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41.发明授权公开(公告)号：US07329279B2
公开(公告)日：2008-02-12
申请号：US10893143
申请日：2004-07-15
申请人： Ulrich R. Haug , Hans F. Valencia , Robert A. Geshlider , Tom Saul , Amr Salahieh , Dwight P. Morejohn
发明人： Ulrich R. Haug , Hans F. Valencia , Robert A. Geshlider , Tom Saul , Amr Salahieh , Dwight P. Morejohn
IPC分类号： A61F2/24
CPC分类号： A61F2/2415 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2230/0054 , A61F2250/0039
摘要： Methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an anchor to a vicinity of the heart valve, the anchor having a braid, and expanding the braid to a deployed configuration against the patient's tissue. The braid may be fabricated from a single strand of wire and/or may comprise at least one the feature.
摘要翻译： 血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和锚固件血管内输送到心脏瓣膜附近，锚具具有编织物，并且将编织物扩展到针对患者组织的展开构型。 编织物可以由单股线制造和/或可以包括至少一个特征。
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公开(公告)号：US08343213B2
公开(公告)日：2013-01-01
申请号：US10971535
申请日：2004-10-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.
摘要翻译： 本发明涉及用于血管内置换患者心脏瓣膜的方法的装置。 该装置包括在锚固件的近端上具有小叶接合元件的可扩张锚和更换阀。 传单接合元件可用于防止远端迁移并确保设备的正确定位。
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公开(公告)号：US20120053683A1
公开(公告)日：2012-03-01
申请号：US13290369
申请日：2011-11-07
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.
摘要翻译： 本发明涉及用于血管内置换患者心脏瓣膜的方法的装置。 该装置包括在锚固件的近端上具有小叶接合元件的可扩张锚和更换阀。 传单接合元件可用于防止远端迁移并确保设备的正确定位。
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公开(公告)号：US09861476B2
公开(公告)日：2018-01-09
申请号：US13290369
申请日：2011-11-07
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.
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公开(公告)号：US07748389B2
公开(公告)日：2010-07-06
申请号：US10972287
申请日：2004-10-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2250/006
摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.
摘要翻译： 本发明涉及用于血管内置换患者心脏瓣膜的方法的装置。 该装置包括在锚固件的近端上具有小叶接合元件的可扩张锚和更换阀。 传单接合元件可用于防止远端迁移并确保设备的正确定位。
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公开(公告)号：US06743169B1
公开(公告)日：2004-06-01
申请号：US09975392
申请日：2001-10-10
申请人： Charles S. Taylor , William N. Aldrich , Thomas L. Baughman , Federico J. Benetti , Brian J. Bennett , Michael J. Billig , Thomas J. Fogarty , John J. Frantzen , Richard S. Ginn , Robert C. Glines , Harry L. Green , Dwight P. Morejohn , Brent Regan , Eugene E. Reis , Amr Salahieh , Ivan Sepetka , Benjamin Sherman , Christian Skieller , Valavanur A. Subramanian , Gary B. Weller , William F. Witt
发明人： Charles S. Taylor , William N. Aldrich , Thomas L. Baughman , Federico J. Benetti , Brian J. Bennett , Michael J. Billig , Thomas J. Fogarty , John J. Frantzen , Richard S. Ginn , Robert C. Glines , Harry L. Green , Dwight P. Morejohn , Brent Regan , Eugene E. Reis , Amr Salahieh , Ivan Sepetka , Benjamin Sherman , Christian Skieller , Valavanur A. Subramanian , Gary B. Weller , William F. Witt
IPC分类号： A61B132
CPC分类号： A61B17/3421 , A61B17/00234 , A61B17/02 , A61B17/0206 , A61B17/0218 , A61B17/0642 , A61B17/12 , A61B17/3423 , A61B17/8076 , A61B90/00 , A61B2017/00243 , A61B2017/00539 , A61B2017/00703 , A61B2017/00858 , A61B2017/00991 , A61B2017/0243 , A61B2017/0648 , A61B2017/1139 , A61B2017/2825 , A61B2017/2913 , A61B2017/2929 , A61B2017/306 , A61B2017/349
摘要： The invention is methods and devices which a surgeon may use to stabilize the beating heart during a surgical procedure on the heart. Pursuant to the invention, a stabilizing device is introduced through an opening in the chest and brought into contact with the beating heart. By contacting the heart with the device and by exerting a stabilizing force on the device, the motion of the heart caused by the contraction of the heart muscles is effectively eliminated such that the heart is stabilized and the site of the surgery moves only minimally if at all. Typically, in separate steps, the surgeon contacts the heart with the stabilizing means, assesses the degree of movement of the anastomosis site, and exerts a force on the stabilizing means such that the contraction of the beating heart causes orgy minimal excess motion at the surgery site. By fixing the position of the stabilizing means in a configuration where the motion of the beating heart is effectively eliminated, the surgeon is able to stabilize the beating heart for the duration of the procedure. The stabilizing means may be attached to a rigid support or may be attached to a semi-rigid support which is rendered motionless mechanically, chemically, or by human intervention. In certain preferred embodiments, the stabilizing means is affixed to a semi-rigid support which is caused to become rigid, by any of a variety of techniques, such that the position of the stabilizing means becomes fixed by the support, and the heart remains substantially motionless for the duration of the procedure.
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公开(公告)号：US20140058324A1
公开(公告)日：2014-02-27
申请号：US14070232
申请日：2013-11-01
申请人： Amr Salahieh , Jonah Lepak , Emma Leung , Tom Saul , Jean-Pierre Dueri , Brice Arnault De La Menardiere , Clayton Baldwin
发明人： Amr Salahieh , Jonah Lepak , Emma Leung , Tom Saul , Jean-Pierre Dueri , Brice Arnault De La Menardiere , Clayton Baldwin
IPC分类号： A61M25/01
CPC分类号： A61M25/0144 , A61B1/00135 , A61B17/00234 , A61B90/10 , A61B2017/00309 , A61B2017/00314 , A61M25/0013 , A61M25/0045 , A61M25/0053 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61M2025/0161
摘要： Steerable medical delivery devices and their methods of use.
摘要翻译： 可导向的医疗输送装置及其使用方法。
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公开(公告)号：US20050143809A1
公开(公告)日：2005-06-30
申请号：US10982388
申请日：2004-11-05
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans Valencia , Daniel Hildebrant , Brian Brandt , Dwight Morejohn , Claudio Argento , Tom Saul , Ulrich Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans Valencia , Daniel Hildebrant , Brian Brandt , Dwight Morejohn , Claudio Argento , Tom Saul , Ulrich Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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公开(公告)号：US20050137701A1
公开(公告)日：2005-06-23
申请号：US10746872
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US20050137686A1
公开(公告)日：2005-06-23
申请号：US10746120
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/2439 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulic or non-pneumatic actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚固件上施加外部非液压或非气动致动力以改变所述锚的形状，诸如通过使用可释放的展开工具向锚固件施加近端和/或远端定向的力以使所述锚或 锚的部分。
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