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公开(公告)号:US06485716B1
公开(公告)日:2002-11-26
申请号:US09971876
申请日:2001-10-05
申请人: Lin Fei , Suman Chopra , Eric Guenin , Peter Hilliard, Jr. , Jairajh Mattai , Neeta Patel
发明人: Lin Fei , Suman Chopra , Eric Guenin , Peter Hilliard, Jr. , Jairajh Mattai , Neeta Patel
IPC分类号: A61K732
CPC分类号: A61K8/894 , A61K8/042 , A61K8/046 , A61K8/26 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/375 , A61K8/891 , A61K2800/262 , A61Q15/00
摘要: The invention is a clear, elastomer-free, gel composition comprising: (a) 0.1-25 weight % of an antiperspirant active having a low metal to chloride ratio in the range of 0.9-1.3: 1; (b) 9-23.95 weight % of one or more volatile silicones having a flash point of 100 degrees C or less; (c) 0.05-0.5 weight % of a silicone surfactant having an HLB value≦8; (d) 30-70 weight % water; (e) 0-50 weight % selected water soluble organic solvents; and (f) 0-10 weight % of an emollient; wherein the composition is a liquid gel having a viscosity in the range of 5-50,000 centipoise and a ratio of oil phase to water phase in the range of 10:90 to 24:76.
摘要翻译: 本发明是一种透明的,无弹性体的凝胶组合物,其包含:(a)0.1至25重量%的低金属与氯化物之比在0.9-1.3:1范围内的止汗活性剂; (b)9-23.95重量%的闪点为100℃以下的一种或多种挥发性有机硅; (c)0.05-0.5重量%的具有HLB值<= 8的硅氧烷表面活性剂; (d)30-70重量%的水; (e)0-50重量%选择的水溶性有机溶剂; 和(f)0-10重量%的润肤剂; 其中所述组合物是粘度在5-50,000厘泊范围内的液体凝胶,油相与水相的比例在10:90至24:76的范围内。
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公开(公告)号:US06403069B1
公开(公告)日:2002-06-11
申请号:US09693248
申请日:2000-10-20
申请人: Suman Chopra , Jairajh Mattai , Lin Fei , Eric Guenin , Xiaozhong Tang
发明人: Suman Chopra , Jairajh Mattai , Lin Fei , Eric Guenin , Xiaozhong Tang
IPC分类号: A61K732
摘要: A clear antiperspirant and/or deodorant composition is disclosed in the form of an emulsion having a refractive index less than 1.42 and comprising: (a) 25-70% of an external phase comprising: (i) 0.1-10%, on an actives basis, of at least one elastomer which is a dimethicone/vinyldimethicone crosspolymer composition made by reacting a polymethylhydrogensiloxane with an alpha, omega-divinylpolydimethyl siloxane for which the dimethicone/vinyl-dimethicone crosspolymer composition is used at a concentration of 4-10% in cyclomethicone, has a refractive index in the range of 1.392-1.402 at 25 degrees C and a viscosity in the range of 0.013-1×104 Pascal seconds; (ii) 0.1-5% of a silicone copolyol having an HLB value ≦8; (iii) 0.1-68% of a volatile silicone selected in an amount to complete the external phase; (iv) 0-10% of a cosurfactant or emulsifier having an HLB value in the range of 1-15; (v) 0-5% of a non-volatile silicone; and (b) 30-75% of an internal phase which is made with: (i) 7-25% (on an anhydrous actives basis (excluding the waters of hydration) of an antiperspirant active; (ii) 0-10% ethanol; (iii) additional water as required to adjust the refractive index; (iv) 0-5% of an antimicrobial agent; and (v) 0-5% of an ionizable salt; wherein the conductance of a water droplet applied to the surface of a thin film of the antiperspirant and/or deodorant composition is at least 250 micro Siemens/cm/ml as measured by a fixed geometry test at a loading of at least 7% by weight level of antiperspirant active.
