Analogs of alpha galactosyceramide and uses thereof
    41.
    发明授权
    Analogs of alpha galactosyceramide and uses thereof 有权
    α半乳糖苷酰胺的类似物及其用途

    公开(公告)号:US08039670B2

    公开(公告)日:2011-10-18

    申请号:US12083673

    申请日:2006-10-25

    CPC分类号: C07H15/00

    摘要: There are disclosed compound of formula I, in which R1 represents a hydrophobic moiety adapted to occupy the C′ channel of human CDId, R2 represents a hydrophobic moiety adapted to occupy the A′ channel of human CDId, such that R1 fills at least at least 30% of the occupied volume of the C′ channel compared to the volume occupied by the terminal nC14H29 of the sphingosine chain of α-galactosylceramide when bound to human CDId and R2 fills at least 30% of the occupied volume of the A′ channel compared to the volume occupied by the terminal nC25H51 of the acyl chain of α-galactosylceramide when bound to human CDId R3 represents hydrogen or OH, Ra and Rb each represent hydrogen and in addition, when R3 represents hydrogen, Ra and Rb together may form a single bond, X represents or —CHA(CHOH)nY or —P(=0)(0−)0CH2(CH0H)mY, in which Y represents CHB1B2, n represents an integer from 1 to 4, m represents 0 or 1, A årepresents hydrogen, one of B1 and B2 represents H, OH or phenyl, and the other represents hydrogen or one of B1 and B2 represents hydroxyl and the other represents phenyl, in addition, when n represents 4, then A together with one of B1 and B2 together forms a single bond and the other of B1 and B2 represents H, OH or OSO3H and pharmaceutically acceptable salts thereof; the compounds of formula I are indicted for use in the treatment of a virus, microbial infection, parasite, an autoimmune disease, cancer, allergy or asthma.

    摘要翻译: 公开了式I的化合物,其中R 1表示适于占据人CD1d的C'通道的疏水性部分,R 2表示适于占据人CDId的A'通道的疏水部分,使得R1至少填充至少 比较C'通道的占据体积的30%,与结合人CD1d和R2的α-半乳糖神经酰胺的鞘氨醇链末端nC14H29占据的体积相比,填充了A'通道占据体积的至少30% 与α-galactosylceramide的酰基链末端nC25H51所占的体积结合到人CDID R3表示氢或OH,Ra和Rb各自表示氢,另外,当R 3表示氢时,R a和R b可以一起形成单 键,X表示或-CHA(CHOH)nY或-P(= O)(0-)0CH 2(CHOH)mY,其中Y表示CHB1B2,n表示1至4的整数,m表示0或1,A 表示氢,B1和B2之一表示H,OH或苯基 另一个代表氢或B1和B2之一表示羟基,另一个表示苯基,另外,当n表示4时,则A与B1和B2中的一个一起形成单键,而B1和B2中的另一个 表示H,OH或OSO 3 H及其药学上可接受的盐; 式I的化合物被指示用于治疗病毒,微生物感染,寄生虫,自身免疫疾病,癌症,变态反应或哮喘。

    Machine tool or production machine or robot
    42.
    发明授权
    Machine tool or production machine or robot 有权
    机床或生产机器或机器人

    公开(公告)号:US07997905B2

    公开(公告)日:2011-08-16

    申请号:US12308425

    申请日:2007-04-13

    IPC分类号: H01R39/30

    CPC分类号: H01R39/646

    摘要: A machine tool or a production machine, such as e.g. a multispindle machine, or a robot, is described, wherein a liquid metal lubricated slide bearing is not only used to transmit feed currents for electrical consumers but also to transmit currents for producing control signals. Accordingly, it is possible to apply via the liquid metal lubricated slide bearings a voltage of 600 volts in order to produce feed currents and a voltage of 24 volts in order to produce control signals.

