High efficacy liquid gel product
    41.
    发明授权
    High efficacy liquid gel product 失效
    高效液体凝胶产品

    公开(公告)号:US06485716B1

    公开(公告)日:2002-11-26

    申请号:US09971876

    申请日:2001-10-05

    IPC分类号: A61K732

    摘要: The invention is a clear, elastomer-free, gel composition comprising: (a) 0.1-25 weight % of an antiperspirant active having a low metal to chloride ratio in the range of 0.9-1.3: 1; (b) 9-23.95 weight % of one or more volatile silicones having a flash point of 100 degrees C or less; (c) 0.05-0.5 weight % of a silicone surfactant having an HLB value≦8; (d) 30-70 weight % water; (e) 0-50 weight % selected water soluble organic solvents; and (f) 0-10 weight % of an emollient; wherein the composition is a liquid gel having a viscosity in the range of 5-50,000 centipoise and a ratio of oil phase to water phase in the range of 10:90 to 24:76.

    摘要翻译: 本发明是一种透明的,无弹性体的凝胶组合物,其包含:(a)0.1至25重量%的低金属与氯化物之比在0.9-1.3:1范围内的止汗活性剂; (b)9-23.95重量%的闪点为100℃以下的一种或多种挥发性有机硅; (c)0.05-0.5重量%的具有HLB值<= 8的硅氧烷表面活性剂; (d)30-70重量%的水; (e)0-50重量%选择的水溶性有机溶剂; 和(f)0-10重量%的润肤剂; 其中所述组合物是粘度在5-50,000厘泊范围内的液体凝胶,油相与水相的比例在10:90至24:76的范围内。

    High oil clear emulsion with elastomer
    42.
    发明授权
    High oil clear emulsion with elastomer 失效
    高透明乳液与弹性体

    公开(公告)号:US06403069B1

    公开(公告)日:2002-06-11

    申请号:US09693248

    申请日:2000-10-20

    IPC分类号: A61K732

    摘要: A clear antiperspirant and/or deodorant composition is disclosed in the form of an emulsion having a refractive index less than 1.42 and comprising: (a) 25-70% of an external phase comprising: (i) 0.1-10%, on an actives basis, of at least one elastomer which is a dimethicone/vinyldimethicone crosspolymer composition made by reacting a polymethylhydrogensiloxane with an alpha, omega-divinylpolydimethyl siloxane for which the dimethicone/vinyl-dimethicone crosspolymer composition is used at a concentration of 4-10% in cyclomethicone, has a refractive index in the range of 1.392-1.402 at 25 degrees C and a viscosity in the range of 0.013-1×104 Pascal seconds; (ii) 0.1-5% of a silicone copolyol having an HLB value ≦8; (iii) 0.1-68% of a volatile silicone selected in an amount to complete the external phase; (iv) 0-10% of a cosurfactant or emulsifier having an HLB value in the range of 1-15; (v) 0-5% of a non-volatile silicone; and (b) 30-75% of an internal phase which is made with: (i) 7-25% (on an anhydrous actives basis (excluding the waters of hydration) of an antiperspirant active; (ii) 0-10% ethanol; (iii) additional water as required to adjust the refractive index; (iv) 0-5% of an antimicrobial agent; and (v) 0-5% of an ionizable salt; wherein the conductance of a water droplet applied to the surface of a thin film of the antiperspirant and/or deodorant composition is at least 250 micro Siemens/cm/ml as measured by a fixed geometry test at a loading of at least 7% by weight level of antiperspirant active.

