公开(公告)号：US08500682B2

公开(公告)日：2013-08-06

申请号：US13119266

申请日：2009-09-18

申请人： Richard A. Cronenberg ,  Asif Fayyaz ,  Atul Patel ,  Lionel Vedrine

发明人： Richard A. Cronenberg ,  Asif Fayyaz ,  Atul Patel ,  Lionel Vedrine

IPC分类号： A61M37/00 ,  A61M5/20

CPC分类号： A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/2448 ,  A61M5/3129 ,  A61M5/31553 ,  A61M5/3156

摘要： A medical injector is provided herein having a body; a reservoir containing first and second mixable component; a stopper; a plunger; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance so that the stopper traverses at least a predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for autoreconstitution with subsequent dose setting and autoplunger activation being activated by separate triggers.

摘要翻译： 本发明提供一种具有身体的医用注射器; 包含第一和第二可混合组分的储存器; 塞子 柱塞 设置成使柱塞前进的弹簧; 第一可释放保持器，用于将柱塞可释放地保持在第一状态，抵抗弹簧的力; 用于使第一可释放保持器释放柱塞的第一触发器; 第二可释放保持器，用于将所述柱塞可释放地保持在抵抗所述弹簧的力的第二状态; 以及用于使第二可释放保持器释放柱塞的第二触发器。 弹簧使柱塞前进，使得止动件至少延伸一定程度的前进，从而引起第一和第二可混合部件的混合。 有利地，对于本发明，提供了一种医疗注射器，其允许自动重新配置，随后的剂量设定和自动活动激活由单独的触发器激活。

公开(公告)号：US20120209171A1

公开(公告)日：2012-08-16

申请号：US12679508

申请日：2008-09-29

申请人： Lionel Vedrine ,  Roger W. Groskopf ,  Matthew Sweeney ,  Talpade A. Dnyanesh ,  Min Wei ,  Ruane Jeter

发明人： Lionel Vedrine ,  Roger W. Groskopf ,  Matthew Sweeney ,  Talpade A. Dnyanesh ,  Min Wei ,  Ruane Jeter

IPC分类号： A61J1/20 ,  A61M5/31

CPC分类号： A61M5/284 ,  A61M5/2448 ,  A61M5/288 ,  A61M5/3134 ,  A61M5/31513 ,  A61M5/345 ,  A61M5/347 ,  A61M5/348 ,  A61M2005/3104 ,  A61M2005/31516 ,  B65B3/003

摘要： A cartridge or injector for holding and mixing a medical product is provided herein including a tubular body having a cylindrical wall having first and second opposing ends. The wall includes inner and outer surfaces with the inner surface having a generally constant cross-section along at least a drug mixing area. A first stopper is slidably disposed within the wall between the first and second ends, the first stopper defining a liquid-tight seal with the inner surface. A second stopper is slidably disposed within the wall between the first stopper and the first end, the second stopper defining a liquid-tight seal with the inner surface. A flexible insert is disposed at or in proximity to the second end, the insert forming a liquid-tight seal with the wall, the insert being pierceable by a medical needle or other piercing instrument. A rigid retainer is fixed to the wall having an opening therein for providing access to the insert for piercing by a medical needle. The insert extends into the retainer and forms a liquid-tight seal across the opening. Advantageously, with the subject invention, a reconstitution assembly may be provided which has a sufficiently large distal opening during assembly which allows a dry component to be introduced into the device in a dry state.

摘要翻译： 本文提供了用于保持和混合医疗产品的药筒或注射器，其包括具有圆柱形壁的管状体，其具有第一和第二相对端。 该壁包括内表面和外表面，其中内表面至少沿着药物混合区域具有大致恒定的横截面。 第一止动件可滑动地设置在第一和第二端之间的壁内，第一止动件限定与内表面的液密密封。 第二止动件可滑动地设置在第一止挡件和第一端之间的壁内，第二止动件限定与内表面的液密密封。 柔性插入件设置在第二端处或附近，插入件与壁形成液密密封，插入件可被医用针或其它穿刺器械刺穿。 刚性保持器固定到其上具有开口的壁上，用于提供通过医用针穿刺插入物的通路。 插入件延伸到保持器中并且跨越开口形成液密密封。 有利地，对于本发明，可以提供在组装期间具有足够大的远端开口的重构组件，其允许在干燥状态下将干燥部件引入装置。

公开(公告)号：US08137313B2

公开(公告)日：2012-03-20

申请号：US10573226

申请日：2004-09-14

申请人： Lionel Vedrine

发明人： Lionel Vedrine

IPC分类号： A61M5/20

CPC分类号： A61M5/2429 ,  A61M5/2033 ,  A61M5/2459 ,  A61M5/326 ,  A61M2005/3263

摘要： A medical device for the injection of a product. The device includes a body receiving an injection needle and a container containing the product to be injected; an arrangement for holding the needle in an injection position; an arrangement for holding the container in a position permitting injection; and, a piston engaged in the container. The device also includes first and second actuators which make it possible, at the end of the injection, to respectively release the arrangement for holding the needle before, or simultaneously to, the release of the arrangement for holding the container. A container support is mounted slidably on the body and is displaceable relative to the latter in order to perform the injection. The container support is held in a standby position before injection with the needle being held in the injection position.

