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    Devices and methods for percutaneous repair of the mitral valve via the coronary sinus
    2.
    发明授权
    Devices and methods for percutaneous repair of the mitral valve via the coronary sinus 有权
    通过冠状窦经皮修复二尖瓣的装置和方法

    公开(公告)号：US07500989B2

    公开(公告)日：2009-03-10

    申请号：US11144521

    申请日：2005-06-03

    申请人： Jan Otto Solem ,  Per Ola Kimblad ,  Sepehr Fariabi ,  Stefan Schreck ,  Vaso Adzich ,  Octavian Iancea

    发明人： Jan Otto Solem ,  Per Ola Kimblad ,  Sepehr Fariabi ,  Stefan Schreck ,  Vaso Adzich ,  Octavian Iancea

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451

    摘要： Devices and methods for treating mitral regurgitation by reshaping the mitral annulus in a heart. One preferred device for reshaping the mitral annulus is provided as an elongate body having dimensions as to be insertable into a coronary sinus. The elongate body includes a proximal frame having a proximal anchor and a distal frame having a distal anchor. A ratcheting strip is attached to the distal frame and an accepting member is attached to the proximal frame, wherein the accepting member is adapted for engagement with the ratcheting strip. An actuating member is provided for pulling the ratcheting strip relative to the proximal anchor after deployment in the coronary sinus. In one preferred embodiment, the ratcheting strip is pulled through the proximal anchor for pulling the proximal and distal anchors together, thereby reshaping the mitral annulus.

    摘要翻译： 通过重塑心脏二尖瓣环来治疗二尖瓣反流的装置和方法。 一种用于重塑二尖瓣环的优选装置被提供为具有可插入冠状窦的尺寸的细长体。 细长体包括具有近端锚固件和具有远侧锚固件的远侧框架的近端框架。 棘轮条附接到远端框架，并且接收构件附接到近侧框架，其中接纳构件适于与棘轮条接合。 提供致动构件用于在部署在冠状窦中之后拉动棘轮条相对于近端锚固件。 在一个优选实施例中，棘轮带被拉动通过近端锚固件，用于将近端和远端锚固件拉在一起，从而重新形成二尖瓣环。

    System and method for delivering a mitral valve repair device
    4.
    发明申请
    System and method for delivering a mitral valve repair device 审中-公开
    用于输送二尖瓣修复装置的系统和方法

    公开(公告)号：US20070073391A1

    公开(公告)日：2007-03-29

    申请号：US11238853

    申请日：2005-09-28

    申请人： Henry Bourang ,  Rafael Pintor ,  Jan Solem ,  Per Kimblad ,  Jan Harnek ,  Sepehr Fariabi

    发明人： Henry Bourang ,  Rafael Pintor ,  Jan Solem ,  Per Kimblad ,  Jan Harnek ,  Sepehr Fariabi

    IPC分类号： A61F2/24 ,  A61F2/84

    CPC分类号： A61F2/2451 ,  A61F2/2466 ,  A61F2210/0004

    摘要： A system and method is provided for treating a mitral valve. The method preferably includes advancing a guide catheter to an ostium of the coronary sinus and advancing a delivery catheter containing a medical implant through the guide catheter and into the coronary sinus. The delivery catheter has an inner member on which the medical implant is held and an outer sheath which is retractable for deploying and releasing the medical implant. In one embodiment, the medical implant has proximal and distal anchors and a bridge containing resorbable material. The inner member may have a flexible sleeve for gripping and holding a portion of the outer sheath, thereby providing a releasable attachment mechanism. In another embodiment, the inner member may include an inflatable balloon having a tapered distal region which extends from the outer sheath for providing an atraumatic tip. The inflatable balloon may also be used to expand the medical implant and to grip the outer sheath.

