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    DETERMINATION OF DIPOLE FOR TISSUE CONDUCTANCE COMMUNICATION
    41.
    发明申请
    DETERMINATION OF DIPOLE FOR TISSUE CONDUCTANCE COMMUNICATION 有权
    用于组织结构通信的DIPOLE的确定

    公开(公告)号：US20120109258A1

    公开(公告)日：2012-05-03

    申请号：US12915788

    申请日：2010-10-29

    申请人： Can Cinbis ,  David A. Anderson ,  Michael A. Reinert ,  Xiaonan Shen ,  James K. Carney ,  Michael B. Terry

    发明人： Can Cinbis ,  David A. Anderson ,  Michael A. Reinert ,  Xiaonan Shen ,  James K. Carney ,  Michael B. Terry

    IPC分类号： A61N1/08

    CPC分类号： A61N1/37217 ,  A61B5/0028 ,  A61N1/08 ,  H04B13/005

    摘要： Aspects of the present disclosure include a medical device system including an implantable medical device and an external device with three or more electrodes configured to contact a patient's skin. The external device either transmits or receives a test signal to or from the implantable medical device using a plurality of possible receive dipoles, where each possible receive dipole is formed by a pair of electrodes. A signal quality monitor, either at the implantable medical device or at the external device, measures a signal quality for the possible receive dipoles.

    摘要翻译： 本公开的方面包括包括可植入医疗装置的医疗装置系统和具有被配置为接触患者皮肤的三个或更多个电极的外部装置。 外部设备使用多个可能的接收偶极子向可植入医疗设备发送测试信号或从可植入医疗设备接收测试信号，其中每个可能的接收偶极由一对电极形成。 在可植入医疗设备或外部设备处的信号质量监视器测量可能的接收偶极子的信号质量。

    Implantable tissue perfusion sensing system and method
    42.
    发明授权
    Implantable tissue perfusion sensing system and method 有权
    植入式组织灌注感应系统及方法

    公开(公告)号：US08038626B2

    公开(公告)日：2011-10-18

    申请号：US12039326

    申请日：2008-02-28

    申请人： Can Cinbis ,  James K. Carney

    发明人： Can Cinbis ,  James K. Carney

    IPC分类号： A61B5/02

    CPC分类号： A61B5/1459 ,  A61B5/0059 ,  A61B5/024 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/14542 ,  A61B5/7214 ,  A61N1/3925

    摘要： A medical device system for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, determines changes in perfusion in response to first changes in the plurality of light measurements in a direction indicative of a decrease in blood oxygenation and second changes in a direction indicative of a decrease in blood volume, and adjusts delivery of therapy by the device in response to the determined loss of perfusion.

    摘要翻译： 一种用于感测心脏事件的医疗装置系统，其包括感测用于识别心脏事件的心脏信号的多个电极，能够发射多个波长的光的多个光源和检测发射光的检测器。 处理器响应于由检测器检测到的发射光来确定多个光测量值，响应于多个光测量中指示血氧饱和度降低的方向和方向上的第二变化的方向响应于第一变化来确定灌注变化 指示血容量的减少，并且响应于确定的灌注损失来调整装置的治疗递送。

    OPTICAL SENSOR FOR MEDICAL DEVICE
    44.
    发明申请
    OPTICAL SENSOR FOR MEDICAL DEVICE 有权
    光学传感器医疗器械

    公开(公告)号：US20110190609A1

    公开(公告)日：2011-08-04

    申请号：US12765396

    申请日：2010-04-22

    申请人： Jonathan L. Kuhn ,  Thomas A. Anderson ,  Can Cinbis ,  Jeffrey M. Jelen ,  Timothy Davis ,  James K. Carney

    发明人： Jonathan L. Kuhn ,  Thomas A. Anderson ,  Can Cinbis ,  Jeffrey M. Jelen ,  Timothy Davis ,  James K. Carney

    IPC分类号： A61B5/1455 ,  H01L31/0232 ,  A61N1/04

    CPC分类号： A61N1/3702 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/6846 ,  A61N1/36557 ,  Y10T29/49002

    摘要： An optical sensor for a medical device includes a fixed lens spacing between emit and receive modules to achieve target sensor sensitivity, while varying other sensor parameters in order to increase signal amplitude without increasing power demand. An optical sensor connected to a housing of a medical device includes a circuit board, an opto-electronic component, a wall, a lens, and a ferrule. The circuit board is arranged within the housing. The opto-electronic component is mounted on a surface of the circuit board. The wall protrudes from the surface of the circuit board and surrounds the opto-electronic component. The lens is offset from the surface of the circuit board. The ferrule is connected to the housing, the lens and the wall. An inner surface of the wall mates with an outer surface of the ferrule.

    摘要翻译： 用于医疗装置的光学传感器包括发射和接收模块之间的固定透镜间隔，以实现目标传感器灵敏度，同时改变其它传感器参数，以便增加信号幅度而不增加功率需求。 连接到医疗装置的壳体的光学传感器包括电路板，光电子部件，壁，透镜和套圈。 电路板布置在外壳内。 光电子部件安装在电路板的表面上。 壁从电路板的表面突出并围绕光电子部件。 透镜偏离电路板的表面。 套圈连接到外壳，透镜和墙壁。 壁的内表面与套圈的外表面配合。

    IMPLANTABLE TISSUE PERFUSION SENSING SYSTEM AND METHOD
    45.
    发明申请
    IMPLANTABLE TISSUE PERFUSION SENSING SYSTEM AND METHOD 有权
    可植入组织渗透感应系统及方法

    公开(公告)号：US20080208067A1

    公开(公告)日：2008-08-28

    申请号：US12039281

    申请日：2008-02-28

    申请人： Can Cinbis ,  James K. Carney

    发明人： Can Cinbis ,  James K. Carney

    IPC分类号： A61B5/02

    CPC分类号： A61B5/1459 ,  A61B5/0059 ,  A61B5/024 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/14542 ,  A61B5/7214 ,  A61N1/3925

    摘要： A medical device for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, and generates a blood volume index in response to a light source of the plurality of light sources emitting light at an isobestic wavelength. The blood volume index is then utilized to verify the identifying of the cardiac event.