    摘要翻译: 机床或生产机器,例如, 描述了一种多轴机器或机器人,其中液态金属润滑的滑动轴承不仅用于传送用户的馈送电流,而且用于传输用于产生控制信号的电流。 因此,为了产生控制信号,可以经由液态金属润滑的滑动轴承施加600伏特的电压,以产生24伏特的馈电电流和电压。

    CONVERTER MOTOR
    43.
    发明申请
    CONVERTER MOTOR 审中-公开
    转换电机

    公开(公告)号:US20110043082A1

    公开(公告)日:2011-02-24

    申请号:US12866388

    申请日:2008-10-13

    IPC分类号: H02K11/00

    CPC分类号: H05K7/20909 H02K11/33

    摘要: The invention relates to an inverter motor comprising a motor (2) and an inverter (4), wherein components of inverter electronics are disposed on a circuit board such that the lossy components are thermally conductively connected to a heat sink (8) designed as a cover of an inverter housing made of thermally insulating plastic, wherein said inverter housing made of thermally insulating plastic is axially mounted on a B-side of the motor (2). According to the invention, the circuit board (14) is divided into a plurality of circuit board elements edged relative to each other such that circuit board segments having components having lower power loss are each thermally conductively connected to a wall of an inverter housing wall (6), and that a central circuit board segment having lossy components is thermally conductively connected to a heat sink made of thermally conductive plastic, and the motor (2) has a bulkhead (16) made of thermally insulating material on the B side thereof, whereon a connector strip (18) is disposed. The result is a compact, fanless inverter motor.

    摘要翻译: 本发明涉及一种包括电动机(2)和逆变器(4)的逆变器电动机,其中逆变器电子部件的部件设置在电路板上,使得有损部件被热传导地连接到设计为 由隔热塑料制成的逆变器壳体的盖子,其中由绝热塑料制成的所述逆变器壳体轴向安装在电动机(2)的B侧上。 根据本发明,电路板(14)被分成多个相对于彼此边缘的电路板元件,使得具有较低功率损耗的元件的电路板段各自热传导连接到逆变器外壳壁的壁( 6),并且具有有损组件的中心电路板段导热地连接到由导热塑料制成的散热器,并且电动机(2)在其B侧具有由隔热材料制成的隔板(16) 在其中布置有连接器条(18)。 结果是紧凑型无风扇的逆变电机。

    Machine Tool or Production Machine or Robot
    44.
    发明申请
    Machine Tool or Production Machine or Robot 有权
    机床或生产机器或机器人

    公开(公告)号:US20100317201A1

    公开(公告)日:2010-12-16

    申请号:US12308425

    申请日:2007-04-13

    IPC分类号: H01R39/30

    CPC分类号: H01R39/646

    摘要: A machine tool or a production machine, such as e.g. a multispindle machine, or a robot, is described, wherein a liquid metal lubricated slide bearing is not only used to transmit feed currents for electrical consumers but also to transmit currents for producing control signals. Accordingly, it is possible to apply via the liquid metal lubricated slide bearings a voltage of 600 volts in order to produce feed currents and a voltage of 24 volts in order to produce control signals.

    摘要翻译: 机床或生产机器,例如, 描述了一种多轴机器或机器人,其中液态金属润滑的滑动轴承不仅用于传送用户的馈送电流,而且用于传输用于产生控制信号的电流。 因此,为了产生控制信号,可以经由液态金属润滑的滑动轴承施加600伏特的电压,以产生24伏特的馈电电流和电压。

    FUEL CELL SYSTEM AND CORRESPONDING OPERATING PROCESS
    45.
    发明申请
    FUEL CELL SYSTEM AND CORRESPONDING OPERATING PROCESS 有权
    燃料电池系统及相应的操作过程

    公开(公告)号:US20100209790A1

    公开(公告)日:2010-08-19

    申请号:US12707093

    申请日:2010-02-17

    IPC分类号: H01M8/18

    摘要: A process is provided for operating a fuel cell system (1), especially in a motor vehicle, wherein the fuel cell system (1) includes at least one reformer (2) and at least one fuel cell (3). To prolong the service life of the system (1), a warm-holding mode is carried out after switching off the fuel cell system (1). During the warm-holding mode an educt containing hydrogen and carbon monoxide is fed to the reformer (2) and reacted with air in reformer (2) at a catalyst (5) of reformer (2) in an exothermal reaction.

