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    Ex vivo modifiable medicament release-associations
    41.
    发明申请
    Ex vivo modifiable medicament release-associations 审中-公开
    离体可修饰的药物释放关联

    公开(公告)号：US20100068278A1

    公开(公告)日：2010-03-18

    申请号：US12387328

    申请日：2009-04-29

    申请人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

    发明人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

    IPC分类号： A61K9/14

    CPC分类号： G06F19/3456 ,  A61K9/06 ,  A61K9/127 ,  A61K9/4891 ,  A61K9/51

    摘要： Described embodiments include a final dosage form, an article of manufacture, and method. A described final dosage form includes a medicament, and a substance associated with the medicament in a first release-control state. In the first release-control state, the medicament has a first bioavailability to the animal. The substance is modifiable ex vivo by an exposure to a stimulus to associate with the medicament in a second release-control state, wherein the medicament has a second bioavailability to the animal. The final dosage form also includes another medicament, and another substance associated with the another medicament in another first release-control state. In the another first release-control state, the another medicament has another first bioavailability to the animal. The another substance is modifiable ex vivo by an exposure to another stimulus to associate with the another medicament in another second release-control state, wherein the another medicament has another second bioavailability.

    摘要翻译： 描述的实施方案包括最终剂型，制品和方法。 所描述的最终剂型包括药物和与第一释放 - 控制状态的药物相关的物质。 在第一释放控制状态下，药物对动物具有第一生物利用度。 该物质可通过暴露于第二释放 - 控制状态下的药物的刺激而离体修饰，其中所述药物对动物具有第二生物利用度。 最终剂型还包括另一种药物，以及另一种与另一种药物在另一种第一释放 - 控制状态相关的物质。 在另一个第一释放控制状态中，另一种药物对动物具有另一种第一生物利用度。 另一种物质可以通过暴露于另一种刺激而在另一种第二释放 - 控制状态下与另一种药物接触而离体修饰，其中另一种药物具有另一种第二生物利用度。

    Individualizable dosage form
    43.
    发明申请
    Individualizable dosage form 审中-公开
    可个性化的剂型

    公开(公告)号：US20100068235A1

    公开(公告)日：2010-03-18

    申请号：US12284015

    申请日：2008-09-16

    申请人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

    发明人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

    IPC分类号： A61K9/24 ,  A61K8/02

    CPC分类号： A61K9/28 ,  A61K9/0009 ,  G06F19/3462

    摘要： Provided embodiments include a final dosage form, an article of manufacture, and a method. A final dosage form for delivering a medicament to an animal is provided. The final dosage form includes an outer layer. The final dosage form also includes a release element configured in a first medicament-release state and modifiable to a second medicament-release state upon an ex vivo exposure to a stimulus. The final dosage form further includes a chamber at least substantially within the outer layer and configured to carry the medicament. The final dosage form further includes a containment element configured to retain the medicament within the final dosage form until the dosage form is administered to the animal. The final dosage form includes the medicament. The final dosage form may include an indicator element configured to indicate an exposure of the release element to the stimulus.

    摘要翻译： 所提供的实施方案包括最终剂型，制品和方法。 提供了用于将药物递送至动物的最终剂型。 最终剂型包括外层。 最终剂型还包括配置在第一药物释放状态中的释放元件，并且在体外暴露于刺激物时可修改为第二药物释放状态。 最终剂型还包括至少基本上在外层内并且构造成携带药物的腔室。 最终剂型还包括构造成将药物保持在最终剂型中直到将该剂型施用于动物的容纳元件。 最终剂型包括药物。 最终剂型可以包括指示元件，其被配置为指示释放元件暴露于刺激。

    Computational systems and methods for monitoring medication events including use of a camera and data comparison
    48.
    发明授权
    Computational systems and methods for monitoring medication events including use of a camera and data comparison 有权
    用于监测药物事件的计算系统和方法，包括使用相机和数据比较

    公开(公告)号：US09035777B2

    公开(公告)日：2015-05-19

    申请号：US13593917

    申请日：2012-08-24

    申请人： Mahalaxmi Gita Bangera ,  Roderick A. Hyde ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr.

    发明人： Mahalaxmi Gita Bangera ,  Roderick A. Hyde ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr.

    IPC分类号： G08B21/00 ,  G06F19/00 ,  A61B5/00

    CPC分类号： G06F19/3456 ,  A61B5/0022 ,  A61B5/0077 ,  A61B5/4833 ,  A61B5/4848 ,  A61B5/6898 ,  A61B2562/0204 ,  A61B2576/00 ,  G06F19/00 ,  G06F19/3418

    摘要： Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

    摘要翻译： 描述基于计算机的系统和计算机实现的方法来监测个体的药物事件。 基于计算机的系统包括用于监测与个体相关的药物事件的系统，包括：用于分析个体的第一药物事件标识符的数据的电路; 用于分析个人的至少一个属性的数据的电路; 用于在第一药物事件期间分析与药物有关的至少一个属性的数据的电路; 用于在第一药物事件期间分析视觉信息的至少一个特征的数据和与个体相关的非视觉信息的至少一个特征的电路; 用于分析与第一药物事件相关联的时间的接收数据的电路; 基于接收到的数据的分析来确定第一药物事件的依从性可能性的电路; 以及用于指示确定的依从性可能性的电路。

    Computational systems and methods for monitoring medication events
    49.
    发明授权
    Computational systems and methods for monitoring medication events 有权
    用于监测药物事件的计算系统和方法

    公开(公告)号：US08797167B2

    公开(公告)日：2014-08-05

    申请号：US13593840

    申请日：2012-08-24

    申请人： Mahalaxmi Gita Bangera ,  Roderick A. Hyde ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr.

    发明人： Mahalaxmi Gita Bangera ,  Roderick A. Hyde ,  Jordin T. Kare ,  Eric C. Leuthardt ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr.

    IPC分类号： G08B21/00

    CPC分类号： G06F19/3456 ,  A61J7/04 ,  A61J2200/30 ,  G06F19/00

    摘要： Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

    摘要翻译： 描述基于计算机的系统和计算机实现的方法来监测个体的药物事件。 基于计算机的系统包括用于监测与个体相关的药物事件的系统，包括：用于分析个体的第一药物事件标识符的数据的电路; 用于分析个人的至少一个属性的数据的电路; 用于在第一药物事件期间分析与药物有关的至少一个属性的数据的电路; 用于在第一药物事件期间分析视觉信息的至少一个特征的数据和与个体相关的非视觉信息的至少一个特征的电路; 用于分析与第一药物事件相关联的时间的接收数据的电路; 基于接收到的数据的分析来确定第一药物事件的依从性可能性的电路; 以及用于指示确定的依从性可能性的电路。