公开(公告)号：USD656230S1

公开(公告)日：2012-03-20

申请号：US29396048

申请日：2011-06-24

Applicant: Alexander Robinson ,  Joseph Taylor ,  Mark Williams

Designer： Alexander Robinson ,  Joseph Taylor ,  Mark Williams

公开(公告)号：US08073791B2

公开(公告)日：2011-12-06

申请号：US12148310

申请日：2008-04-18

Applicant: Mark Williams ,  Alan Williams

Inventor： Mark Williams ,  Alan Williams

IPC: G06F15/18 ,  G06N3/00 ,  G06N3/12 ,  G01V3/00 ,  G01V7/00

CPC classification number: G06N3/12 ,  G06N3/126

Abstract: A method is disclosed that generates design profiles and a surface therefrom that promote water drainage from soil in an area of interest. Topographical data describing an initial surface of the area of interest are used to form initial profiles. The method generates the design profiles using the initial profiles and desired design parameters such as minimum slope, maximum slope, optimal slope, maximum depth, optimal depth, starting elevation, ending elevation, rules of curvature, and rules of earth balancing. The method generates design surface profiles so that the cut volumes and fill volumes of the soil are at or near balance as much as possible from the available soil in the area of interest.

Abstract translation: 公开了一种从感兴趣区域的土壤产生排水的设计简档和表面的方法。 描述描述感兴趣区域的初始表面的地形数据用于形成初始轮廓。 该方法使用初始轮廓和期望的设计参数（如最小坡度，最大坡度，最优坡度，最大深度，最佳深度，起始仰角，结束高程，曲率规则和土方平衡规则）生成设计轮廓。 该方法产生设计表面轮廓，使得土壤的切割体积和填充体积尽可能距离感兴趣区域中的可用土壤处于或接近平衡。

公开(公告)号：US20110006076A1

公开(公告)日：2011-01-13

申请号：US12831263

申请日：2010-07-07

Applicant: Mark Williams

Inventor： Mark Williams

IPC: B65D35/28

CPC classification number: B65D75/5883 ,  B05B11/02 ,  B05B11/048 ,  B05C17/00583 ,  B05C17/0123 ,  B05C17/0136 ,  B05C17/0146 ,  B05C17/015

Abstract: A system for dispensing sprayable material such as paint and other liquefied products. The system includes a dispenser designed to accept a flexible, crushable, container filled with sprayable material and having a valve and spray tip at one end. The container is placed into a slot in the dispenser with the valve on the container secured in the housing of the dispenser. In operation, a plunger that runs lengthwise within the housing of the dispenser exerts force on the bottom of the container crushing it as it is emptied and forcing the sprayable material out through the valve and spray tip.

Abstract translation: 用于分配可喷涂材料如油漆和其它液化产品的系统。 该系统包括一个分配器，设计成接收一个充满可喷涂材料的柔性，可粉碎的容器，并在一端具有一个阀和喷嘴。 将容器放置在分配器中的狭槽中，容器上的阀固定在分配器的壳体中。 在操作中，在分配器的壳体内纵向延伸的柱塞在容器的底部施加力，当其被排空时将其压碎并迫使可喷涂材料通过阀门和喷嘴。

公开(公告)号：US20100008899A1

公开(公告)日：2010-01-14

申请号：US12374872

申请日：2007-07-26

Applicant: Mark Williams

Inventor： Mark Williams

IPC: A61K38/48 ,  C12Q1/37 ,  A61P3/00

CPC classification number: A61K38/4853 ,  A61K38/26 ,  A61K38/556 ,  A61K45/06 ,  C12Q1/37 ,  C12Y304/21035 ,  G01N2333/96455 ,  G01N2800/042 ,  A61K2300/00

Abstract: The invention relates to pharmaceutical compositions comprising tissue kallikrem (TK), and optionally a diabetes drug, a method of screening for a metabolic disorder by determining the concentration of TK and insulin in a biological sample from a test subject, a method of screening for a therapeutic agent for the treatment or prevention of a metabolic disorder, and a method for treating or preventing a metabolic disorder using a pharmaceutical composition comprising TK.

