LABELING METHOD FOR NUCLEIC ACID
    42.
    发明申请

    公开(公告)号:US20200308635A1

    公开(公告)日:2020-10-01

    申请号:US16798704

    申请日:2020-02-24

    摘要: Provided is a labeling method for nucleic acid including a reaction step for hybridizing a nucleic acid probe that has a nucleotide sequence complementary to that of a nucleic acid to be labeled and contains a reactive nucleobase derivative incorporated at a position complementary to that of a target nucleobase as a target of labeling in the nucleic acid to be labeled, to the nucleic acid to be labeled; a transferring step for transferring a transfer group contained in the reactive nucleobase derivative to the nucleotide residue containing the target nucleobase in the nucleic acid to be labeled; and a labeling step for labeling the transfer group transferred to the nucleotide residue with a radioactive material.

    METHOD FOR PRODUCING NONAQUEOUS COMPOSITION FOR EXTERNAL USE ON SKIN

    公开(公告)号:US20200306148A1

    公开(公告)日:2020-10-01

    申请号:US16753396

    申请日:2018-10-05

    摘要: A method for producing a nonaqueous composition for external use on the skin including a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase, the method including the steps of: dissolving a surfactant in an oil phase to obtain a surfactant solution; mixing the obtained surfactant solution with a strongly hydrophilic amphiphilic solid active ingredient to obtain a suspension; and allowing the obtained suspension to stand still to obtain a transparent composition. Unlike conventional methods for preparing S/O formulations, the strongly hydrophilic amphiphilic solid active ingredient can be solubilized in an oil phase without the process of emulsification and freeze drying.

    Optical member, light guiding member, and method for producing optical member

    公开(公告)号:US10739506B2

    公开(公告)日:2020-08-11

    申请号:US15576737

    申请日:2016-04-22

    摘要: The purpose of the present invention is to provide an optical member and the like which enable suppression of diffusion of stray light due to a pigment even when the optical member and the like are used adjacent to a light guiding part through which incident light is transmitted. The optical member is configured to be used adjacent to the light guiding part through which the incident light is transmitted and to attenuate the incident light. The optical member has a dispersed carbon particle part that is formed as a result of dispersion of carbon particles in a particular region in a silicone resin. The carbon particles are stray light diffusion suppressing particles for suppressing the intensity of light being incident onto the carbon particles and diffused.