公开(公告)号：US09084883B2

公开(公告)日：2015-07-21

申请号：US12704939

申请日：2010-02-12

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61N1/02 ,  A61N1/05 ,  A61N1/08

CPC classification number: A61N1/056 ,  A61N1/086

Abstract: A medical device lead includes a thin profile conductor assembly. A proximal connector includes a proximal end that is configured to couple the lead to a pulse generator. An insulative lead body extends distally from the proximal connector. The conductor assembly extends distally from the proximal end within the lead body and includes a non-conductive tubular core member that defines a lumen, an outer insulative layer, and a multilayer conductor between the tubular core member and the outer insulative layer. The multilayer conductor is electrically connected to the proximal connector and includes a first conductive layer adjacent to the tubular core member and a second conductive layer adjacent to the first conductive layer opposite the tubular core member. A conductivity of the second conductive layer is greater than a conductivity of the first conductive layer.

Abstract translation: 医疗器械引线包括薄型导体组件。 近端连接器包括被配置为将引线耦合到脉冲发生器的近端。 绝缘引线体从近端连接器向远侧延伸。 导体组件从引线主体内的近端向远侧延伸，并且包括在管芯和外绝缘层之间限定内腔，外绝缘层和多层导体的非导电管状芯构件。 所述多层导体电连接到所述近端连接器，并且包括与所述管状芯部件相邻的第一导电层和与所述管状芯部件相对的所述第一导电层相邻的第二导电层。 第二导电层的导电率大于第一导电层的导电率。

公开(公告)号：US08071155B2

公开(公告)日：2011-12-06

申请号：US11122583

申请日：2005-05-05

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: B05D3/06 ,  A61F2/06

CPC classification number: C03C8/00 ,  A61L31/082

Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a method includes diffusing a first element into a first portion of the medical device. The first element includes carbon, hydrogen, nitrogen, oxygen, or combinations thereof. The first portion includes a refractory material.

Abstract translation: 公开了诸如支架的医疗装置和制造装置的方法。 在一些实施例中，一种方法包括将第一元件扩散到医疗装置的第一部分中。 第一元素包括碳，氢，氮，氧或它们的组合。 第一部分包括耐火材料。

公开(公告)号：US07988719B2

公开(公告)日：2011-08-02

申请号：US12842760

申请日：2010-07-23

Applicant: Eckhard Alt ,  Torsten Scheuermann ,  Michael Kuhling

Inventor： Eckhard Alt ,  Torsten Scheuermann ,  Michael Kuhling

IPC: A61F2/06

CPC classification number: A61L31/18 ,  A61B5/055 ,  A61B5/411 ,  A61F2/88 ,  A61F2/91 ,  A61F2210/0076 ,  A61F2250/0043 ,  A61L31/022 ,  A61L31/082 ,  G01R33/285 ,  G01R33/34046 ,  G01R33/34053 ,  G01R33/34069 ,  G01R33/34076 ,  G01R33/34084

Abstract: A stent is adapted to be implanted in a duct of a human body to maintain an open lumen at the implant site, and to allow viewing body tissue and fluids by magnetic resonance imaging (MRI) energy applied external to the body. The stent constitutes a metal scaffold. An electrical circuit resonant at the resonance frequency of the MRI energy is fabricated integral with the scaffold structure of the stent to promote viewing body properties within the lumen of the stent.

Abstract translation: 支架适于植入人体的管道中，以在植入部位保持开放的腔，并且允许通过在身体外部施加的磁共振成像（MRI）能量观察体内组织和流体。 支架构成金属支架。 在MRI能量的共振频率下共振的电路与支架的支架结构一体制成，以促进支架内腔内的观察体特性。

公开(公告)号：US20100241204A1

公开(公告)日：2010-09-23

申请号：US12703544

申请日：2010-02-10

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61N1/05 ,  B05D3/14

CPC classification number: A61N1/056 ,  A61B5/042 ,  A61B2562/0209

Abstract: The embodiments herein relate to an electrode having a porous coating including a fiber mesh, a multi-layer coating, and an outer coating, and a method of making the same. The various electrode coating embodiments include pores in the coating that prevent access by protein or cells while allowing for ion and/or liquid access.

