公开(公告)号：US20130287279A1

公开(公告)日：2013-10-31

申请号：US13978591

申请日：2011-12-29

申请人： Ewald Roessl ,  Thomas Koehler ,  Axel Thran

发明人： Ewald Roessl ,  Thomas Koehler ,  Axel Thran

IPC分类号： G06T11/00

CPC分类号： G06T11/003 ,  G06T11/006 ,  G06T2211/408 ,  G06T2211/424

摘要： The invention relates to an imaging system (30) for imaging an object. A projection data providing unit (31) provides acquired spectral projection data of an object comprising at least two components, and a reconstruction unit (10) iteratively reconstructs at least two final component images of the object by performing several iteration steps, in which at least two intermediate component images are updated based on the acquired spectral projection data and a penalty term, which is indicative of the correlated noise between the at least two intermediate component images. Since the at least two intermediate component images are updated based on the acquired spectral projection data and a penalty term, which is indicative of the correlated noise, correlated noise is penalized during the iterative reconstruction. The finally resulting component images of the object are therefore less corrupted by correlated noise and have an improved image quality.

摘要翻译： 本发明涉及一种用于对物体成像的成像系统（30）。 投影数据提供单元（31）提供包括至少两个分量的对象的获取的光谱投影数据，并且重建单元（10）通过执行几个迭代步骤来迭代地重构对象的至少两个最终分量图像，其中至少 基于所获取的光谱投影数据和惩罚项来更新两个中间分量图像，所述惩罚项指示所述至少两个中间分量图像之间的相关噪声。 由于基于所获取的频谱投影数据和指示相关噪声的罚分项来更新至少两个中间分量图像，所以在迭代重建期间相关噪声被惩罚。 因此，最终产生的对象的分量图像被相关噪声较少损坏并且具有改善的图像质量。

公开(公告)号：US08338791B2

公开(公告)日：2012-12-25

申请号：US12665558

申请日：2008-05-23

申请人： Roland Proksa ,  Jens-Peter Schlomka ,  Ewald Roessl ,  Tuvia Liran ,  Aviv Marks

发明人： Roland Proksa ,  Jens-Peter Schlomka ,  Ewald Roessl ,  Tuvia Liran ,  Aviv Marks

IPC分类号： G01J5/02

CPC分类号： G01T1/171

摘要： An apparatus includes a local minimum identifier (408) that identifies a local minimum between overlapping pulses in a signal, wherein the pulses have amplitudes that are indicative of the energy of successively detected photons from a multi-energetic radiation beam by a radiation sensitive detector, and a pulse pile-up error corrector (232) that corrects, based on the local minimum, for a pulse pile-up energy-discrimination error when energy-discriminating the pulses using at least two thresholds corresponding to different energy levels. This technique may reduce spectral error when counting photons at a high count rate.

摘要翻译： 一种装置包括识别信号中重叠脉冲之间的局部最小值的局部最小标识符（408），其中脉冲具有指示由辐射敏感检测器从多能辐射束连续检测到的光子的能量的幅度， 以及脉冲堆积误差校正器（232），其基于局部最小值来校正针对对应于不同能级的至少两个阈值对脉冲进行能量鉴别的脉冲堆积能量鉴别误差。 当以高计数率计数光子时，该技术可能降低光谱误差。

公开(公告)号：US20120307966A1

公开(公告)日：2012-12-06

申请号：US13514383

申请日：2010-12-03

申请人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sabastian Siegmund Schusser ,  Thomas Koehler

发明人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sabastian Siegmund Schusser ,  Thomas Koehler