    摘要翻译: 透明止汗剂和/或除臭剂组合物以折射率小于1.42的乳液的形式公开,并包含:(a)25-70%的外相,其包含:(i)0.1-10%的活性物质 基于至少一种弹性体,其是通过使聚甲基氢硅氧烷与α,ω-二乙烯基聚二甲基硅氧烷反应制备的聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物组合物,其中在聚甲基硅氧烷中以4-10%的浓度使用聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物组合物 在25℃下的折射率在1.392-1.402的范围内,粘度在0.013-1×104帕斯卡秒的范围内; (ii)具有HLB值<= 8的0.1-5%的硅氧烷共聚多元醇; (iii)以完成外相的量选择0.1-68%的挥发性硅氧烷; (iv)0-10%HLB值在1-15范围内的辅助表面活性剂或乳化剂; (v)0-5%的非挥发性硅酮; 和(b)30-75%的内相,其由以下制备:(i)7-25%(基于无水活性物质(不包括水合水合))止汗活性物质;(ii)0-10%乙醇 ;(iii)调整折射率所需的额外的水;(iv)0-5%的抗微生物剂;和(v)0-5%的可电离盐;其中施加到表面的水滴的电导率 的止汗剂和/或除臭剂组合物的薄膜是至少250微西门子/厘米/毫升,通过固定几何测试在至少7重量%的止汗活性剂的负载下测量。

    Oral care film
    49.
    发明申请
    Oral care film 审中-公开
    口腔护理片

    公开(公告)号:US20050281757A1

    公开(公告)日:2005-12-22

    申请号:US10870848

    申请日:2004-06-17

    摘要: A composition for delivery of an oral care substance to a dental surface upon application of the composition thereto is a flexible film comprising the oral care substance dispersed in a film-forming effective amount of a polymeric matrix having a hydrophilic component, e.g., vinylpyrrolidone (VP), and a hydrophobic component, e.g., vinyl acetate (VA), in a weight ratio selected such that the film is substantially dissolvable in saliva in a period of time effective for delivery of the oral care substance. The polymeric matrix illustratively comprises a poly(VP/VA) copolymer having a VP/VA weight ratio of about 90:10 to about 10:90.

    摘要翻译: 用于将组合物施用于口腔护理物质到牙齿表面的组合物是包含分散在成膜有效量的具有亲水组分的聚合物基质例如乙烯基吡咯烷酮(VP)的柔性膜 )和疏水组分,例如乙酸乙烯酯(VA),其选择的重量比使得该膜在有效递送口腔护理物质的时间段内基本上可溶于唾液中。 聚合物基体示例性地包含VP / VA重量比为约90:10至约10:90的聚(VP / VA)共聚物。

    High efficacy, low irritation aluminum salts and related products
    50.
    发明申请
    High efficacy, low irritation aluminum salts and related products 有权
    高效,低刺激性的铝盐及相关产品

    公开(公告)号:US20050158261A1

    公开(公告)日:2005-07-21

    申请号:US11080913

    申请日:2005-03-15

    摘要: A zirconium-free aluminum salt which: (a) has an aluminum to chloride molar ratio in the range of 0.5-2.5:1; (b) comprises a nitrogen containing buffering material in an amount such that the ratio of nitrogen containing material to aluminum is the range of 0.05-0.26:1, and which nitrogen containing material is selected from the group consisting of a nitrogen containing buffering material of formula where n is a number in the range of 1-20, and each of R1, R2, and R3 is independently selected from the group consisting of hydrogen, methyl and ethyl; and (c) the salt has a pH in the range of 2-4 at a concentration of 15%; wherein the salt is free of any other halide scavenging material and has a value of at least 0.50 for the ratio calculated as: area of Peak 5/total area under Peak 2+Peak 3+Peak 4+Peak 5.

    摘要翻译: 一种无锆铝盐,其:(a)铝与氯的摩尔比在0.5-2.5:1的范围内; (b)包括含氮缓冲材料,其含量使得含氮材料与铝的比例为0.05-0.26:1,并且所述含氮材料选自含氮缓冲材料的氮 其中n是1-20范围内的数字,并且R 1,R 2和R 3 3中的每一个独立地被选择 由氢,甲基和乙基组成的组; 和(c)盐的浓度为15%时的pH在2-4范围内; 其中盐不含任何其它卤化物清除材料,并且对于以下计算的比率,其值为至少0.50:峰5的面积/峰2 +峰3 +峰4 +峰5之间的总面积。