    摘要翻译: 提供了用于操作燃料电池系统(1)的方法,特别是在机动车辆中,其中燃料电池系统(1)包括至少一个重整器(2)和至少一个燃料电池(3)。 为了延长系统(1)的使用寿命,在关闭燃料电池系统(1)之后进行保暖模式。 在保温模式期间,将含有氢和一氧化碳的流出物供给到重整器(2)中,并在重整器(2)的催化剂(5)中与放热反应中的空气反应。

    FUEL CELL SYSTEM AND PROCESS FOR OPERATING SAME
    46.
    发明申请
    FUEL CELL SYSTEM AND PROCESS FOR OPERATING SAME 有权
    燃料电池系统及其操作方法

    公开(公告)号:US20100209789A1

    公开(公告)日:2010-08-19

    申请号:US12707064

    申请日:2010-02-17

    IPC分类号: H01M8/18

    摘要: A process for operating a fuel cell system (1), especially in a motor vehicle. The fuel cell system (1) includes at least one fuel cell (3) as well as at least one reformer (2). To improve the possibility of warm start, a warm-holding mode, in which heat transfer takes place from the fuel cell (3) to the reformer (2), is activated after switching off the fuel cell system (1).

    摘要翻译: 一种用于操作燃料电池系统(1)的方法,特别是在机动车辆中。 燃料电池系统(1)包括至少一个燃料电池(3)以及至少一个重整器(2)。 为了提高热启动的可能性,在关闭燃料电池系统(1)之后,启动从燃料电池(3)向重整器(2)进行热传递的温暖保持模式。

    DEVICE AND METHOD FOR PRODUCING A SEAL
    47.
    发明申请
    DEVICE AND METHOD FOR PRODUCING A SEAL 审中-公开
    用于生产密封的装置和方法

    公开(公告)号:US20100052260A1

    公开(公告)日:2010-03-04

    申请号:US12449971

    申请日:2007-03-07

    IPC分类号: F16J15/02

    摘要: A device is disclosed for producing a seal between a first part and a second part, especially a first housing part and a second housing part. The seal can be produced according to a physical property of an electroactive plastic material which can be modified. A device for receiving an electrical circuit and/or a device including electrical switching device is also disclosed, having at least one first and one second housing part operating as a first part and a second part, with an above-mentioned device. A method is further disclosed for producing a seal between a first part and a second part, especially a first housing part and a second housing part, by way of such a device, a first electrical voltage being applied to create the seal, and a second electrical voltage being applied to lift the seal.

    摘要翻译: 公开了用于在第一部分和第二部分之间产生密封的装置,特别是第一壳体部分和第二壳体部分。 密封件可以根据可以修改的电活性塑料材料的物理性质来生产。 还公开了一种用于接收电路和/或包括电气开关装置的装置的装置,其具有至少一个第一和第二壳体部分作为第一部分操作,而第二部分具有上述装置。 还公开了一种用于通过这种装置在第一部分和第二部分,特别是第一壳体部分和第二壳体部分之间产生密封的方法,施加第一电压以产生密封,以及第二部分 施加电压以提升密封。

    Machine with data transfer from one machine part to another machine part which is able to be rotated relative to the one machine part
    48.
    发明授权
    Machine with data transfer from one machine part to another machine part which is able to be rotated relative to the one machine part 有权
    具有从一个机器部件到另一个机器部件的数据传输的机器,其能够相对于一个机器部件旋转

    公开(公告)号:US07668418B2

    公开(公告)日:2010-02-23

    申请号:US12316691

    申请日:2008-12-16

    IPC分类号: G02B6/26 G02B6/42

    CPC分类号: H04B10/801

    摘要: A machine having two machine parts, of which one is able to be rotated relative to the other, in which light signals are transferred from the one part to the other part. The light signals are transmitted radially to the axis of rotation of the rotatable machine part. In a first embodiment a plurality of light sources couple light into an optical waveguide ring which is coupled out over the entire outer circle of the optical waveguide ring so that it is guaranteed that light signals reach a receiver arranged radially outside in each case. In another embodiment light sources couple light into optical waveguide structures, with branches of the optical waveguides guaranteeing that on the outer circle of the one component the exit points for light are sufficiently dense that for any given angular position of the rotatable component at least one of two receivers receives a light signal.

