METHODS FOR MAINTAINING THE PATENCY OF COLLATERAL CHANNELS IN THE LUNGS USING CRYO-ENERGY
    41.
    发明申请
    METHODS FOR MAINTAINING THE PATENCY OF COLLATERAL CHANNELS IN THE LUNGS USING CRYO-ENERGY 审中-公开
    使用CRYO-ENERGY维持肺内通道的通知方法

    公开(公告)号:US20090076491A1

    公开(公告)日:2009-03-19

    申请号:US12233916

    申请日:2008-09-19

    IPC分类号: A61B18/02 A61B10/00

    摘要: The methods disclosed herein are directed to altering gaseous flow within a lung to improve the expiration cycle of, for instance, an individual having Chronic Obstructive Pulmonary Disease. More particularly, these methods produce and maintain collateral openings or channels through the airway wall so that expired air is able to pass directly out of the lung tissue to facilitate both the exchange of oxygen ultimately into the blood and/or to decompress hyper-inflated lungs. Devices and methods apply cryo-energy to maintain the patency of the surgically created openings.

    摘要翻译: 本文公开的方法旨在改变肺内的气流以改善例如具有慢性阻塞性肺疾病的个体的呼气循环。 更具体地说,这些方法产生和维持通过气道壁的侧支开口或通道,使得呼出的空气能够直接从肺组织中流出,以促进氧气最终进入血液和/或减压超膨胀肺 。 装置和方法应用低温能量以维持外科手术所产生的开口的通畅。

    Devices and methods for percutaneous repair of the mitral valve via the coronary sinus
    42.
    发明授权
    Devices and methods for percutaneous repair of the mitral valve via the coronary sinus 有权
    通过冠状窦经皮修复二尖瓣的装置和方法

    公开(公告)号:US07500989B2

    公开(公告)日:2009-03-10

    申请号:US11144521

    申请日:2005-06-03

    IPC分类号: A61F2/24

    CPC分类号: A61F2/2451

    摘要: Devices and methods for treating mitral regurgitation by reshaping the mitral annulus in a heart. One preferred device for reshaping the mitral annulus is provided as an elongate body having dimensions as to be insertable into a coronary sinus. The elongate body includes a proximal frame having a proximal anchor and a distal frame having a distal anchor. A ratcheting strip is attached to the distal frame and an accepting member is attached to the proximal frame, wherein the accepting member is adapted for engagement with the ratcheting strip. An actuating member is provided for pulling the ratcheting strip relative to the proximal anchor after deployment in the coronary sinus. In one preferred embodiment, the ratcheting strip is pulled through the proximal anchor for pulling the proximal and distal anchors together, thereby reshaping the mitral annulus.

    摘要翻译: 通过重塑心脏二尖瓣环来治疗二尖瓣反流的装置和方法。 一种用于重塑二尖瓣环的优选装置被提供为具有可插入冠状窦的尺寸的细长体。 细长体包括具有近端锚固件和具有远侧锚固件的远侧框架的近端框架。 棘轮条附接到远端框架,并且接收构件附接到近侧框架,其中接纳构件适于与棘轮条接合。 提供致动构件用于在部署在冠状窦中之后拉动棘轮条相对于近端锚固件。 在一个优选实施例中,棘轮带被拉动通过近端锚固件,用于将近端和远端锚固件拉在一起,从而重新形成二尖瓣环。

    Short sleeve stent delivery catheter and methods
    43.
    发明授权
    Short sleeve stent delivery catheter and methods 失效
    短袖支架输送导管及方法

    公开(公告)号:US07387639B2

    公开(公告)日:2008-06-17

    申请号:US09860744

    申请日:2001-05-18

    IPC分类号: A61F2/82

    CPC分类号: A61F2/958 A61F2/856 A61F2/954

    摘要: A stent delivery catheter comprises a catheter body having a proximal end, a distal end, and a guidewire lumen extending from the distal end to at least part way between the proximal end and the distal end. A balloon is disposed over the catheter body near the distal end, and a stent is positioned over the balloon. The stent has a proximal end, a distal end, and a side opening between the proximal end and the distal end. A side sheath is coupled to the catheter body and has a proximal end, a distal end, and a guidewire lumen extending between the proximal end and the distal end. The proximal end of the side sheath is located between the proximal end of the catheter body and the balloon, and the side sheath exits out of the side opening of the stent.

    摘要翻译: 支架输送导管包括具有近端,远端和从远端延伸到近端和远端之间至少部分方向的导丝管的导管主体。 气囊在远端附近设置在导管主体上方,支架位于气囊上方。 支架具有近端,远端和在近端和远端之间的侧开口。 侧护套耦合到导管主体并且具有近端,远端和在近端和远端之间延伸的导丝管腔。 侧护套的近端位于导管主体的近端和气囊之间,侧鞘从支架的侧开口离开。

    DIAGNOSTIC KIT TO ASSIST WITH HEART VALVE ANNULUS ADJUSTMENT
    44.
    发明申请
    DIAGNOSTIC KIT TO ASSIST WITH HEART VALVE ANNULUS ADJUSTMENT 有权
    诊断工具包以帮助心脏瓣膜调整

    公开(公告)号:US20070168023A1

    公开(公告)日:2007-07-19

    申请号:US11689310

    申请日:2007-03-21

    IPC分类号: A61F2/24

    摘要: A diagnostic device for determining the amount of change required in a coronary sinus to reduce valve regurgitation. The device includes a distal tube having a distal anchor at a distal end portion of the distal tube, a proximal tube having a proximal anchor at a distal end portion of the proximal tube, and an adjustor to move the distal tube relative to the proximal tube. The proximal tube and the distal tube together form a telescoping elongate body adapted to fit within the coronary sinus, and the device includes a scale to measure the movement of the distal anchor relative to the proximal anchor.

