input feature map, a compressor that generates a partial sum by compressing the quantization result, and a decompressor that generates a second operation result by decompressing the partial sum, the operator calculates a third operation result based on a second tiled input feature map, second tiled filter data, and the second operation result, and an output feature map is generated based on the third operation result.
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公开(公告)号:US20200227835A1
公开(公告)日:2020-07-16
申请号:US16827967
申请日:2020-03-24
Inventor: Jong Min KIM , Dong Pil PARK , Yun Seok OH , Won Bin HONG
Abstract: An antenna structure includes an antenna device including a dielectric layer and a plurality of radiation patterns on an upper surface of the dielectric layer, and a flexible circuit board including a feeding wiring electrically connected to the radiation patterns. The feeding wiring includes a plurality of individual wirings, each of which electrically connected to each of the radiation patterns, and lengths of neighboring individual wirings included in at least one pair from the plurality of individual wirings are different from each other.
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420.
公开(公告)号:US20200220654A1
公开(公告)日:2020-07-09
申请号:US16734913
申请日:2020-01-06
Inventor: Min JANG , Kyeongcheol YANG , Daeyeol YANG , Jiwon PARK , Hongsil JEONG
Abstract: A method and a device for transmitting a signal by using a polar code are provided. The method includes generating a first codeword by applying the polar code to an input signal, dividing the first codeword into a plurality of partial vectors, allocating a shaping bit to the input signal when at least one of the plurality of partial vectors does not satisfy a preset Hamming weight condition, generating a second codeword by applying the polar code to the input signal to which the shaping bit is allocated, and transmitting a signal based on the second codeword.
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