公开(公告)号：US20070288090A1

公开(公告)日：2007-12-13

申请号：US11841782

申请日：2007-08-20

申请人： Jan Solem ,  Per Kimblad

发明人： Jan Solem ,  Per Kimblad

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  A61B17/00234 ,  A61B2017/00243 ,  A61B2017/00867 ,  A61F2002/826 ,  Y10S623/903

摘要： A device for treatment of mitral annulus dilatation comprises an elongate body having two states. In a first of these states the elongate body is insertable into the coronary sinus and has a shape adapting to the shape of the coronary sinus. When positioned in the coronary sinus, the elongate body is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.

摘要翻译： 用于治疗二尖瓣环扩张的装置包括具有两种状态的细长体。 在这些状态中的第一个状态下，细长体可插入冠状窦，并且具有适应冠状窦形状的形状。 当定位在冠状窦中时，假设缩小的曲率半径，细长体可转移到第二状态，由此降低冠状窦的曲率半径和曲率半径以及二尖瓣环的圆周。

公开(公告)号：US20050080483A1

公开(公告)日：2005-04-14

申请号：US10500188

申请日：2002-12-20

申请人： Jan Solem ,  Per Kimblad ,  Randolf Oepen ,  Bodo Quint ,  Gerd Seibold ,  Kenneth Michlitsch ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Ib Joergensen ,  Stevan Nielsen

发明人： Jan Solem ,  Per Kimblad ,  Randolf Oepen ,  Bodo Quint ,  Gerd Seibold ,  Kenneth Michlitsch ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Ib Joergensen ,  Stevan Nielsen

IPC分类号： A61F2/02 ,  A61F2/04 ,  A61F2/07 ,  A61F2/24 ,  A61F2/26 ,  A61F2/82 ,  A61F2/848

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： A device for reshaping a cardiac valve (26), which is elongate and has such dimensions as to be insertable into a cardiac vessel (24). The device has two states, in a first state (K) of which the device has a shape that is adaptable to the shape of the vessel (24), and to the second state (k′) of which the device is transferable from said first state (K). Further, the device comprises a fixing means (22,23;22a,23a) for fixing the ends of the device within the vessel (24), when the device is first positioned therein, a shape-changing member (20;20a) for transferring the device to the second state (K′) by reshaping it, and a delay means (21;21a) for delaying said reshaping until the fixing of the ends of the device has been reinforced by keeping said device in said first state (K) until the delay means (21;21a) is resorbed.

摘要翻译： 一种用于整形心脏瓣膜（26）的装置，其是细长的并且具有可插入心脏容器（24）的尺寸。 该装置具有两种状态，其处于第一状态（K），其装置具有适应于容器（24）的形状的形状，以及第二状态（k'），其中装置可从所述第二状态 第一个状态（K）。 此外，该装置包括固定装置（22,23; 22a，23a），用于当装置首先定位在容器（24）内时将装置的端部固定，形状改变构件（20; 20a） 通过重新形成将装置转移到第二状态（K'），以及用于延迟所述重新成形的延迟装置（21; 21a），直到通过将所述装置保持在所述第一状态（K ），直到延迟装置（21; 21a）被再吸收。

公开(公告)号：US20050043792A1

公开(公告)日：2005-02-24

申请号：US10953047

申请日：2004-09-29

申请人： Jan Solem ,  Per Kimblad

发明人： Jan Solem ,  Per Kimblad

IPC分类号： A61B17/00 ,  A61F2/06 ,  A61F2/24 ,  A61F2/82 ,  A61F2/84 ,  A61F2/90 ,  A61M29/02

CPC分类号： A61F2/2451 ,  A61B17/00234 ,  A61B2017/00243 ,  A61B2017/00867 ,  A61F2002/826 ,  Y10S623/903

摘要： A device for treatment of mitral annulus dilatation comprises an elongate body having two states. In a first of these states the elongate body is insertable into the coronary sinus and has a shape adapting to the shape of the coronary sinus. When positioned in the coronary sinus, the elongate body is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.

摘要翻译： 用于治疗二尖瓣环扩张的装置包括具有两种状态的细长体。 在这些状态中的第一个状态下，细长体可插入冠状窦，并且具有适应冠状窦形状的形状。 当定位在冠状窦中时，假设缩小的曲率半径，细长体可转移到第二状态，由此降低冠状窦的曲率半径和曲率半径以及二尖瓣环的圆周。

公开(公告)号：US20070100442A1

公开(公告)日：2007-05-03

申请号：US11643352

申请日：2006-12-20

申请人： Jan Solem ,  Per Kimblad

发明人： Jan Solem ,  Per Kimblad

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  A61B17/00234 ,  A61B2017/00243 ,  A61B2017/00867 ,  A61F2002/826 ,  Y10S623/903

摘要： A device for treatment of mitral annulus dilatation comprises an elongate body having two states. In a first of these states the elongate body is insertable into the coronary sinus and has a shape adapting to the shape of the coronary sinus. When positioned in the coronary sinus, the elongate body is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.

