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公开(公告)号：US08920401B2
公开(公告)日：2014-12-30
申请号：US13460337
申请日：2012-04-30
申请人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
发明人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
CPC分类号： A61M5/31525 , A61B5/0002 , A61B5/14532 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B2560/0443 , A61M5/1723 , A61M11/00 , A61M15/0001 , A61M2005/1726 , A61M2205/18 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H20/17 , G16H40/63
摘要： Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.
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42.发明授权Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise 有权具有基本上不受非恒定噪声影响的信噪比的分析物传感器公开(公告)号：US08364229B2
公开(公告)日：2013-01-29
申请号：US11750907
申请日：2007-05-18
申请人： Peter C. Simpson , Robert Boock , James R. Petisce , Mark Brister , Monica A. Rixman , Kum Ming Woo , Lisa Nguyen , Seth R. Brunner , Arthur Chee , Melissa A. Nicholas , Matthew Wightlin , Jack Pryor , Dubravka Markovic
发明人： Peter C. Simpson , Robert Boock , James R. Petisce , Mark Brister , Monica A. Rixman , Kum Ming Woo , Lisa Nguyen , Seth R. Brunner , Arthur Chee , Melissa A. Nicholas , Matthew Wightlin , Jack Pryor , Dubravka Markovic
CPC分类号： A61B5/00 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B5/6848 , A61B5/7203
摘要： Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
摘要翻译： 提供涉及具有基本上不受非恒定噪声影响的信噪比的传感器的系统和方法用于主机中的连续分析物测量。 在一些实施例中，连续分析物测量系统被配置为完全，经皮，血管内或体外植入。
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公开(公告)号：US20120220979A1
公开(公告)日：2012-08-30
申请号：US13460219
申请日：2012-04-30
申请人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
发明人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
IPC分类号： A61M5/168
CPC分类号： A61M5/31525 , A61B5/0002 , A61B5/14532 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B2560/0443 , A61M5/1723 , A61M11/00 , A61M15/0001 , A61M2005/1726 , A61M2205/18 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H20/17 , G16H40/63
摘要： Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.
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公开(公告)号：US20120215201A1
公开(公告)日：2012-08-23
申请号：US13460337
申请日：2012-04-30
申请人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
发明人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
IPC分类号： A61M5/168
CPC分类号： A61M5/31525 , A61B5/0002 , A61B5/14532 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B2560/0443 , A61M5/1723 , A61M11/00 , A61M15/0001 , A61M2005/1726 , A61M2205/18 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H20/17 , G16H40/63
摘要： Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.
摘要翻译： 提供了用于集成包括接收器，药物输送装置和任选的单点葡萄糖监测器的连续葡萄糖传感器的系统和方法。 手动集成提供了用户（例如，患者或医生）手动选择数量，类型和/或递送时间的设备之间的物理关联。 设备的半自动化集成包括集成，其中集成组件之间的可操作连接有助于用户（例如患者或医生）在选择，输入，计算或验证葡萄糖值的药物递送量，类型或时间 例如，通过将数据发送到另一个组件，从而减少所需的用户输入量。 设备之间的自动集成包括集成，其中集成组件之间的可操作连接提供对系统的完全控制，而不需要用户交互。
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公开(公告)号：US07854745B2
公开(公告)日：2010-12-21
申请号：US12709344
申请日：2010-02-19
申请人： Mark C. Brister , Nelson Quintana , Kaushik A. Patel , Neil R. Drake , Antonio C. Llevares , Dubravka Markovic , Andrew P. Rasdal , Amy D. L. VandenBerg
发明人： Mark C. Brister , Nelson Quintana , Kaushik A. Patel , Neil R. Drake , Antonio C. Llevares , Dubravka Markovic , Andrew P. Rasdal , Amy D. L. VandenBerg
IPC分类号： A61M29/00
CPC分类号： A61F5/003 , A61B17/1204 , A61B17/12099 , A61B90/39 , A61B2090/3966 , A61F5/0036 , A61F5/0073 , A61F5/0083 , A61L31/088 , A61L31/10 , A61L2400/16 , A61L2420/02 , A61L2420/08 , A61M25/10185 , A61M25/1027 , A61M25/1029 , A61M31/002 , A61M2025/1031 , A61M2025/105 , Y10T156/1051
摘要： An implant configured for ingestion by a patient. After the implant has been swallowed by the patient and is disposed within the target location, e.g. the patient's stomach, an inflation subcomponent causes the implant to expand from a compact delivery state to an expanded, volume-occupying, deployed state. In the deployed state the implant creates a sensation of satiety in the patient stomach and thereby aids in limiting food intake and obesity. After a predetermined time a deflation subcomponent is actuated and the implant reduces in size so as to allow it to pass through the remainder of the patient's digestive track. The device may further incorporate tracking and visualization subcomponents, as well as pharmaceutical delivery subcomponents.