摘要翻译: 透明止汗剂和/或除臭剂组合物以折射率小于1.42的乳液的形式公开,并包含:(a)25-70%的外相,其包含:(i)0.1-10%的活性物质 基于至少一种弹性体,其是通过使聚甲基氢硅氧烷与α,ω-二乙烯基聚二甲基硅氧烷反应制备的聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物组合物,其中在聚甲基硅氧烷中以4-10%的浓度使用聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物组合物 在25℃下的折射率在1.392-1.402的范围内,粘度在0.013-1×104帕斯卡秒的范围内; (ii)具有HLB值<= 8的0.1-5%的硅氧烷共聚多元醇; (iii)以完成外相的量选择0.1-68%的挥发性硅氧烷; (iv)0-10%HLB值在1-15范围内的辅助表面活性剂或乳化剂; (v)0-5%的非挥发性硅酮; 和(b)30-75%的内相,其由以下制备:(i)7-25%(基于无水活性物质(不包括水合水合))止汗活性物质;(ii)0-10%乙醇 ;(iii)调整折射率所需的额外的水;(iv)0-5%的抗微生物剂;和(v)0-5%的可电离盐;其中施加到表面的水滴的电导率 的止汗剂和/或除臭剂组合物的薄膜是至少250微西门子/厘米/毫升,通过固定几何测试在至少7重量%的止汗活性剂的负载下测量。
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公开(公告)号:US09308399B2
公开(公告)日:2016-04-12
申请号:US13582115
申请日:2010-03-11
IPC分类号: A61Q11/00 , A61K8/22 , A61K8/25 , A61K6/00 , A61K33/40 , A61Q11/02 , A61K8/31 , A61K8/49 , A61K8/81 , A61K8/891
CPC分类号: A61Q11/00 , A61K8/22 , A61K8/31 , A61K8/4913 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要: A tooth whitening composition for whitening a surface of a tooth, the composition comprising a mixture of a whitening agent comprising an aqueous peroxide, a hydrophobic polymer carrier for adhering the tooth whitening composition to a tooth surface and at least one adhesion enhancing agent.
摘要翻译: 一种用于使牙齿表面美白的牙齿美白组合物,所述组合物包含含有过氧化氢的增白剂,用于将牙齿增白组合物粘附到牙齿表面的疏水聚合物载体和至少一种粘合增强剂的混合物。
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公开(公告)号:US09271565B2
公开(公告)日:2016-03-01
申请号:US13812423
申请日:2010-07-30
申请人: Sarita Mello , Madhusudan Patel , Sharon Kennedy , Thomas Boyd , Evangelia S. Arvanitidou , James R. Brown , Suman Chopra
发明人: Sarita Mello , Madhusudan Patel , Sharon Kennedy , Thomas Boyd , Evangelia S. Arvanitidou , James R. Brown , Suman Chopra
CPC分类号: A46B11/00 , A46B11/001 , A46B2200/1066 , A61K8/34 , A61K8/4926 , A61K2800/244 , A61K2800/87 , A61Q11/00
摘要: Disclosed are compositions suitable for use with an oral care implement. The compositions provide improved sensory appeal, and comparable reduction in volatile sulfur compounds and antibacterial activity to advanced formula toothpaste formulations. The compositions include a high percentage of antibacterial agent and flavoring, when compared to conventional toothpastes, and some mouth washes formulations, such that only minor amounts of the composition can be delivered to the oral care implement to provide improved reduction in volatile sulfur compounds, antibacterial efficacy, and optionally a cooling sensation.
摘要翻译: 公开了适用于口腔护理器具的组合物。 组合物提供改善的感官吸引力,以及挥发性硫化合物的相当的降低和对先进配方牙膏制剂的抗菌活性。 当与常规牙膏相比时,组合物包含高百分比的抗菌剂和调味剂,以及一些漱口剂制剂,使得只有少量的组合物可以递送到口腔护理器具以提供挥发性硫化合物的改善的减少,抗菌剂 功效和任选的冷却感。
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公开(公告)号:US20130287710A1
公开(公告)日:2013-10-31
申请号:US13997430
申请日:2011-06-02
CPC分类号: A61K8/8182 , A61K8/0216 , A61K8/22 , A61K8/24 , A61K8/345 , A61K8/463 , A61K8/8176 , A61K8/86 , A61K8/90 , A61K2800/28 , A61K2800/31 , A61K2800/52 , A61K2800/57 , A61K2800/87 , A61Q11/00
摘要: Oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with an ethylene oxide-propylene oxide block copolymer. Some embodiments further comprise a calcium abrasive, e.g. calcium pyrophosphate or calcium carbonate, and some may have less than 3% water.
摘要翻译: 包含与过氧化氢配合的交联聚乙烯吡咯烷酮与环氧乙烷 - 环氧丙烷嵌段共聚物的口腔护理组合物。 一些实施方案还包括钙磨料,例如。 焦磷酸钙或碳酸钙,一些可能具有少于3%的水。
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公开(公告)号:US20090202456A1
公开(公告)日:2009-08-13
申请号:US12058387
申请日:2008-03-28
申请人: Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人: Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
IPC分类号: A61K8/44 , A61K31/195 , A61Q11/00
CPC分类号: A61K8/44 , A61K8/463 , A61K8/55 , A61K8/8164 , A61K31/198 , A61Q11/00
摘要: The invention relates to novel arginine salts, compositions comprising them, and their uses.