Abstract translation: 本发明涉及包含组织激肽（TK）和任选的糖尿病药物的药物组合物，通过测定来自测试对象的生物样品中的TK和胰岛素的浓度来筛选代谢紊乱的方法，筛选 用于治疗或预防代谢紊乱的治疗剂，以及使用包含TK的药物组合物治疗或预防代谢紊乱的方法。

公开(公告)号：US20090324701A1

公开(公告)日：2009-12-31

申请号：US12161577

申请日：2007-01-19

Applicant: Mark Williams

Inventor： Mark Williams

IPC: A61K31/27 ,  A61K38/28 ,  A61K31/426 ,  A61K9/127 ,  A61P3/10

CPC classification number: A61K31/27 ,  A61K31/198 ,  A61K31/385 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention provides pharmaceutical compositions comprising (S)-bethanechol or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable carrier and optionally at least one diabetes drug. The use of said composition in the treatment of insulin resistance, type 2 diabetes, impaired glucose tolerance and related disorders is also provided. The invention also provides for a kit comprising the pharmaceutical compositions and instructions for its use.

Abstract translation: 本发明提供包含（S） - 乙酰胆碱或其药学上可接受的盐，药学上可接受的载体和任选的至少一种糖尿病药物的药物组合物。 还提供了所述组合物在治疗胰岛素抵抗，2型糖尿病，葡萄糖耐量异常和相关病症中的用途。 本发明还提供了包含药物组合物和其使用说明书的试剂盒。

公开(公告)号：US20090298137A1

公开(公告)日：2009-12-03

申请号：US12091948

申请日：2006-10-23

Applicant: Oskar Zelder ,  Andreas Herold ,  Corinna Klopprogge ,  Hartwig Schröder ,  Stefan Haefner ,  Elmar Heinzle ,  Christoph Wittmann ,  Jens Kroemer ,  Janice G. Pero ,  R. Rogers Yocum ,  Thomas A. Patterson ,  Mark Williams ,  Theron Herman

Inventor： Oskar Zelder ,  Andreas Herold ,  Corinna Klopprogge ,  Hartwig Schröder ,  Stefan Haefner ,  Elmar Heinzle ,  Christoph Wittmann ,  Jens Kroemer ,  Janice G. Pero ,  R. Rogers Yocum ,  Thomas A. Patterson ,  Mark Williams ,  Theron Herman

IPC: C12P13/12 ,  C12N1/21

CPC classification number: C12P13/12 ,  A23K10/16 ,  A23K20/142 ,  A23K40/10 ,  C12N15/52

Abstract: The present invention relates to microorganisms and processes for the efficient preparation of L-amino acids such as L-methionine. In particular, the present invention relates to microorganisms and processes in which the formation and/or accumulation of homolanthionine in the methionine pathway is reduced and/or prevented.

Abstract translation: 本发明涉及用于有效制备L-氨基酸如L-甲硫氨酸的微生物和方法。 特别地，本发明涉及微生物和其中甲硫氨酸途径中高山ion素的形成和/或积累减少和/或预防的方法。

公开(公告)号：US07530040B1

公开(公告)日：2009-05-05

申请号：US11383658

申请日：2006-05-16

Applicant: Graham Balsdon ,  Jeremy Birch ,  Mark Williams ,  Mark Waller ,  Tim Parker ,  Fumiaki Sato

Inventor： Graham Balsdon ,  Jeremy Birch ,  Mark Williams ,  Mark Waller ,  Tim Parker ,  Fumiaki Sato

IPC: G06F17/50

CPC classification number: G06F17/5077

Abstract: A technique will automatically route interconnect of an integrated circuit while taking into consideration current density rules. In an implementation, the technique uses a shape-based approach where a grid is not used. Based on data input including current density and a frequency of each net, the technique will determine the current requirements for each net. In an implementation, the technique forms a Steiner tree for a net, and routs using the Steiner tree. The technique widens nets having greater current requirements; adjacent wiring may be pushed aside to create sufficient space for wider nets.

