公开(公告)号：US20220104737A1

公开(公告)日：2022-04-07

申请号：US17061344

申请日：2020-10-01

Applicant: Covidien LP

Inventor： Philip C. Smit ,  Andre Antunes ,  Dean Montgomery ,  Paul S. Addison

IPC: A61B5/1455 ,  A61B5/00

Abstract: In some examples, a system includes an oxygen saturation sensing device configured to sense an oxygen saturation level of a patient and processing circuitry. The processing circuitry may be configured to receive a signal indicative of the oxygen saturation level of the patient, determine that the signal indicates the oxygen saturation level is at or below a desaturation threshold, and in response to determining the oxygen saturation level of the patient is at or below the desaturation threshold, predict, using an oxygen saturation prediction model, whether the oxygen saturation level of the patient will increase above the desaturation threshold by the end of a predefined time period. In response to predicting that the oxygen saturation level of the patient will increase above the desaturation threshold by the end of the predefined time period, the processing circuitry refrains from outputting an indication of the patient experiencing an oxygen desaturation event.

公开(公告)号：US20220015696A1

公开(公告)日：2022-01-20

申请号：US16933745

申请日：2020-07-20

Applicant: Covidien LP

Inventor： Paul S. Addison ,  Dean Montgomery

IPC: A61B5/00 ,  A61B34/10 ,  A61B34/00 ,  A61B34/30 ,  G16H20/10 ,  G16H40/60

Abstract: A patient monitoring system may include processing circuitry configured to receive an indication of a surgical event, obtain a nociception parameter of a patient, compare the nociception parameter of the patient to a nociception threshold to detect a nociception event, determine whether the surgical event corresponds to the nociception event, and in response to determinizing whether the surgical event corresponds to the nociception event, provide an indication to adjust an amount of analgesic administered to the patient.

公开(公告)号：US11026586B2

公开(公告)日：2021-06-08

申请号：US15962438

申请日：2018-04-25

Applicant: Covidien LP

Inventor： Paul S. Addison ,  Dean Montgomery ,  James N. Watson

IPC: A61B5/0205 ,  A61B5/021 ,  A61B5/0295 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/024

Abstract: In some examples, a device includes processing circuitry configured to receive first and second signals indicative of first and second physiological parameters, respectively, of a patient. The processing circuitry is also configured to determine a first estimate of a limit of autoregulation of the patient based on the first and second signals. The processing circuitry is further configured to determine a difference between the first estimate of the limit of autoregulation and one or more other estimates of the limit of autoregulation. The processing circuitry is configured to determine a weighted average of the first estimate and a previous value of the limit of autoregulation based on the difference between the first estimate and the one or more other estimates. The processing circuitry is configured to determine an autoregulation status based on the weighted average and output, for display via the display, an indication of the autoregulation status.

公开(公告)号：US10932724B2

公开(公告)日：2021-03-02

申请号：US15184305

申请日：2016-06-16

Applicant: COVIDIEN LP

Inventor： Paul S. Addison ,  Dean Montgomery ,  James N. Watson

IPC: A61B5/02 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/1455 ,  A61B5/145 ,  A61B5/021

Abstract: A method for monitoring autoregulation includes, using a processor, receiving a blood pressure signal, a regional oxygen saturation signal, and a blood volume signal from a patient. The method also includes determining a first linear correlation between the blood pressure signal and the regional oxygen saturation signal and determining a second linear correlation between the blood pressure signal and the blood volume signal. The method also includes determining a confidence level associated with the first linear correlation based at least in part on the second linear correlation and providing a signal indicative of the patient's autoregulation status to an output device based on the linear correlation and the confidence level.

公开(公告)号：US10932673B2

公开(公告)日：2021-03-02

申请号：US16165108

申请日：2018-10-19

Applicant: Covidien LP

Inventor： Paul S. Addison ,  Dean Montgomery ,  Andre Antunes

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/20 ,  G16H10/60 ,  A61B5/1455 ,  A61B5/021

Abstract: A system for monitoring autoregulation may include processing circuitry configured to receive a blood pressure signal indicative of an acquisition blood pressure of a patient at an acquisition site and an oxygen saturation signal indicative of an oxygen saturation of the patient. The processing circuitry may determine a cerebral autoregulation status value based on the blood pressure signal and the oxygen saturation signal. The processing circuitry may determine a non-cerebral autoregulation status value based on the cerebral autoregulation status value and an adjustment value. The processing circuitry provide to an output device a signal indicative of the non-cerebral autoregulation status value and a signal indicative of the cerebral autoregulation status value to enable a clinician to monitor the autoregulation status of the patient.