摘要翻译： 用于治疗二尖瓣环扩张的装置包括具有两种状态的细长体。 在这些状态中的第一个状态下，细长体可插入冠状窦，并且具有适应冠状窦形状的形状。 当定位在冠状窦中时，假设缩小的曲率半径，细长体可转移到第二状态，由此降低冠状窦的曲率半径和曲率半径以及二尖瓣环的圆周。

公开(公告)号：US20070073391A1

公开(公告)日：2007-03-29

申请号：US11238853

申请日：2005-09-28

申请人： Henry Bourang ,  Rafael Pintor ,  Jan Solem ,  Per Kimblad ,  Jan Harnek ,  Sepehr Fariabi

发明人： Henry Bourang ,  Rafael Pintor ,  Jan Solem ,  Per Kimblad ,  Jan Harnek ,  Sepehr Fariabi

IPC分类号： A61F2/24 ,  A61F2/84

CPC分类号： A61F2/2451 ,  A61F2/2466 ,  A61F2210/0004

摘要： A system and method is provided for treating a mitral valve. The method preferably includes advancing a guide catheter to an ostium of the coronary sinus and advancing a delivery catheter containing a medical implant through the guide catheter and into the coronary sinus. The delivery catheter has an inner member on which the medical implant is held and an outer sheath which is retractable for deploying and releasing the medical implant. In one embodiment, the medical implant has proximal and distal anchors and a bridge containing resorbable material. The inner member may have a flexible sleeve for gripping and holding a portion of the outer sheath, thereby providing a releasable attachment mechanism. In another embodiment, the inner member may include an inflatable balloon having a tapered distal region which extends from the outer sheath for providing an atraumatic tip. The inflatable balloon may also be used to expand the medical implant and to grip the outer sheath.

摘要翻译： 提供了一种用于治疗二尖瓣的系统和方法。 该方法优选地包括将引导导管推进到冠状窦的口，并且将包含医用植入物的输送导管通过引导导管推入冠状窦。 输送导管具有保持医用植入物的内部构件和可伸缩以用于展开和释放医用植入物的外护套。 在一个实施例中，医疗植入物具有近端和远端锚固件以及包含可再吸收材料的桥。 内部构件可以具有用于夹持和保持外护套的一部分的柔性套筒，从而提供可释放的附接机构。 在另一个实施例中，内部构件可以包括具有锥形远侧区域的可膨胀气囊，该远端区域从外护套延伸以提供无创尖端。 可充气气囊也可以用于扩展医用植入物并且夹紧外护套。

公开(公告)号：US20060276890A1

公开(公告)日：2006-12-07

申请号：US11144521

申请日：2005-06-03

申请人： Jan Solem ,  Per Kimblad ,  Sepehr Fariabi ,  Stefan Schreck ,  Vaso Adzich ,  Octavian Iancea

发明人： Jan Solem ,  Per Kimblad ,  Sepehr Fariabi ,  Stefan Schreck ,  Vaso Adzich ,  Octavian Iancea

IPC分类号： A61F2/24

CPC分类号： A61F2/2451

摘要： Devices and methods for treating mitral regurgitation by reshaping the mitral annulus in a heart. One preferred device for reshaping the mitral annulus is provided as an elongate body having dimensions as to be insertable into a coronary sinus. The elongate body includes a proximal frame having a proximal anchor and a distal frame having a distal anchor. A ratcheting strip is attached to the distal frame and an accepting member is attached to the proximal frame, wherein the accepting member is adapted for engagement with the ratcheting strip. An actuating member is provided for pulling the ratcheting strip relative to the proximal anchor after deployment in the coronary sinus. In one preferred embodiment, the ratcheting strip is pulled through the proximal anchor for pulling the proximal and distal anchors together, thereby reshaping the mitral annulus.

公开(公告)号：US20060184230A1

公开(公告)日：2006-08-17

申请号：US11343382

申请日：2006-01-30

申请人： Jan Solem ,  Per Kimblad

发明人： Jan Solem ,  Per Kimblad

IPC分类号： A61F2/06

CPC分类号： A61F2/2451 ,  A61F2/07 ,  A61F2/2481 ,  A61F2/26 ,  A61F2002/043 ,  A61F2002/072 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/8483 ,  A61F2210/0004

摘要： A delivery system for delivering a prosthetic heart valve to a native valve site within the human vasculature. The prosthetic valve is disposed on a balloon at the end of a balloon catheter. The balloon catheter passes through a delivery sleeve assembly and handle. A pull wire travels from the handle to a distal end of the delivery sleeve assembly. Actuation of the handle pulls on the pull wire, which causes openings in a slotted tube of the delivery sleeve assembly to close, thus causing the delivery sleeve assembly to bend. A stretchable cover is placed over the slotted tube for biasing the steerable catheter toward a straight position. Once advanced to the native valve site, the prosthetic valve is deployed by inflating the balloon.

