公开(公告)号：US07060948B2

公开(公告)日：2006-06-13

申请号：US10307694

申请日：2002-12-02

Applicant: Dong-il Cho ,  Dae-sung Yoon ,  Young-sun Lee ,  Dong-hoon Yi ,  Geun-bae Lim

Inventor： Dong-il Cho ,  Dae-sung Yoon ,  Young-sun Lee ,  Dong-hoon Yi ,  Geun-bae Lim

IPC: H05B1/02

CPC classification number: B01L7/525 ,  B01L2200/147 ,  G05D23/1934 ,  Y10T307/469

Abstract: Provided are a temperature control method and apparatus for driving a polymerize chain reaction (PCR) chip. In the temperature control apparatus, which is for a polymerize chain reaction chip, PCR chips receive electric power from the outside and generating heat to maintain a predetermined temperature and for outputting actual temperature information to the outside. electric power supply units supply electric power to the PCR chips according to input control signals, and a controller generates the control signals based on control information including pre-established control temperature and control time information and the actual temperature information supplied from the PCR chips in order to supply the control signals to the electric power supply units. In the present invention, it is possible to examine various kinds of DNA at the same time because the temperature control apparatus controls the temperatures of DNA samples at the same time.

Abstract translation: 提供了用于驱动聚合链式反应（PCR）芯片的温度控制方法和装置。 在用于聚合链式反应芯片的温度控制装置中，PCR芯片从外部接收电力并产生热量以保持预定温度并将实际温度信息输出到外部。 电源单元根据输入控制信号向PCR芯片提供电力，并且控制器基于包括预先建立的控制温度和控制时间信息的控制信息以及从PCR芯片提供的实际温度信息按顺序产生控制信号 以将控制信号提供给电力供应单元。 在本发明中，可以同时检测各种DNA，因为温度控制装置同时控制DNA样品的温度。

公开(公告)号：US20050208579A1

公开(公告)日：2005-09-22

申请号：US11134984

申请日：2005-05-23

Applicant: Jun-hoe Cha ,  Young Choi ,  Jung-im Han ,  Geun-bae Lim

Inventor： Jun-hoe Cha ,  Young Choi ,  Jung-im Han ,  Geun-bae Lim

IPC: G01N33/53 ,  C07D409/12 ,  C07D409/14 ,  C08G61/12 ,  C25D9/02 ,  G01N27/12 ,  G01N27/30 ,  G01N27/327 ,  G01N27/333 ,  G01N27/416 ,  G01N27/48 ,  G01N33/543 ,  G01N33/545 ,  G01N33/566 ,  H01B1/12 ,  C12Q1/68 ,  B05D5/12 ,  C08G69/08 ,  C08G73/10 ,  C08G75/00 ,  C08G75/04 ,  G03G15/00

CPC classification number: G01N33/545 ,  C08G61/126 ,  G01N33/5438 ,  H01B1/127

Abstract: A novel electrically conductive polymer, a sensor using the electrically conductive polymer, and a method for detecting a target molecule that hybridizes to a probe, using the sensor, are provided. The electrically conductive polymer has the following formula: where m is 1, 2, or 3; R is a hydroxysuccinimidyl group, a hydroxyphthalimidyl group, or a pentafluorophenolyl group; and n is zero or an integer.

Abstract translation: 提供了一种新型导电聚合物，使用导电聚合物的传感器，以及使用传感器检测与探针杂交的靶分子的方法。 导电聚合物具有下式：其中m为1,2或3; R是羟基琥珀酰亚胺基，羟基邻苯二甲酰亚氨基或五氟苯基; 并且n为零或整数。

公开(公告)号：US20050199917A1

公开(公告)日：2005-09-15

申请号：US11057642

申请日：2005-02-14

Applicant: Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

Inventor： Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

IPC: G01N27/327 ,  C12Q1/68 ,  G01N27/414 ,  G01N33/487 ,  H01L29/08

CPC classification number: G01N27/4145

Abstract: There is provided a biomolecule FET enhancing a sensitivity. The biomolecule FET includes a substrate, first and second impurity regions formed on both sides of the substrate, and doped with impurities of a polarity opposite to that of the substrate, a gate formed on the substrate and being in contact with the first and second impurity regions, and a probe biomolecule attached to the gate. A region of the gate adjacent to the first impurity region is wider than a region thereof adjacent to the second impurity region. A density of the probe biomolecule attached to the surface of the gate is increased, and when detecting a level of hybridization of the probe biomolecule and the target biomolecule, its sensitivity is improved.

Abstract translation: 提供了提高灵敏度的生物分子FET。 生物分子FET包括基板，形成在基板两侧的第一和第二杂质区，并且掺杂极性与基板极性相反的杂质;形成在基板上并与第一和第二杂质接触的栅极 区域，以及连接到门的探针生物分子。 与第一杂质区相邻的栅极的区域比与第二杂质区相邻的区域宽。 附着在栅极表面的探针生物分子的密度增加，并且当检测到探针生物分子和靶生物分子的杂交水平时，其灵敏度得到改善。