公开(公告)号：US20160324425A1

公开(公告)日：2016-11-10

申请号：US15146595

申请日：2016-05-04

Applicant: COVIDIEN LP

Inventor： Paul S. Addison ,  Dean Montgomery

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/0205 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/14551 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/6801 ,  A61B5/7264 ,  A61B5/7275 ,  G06F19/00 ,  G16H50/20

Abstract: A method for monitoring autoregulation includes using a processor for receiving one or more physiological signals, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, calculating a data clustering metric indicative of a distribution of the correlation-based measure within a window of blood pressures, and determining whether the window of blood pressures is within an intact autoregulation zone or an impaired autoregulation zone based at least in part on the data clustering metric.

Abstract translation: 一种用于监测自动调节的方法包括使用处理器来接收一个或多个生理信号，基于所述一个或多个生理信号确定指示患者的自动调节的基于相关的测量，计算指示所述相关性调节的分布的数据聚类度量， 以及至少部分地基于所述数据聚类度量来确定所述血压窗口是否处于完整的自动调节区域或受损的自动调节区域内。

公开(公告)号：US12268479B2

公开(公告)日：2025-04-08

申请号：US18320400

申请日：2023-05-19

Applicant: Covidien LP

Inventor： Paul Stanley Addison ,  James N. Watson ,  Dean Montgomery

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/02 ,  A61B5/021 ,  A61B5/026 ,  A61B5/145 ,  A61B5/1455 ,  G16H40/63 ,  G16H50/20 ,  G16H50/30 ,  A61B5/03

Abstract: A method for monitoring autoregulation includes, using a processor, using a processor to execute one or more routines on a memory. The one or more routines include receiving one or more physiological signals from a patient, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, and generating an autoregulation profile of the patient based on autoregulation index values of the correlation-based measure. The autoregulation profile includes the autoregulation index values sorted into bins corresponding to different blood pressure ranges. The one or more routines also include designating a blood pressure range encompassing one or more of the bins as a blood pressure safe zone indicative of intact regulation and providing a signal to a display to display the autoregulation profile and a first indicator of the blood pressure safe zone.

公开(公告)号：US20250009312A1

公开(公告)日：2025-01-09

申请号：US18890641

申请日：2024-09-19

Applicant: COVIDIEN LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Peter Galen

IPC: A61B5/00 ,  A61B5/021 ,  A61B5/1455 ,  G16H50/30

Abstract: A system for monitoring autoregulation includes an oxygen saturation sensor configured to obtain an oxygen saturation signal indicative of an oxygen saturation of a patient. The system also includes a controller having a processor configured to receive a blood pressure signal indicative of a blood pressure of the patient and the oxygen saturation signal, determine a change in the oxygen saturation signal and a change in the blood pressure signal over a period of time, and provide an indication that the patient's autoregulation is intact if the oxygen saturation changes by more than an oxygen saturation threshold and if the blood pressure changes by less than a blood pressure threshold during the period of time.

公开(公告)号：US12121370B2

公开(公告)日：2024-10-22

申请号：US16921416

申请日：2020-07-06

Applicant: Covidien LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Peter Galen

IPC: A61B5/00 ,  A61B5/021 ,  A61B5/1455 ,  G16H50/30

CPC classification number: A61B5/7275 ,  A61B5/021 ,  A61B5/14551 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/7246 ,  G16H50/30

Abstract: A system for monitoring autoregulation includes an oxygen saturation sensor configured to obtain an oxygen saturation signal indicative of an oxygen saturation of a patient. The system also includes a controller having a processor configured to receive a blood pressure signal indicative of a blood pressure of the patient and the oxygen saturation signal, determine a change in the oxygen saturation signal and a change in the blood pressure signal over a period of time, and provide an indication that the patient's autoregulation is intact if the oxygen saturation changes by more than an oxygen saturation threshold and if the blood pressure changes by less than a blood pressure threshold during the period of time.

公开(公告)号：US11839471B2

公开(公告)日：2023-12-12

申请号：US17210222

申请日：2021-03-23

Applicant: Covidien LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Andre Antunes

IPC: A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14553 ,  A61B5/7264

Abstract: In some examples, a system is configured to determine, using a neural network algorithm of a cerebral autoregulation model, a cerebral autoregulation status of the patient based at least in part on a blood pressure of the patient over a period of time and regional cerebral oxygen saturation of the patient over the period of time.