IPC分类号： G01N23/04

CPC分类号： A61B6/00 ,  A61B6/032 ,  A61B6/4021 ,  A61B6/4092 ,  A61B6/4291 ,  A61B6/484

摘要： The present invention relates to X-ray image acquisition technology in general. Employing phase-contrast imaging for X-ray image acquisition may significantly enhance the quality and information content of images acquired. However, phase-contrast information may only be obtainable in a small detector region, possibly being too small for a sufficient field of rotation view for specialized X-ray imaging applications. Accordingly, an apparatus for phase-contrast imaging is provided that may allow the acquisition of an enlarged field of view. According to the present invention an apparatus (1) for phase-contrast imaging is provided, comprising an X-ray source (2), an X-ray detector (12) element having a detector size, a beam splitter grating (8) and an analyzer grating (10). An object (6) is arrangeable between the X-ray source (2) and the X-ray detector (12). The beam splitter grating (8) and the analyzer grating (10) are arrangeable between the X-ray source (2) and the X-ray detector (12). X-ray source (2), the beam splitter grating (8), the analyzer grating (10) and the X-ray detector (12) are operatively coupled such that a phase-contrast image of the object (6) is obtainable. The apparatus (1) is adapted for acquiring a phase-contrast image having a field of view larger than the detector size. The X-ray detector element (12) is displaceable and by the displacement of the X-ray detector (12) a phase-contrast image of the field of view is obtainable.

摘要翻译： 本发明一般涉及X射线图像获取技术。 采用X射线图像获取的相位对比成像可显着提高获取图像的质量和信息内容。 然而，相位对比度信息只能在小的检测器区域中获得，对于专门的X射线成像应用，可能对于足够的旋转视场来说太小。 因此，提供了一种用于相位对比成像的装置，其可以允许获取放大的视场。 根据本发明，提供了一种用于相位对比成像的装置（1），包括具有检测器尺寸的X射线源（2），X射线检测器（12）元件，分束器光栅（8）和 分析器光栅（10）。 物体（6）可布置在X射线源（2）和X射线检测器（12）之间。 分束器光栅（8）和分析器光栅（10）可布置在X射线源（2）和X射线检测器（12）之间。 X射线源（2），分束器光栅（8），分析器光栅（10）和X射线检测器（12）可操作地耦合，使得可以获得物体（6）的相位对比度图像。 装置（1）适于获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件（12）可移动，并且通过X射线检测器（12）的移位，可以获得视场的相位对比图像。

公开(公告)号：US20120250823A1

公开(公告)日：2012-10-04

申请号：US13514166

申请日：2010-12-08

申请人： Gereon Vogtmeier ,  Klaus Juergen Engel ,  Dieter Geller ,  Thomas Koehler ,  Ewald Roessl

发明人： Gereon Vogtmeier ,  Klaus Juergen Engel ,  Dieter Geller ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： A61B6/02

CPC分类号： A61B6/4291 ,  A61B6/4092 ,  A61B6/484 ,  A61B6/583 ,  G21K2207/005

摘要： The present invention relates to an X-ray imaging system and a method for differential phase—contrast imaging of an object. To improve calibration of differential phase—contrast imaging systems and the alignment of the gratings an X-ray imaging system is provided that comprises an X-ray emitting arrangement providing at least partially coherent X-ray radiation and an X-ray detection arrangement comprising a phase-shift diffraction grating, a phase analyzer grating, and an X-ray image detector, all arranged along an optical axis. For stepping, the gratings and/or the X-ray emitting arrangement are provided with at least two actuators arranged opposite to each other with reference to the optical axis. For calibration, calibration projections are acquired without an object, wherein, the emitted X-ray radiation or one of the gratings is stepwise displaced with a calibration displacement value. For examination, measurement projections are acquired with an object, wherein the emitted X-ray radiation or one of the gratings is stepwise displaced with a measurement, a calibration projection is associated to each of the measurement projections by registering the latter with the calibration projections.

摘要翻译： 本发明涉及一种用于物体的差分相位对比成像的X射线成像系统和方法。 为了改进差分相位对比成像系统的校准和光栅的对准，提供了一种X射线成像系统，其包括提供至少部分相干X射线辐射的X射线发射装置和包括 相移衍射光栅，相位分析器光栅和X射线图像检测器，均沿着光轴排列。 对于步进，光栅和/或X射线发射装置设置有相对于光轴彼此相对布置的至少两个致动器。 对于校准，在没有物体的情况下获取校准投影，其中，所发射的X射线辐射或其中一个光栅以校准位移值逐步位移。 为了进行检查，用物体获取测量投影，其中所发射的X射线辐射或其中一个光栅通过测量逐步移位，通过将校准投影与校准投影配准，将校准投影与每个测量投影相关联。

公开(公告)号：US08213566B2

公开(公告)日：2012-07-03

申请号：US13000371

申请日：2009-06-22

申请人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

发明人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

IPC分类号： A61B6/00 ,  G06K9/00

CPC分类号： G01N23/087 ,  A61B5/4869 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482

