Tissue oxygenation monitoring in heart failure
    3.
    发明授权
    Tissue oxygenation monitoring in heart failure 有权
    心力衰竭组织氧合监测

    公开(公告)号:US08571620B2

    公开(公告)日:2013-10-29

    申请号:US12797816

    申请日:2010-06-10

    IPC分类号: A61B5/00

    CPC分类号: A61N1/36557

    摘要: A medical device system and associated method are used for monitoring a heart failure patient. A medical device for monitoring delivery of a therapy includes a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient, a therapy delivery module to deliver a therapy, and a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement.

    摘要翻译: 医疗器械系统和相关方法用于监测心力衰竭患者。 用于监测治疗递送的医疗装置包括传感器,其感测对应于患者的身体组织的体积的光衰减的光学传感器信号,用于递送治疗的治疗递送模块和被配置为计算第一组织氧合的处理器 在开始递送治疗之前从光学传感器信号进行的测量,在开始递送治疗之后从光学传感器信号计算第二组织氧合测量,比较第一和第二组织氧合测量,并确定递送的治疗是否为 成功地响应于第一次组织氧合测量和第二次组织氧合测量。

    Tissue Oxygenation Monitoring in Heart Failure
    4.
    发明申请
    Tissue Oxygenation Monitoring in Heart Failure 审中-公开
    心力衰竭组织氧合监测

    公开(公告)号:US20100318146A1

    公开(公告)日:2010-12-16

    申请号:US12797815

    申请日:2010-06-10

    IPC分类号: A61N1/365

    CPC分类号: A61N1/36557

    摘要: A medical device for monitoring delivery of a therapy that includes a therapy delivery module to deliver a therapy, a controller to set a therapy delivery control parameter, an optical sensor to produce a signal corresponding to tissue light attenuation, and a processor configured to compute a tissue oxygenation measurement from the optical sensor signal, wherein the controller, the optical sensor, and the processor operate cooperatively to determine a setting of the therapy delivery control parameter corresponding to a maximum tissue oxygenation.

    摘要翻译: 一种用于监测治疗递送的医疗装置,其包括用于递送疗法的治疗递送模块,用于设置治疗递送控制参数的控制器,用于产生对应于组织光衰减的信号的光学传感器,以及被配置为计算 来自光学传感器信号的组织氧合测量,其中所述控制器,所述光学传感器和所述处理器协同工作以确定对应于最大组织氧合的所述治疗传递控制参数的设置。

    Tissue Oxygenation Monitoring in Heart Failure
    5.
    发明申请
    Tissue Oxygenation Monitoring in Heart Failure 有权
    心力衰竭组织氧合监测

    公开(公告)号:US20100317942A1

    公开(公告)日:2010-12-16

    申请号:US12797816

    申请日:2010-06-10

    IPC分类号: A61B5/00

    CPC分类号: A61N1/36557

    摘要: A medical device system and associated method are used for monitoring a heart failure patient. A medical device for monitoring delivery of a therapy includes a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient, a therapy delivery module to deliver a therapy, and a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement.

    摘要翻译: 医疗器械系统和相关方法用于监测心力衰竭患者。 用于监测治疗递送的医疗装置包括传感器,其感测对应于患者的身体组织的体积的光衰减的光学传感器信号,用于递送治疗的治疗递送模块和被配置为计算第一组织氧合的处理器 在开始递送治疗之前从光学传感器信号进行的测量,在开始递送治疗之后从光学传感器信号计算第二组织氧合测量,比较第一和第二组织氧合测量,并确定递送的治疗是否为 成功地响应于第一次组织氧合测量和第二次组织氧合测量。

    Device and Method for Monitoring of Absolute Oxygen Saturation and Tissue Hemoglobin Concentration
    6.
    发明申请
    Device and Method for Monitoring of Absolute Oxygen Saturation and Tissue Hemoglobin Concentration 有权
    用于监测绝对氧饱和度和组织血红蛋白浓度的装置和方法

    公开(公告)号:US20100317939A1

    公开(公告)日:2010-12-16

    申请号:US12797770

    申请日:2010-06-10

    IPC分类号: A61B5/1455

    摘要: A method and medical device for detecting signals that detects emitted light scattered by a volume of tissue delivered along a first pathway and a second pathway different from the first pathway, detects emitted light scattered by a volume of tissue delivered along a third pathway and a fourth pathway different from the third pathway, determines a first uniformity corresponding to the emitted light detected along the first pathway and the second pathway, determines a second uniformity corresponding to the emitted light detected along third pathway and the fourth pathway, determines a total uniformity in response to the determined first uniformity and the determined second uniformity, and alters sensing by the device in response to the determined total uniformity.