摘要翻译: 本发明涉及新颖的精氨酸盐,包含它们的组合物及其用途。
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公开(公告)号:US20090202455A1
公开(公告)日:2009-08-13
申请号:US12058360
申请日:2008-03-28
申请人: Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人: Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
摘要: This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
摘要翻译: 本发明涉及口腔护理组合物,其包含有效量的碱性氨基酸盐,该盐在无缓冲溶液中的pH值小于约7.5; 有效量的可溶性氟化物盐; 以及具有小于约7.5的无缓冲溶液中的pH的颗粒材料; 以及使用和制备这种组合物的方法。
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公开(公告)号:US20080274065A1
公开(公告)日:2008-11-06
申请号:US12028782
申请日:2008-02-08
申请人: Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人: Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
CPC分类号: A61K8/25 , A61K8/44 , A61K2800/28 , A61K2800/412 , A61K2800/88 , A61Q11/00
摘要: The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.
摘要翻译: 本发明包括清洁口腔表面,维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触,使口腔表面与定期的口腔护理维持组合物每月至少一次接触,其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。
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公开(公告)号:US20050281757A1
公开(公告)日:2005-12-22
申请号:US10870848
申请日:2004-06-17
申请人: Sayed Ibrahim , Suman Chopra , Michael Prencipe
发明人: Sayed Ibrahim , Suman Chopra , Michael Prencipe
CPC分类号: A61K8/0208 , A61K8/8135 , A61K8/8176 , A61K8/8182 , A61Q11/00
摘要: A composition for delivery of an oral care substance to a dental surface upon application of the composition thereto is a flexible film comprising the oral care substance dispersed in a film-forming effective amount of a polymeric matrix having a hydrophilic component, e.g., vinylpyrrolidone (VP), and a hydrophobic component, e.g., vinyl acetate (VA), in a weight ratio selected such that the film is substantially dissolvable in saliva in a period of time effective for delivery of the oral care substance. The polymeric matrix illustratively comprises a poly(VP/VA) copolymer having a VP/VA weight ratio of about 90:10 to about 10:90.
摘要翻译: 用于将组合物施用于口腔护理物质到牙齿表面的组合物是包含分散在成膜有效量的具有亲水组分的聚合物基质例如乙烯基吡咯烷酮(VP)的柔性膜 )和疏水组分,例如乙酸乙烯酯(VA),其选择的重量比使得该膜在有效递送口腔护理物质的时间段内基本上可溶于唾液中。 聚合物基体示例性地包含VP / VA重量比为约90:10至约10:90的聚(VP / VA)共聚物。
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公开(公告)号:US20050158261A1
公开(公告)日:2005-07-21
申请号:US11080913
申请日:2005-03-15
申请人: Xiaozhong Tang , Lin Fei , Suman Chopra , Peter Hilliard
发明人: Xiaozhong Tang , Lin Fei , Suman Chopra , Peter Hilliard
IPC分类号: A61K8/04 , A61K8/26 , A61K8/44 , A61K8/892 , A61K8/894 , A61K8/895 , A61Q15/00 , C07F5/06 , A61K7/32 , A61K7/38
摘要: A zirconium-free aluminum salt which: (a) has an aluminum to chloride molar ratio in the range of 0.5-2.5:1; (b) comprises a nitrogen containing buffering material in an amount such that the ratio of nitrogen containing material to aluminum is the range of 0.05-0.26:1, and which nitrogen containing material is selected from the group consisting of a nitrogen containing buffering material of formula where n is a number in the range of 1-20, and each of R1, R2, and R3 is independently selected from the group consisting of hydrogen, methyl and ethyl; and (c) the salt has a pH in the range of 2-4 at a concentration of 15%; wherein the salt is free of any other halide scavenging material and has a value of at least 0.50 for the ratio calculated as: area of Peak 5/total area under Peak 2+Peak 3+Peak 4+Peak 5.
摘要翻译: 一种无锆铝盐,其:(a)铝与氯的摩尔比在0.5-2.5:1的范围内; (b)包括含氮缓冲材料,其含量使得含氮材料与铝的比例为0.05-0.26:1,并且所述含氮材料选自含氮缓冲材料的氮 其中n是1-20范围内的数字,并且R 1,R 2和R 3 3中的每一个独立地被选择 由氢,甲基和乙基组成的组; 和(c)盐的浓度为15%时的pH在2-4范围内; 其中盐不含任何其它卤化物清除材料,并且对于以下计算的比率,其值为至少0.50:峰5的面积/峰2 +峰3 +峰4 +峰5之间的总面积。
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