摘要： An imaging system including a radiation source (110) that emits poly-chromatic radiation that traverses an examination region and a detector (116) that detects radiation traversing the examination region and produces a signal indicative of the energy of a detected photon. The system further includes an energy discriminator (122) that energy resolves the signal based on a plurality of different energy thresholds, wherein at least two of the energy thresholds have values corresponding to at least two different K-edge energies of two different elements in a mixture disposed in the examination region. The system also includes a signal decomposer (132) that decomposes the energy-resolved signal into at least a multi K-edge component representing the at least two different K-edge energies. In one instance, a stoichiometric ratio of the two different elements in the contrast agent is known and substantially constant.

摘要翻译： 一种成像系统，包括发射穿过检查区域的多色辐射的辐射源（110）和检测穿过检查区域的辐射的检测器（116），并产生指示检测到的光子的能量的信号。 所述系统还包括能量鉴别器（122），所述能量鉴别器（122）能量基于多个不同的能量阈值来解析所述信号，其中所述能量阈值中的至少两个具有对应于两个不同元素的至少两个不同K边能量的值 混合物置于检查区域。 该系统还包括信号分解器（132），其将能量分辨信号分解成代表至少两个不同的K边缘能量的至少多个K边缘分量。 在一种情况下，造影剂中两种不同元素的化学计量比是已知的并且基本上是恒定的。

公开(公告)号：US20120057677A1

公开(公告)日：2012-03-08

申请号：US13319196

申请日：2010-06-09

申请人： Gereon Vogtmeier ,  Klaus Juergen Engel ,  Thomas Koehler ,  Ewald Roessl

发明人： Gereon Vogtmeier ,  Klaus Juergen Engel ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： G21K1/06 ,  B29D11/00 ,  G02B5/18

CPC分类号： G02B5/1857 ,  A61B6/484 ,  G21K2201/06 ,  G21K2207/005

摘要： The present invention relates to phase-contrast imaging which visualizes the phase information of coherent radiation passing a scanned object. Focused gratings are used which reduce the creation of trapezoid profile in a projection with a particular angle to the optical axis. A laser supported method is used in combination with a dedicating etching process for creating such focused grating structures.

摘要翻译： 本发明涉及相位成像，其可视化通过扫描对象的相干辐射的相位信息。 使用聚焦光栅，其减小了与光轴具有特定角度的投影中的梯形轮廓的产生。 激光支持的方法与用于产生这种聚焦光栅结构的专用蚀刻工艺结合使用。

公开(公告)号：US08055050B2

公开(公告)日：2011-11-08

申请号：US12377297

申请日：2007-07-23

申请人： Ewald Roessl ,  Udo Van Stevendaal

发明人： Ewald Roessl ,  Udo Van Stevendaal

IPC分类号： G06K9/00 ,  A61B6/03

CPC分类号： G06T11/005 ,  A61B6/027 ,  G06T2211/412

摘要： An imaging system includes an energy resolving detector (20) which generates data indicative of detected radiation having at least first and second energies. The system also includes an energy pre-processor (24), a motion calculator (26), and a reconstructor (22). In one embodiment, the apparatus uses a k-edge imaging technique to perform a motion compensated reconstruction of projection data indicative of an object under examination.

摘要翻译： 成像系统包括能量分辨检测器（20），其产生指示具有至少第一和第二能量的检测到的辐射的数据。 该系统还包括能量预处理器（24），运动计算器（26）和重构器（22）。 在一个实施例中，该装置使用k边缘成像技术来执行指示被检查对象的投影数据的运动补偿重建。

公开(公告)号：US20110096905A1

公开(公告)日：2011-04-28

申请号：US13000371

申请日：2009-06-22

申请人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

发明人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

IPC分类号： G01N23/04

CPC分类号： G01N23/087 ,  A61B5/4869 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482

摘要： An imaging system including a radiation source (110) that emits poly-chromatic radiation that traverses an examination region and a detector (116) that detects radiation traversing the examination region and produces a signal indicative of the energy of a detected photon. The system further includes an energy discriminator (122) that energy resolves the signal based on a plurality of different energy thresholds, wherein at least two of the energy thresholds have values corresponding to at least two different K-edge energies of two different elements in a mixture disposed in the examination region. The system also includes a signal decomposer (132) that decomposes the energy-resolved signal into at least a multi K-edge component representing the at least two different K-edge energies. In one instance, a stoichiometric ratio of the two different elements in the contrast agent is known and substantially constant.