    摘要翻译: 具有两个机器部件的机器,其中一个机器部件能够相对于另一个部件旋转,其中光信号从该部件转移到另一部件。 光信号径向地传递到可旋转机器部件的旋转轴线。 在第一实施例中,多个光源将光耦合到光波导环中,该光波导环耦合在光波导环的整个外圆上,使得保证光信号到达在每种情况下径向外侧布置的接收器。 在另一个实施例中,光源将光耦合到光波导结构中,其中光波导的分支保证在一个部件的外圆上,用于光的出射点足够致密,对于可旋转部件的任何给定的角位置,至少一个 两个接收器接收光信号。

    Analogs of Alpha Galactosyceramide and Uses thereof
    49.
    发明申请
    Analogs of Alpha Galactosyceramide and Uses thereof 有权
    α半乳糖苷酰胺的类似物及其用途

    公开(公告)号:US20090239813A1

    公开(公告)日:2009-09-24

    申请号:US12083673

    申请日:2006-10-25

    CPC分类号: C07H15/00

    摘要: There are disclosed compound of formula I, in which R1 represents a hydrophobic moiety adapted to occupy the C′ channel of human CDId, R2 represents a hydrophobic moiety adapted to occupy the A′ channel of human CDId, such that R1 fills at least at least 30% of the occupied volume of the C′ channel compared to the volume occupied by the terminal nC14H29 of the sphingosine chain of α-galactosylceramide when bound to human CDId and R2 fills at least 30% of the occupied volume of the A′ channel compared to the volume occupied by the terminal nC25H51 of the acyl chain of α-galactosylceramide when bound to human CDId R3 represents hydrogen or OH, Ra and Rb each represent hydrogen and in addition, when R3 represents hydrogen, Ra and Rb together may form a single bond, X represents or —CHA(CHOH)nY or —P(═0)(0−)0CH2(CH0H)mY, in which Y represents CHB1B2, n represents an integer from 1 to 4, m represents 0 or 1, A årepresents hydrogen, one of B1 and B2 represents H, OH or phenyl, and the other represents hydrogen or one of B1 and B2 represents hydroxyl and the other represents phenyl, in addition, when n represents 4, then A together with one of B1 and B2 together forms a single bond and the other of B1 and B2 represents H, OH or OSO3H and pharmaceutically acceptable salts thereof; the compounds of formula I are indicted for use in the treatment of a virus, microbial infection, parasite, an autoimmune disease, cancer, allergy or asthma

    摘要翻译: 公开了式I的化合物,其中R 1表示适于占据人CD1d的C'通道的疏水性部分,R 2表示适于占据人CDId的A'通道的疏水部分,使得R1至少填充至少 比较C'通道的占据体积的30%,与结合人CDd1和R2的α-半乳糖神经酰胺的鞘氨醇链末端nC14H29占据的体积相比填充了A'通道占据体积的至少30% 与α-半乳糖神经酰胺的末端nC25H51所占的体积结合于人CD1a3表示氢或OH,Ra和Rb各自表示氢,另外,当R 3表示氢时,R a和R b可以一起形成单 键,X表示或-CHA(CHOH)nY或-P(-O)(0-)0CH 2(CHOH)mY,其中Y表示CHB1B2,n表示1至4的整数,m表示0或1,A 表示氢,B1和B2之一表示H,OH或苯基,t表示氢 另外表示氢或B1之一,B2表示羟基,另一个表示苯基,另外,当n表示4时,则A与B1和B2中的一个一起形成单键,B1和B2中的另一个表示H, OH或OSO3H及其药学上可接受的盐; 式I的化合物被指示用于治疗病毒,微生物感染,寄生虫,自身免疫性疾病,癌症,变态反应或哮喘