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公开(公告)号：US07294693B2
公开(公告)日：2007-11-13
申请号：US10142767
申请日：2002-05-10
申请人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC分类号： C07K14/435
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K14/82 , C07K16/18 , C07K17/00 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N5/06 , C12N9/00 , C12N9/001 , C12N9/1051 , C12N15/00 , C12N2799/026 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N33/5011 , G01N33/5014 , G01N33/502 , G01N33/5044 , G01N33/505 , G01N33/5061 , G01N33/53 , G01N33/574 , G01N33/57484 , G01N33/68 , G01N33/6845 , G01N2800/042 , Y10S530/828 , Y10S530/866
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07279552B2
公开(公告)日：2007-10-09
申请号：US10140021
申请日：2002-05-06
申请人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
发明人： Kevin P. Baker , Maureen Beresini , Laura DeForge , Luc Desnoyers , Ellen Filvaroff , Wei-Qiang Gao , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Steven Sherwood , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood , Zemin Zhang
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K14/82 , C07K16/18 , C07K17/00 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N5/06 , C12N9/00 , C12N9/001 , C12N9/1051 , C12N15/00 , C12N2799/026 , C12P21/02 , C12P21/06 , C12Q1/68 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5008 , G01N33/5011 , G01N33/5014 , G01N33/502 , G01N33/5044 , G01N33/505 , G01N33/5061 , G01N33/53 , G01N33/574 , G01N33/57484 , G01N33/68 , G01N33/6845 , G01N2800/042 , Y10S530/828 , Y10S530/866
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07619062B2
公开(公告)日：2009-11-17
申请号：US11080062
申请日：2005-03-14
申请人： Luc Desnoyers , Napoleone Ferrara , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , William I. Wood , Ellen Filvaroff
发明人： Luc Desnoyers , Napoleone Ferrara , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , William I. Wood , Ellen Filvaroff
IPC分类号： C07K14/435 , C07K19/00 , C07K14/515
CPC分类号： C07K14/47 , C07K14/50 , Y10S530/866
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those peptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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44.发明授权Antibodies to polypeptides encoded by a nucleic acid underexpressed in esophageal tumor 有权由在食管肿瘤中未表达的核酸编码的多肽的抗体公开(公告)号：US07288384B2
公开(公告)日：2007-10-30
申请号：US11102240
申请日：2005-04-08
申请人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
CPC分类号： G01N33/57484
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07230082B2
公开(公告)日：2007-06-12
申请号：US10063602
申请日：2002-05-03
申请人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC分类号： C07K16/00 , A61K39/395 , A61K39/00
CPC分类号： C07K14/47 , C07K14/705
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20080286821A1
公开(公告)日：2008-11-20
申请号：US11263278
申请日：2005-10-31
申请人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC分类号： C12Q1/02 , C12N15/11 , C12N15/00 , C12N5/06 , C12N1/20 , C12N1/14 , C12P21/04 , C07K14/00 , C07K16/18
CPC分类号： C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4703 , C07K14/52 , C07K14/54 , C07K14/705 , C07K14/70578 , C07K16/18 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N2799/026 , C12N2799/027
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20090136997A1
公开(公告)日：2009-05-28
申请号：US11929465
申请日：2007-10-30
申请人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
CPC分类号： C07K14/705 , C07K16/28 , C07K2317/24 , C07K2319/30 , C07K2319/40
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07189563B2
公开(公告)日：2007-03-13
申请号：US10063703
申请日：2002-05-08
申请人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
CPC分类号： C07K14/47 , A61K38/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/18 , C07K16/30 , C07K16/3023 , C07K16/3046 , C07K16/3053 , C07K16/40 , C07K2319/30 , C12N5/06 , Y10S530/866
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US07081520B2
公开(公告)日：2006-07-25
申请号：US10063639
申请日：2002-05-07
申请人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
发明人： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
CPC分类号： C07K14/47 , A61K38/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/18 , C07K16/30 , C07K16/3023 , C07K16/3046 , C07K16/3053 , C07K16/40 , C07K2319/30 , C12N5/06 , Y10S530/866
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07087738B2
公开(公告)日：2006-08-08
申请号：US09907942
申请日：2001-07-17
申请人： David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
发明人： David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
CPC分类号： C07K14/705 , C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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