摘要翻译： 构造成用于由患者摄取的植入物。 在植入物被患者吞咽之后并且被放置在目标位置内，例如， 患者的胃，通气子部件导致植入物从紧凑的递送状态扩展到膨胀的体积占据部署状态。 在部署状态下，植入物在患者胃中产生饱腹感，从而有助于限制食物摄入和肥胖。 在预定时间之后，促使放气次级组件被移动并且植入物的尺寸减小，以便使其通过病人消化道的其余部分。 该装置还可以包括跟踪和可视化子组件以及药物递送子组件。
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公开(公告)号：US20100100116A1
公开(公告)日：2010-04-22
申请号：US12580044
申请日：2009-10-15
申请人： Mark C. Brister , Kaushik A. Patel , Andrew P. Rasdal , Nelson Quintana , Neil R. Drake , Antonio C. Llevares , Dubravka Markovic , Amy D.L. VandenBerg
发明人： Mark C. Brister , Kaushik A. Patel , Andrew P. Rasdal , Nelson Quintana , Neil R. Drake , Antonio C. Llevares , Dubravka Markovic , Amy D.L. VandenBerg
CPC分类号： A61F5/003 , A61B17/1204 , A61B17/12099 , A61B90/39 , A61B2090/3966 , A61F5/0036 , A61F5/0073 , A61F5/0083 , A61L31/088 , A61L31/10 , A61L2400/16 , A61L2420/02 , A61L2420/08 , A61M25/10185 , A61M25/1027 , A61M25/1029 , A61M31/002 , A61M2025/1031 , A61M2025/105 , Y10T156/1051
摘要： Intragastric volume-occupying devices and methods for treating obesity are provided. The devices, which are inflated by carbon dioxide, include an aluminum or silicon oxide barrier layer providing carbon dioxide retention and an alkylene vinyl alcohol polymer layer providing structural integrity in vivo.
摘要翻译： 提供用于治疗肥胖的胃内体积占用装置和方法。 由二氧化碳充气的装置包括提供二氧化碳保留的铝或氧化硅阻挡层和在体内提供结构完整性的亚烷基乙烯醇聚合物层。
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公开(公告)号：US07591801B2
公开(公告)日：2009-09-22
申请号：US10789359
申请日：2004-02-26
申请人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
发明人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv U. Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
IPC分类号： A61M37/00
CPC分类号： A61M5/31525 , A61B5/0002 , A61B5/14532 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B2560/0443 , A61M5/1723 , A61M11/00 , A61M15/0001 , A61M2005/1726 , A61M2205/18 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H20/17 , G16H40/63
摘要： Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.
摘要翻译： 提供了用于集成包括接收器，药物输送装置和任选的单点葡萄糖监测器的连续葡萄糖传感器的系统和方法。 手动集成提供了用户（例如，患者或医生）手动选择数量，类型和/或递送时间的设备之间的物理关联。 设备的半自动化集成包括集成，其中集成组件之间的可操作连接有助于用户（例如患者或医生）在选择，输入，计算或验证葡萄糖值的药物递送量，类型或时间 例如，通过将数据发送到另一个组件，从而减少所需的用户输入量。 设备之间的自动集成包括集成，其中集成组件之间的可操作连接提供对系统的完全控制，而不需要用户交互。
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