    摘要翻译： 提供了一种用于治疗二尖瓣的系统和方法。 该方法优选地包括将引导导管推进到冠状窦的口，并且将包含医用植入物的输送导管通过引导导管推入冠状窦。 输送导管具有保持医用植入物的内部构件和可伸缩以用于展开和释放医用植入物的外护套。 在一个实施例中，医疗植入物具有近端和远端锚固件以及包含可再吸收材料的桥。 内部构件可以具有用于夹持和保持外护套的一部分的柔性套筒，从而提供可释放的附接机构。 在另一个实施例中，内部构件可以包括具有锥形远侧区域的可膨胀气囊，该远端区域从外护套延伸以提供无创尖端。 可充气气囊也可以用于扩展医用植入物并且夹紧外护套。

    Diagnostic kit to assist with heart valve annulus adjustment
    5.
    发明申请
    Diagnostic kit to assist with heart valve annulus adjustment 有权
    诊断套件，以协助心脏瓣膜环调整

    公开(公告)号：US20060129051A1

    公开(公告)日：2006-06-15

    申请号：US11008055

    申请日：2004-12-09

    申请人： Stanton Rowe ,  Henry Bourang ,  Sepehr Fariabi ,  Jan Solem

    发明人： Stanton Rowe ,  Henry Bourang ,  Sepehr Fariabi ,  Jan Solem

    IPC分类号： A61B5/02

    CPC分类号： A61F2/2451 ,  A61B1/00082 ,  A61B5/064 ,  A61B8/06 ,  A61B8/12

    摘要： A diagnostic device for determining the amount of change required in a coronary sinus to reduce valve regurgitation. The device includes a distal tube having a distal anchor at a distal end portion of the distal tube, a proximal tube having a proximal anchor at a distal end portion of the proximal tube, and an adjustor to move the distal tube relative to the proximal tube. The proximal tube and the distal tube together form a telescoping elongate body adapted to fit within the coronary sinus, and the device includes a scale to measure the movement of the distal anchor relative to the proximal anchor.

    摘要翻译： 用于确定冠状窦所需的变化量以减少瓣膜反流的诊断装置。 该装置包括远端管，远侧管位于远端管的远端部分处，近端管具有位于近端管的远端部分处的近端锚固件，以及用于相对于近端管移动远侧管的调节器 。 近端管和远端管一起形成适于装配在冠状窦内的伸缩式细长体，并且该装置包括用于测量远端锚固体相对于近端锚的运动的标尺。

    DIAGNOSTIC KIT TO ASSIST WITH HEART VALVE ANNULUS ADJUSTMENT
    7.
    发明申请
    DIAGNOSTIC KIT TO ASSIST WITH HEART VALVE ANNULUS ADJUSTMENT 有权
    诊断工具包以帮助心脏瓣膜调整

    公开(公告)号：US20070168023A1

    公开(公告)日：2007-07-19

    申请号：US11689310

    申请日：2007-03-21

    申请人： Stanton Rowe ,  Henry Bourang ,  Sepehr Fariabi ,  Jan Solem

    发明人： Stanton Rowe ,  Henry Bourang ,  Sepehr Fariabi ,  Jan Solem

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61B1/00082 ,  A61B5/064 ,  A61B8/06 ,  A61B8/12

    摘要： A diagnostic device for determining the amount of change required in a coronary sinus to reduce valve regurgitation. The device includes a distal tube having a distal anchor at a distal end portion of the distal tube, a proximal tube having a proximal anchor at a distal end portion of the proximal tube, and an adjustor to move the distal tube relative to the proximal tube. The proximal tube and the distal tube together form a telescoping elongate body adapted to fit within the coronary sinus, and the device includes a scale to measure the movement of the distal anchor relative to the proximal anchor.

    摘要翻译： 用于确定冠状窦所需的变化量以减少瓣膜反流的诊断装置。 该装置包括远端管，远侧管位于远端管的远端部分处，近端管具有位于近端管的远端部分处的近端锚固件，以及用于相对于近端管移动远侧管的调节器 。 近端管和远端管一起形成适于装配在冠状窦内的伸缩式细长体，并且该装置包括用于测量远端锚固体相对于近端锚的运动的标尺。

    Superelastic guiding member
    10.
    发明授权
    Superelastic guiding member 失效

    公开(公告)号：US07244319B2

    公开(公告)日：2007-07-17

    申请号：US10291930

    申请日：2002-11-11

    申请人： Robert M. Abrams ,  Sepehr Fariabi

    发明人： Robert M. Abrams ,  Sepehr Fariabi

    IPC分类号： A61F2/86

    CPC分类号： A61L31/14 ,  A61L31/022 ,  A61L2400/16 ,  A61M25/09 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

    摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.