    摘要翻译: 一种用于检测信号的方法和医疗装置,其检测由沿着第一路径传送的组织体积散射的发射光和不同于第一路径的第二路径的信号,检测由沿着第三路径传送的组织体积散射的发射光, 确定与沿着第一路径和第二路径检测到的发射光相对应的第一均匀度,确定对应于沿着第三路径和第四路径检测的发射光的第二均匀度,确定响应中的总均匀性 到所确定的第一均匀性和确定的第二均匀性,并且改变由所述装置响应于所确定的总均匀性的感测。

    Contactless interconnect for transducers
    7.
    发明授权
    Contactless interconnect for transducers 失效
    用于传感器的非接触式互连

    公开(公告)号:US07684872B2

    公开(公告)日:2010-03-23

    申请号:US11380315

    申请日:2006-04-26

    IPC分类号: A61N1/08

    摘要: A medical device for implantation within a patient comprising a lead body including a conductor within the lead body and a transducer supported by the lead body. The conductor is electrically coupled to the transducer by a conductive fluid, paste or gel. The conductive fluid, paste or gel may be contained within a well in the lead body. The transducer may be a MEMS chip and/or an integrated circuit and may perform any of a variety of functions such as sensing physiological data.

    摘要翻译: 一种用于植入患者体内的医疗装置,包括:引线体,其包括引线体内的导体;以及由引线体支撑的换能器。 导体通过导电流体,糊剂或凝胶电耦合到换能器。 导电流体,糊状物或凝胶可以包含在引线体内的阱中。 换能器可以是MEMS芯片和/或集成电路,并且可以执行诸如感测生理数据的各种功能中的任何一种。

    Shock reduction using absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction
    8.
    发明授权
    Shock reduction using absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
    使用绝对校准的组织氧饱和度和总血红蛋白体积分数进行减震

    公开(公告)号:US08391979B2

    公开(公告)日:2013-03-05

    申请号:US12797793

    申请日:2010-06-10

    IPC分类号: A61N1/00

    摘要: An implantable medical device that includes an optical sensor for providing a signal corresponding to light attenuation by a volume of blood perfused tissue, a control module coupled to the optical sensor controlling the light emitted by the optical sensor, a monitoring module receiving an optical sensor output signal and measuring light attenuation, a tissue electrode for stimulating the volume of blood perfused tissue, a pulse generator coupled to the tissue electrode for delivering electrical stimulation to the volume of blood-perfused tissue, and a processor coupled to the cardiac electrode and the monitoring module and configured to detect an arrhythmia in response to the depolarization signals, compute a tissue oxygenation measurement and control the pulse generator to deliver electrical stimulation to the volume of blood-perfused tissue in response to detecting the arrhythmia, and detect a hemodynamic status of the arrhythmia in response to at least one of a detected rate of tissue oxygenation decline and a detected rate of tissue oxygenation recovery.

    摘要翻译: 一种可植入医疗装置,其包括:光学传感器,用于通过一定量的血液灌注组织提供对应于光衰减的信号;耦合到所述光学传感器的控制模块,所述控制模块控制由所述光学传感器发射的光;监测模块,其接收光学传感器输出 信号和测量光衰减的组织电极,用于刺激血液灌注组织的体积的组织电极,耦合到组织电极的脉冲发生器,用于向血液灌注组织的体积输送电刺激;以及处理器,其耦合到心脏电极和监测 模块并且被配置为响应于去极化信号检测心律失常,计算组织氧合测量并控制脉冲发生器以响应于检测到心律失常而向血液灌注组织的体积递送电刺激,并且检测血液动力学状态 响应于检测到的tis的速率中的至少一种的心律失常 检测氧合反应的下降和组织氧合恢复率。

    Implantable tissue perfusion sensing system and method
    10.
    发明授权
    Implantable tissue perfusion sensing system and method 有权
    植入式组织灌注感应系统及方法

    公开(公告)号:US08165662B2

    公开(公告)日:2012-04-24

    申请号:US12039281

    申请日:2008-02-28

    IPC分类号: A61B6/00

    摘要: A medical device for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, and generates a blood volume index in response to a light source of the plurality of light sources emitting light at an isobestic wavelength. The blood volume index is then utilized to verify the identifying of the cardiac event.

    摘要翻译: 一种用于感测心脏事件的医疗装置,其包括感测用于识别心脏事件的心脏信号的多个电极,能够发射多个波长的光的多个光源以及检测发射光的检测器。 处理器响应于由检测器检测到的发射光来确定多个光测量,并且响应于以异常波长发射光的多个光源的光源产生血液体积指数。 然后利用血容量指数来验证心脏事件的识别。