    摘要翻译： 一种用于感测心脏事件的医疗装置，其包括感测用于识别心脏事件的心脏信号的多个电极，能够发射多个波长的光的多个光源以及检测发射光的检测器。 处理器响应于由检测器检测到的发射光来确定多个光测量，并且响应于以异常波长发射光的多个光源的光源产生血液体积指数。 然后利用血容量指数来验证心脏事件的识别。

    IMPLANTABLE TISSUE PERFUSION SENSING SYSTEM AND METHOD
    46.
    发明申请
    IMPLANTABLE TISSUE PERFUSION SENSING SYSTEM AND METHOD 有权
    可植入组织渗透感应系统及方法

    公开(公告)号：US20080208020A1

    公开(公告)日：2008-08-28

    申请号：US12039263

    申请日：2008-02-28

    申请人： Can Cinbis ,  James K. Carney

    发明人： Can Cinbis ,  James K. Carney

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/1459 ,  A61B5/0059 ,  A61B5/024 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/14542 ,  A61B5/7214 ,  A61N1/3925

    摘要： A medical device for sensing cardiac events that includes a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, updates, for each of the plurality of wavelengths, a first normalization coefficient and a second normalization coefficient in response to the detected emitted light, and adjusts the determined plurality of light measurements in response to the first normalization coefficient and the second normalization coefficient.

    摘要翻译： 一种用于感测心脏事件的医疗装置，其包括能够发射多个波长的光的多个光源，以及检测器，用于检测发射的光。 处理器响应于由检测器检测到的发射光来确定多个光测量，响应于检测到的发射光，针对多个波长中的每一个更新第一归一化系数和第二归一化系数，并且调整所确定的 响应于第一归一化系数和第二归一化系数的多个光测量。

    Testing communication during implantation
    48.
    发明授权
    Testing communication during implantation 有权
    测量植入过程中的沟通

    公开(公告)号：US08983619B2

    公开(公告)日：2015-03-17

    申请号：US12732403

    申请日：2010-03-26

    申请人： Can Cinbis ,  H. Toby Markowitz

    发明人： Can Cinbis ,  H. Toby Markowitz

    IPC分类号： A61N1/08 ,  A61B5/00 ,  A61N1/372 ,  A61B19/00 ,  A61N1/375

    CPC分类号： A61B5/0028 ,  A61B5/0031 ,  A61B2034/2053 ,  A61B2560/0271 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37241 ,  A61N1/3756

    摘要： A system and method are described for testing communication through a patient during implantation using telemetry coupling electrodes on a delivery catheter. In one example, at least two telemetry coupling electrodes may be placed on or within a delivery catheter to test conductive communication with external body electrodes during implantation. In some instances, the telemetry coupling electrodes of the delivery catheter may approximate the spacing of telemetry electrodes on an IMD. In this manner, testing conductively coupled communication with telemetry coupling electrodes of the catheter may be used to mimic the telemetry electrodes on the IMD and determine a target position and/or orientation of an electrode or electrodes of the IMD for successful conductive communication through the body.

    摘要翻译： 描述了一种系统和方法，用于在植入期间通过患者使用传送导管上的遥测耦合电极来测试通信。 在一个示例中，至少两个遥测耦合电极可以放置在输送导管上或内部，以在植入期间测试与外部身体电极的导电连通。 在一些情况下，输送导管的遥测耦合电极可以接近IMD上遥测电极的间距。 以这种方式，测试与导管的遥测耦合电极的导电耦合通信可以用于模拟IMD上的遥测电极，并且确定IMD的电极或电极的目标位置和/或取向以便通过身体成功地导电连通 。

    Wireless cardiac pulsatility sensing
    50.
    发明授权
    Wireless cardiac pulsatility sensing 有权
    无线心脏搏动检测

    公开(公告)号：US08244339B2

    公开(公告)日：2012-08-14

    申请号：US12852740

    申请日：2010-08-09

    申请人： Xiaonan Shen ,  Can Cinbis

    发明人： Xiaonan Shen ,  Can Cinbis

    IPC分类号： A61B5/04

    CPC分类号： A61B5/6846 ,  A61B5/0245 ,  A61B5/0538 ,  A61N1/3937 ,  A61N1/3956 ,  A61N1/3987

    摘要： An implantable medical device system and associated method monitor changes in transimpedance in a body tissue due to changes in cardiac pulsatility. A first dipole is used to deliver a non-stimulating electrical current. The first dipole includes a first electrode and a second electrode adapted to be deployed along a first body location. A second dipole is used to measure a voltage resulting from the non-stimulating electrical current being conducted through a portion of a patient's body. The second dipole includes a third electrode and a fourth electrode different than the first electrode and the second electrode and adapted to be deployed along a second body location spaced apart from the first body location.

    摘要翻译： 可植入医疗装置系统和相关方法监测由于心脏搏动的变化而导致的身体组织中的跨阻抗变化。 第一偶极子用于传递非刺激电流。 第一偶极子包括适于沿着第一身体位置展开的第一电极和第二电极。 使用第二偶极子来测量通过患者身体的一部分传导的非刺激性电流产生的电压。 第二偶极子包括不同于第一电极和第二电极的第三电极和第四电极，并且适于沿着与第一主体位置间隔开的第二主体位置展开。