Abstract translation: 本文的实施方案涉及具有包括纤维网，多层涂层和外涂层的多孔涂层的电极及其制造方法。 各种电极涂覆实施方案包括涂层中的孔，其阻止蛋白质或细胞进入，同时允许离子和/或液体进入。

公开(公告)号：US07604703B2

公开(公告)日：2009-10-20

申请号：US11417856

申请日：2006-05-03

Applicant: Torsten Scheuermann ,  Eckhard Alt

Inventor： Torsten Scheuermann ,  Eckhard Alt

IPC: C23C8/06 ,  A61F2/06 ,  C22F1/18

CPC classification number: A61L31/18 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/022 ,  A61L31/088

Abstract: In a process of fabricating a stent composed primarily of niobium alloyed with a trace amount of zirconium, tantalum, or titanium for hardening, the stent is annealed under vacuum in a substantially oxygen-free environment. The vacuum is preferably maintained at pressure less than 10−4 millibars, oxygen-content less than about 80 parts per million, and the annealing temperature exceeds 400° C. for at least one hour, and is preferably kept in a range from about 1100-1200° C. for several hours. This may be followed by applying a surface layer of oxide, such as iridium oxide, with a thickness of 299-300 nm to the stent.

Abstract translation: 在制造主要由铌合金化的用于硬化的锆，钽或钛的支架的制造过程中，支架在基本上无氧的环境中在真空下退火。 真空优选保持在小于10-4毫巴的压力，含氧量小于约百万分之八十，退火温度超过400℃至少一小时，优选保持在约1100 -1200℃几个小时。 然后可以向支架施加厚度为299-300nm的氧化物表面层，例如氧化铱。

公开(公告)号：US20080147167A1

公开(公告)日：2008-06-19

申请号：US11952624

申请日：2007-12-07

Applicant: Torsten Scheuermann ,  Lutz Stehling

Inventor： Torsten Scheuermann ,  Lutz Stehling

IPC: A61F2/06 ,  A61L33/02

CPC classification number: A61L31/022 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/088 ,  A61L31/18

Abstract: In a process for producing a biocompatible stent, a tubular substrate of the stent adapted for diametric expansion has a layer of a noble metal oxide formed over at least the outer surface of greater diameter of the substrate, the substrate being composed of a metal or an alloy thereof that is non-noble or less-noble than the layer's noble metal. An interface region adapted to prevent corrosion and to provide a firm bond between the surface of the substrate and the noble metal oxide layer is established, at least in part, by forming the noble metal oxide layer with a progressively varying concentration of noble metal-to-oxide with depth of the layer such that a surface of pure noble metal and negligible oxide of the layer is in closest proximity to the surface of the substrate. In one embodiment of the process, the interface region is established by forming the surface of pure noble metal and negligible oxide thereof in direct contact with the metal or alloy of the substrate surface. In another, the interface region is established by first creating an oxide of the substrate metal or alloy thereof at the substrate surface, and then forming the noble metal oxide layer as above, but in contact with the substrate metal or alloy oxide. Alternatively, the noble metal oxide layer has no progressively varying concentration but simply overlies an oxide of the substrate metal or alloy.

Abstract translation: 在制造生物相容性支架的方法中，适用于直径膨胀的支架的管状基底具有至少在基底的较大直径的外表面上形成的贵金属氧化物层，该基底由金属或 它的合金是非贵重的或比贵金属低贵的贵金属。 至少部分地通过以逐渐变化的贵金属浓度形成贵金属氧化物层，从而建立适于防止腐蚀并提供衬底的表面与贵金属氧化物层之间牢固结合的界面区域 - 至少 氧化物，其层的深度使得纯贵金属的表面和该层的可忽略的氧化物最接近衬底的表面。 在该方法的一个实施方案中，通过形成纯金属的表面和与基底表面的金属或合金直接接触的可忽略的氧化物的表面来建立界面区域。 另一方面，通过首先在基板表面产生基板金属或其合金的氧化物，然后如上所述形成贵金属氧化物层，但与基板金属或合金氧化物接触来建立界面区域。 或者，贵金属氧化物层的浓度没有逐渐变化，而是简单地覆盖基板金属或合金的氧化物。

公开(公告)号：US07335229B2

公开(公告)日：2008-02-26

申请号：US10841113

申请日：2004-05-07

Applicant: Eckhard Alt ,  Torsten Scheuermann ,  Michael Kühling

Inventor： Eckhard Alt ,  Torsten Scheuermann ,  Michael Kühling

IPC: A61F2/06

CPC classification number: A61L31/18 ,  A61B5/055 ,  A61B5/411 ,  A61F2/88 ,  A61F2/91 ,  A61F2210/0076 ,  A61F2250/0043 ,  A61L31/022 ,  A61L31/082 ,  G01R33/285 ,  G01R33/34046 ,  G01R33/34053 ,  G01R33/34069 ,  G01R33/34076 ,  G01R33/34084

Abstract: A stent is adapted to be implanted in a duct of a human body to maintain an open lumen at the implant site, and to allow viewing body tissue and fluids by magnetic resonance imaging (MRI) energy applied external to the body. The stent constitutes a metal scaffold. An electrical circuit resonant at the resonance frequency of the MRI energy is fabricated integral with the scaffold structure of the stent to promote viewing body properties within the lumen of the stent.