摘要翻译： 一种成像系统，包括发射穿过检查区域的多色辐射的辐射源（110）和检测穿过检查区域的辐射的检测器（116），并产生指示检测到的光子的能量的信号。 所述系统还包括能量鉴别器（122），所述能量鉴别器（122）能量基于多个不同的能量阈值来解析所述信号，其中所述能量阈值中的至少两个具有对应于两个不同元素的至少两个不同K边能量的值 混合物置于检查区域。 该系统还包括信号分解器（132），其将能量分辨信号分解成代表至少两个不同的K边缘能量的至少多个K边缘分量。 在一种情况下，造影剂中两种不同元素的化学计量比是已知的并且基本上是恒定的。

公开(公告)号：US20110012014A1

公开(公告)日：2011-01-20

申请号：US12934661

申请日：2009-03-20

申请人： Amir Livne ,  Naor Wainer ,  Jens-Peter Schlomka ,  Ewald Roessl ,  Roland Proksa

发明人： Amir Livne ,  Naor Wainer ,  Jens-Peter Schlomka ,  Ewald Roessl ,  Roland Proksa

IPC分类号： G01D18/00

CPC分类号： G01T7/005 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/4441 ,  A61B6/482 ,  A61B6/585 ,  G01N2223/3037 ,  G01T1/1647

摘要： A method includes detecting radiation that traverses a material having a known spectral characteristic with a radiation sensitive detector pixel that outputs a signal indicative of the detected radiation and determining a mapping between the output signal and the spectral characteristic. The method further includes determining an energy of a photon detected by the radiation sensitive detector pixel based on a corresponding output of the radiation sensitive detector pixel and the mapping.

摘要翻译： 一种方法包括利用辐射敏感检测器像素检测穿过具有已知光谱特性的材料的辐射，所述辐射敏感检测器像素输出指示检测到的辐射的信号并确定输出信号和光谱特性之间的映射。 该方法还包括基于辐射敏感检测器像素的对应输出和映射来确定由辐射敏感检测器像素检测到的光子的能量。

公开(公告)号：US07822169B2

公开(公告)日：2010-10-26

申请号：US12293845

申请日：2007-03-14

申请人： Ewald Roessl ,  Andy Ziegler

发明人： Ewald Roessl ,  Andy Ziegler

IPC分类号： A61B6/00

CPC分类号： G06T5/50 ,  A61B6/027 ,  A61B6/583

摘要： It is described a method for reducing noise of X-ray attenuation data related to a first and second spectral X-ray data acquisition. The method comprises the steps of (a) acquiring data representing the X-ray attenuation behavior of a region of interest, (b) determining a first and a second attenuation-base line integral for the first and the second X-ray acquisition, respectively, and (c) calculating expected first and second signal to noise ratios for the first and the second attenuation-base line integral based on given signal to noise ratios for the first and second spectral X-ray data acquisition, respectively. The method further comprises the steps of (d) repeating the above mentioned steps of determining the attenuation-base line integrals and calculating the expected signal to noise ratios for a further first spectral X-ray data acquisition and (e) selecting improved spectral X-ray data acquisitions in order to enhance the overall signal to noise ratio of a final X-ray image.

摘要翻译： 描述了一种用于降低与第一和第二光谱X射线数据采集相关的X射线衰减数据的噪声的方法。 该方法包括以下步骤：（a）获取表示感兴趣区域的X射线衰减特性的数据，（b）分别确定第一和第二X射线采集的第一和第二衰减基线积分 ，以及（c）分别基于用于第一和第二频谱X射线数据采集的给定信噪比来计算第一和第二衰减基线积分的期望的第一和第二信噪比。 该方法还包括以下步骤：（d）重复上述步骤以确定衰减基线积分并计算进一步的第一光谱X射线数据采集的预期信噪比，以及（e）选择改进的光谱X- 以提高最终X射线图像的整体信噪比。