摘要翻译： 用于将假体心脏瓣膜递送到人类脉管系统内的天然瓣膜部位的递送系统。 假体瓣膜设置在球囊导管末端的球囊上。 气囊导管穿过输送套筒组件和手柄。 拉线从手柄行进到输送套筒组件的远端。 手柄的致动拉动拉线，其导致输送套筒组件的开槽管中的开口关闭，从而导致输送套筒组件弯曲。 一个可拉伸的盖子被放置在开槽管上面，用于将可转向的导管偏向一个直的位置。 一旦进入本地瓣膜部位，通过使球囊膨胀来展开假体瓣膜。

公开(公告)号：US20060064118A1

公开(公告)日：2006-03-23

申请号：US11268385

申请日：2005-11-07

申请人： Per Kimblad

发明人： Per Kimblad

IPC分类号： A61B17/08

CPC分类号： A61B17/064 ,  A61B17/0644 ,  A61B17/122 ,  A61B2017/00243 ,  A61B2017/00783 ,  A61B2017/00867 ,  A61B2017/0641 ,  A61F2/2442

摘要： A device and method for treatment of atrioventricular regurgitation comprises a suturing device. The suturing device is configured to be introducible, via blood vessels leading to the heart, to two leaflets of the atrioventricular valve between the atrium and a corresponding ventricle of the heart. The suturing device is configured for binding together the two leaflets along the free edges of the leaflets. A method of using the device includes inserting the suturing device into a catheter, introducing the catheter to the heart and positioning a distal end of the catheter close to two leaflets of an atrioventricular valve, capturing the free edges of the two leaflets with the suturing device in its open state, binding together the two leaflets by transition of the suturing device into its closed state, and retracting the catheter from the heart. As a result, the closing of the valve is improved.

摘要翻译： 用于治疗房室反流的装置和方法包括缝合装置。 缝合装置被构造成通过导致心脏的血管被引入到房间和心脏的相应心室之间的房室瓣的两个小叶。 缝合装置被配置成沿着传单的自由边缘将两个传单捆绑在一起。 使用该装置的方法包括将缝合装置插入导管中，将导管引入心脏并将导管的远端定位在房室瓣的两个小叶上，用缝合装置捕获两个小叶的自由边缘 在其打开状态下，通过缝合装置的过渡到其闭合状态并且从心脏缩回导管，将两个传单捆绑在一起。 结果，阀的关闭得到改善。

公开(公告)号：US20050177228A1

公开(公告)日：2005-08-11

申请号：US11014273

申请日：2004-12-15

申请人： Jan Solem ,  Per Kimblad ,  Stevan Nielsen ,  Ib Joergenson ,  Bodo Quint ,  Gerd Seibold ,  Randolf Oepen ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Stefan Schreck ,  Sepehr Fariabi ,  Tommy Conzelmann

发明人： Jan Solem ,  Per Kimblad ,  Stevan Nielsen ,  Ib Joergenson ,  Bodo Quint ,  Gerd Seibold ,  Randolf Oepen ,  Suk-Woo Ha ,  Karl-Ludwig Eckert ,  Stefan Schreck ,  Sepehr Fariabi ,  Tommy Conzelmann

IPC分类号： A61F2/24

CPC分类号： A61F2/2451

摘要： An elongate body including a proximal and distal anchor, and a bridge between the proximal and distal anchors. The bridge has an elongated state, having first axial length, and a shortened state, having a second axial length, wherein the second axial length is shorter than the first axial length. A resorbable thread may be woven into the bridge to hold the bridge in the elongated state and to delay the transfer of the bridge to the shortened state. In an additional embodiment, there may be one or more central anchors between the proximal and distal anchors with a bridge connecting adjacent anchors.

摘要翻译： 包括近端和远端锚固件的细长主体以及近端和远端锚固件之间的桥梁。 桥具有第一轴向长度的细长状态和具有第二轴向长度的缩短状态，其中第二轴向长度短于第一轴向长度。 可再吸收的线可以编织到桥中以将桥梁保持在细长状态，并且将桥的传递延迟到缩短状态。 在另外的实施例中，在近端和远端锚固件之间可以有一个或多个中心锚固件，其具有连接相邻锚固件的桥。