Abstract translation: 支架适于植入人体的管道中，以在植入部位保持开放的腔，并且允许通过在身体外部施加的磁共振成像（MRI）能量观察体内组织和流体。 支架构成金属支架。 在MRI能量的共振频率下共振的电路与支架的支架结构一体制成，以促进支架内腔内的观察体特性。

公开(公告)号：US20060251794A1

公开(公告)日：2006-11-09

申请号：US11122583

申请日：2005-05-05

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61L33/00

CPC classification number: C03C8/00 ,  A61L31/082

Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a method includes diffusing a first element into a first portion of the medical device. The first element includes carbon, hydrogen, nitrogen, oxygen, or combinations thereof. The first portion includes a refractory material.

Abstract translation: 公开了诸如支架的医疗装置和制造装置的方法。 在一些实施例中，一种方法包括将第一元件扩散到医疗装置的第一部分中。 第一元素包括碳，氢，氮，氧或它们的组合。 第一部分包括耐火材料。

公开(公告)号：US08361139B2

公开(公告)日：2013-01-29

申请号：US12498829

申请日：2009-07-07

Applicant: Aiden Flanagan ,  Barry O'Brien ,  Torsten Scheuermann

Inventor： Aiden Flanagan ,  Barry O'Brien ,  Torsten Scheuermann

IPC: A61F2/06 ,  A61F2/00

CPC classification number: A61L31/088 ,  A61L31/16 ,  A61L2300/604 ,  A61L2300/624

Abstract: Medical devices having a plurality of nanoparticles disposed over a surface of the medical device. The nanoparticles have a core comprising a therapeutic agent and a shell surrounding the core, wherein the shell comprises a metal. A barrier layer is disposed over the nanoparticles. The barrier layer is water-permeable and comprises a metal that may be different from the metal used in the nanoparticle shells. In certain embodiments, the metal in the barrier layer undergoes galvanic corrosion. Also disclosed are medical device having a reservoir containing a therapeutic agent, with nanoparticles and a barrier layer being disposed over the reservoir; and medical devices having multiple barrier layers and multiple reservoirs containing therapeutic agents.

Abstract translation: 具有设置在医疗装置的表面上的多个纳米颗粒的医疗装置。 纳米颗粒具有包含治疗剂的核心和围绕核心的壳体，其中壳体包含金属。 阻挡层设置在纳米粒子上。 阻挡层是透水性的并且包含可以与纳米颗粒壳中使用的金属不同的金属。 在某些实施例中，阻挡层中的金属经历电偶腐蚀。 还公开了具有包含治疗剂的储存器的医疗装置，其中纳米颗粒和阻挡层设置在储存器上方; 以及具有多个阻隔层的医疗装置和含有治疗剂的多个储存器。

公开(公告)号：US08046048B2

公开(公告)日：2011-10-25

申请号：US12220819

申请日：2008-07-29

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61B5/05

CPC classification number: G01R33/286 ,  G01R33/3628

Abstract: Systems and methods for a resonator with an adjustable capacitance for a medical device. In one embodiment, a resonator system includes a resonator device with an LC resonator circuit that has an adjustable capacitance, an inductor coil in series with the adjustable capacitance, and an adjustable capacitance control that can control the adjustable capacitance to obtain different particular capacitance values. This embodiment also includes a medical device, positioned with the resonator device, so that at least a portion of the inductor coil surrounds a space that is surrounded by at least a portion of the medical device.

Abstract translation: 用于医疗设备具有可调电容的谐振器的系统和方法。 在一个实施例中，谐振器系统包括具有可调电容的LC谐振器电路的谐振器装置，与可调电容串联的电感线圈，以及可调节的电容控制，其可以控制可调电容以获得不同的特定电容值。 该实施例还包括与谐振器装置一起定位的医疗装置，使得电感线圈的至少一部分围绕由医疗装置的至少一部分包围的空间。