公开(公告)号：US20070235347A1

公开(公告)日：2007-10-11

申请号：US11278333

申请日：2006-03-31

申请人： Ronald C. Chatelier ,  Alastair McIndoe Hodges ,  Maria Teodorczyk ,  Remedios Dato

发明人： Ronald C. Chatelier ,  Alastair McIndoe Hodges ,  Maria Teodorczyk ,  Remedios Dato

IPC分类号： G01F1/64 ,  G01N33/487 ,  G01N27/30

CPC分类号： G01N27/3271 ,  C12Q1/001 ,  C12Q1/006 ,  G01N27/3274

摘要： Described herein are systems and methods for distinguishing between a control solution and a blood sample. In one aspect, the methods include using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or a control solution based on at least two characteristics. Further described herein are methods for calculating a discrimination criteria based upon at least two characteristics. Still further described herein are system for distinguishing between blood samples and control solutions.

摘要翻译： 本文描述了用于区分对照溶液和血液样品的系统和方法。 在一个方面，所述方法包括使用测试条，其中通过电连接到电化学测试条的仪表测量多个电流瞬变。 使用电流瞬变来确定样品是否是基于至少两个特征的血液样品或对照溶液。 这里进一步描述的是基于至少两个特征来计算鉴别标准的方法。 本文进一步描述的是用于区分血液样本和对照溶液的系统。

公开(公告)号：US08709739B2

公开(公告)日：2014-04-29

申请号：US13619241

申请日：2012-09-14

申请人： Ronald C. Chatelier ,  Alastair McIndoe Hodges ,  Santhanagopalan Nandagopalan

发明人： Ronald C. Chatelier ,  Alastair McIndoe Hodges ,  Santhanagopalan Nandagopalan

IPC分类号： G01N27/327

CPC分类号： G01N27/4163 ,  C12Q1/006 ,  G01N27/3274

摘要： Methods of determining a corrected analyte concentration in view of some error source are provided herein. The methods can be utilized for the determination of various analytes and/or various sources of error. In one example, the method can be configured to determine a corrected glucose concentration in view of an extreme level of hematocrit found within the sample. In other embodiments, methods are provided for identifying various system errors and/or defects. For example, such errors can include partial-fill or double-fill situations, high track resistance, and/or sample leakage. Systems are also provided for determining a corrected analyte concentration and/or detecting some system error.

公开(公告)号：US08163162B2

公开(公告)日：2012-04-24

申请号：US11278341

申请日：2006-03-31

申请人： Ronald C. Chatelier ,  Alastair McIndoe Hodges ,  Bruce Verity

发明人： Ronald C. Chatelier ,  Alastair McIndoe Hodges ,  Bruce Verity

IPC分类号： G01N27/327

CPC分类号： A61B5/1486 ,  C12Q1/006 ,  G01N27/3274

摘要： Disclosed herein are methods and apparatus for determining analyte concentration in a rapid and accurate manner. The methods include depositing a physiological sample in an electrochemical cell and finding a first and second current transient. Peak current values are obtained from the first and second peak current values and used to reduce the influence of interferents in a current value. Based on this “corrected” current value, an accurate analyte concentration can be determined.

摘要翻译： 本文公开了以快速和准确的方式测定分析物浓度的方法和装置。 所述方法包括在电化学电池中沉积生理样品并找到第一和第二电流瞬变。 从第一和第二峰值电流值获得峰值电流值，并用于减小干扰物在电流值中的影响。 基于该“校正”电流值，可以确定准确的分析物浓度。

公开(公告)号：US20110073493A1

公开(公告)日：2011-03-31

申请号：US12570268

申请日：2009-09-30

申请人： Ronald C. Chatelier ,  Dennis Rylatt

发明人： Ronald C. Chatelier ,  Dennis Rylatt

IPC分类号： G01N33/50 ,  G01N27/26 ,  C09J171/00

CPC分类号： G01N33/54326 ,  G01N33/5438

摘要： An adhesive composition for use in devices and methods for measuring a presence or a concentration of a particular component, such as an antigen, in a sample, such as blood, are provided. In one exemplary embodiment of an adhesive composition, the composition includes an adhesive, water, a poloxamer, and an anticoagulant. The adhesive can include particular properties, such as being hydrophilic, pressure-sensitive, heat-activated, and/or water soluble. The adhesive is particularly useful because it can help improve the flow of sample a device. For example, when the device is an immunosensor, the adhesive can help prevent the blood from clotting in chambers of the immunosensor. This results in a more efficient and accurate determination of the concentration of the sample. Methods of making the composition and device in which the composition can be used are provided, as are methods of using the same.

摘要翻译： 提供了用于测量样品（例如血液）中特定成分（例如抗原）的存在或浓度的装置和方法中的粘合剂组合物。 在粘合剂组合物的一个示例性实施方案中，组合物包括粘合剂，水，泊洛沙姆和抗凝血剂。 粘合剂可以包括特定的性质，例如亲水的，压敏的，热活化的和/或水溶性的。 粘合剂是特别有用的，因为它可以帮助改善样品的流动。 例如，当该装置是免疫传感器时，粘合剂可以帮助防止血液在免疫传感器的腔室内凝结。 这样可以更有效和准确地测定样品的浓度。 提供可以使用组合物的组合物和装置的方法，以及使用该组合物的方法。