Abstract translation: 一种技术将自动路由集成电路的互连，同时考虑电流密度规则。 在实现中，该技术使用基于形状的方法，其中不使用网格。 基于数据输入，包括电流密度和每个网络的频率，该技术将确定每个网络的当前要求。 在实现中，该技术为网络形成Steiner树，并使用Steiner树进行路由。 该技术扩大了具有更大电流要求的网络; 可以将相邻的布线推到一边以产生用于更宽的网的足够的空间。

公开(公告)号：US20080148255A1

公开(公告)日：2008-06-19

申请号：US11967362

申请日：2007-12-31

Applicant: Puthukode G. Ramachandran ,  John C. Sanchez ,  Lorin Evan Ullmann ,  Mark Williams

Inventor： Puthukode G. Ramachandran ,  John C. Sanchez ,  Lorin Evan Ullmann ,  Mark Williams

IPC: G06F9/445

CPC classification number: G06F8/61

Abstract: A method, apparatus, and computer instructions for installing software in a network data processing system. An event is detected in the network data processing system indicating that a software module is to be installed in a set of data processing systems in the network data processing system. A configuration of each data processing system in the set of data processing systems is discovered, and a set of instructions is created using a knowledge base of prior installations. The set of instructions is tailored for each data processing system in the set of data processing systems based on the configuration for the each data processing system in the set of data processing systems. The set of instructions for the software module to be installed is sent to the set of data processing systems.

Abstract translation: 一种用于在网络数据处理系统中安装软件的方法，装置和计算机指令。 在网络数据处理系统中检测到事件，其指示将软件模块安装在网络数据处理系统中的一组数据处理系统中。 发现数据处理系统集中的每个数据处理系统的配置，并且使用现有安装的知识库创建一组指令。 基于数据处理系统中的每个数据处理系统的配置，该组指令针对数据处理系统集合中的每个数据处理系统而定制。 将要安装的软件模块的指令集发送到一组数据处理系统。

公开(公告)号：US20080064599A1

公开(公告)日：2008-03-13

申请号：US11880955

申请日：2007-07-24

Applicant: Robert Houtz ,  Lynnette Dirk ,  Mark Williams

Inventor： Robert Houtz ,  Lynnette Dirk ,  Mark Williams

IPC: A01N25/00 ,  C12N15/82

CPC classification number: C12N15/8274 ,  A01N43/36 ,  A01N61/00 ,  C07K14/415 ,  C12N9/14 ,  C12N9/80

Abstract: The invention relates to a method of identifying herbicides and to the use of inhibitors of plant peptide deformylase as broad spectrum herbicides.

Abstract translation: 本发明涉及一种鉴定除草剂的方法以及植物肽去甲酰化酶抑制剂作为广谱除草剂的用途。

公开(公告)号：US20080050824A1

公开(公告)日：2008-02-28

申请号：US11926180

申请日：2007-10-29

Applicant: Thao Dam ,  Anthony Guida ,  Christine Hazel ,  Bailin Li ,  Mark Williams

Inventor： Thao Dam ,  Anthony Guida ,  Christine Hazel ,  Bailin Li ,  Mark Williams

IPC: A01H5/00 ,  C07H21/04 ,  C12N15/00

CPC classification number: C12N15/8278 ,  C12N15/8274

Abstract: This invention relates to polynucleotide sequences encoding a gene that can confer resistance to at least one herbicide. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resistance to at least one herbicide, and methods of making said plants and seeds. The invention further presents sequences that can be used as molecular markers that in turn can be used to identify the region of interest in corn lines resulting from new crosses and to quickly and efficiently select the best lines for breeding strategies by avoiding sensitive lines.