摘要翻译： 用于注射产品的医疗设备。 该装置包括接收注射针的主体和容纳待注射的产品的容器; 用于将针保持在注射位置的布置; 用于将容器保持在允许注射的位置的布置; 以及接合在容器中的活塞。 该装置还包括第一和第二致动器，其使得在注射结束时可以分别释放用于保持针头的装置，或同时释放用于保持容器的装置。 容器支撑件可滑动地安装在主体上，并且可相对于主体移动以执行注射。 在注射之前，容器支撑件保持在待机位置，其中针被保持在注射位置。

公开(公告)号：US20110213315A1

公开(公告)日：2011-09-01

申请号：US13063792

申请日：2009-09-18

申请人： Matthew D. Sweeney ,  Richard A. Cronenberg ,  Lionel Vedrine

发明人： Matthew D. Sweeney ,  Richard A. Cronenberg ,  Lionel Vedrine

IPC分类号： A61M5/315

CPC分类号： A61M5/2448 ,  A61M5/2033 ,  A61M5/3146 ,  A61M5/31553 ,  A61M5/3156 ,  A61M2005/2073 ,  A61M2005/2451

摘要： In one aspect, a medical injector is provided herein which includes a body; a displaceable plunger disposed in the body; a spring disposed to advance the plunger; a releasable retainer for retaining the plunger in a first state against force of the spring; and, a sleeve disposed on the body, the sleeve being slidable relative to the body. Sliding movement of the sleeve over a predetermined extent relative to the body results in the releasable retainer releasing the plunger thereby allowing the spring to advance the plunger. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon sliding movement of the sleeve, thereby minimizing premature or failed activations.

摘要翻译： 在一个方面，本文提供了一种医用注射器，其包括主体; 设置在本体中的可移位柱塞; 设置成使柱塞前进的弹簧; 可释放的保持器，用于将柱塞保持在第一状态以抵抗弹簧的力; 以及设置在所述主体上的套筒，所述套筒可相对于所述主体滑动。 套筒相对于主体的预定范围的滑动使得可释放的保持器释放柱塞，从而允许弹簧推进柱塞。 有利地，本发明提供一种具有自动柱塞驱动器的医用注射器，其在套筒的滑动运动时触发，从而最小化过早或失效的激活。

公开(公告)号：US20110049265A1

公开(公告)日：2011-03-03

申请号：US12867920

申请日：2009-02-02

申请人： Lionel Vedrine

发明人： Lionel Vedrine

IPC分类号： B05B11/00 ,  B23P19/02

CPC分类号： A61M11/00 ,  A61M11/007 ,  A61M15/0025 ,  B05B11/0027 ,  B65D41/3409 ,  Y10T29/49945

摘要： This sprayer (1) includes a container (2) of product to be sprayed, provided with a delivery opening for this product, and a spraying assembly (3), said spraying assembly (3) being in fluid communication with this delivery opening and being securable onto this container (2) by insertion about a mounting axis, this spraying assembly (3) including a sprayer body (6) delimiting a proximalarea (14) conformed so as to be securable to said container (2), and including a distal wall (10), transverse to said mounting axis, in which a spraying aperture (11) is arranged, and a cap (7) intended to be mounted on the sprayer body (6). According to the invention, the cap (7) includes a wall (20) transverse to said mounting axis, being sufficiently rigid so as to bear without substantial damaging a force from 50 to 100 N necessary to secure this sprayer body (6) to said container (2) and thus to enable the transmission to said sprayer body (6) of this force.

摘要翻译： 该喷雾器（1）包括一个待喷射产品的容器（2），该容器（2）具有用于该产品的输送开口和一个喷射组件（3），所述喷射组件（3）与该输送口流体连通， 该喷射组件（3）包括限定近端区域（14）的喷雾器本体（6），所述喷嘴主体（6）适于安装在所述容器（2）上，并且包括远端 横向于所述安装轴线的壁（10），其中布置有喷射孔（11），以及旨在安装在喷雾器主体（6）上的盖（7）。 根据本发明，盖（7）包括横向于所述安装轴线的壁（20），其具有足够的刚性，以便承受不会将该喷雾器本体（6）固定到所述安装轴上所需的50至100N的力 容器（2），从而能够向该喷雾器主体（6）传递该力。

公开(公告)号：US20090292257A1

公开(公告)日：2009-11-26

申请号：US12534186

申请日：2009-08-03

申请人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

发明人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

IPC分类号： A61M5/32

CPC分类号： A61M5/326 ,  A61M2005/3247 ,  A61M2005/3261

摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.