    摘要翻译: 用于确定冠状窦所需的变化量以减少瓣膜反流的诊断装置。 该装置包括远端管,远侧管位于远端管的远端部分处,近端管具有位于近端管的远端部分处的近端锚固件,以及用于相对于近端管移动远侧管的调节器 。 近端管和远端管一起形成适于装配在冠状窦内的伸缩式细长体,并且该装置包括用于测量远端锚固体相对于近端锚的运动的标尺。

    System and method for delivering a mitral valve repair device
    45.
    发明申请
    System and method for delivering a mitral valve repair device 审中-公开
    用于输送二尖瓣修复装置的系统和方法

    公开(公告)号:US20070073391A1

    公开(公告)日:2007-03-29

    申请号:US11238853

    申请日:2005-09-28

    IPC分类号: A61F2/24 A61F2/84

    摘要: A system and method is provided for treating a mitral valve. The method preferably includes advancing a guide catheter to an ostium of the coronary sinus and advancing a delivery catheter containing a medical implant through the guide catheter and into the coronary sinus. The delivery catheter has an inner member on which the medical implant is held and an outer sheath which is retractable for deploying and releasing the medical implant. In one embodiment, the medical implant has proximal and distal anchors and a bridge containing resorbable material. The inner member may have a flexible sleeve for gripping and holding a portion of the outer sheath, thereby providing a releasable attachment mechanism. In another embodiment, the inner member may include an inflatable balloon having a tapered distal region which extends from the outer sheath for providing an atraumatic tip. The inflatable balloon may also be used to expand the medical implant and to grip the outer sheath.

    摘要翻译: 提供了一种用于治疗二尖瓣的系统和方法。 该方法优选地包括将引导导管推进到冠状窦的口,并且将包含医用植入物的输送导管通过引导导管推入冠状窦。 输送导管具有保持医用植入物的内部构件和可伸缩以用于展开和释放医用植入物的外护套。 在一个实施例中,医疗植入物具有近端和远端锚固件以及包含可再吸收材料的桥。 内部构件可以具有用于夹持和保持外护套的一部分的柔性套筒,从而提供可释放的附接机构。 在另一个实施例中,内部构件可以包括具有锥形远侧区域的可膨胀气囊,该远端区域从外护套延伸以提供无创尖端。 可充气气囊也可以用于扩展医用植入物并且夹紧外护套。

    Superelastic guiding member
    48.
    发明授权
    Superelastic guiding member 有权
    超弹性引导构件

    公开(公告)号:US06280539B1

    公开(公告)日:2001-08-28

    申请号:US09498695

    申请日:2000-02-07

    IPC分类号: C22C1903

    摘要: An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

    摘要翻译: 改进的引导构件用于体腔内,具有超弹性特征的独特组合。 超弹性合金材料具有由约30%至约52%(原子)钛和约38%至52%的镍组成的组成,并且可以具有一种或多种选自铁,钴,铂,钯, 钒,铜,锆,铪和铌。 对合金材料进行热机械加工,其包括约10至约75%的最终冷加工,然后在约450℃至约600℃,优选约475℃至约550℃的温度下进行热处理。 在热处理之前,冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50%的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变,对于具有至少约4的广泛可恢复应变的管状构件,具有超过70ksi %相变。 获得基本上无鞭状产品。

    Flexible housing for intracorporeal use
    49.
    发明授权
    Flexible housing for intracorporeal use 失效
    弹性房屋用于体内使用

    公开(公告)号:US5776114A

    公开(公告)日:1998-07-07

    申请号:US590206

    申请日:1996-01-23

    摘要: An elongated flexible housing for an atherectomy or other intracorporeal catheter which is formed of a shape memory alloy such ass an alloy formed predominantly of NiTi intermetallic compound. The housing preferably has an inner chamber with a tissue cutter or other diagnostic or therapeutic system provided within the chamber to sever stenotic material which is urged into the chamber through a opening or window in the housing. In one embodiment the housing has at least one section which is relatively flexible with adjacent sections which are relatively stiff to provide an increase in the overall flexibility of the housing.

    摘要翻译: 一种用于粥样斑块切除术或其他体内导管的细长柔性外壳,其由形状记忆合金形成,例如主要由NiTi金属间化合物形成的合金。 壳体优选地具有内室,其具有设置在腔室内的组织切割器或其它诊断或治疗系统,以切断通过壳体中的开口或窗口被推入腔室的狭窄材料。 在一个实施例中,壳体具有至少一个与邻近部分相对柔性的部分,其相对较硬,以提供壳体的整体柔性的增加。