摘要翻译： 提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。 屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。 弹簧弹性地将护罩从缩回位置推向延伸位置。 止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。 注射器可滑动地联接到保持器，并且在护罩内延伸。 注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。 在保持器上设置有用于将护罩保持在延伸位置的凹处。

公开(公告)号：US07455661B2

公开(公告)日：2008-11-25

申请号：US10737627

申请日：2003-12-16

申请人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

发明人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

IPC分类号： A61M5/00

CPC分类号： A61M5/326 ,  A61M2005/3247 ,  A61M2005/3261

摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.

摘要翻译： 提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。 屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。 弹簧弹性地将护罩从缩回位置推向延伸位置。 止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。 注射器可滑动地联接到保持器，并且在护罩内延伸。 注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。 在保持器上设置有用于将护罩保持在延伸位置的凹处。

公开(公告)号：US20080183137A1

公开(公告)日：2008-07-31

申请号：US12098770

申请日：2008-04-07

申请人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

发明人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

IPC分类号： A61M5/32

CPC分类号： A61M5/326 ,  A61M2005/3247 ,  A61M2005/3261

摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.

摘要翻译： 提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。 屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。 弹簧弹性地将护罩从缩回位置推向延伸位置。 止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。 注射器可滑动地联接到保持器，并且在护罩内延伸。 注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。 在保持器上设置有用于将护罩保持在延伸位置的凹处。

公开(公告)号：US20070185460A1

公开(公告)日：2007-08-09

申请号：US10569618

申请日：2004-01-30

申请人： Lionel Vedrine ,  Paul Alchas ,  Peter Heyman ,  Laurent Barrelle ,  Marina Korisch

发明人： Lionel Vedrine ,  Paul Alchas ,  Peter Heyman ,  Laurent Barrelle ,  Marina Korisch

IPC分类号： A61M5/31 ,  A61M5/00

CPC分类号： A61M5/46 ,  A61M5/28 ,  A61M5/31511 ,  A61M5/321 ,  A61M5/343 ,  A61M5/349 ,  A61M5/425 ,  A61M2005/311

摘要： An intradermal injection device comprising a unitary body having an open distal end and a proximal end having a skin engaging surface defined thereon, a reservoir defined between the proximal and distal ends for accommodating a drug substance, and a channel defined at the proximal end of the unitary body and extending through, and distally from, the skin engaging surface to the reservoir. A needle cannula having a sharpened proximal end and a distal end may be provided in the channel. The needle cannula is secured in the channel with the distal end being in communication with the reservoir and the proximal end of the needle cannula extending from the skin engaging surface a distance in the range of about 0.5 mm to 3.0 mm such that the skin engaging surface limits penetration of the proximal end of the needle cannula to the dermis layer of the skin of a patient.

摘要翻译： 一种真皮内注射装置，包括具有敞开的远端的整体，具有限定在其上的皮肤接合表面的近端，限定在近端和远端之间用于容纳药物的储液器，以及限定在药物物质的近端的通道 整体并延伸穿过皮肤接合表面并向远端延伸到储存器。 具有尖锐的近端和远端的针管可以设置在通道中。 针插管被固定在通道中，其远端与储存器连通，并且针插管的近端从皮肤接合表面延伸出约0.5mm至3.0mm范围内的距离，使得皮肤接合表面 限制针插管的近端穿透到患者皮肤的真皮层。

公开(公告)号：US06622721B2

公开(公告)日：2003-09-23

申请号：US09829843

申请日：2001-04-10

申请人： Lionel Vedrine ,  Hubert Jansen ,  Jean Pierre Grimard ,  Michel Guillory

发明人： Lionel Vedrine ,  Hubert Jansen ,  Jean Pierre Grimard ,  Michel Guillory

IPC分类号： A61M1100

CPC分类号： B05B11/02 ,  A61M5/31591 ,  A61M11/06 ,  A61M15/0025 ,  A61M15/0065 ,  A61M15/08 ,  A61M2005/208 ,  A61M2205/073 ,  A61M2210/0618

摘要： A drug delivery system for administering preset doses of a substance such as a drug, vaccine or the like is provided. The drug delivery system includes a holder and a pre-filled drug container such as a syringe which is securely retained in the holder. The drug container includes a barrel for containing the substance, a movable stopper situated within the barrel, and a blunt end having an opening through which the substance within the barrel can be expelled. The holder includes a distal portion and a proximal portion, each configured to accommodate the drug container, with the distal portion being able to be assembled to the proximal portion, which acts as a plunger rod during activation of the delivery system. A plurality of slots are provided for controlling the delivery of a substance and extend axially along at least one portion of the holder whereby upon activation of the system, the portions of the holder move towards one another upon the application of a minimum force and the stopper moves a preselected axial distance to expel at least a portion of the substance from the drug container. One application is to a nasal drug container, where approximately equal doses of the substance are desired to be administered to each nostril of the patient.