公开(公告)号：US20180311040A1

公开(公告)日：2018-11-01

申请号：US15964455

申请日：2018-04-27

Applicant: Medtronic, Inc.

Inventor： Michael Gloss ,  Patrick Griffin ,  Paul Rothstein ,  Jeffrey Sandstrom ,  Brendan Vaughan ,  Stephen Montgomery ,  Alan McGuinn

IPC: A61F2/24 ,  A61F2/962

Abstract: The disclosure relates to transcatheter stented prosthesis delivery devices including transition elements that route, constrain, support and reduce damage to tension member wear as tension in the tension members is varied to adjust the compression of a stented prosthesis loaded onto the delivery device. Various disclosed tension elements include inserts, edge treatments and guides proximate a distal portion of the delivery device upon which the stented prosthesis is loaded. In some embodiments, the transition feature is positioned proximate a location where at least one tension member transitions from a first orientation that is not parallel to the distal portion to a second orientation that is generally parallel to the distal portion. Further embodiments disclose configurations and methods of selectively locking and unlocking a longitudinal and/or rotational position of the stent frame with respect to the distal portion of the delivery device.

公开(公告)号：US20180280171A1

公开(公告)日：2018-10-04

申请号：US15938576

申请日：2018-03-28

Applicant: Medtronic, Inc.

Inventor： Michael Gloss ,  Patrick Griffin ,  Jeffrey Sandstrom ,  David O'Toole ,  Rishi Manda ,  Niall Duffy

IPC: A61F2/95 ,  A61F2/24

Abstract: The present disclosure relates to delivery devices for transcatheter stented prosthesis loading, delivery and implantation. The delivery devices provide a loaded delivery state in which the stented prosthesis is loaded and compressed over the delivery device. The compression of the stented prosthesis can be adjusted with one or more elongate tension members, which extend around the stented prosthesis and proximately to an actuation and release assembly that can be provided as part of a handle assembly. The delivery device can be manipulated to adjust tension in the tension members to permit the stented prosthesis to compress, self-expand, and ultimately release from the shaft assembly. In some embodiments, the tension in one or more tension members is adjusted with one or more actuation and release assemblies.

公开(公告)号：US20170224480A1

公开(公告)日：2017-08-10

申请号：US15494923

申请日：2017-04-24

Applicant: Medtronic, Inc.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US09675451B2

公开(公告)日：2017-06-13

申请号：US14242347

申请日：2014-04-01

Applicant: Medtronic, Inc.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0069

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US08986375B2

公开(公告)日：2015-03-24

申请号：US13795066

申请日：2013-03-12

Applicant: Medtronic, Inc.

Inventor： Kshitija Garde ,  Philip Haarstad ,  Igor Kovalsky ,  Stephen Nash ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Jeffrey Sandstrom ,  Padraig Savage ,  William Steinberg

IPC: A61F2/24

CPC classification number: A61F2/2445 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2250/0069

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.

Abstract translation: 经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。 每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。 每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。 在压缩构型中，每个支柱远离支架远端延伸。 在展开的构造中，每个支柱向近端延伸远离支架的远端。 在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。 在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

公开(公告)号：US20140243879A1

公开(公告)日：2014-08-28

申请号：US13777131

申请日：2013-02-26

Applicant: MEDTRONIC, INC.

Inventor： Paul Rothstein ,  Jason Quill ,  Dean Christiansen ,  Elizabeth Schotzko ,  Joel Racchini ,  Jeffrey Sandstrom ,  Cynthia Clague

IPC: A61F2/01

CPC classification number: A61F2/013 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2210/009

Abstract: An embolic protection device includes a first filter configured to be disposed in a first vessel and a second filter configured to be disposed in a second vessel. A first tether extends from a proximal end of the first filter and a first magnet is coupled to the first tether. A second tether extends from a proximal end of the second filter and a second magnet is coupled to the second tether. The device is configured such that when the first filter is disposed in the first vessel and the second filter is disposed in the second vessel, the first magnet and the second magnet are magnetically coupled to each other to couple the first tether to the second tether.

Abstract translation: 栓塞保护装置包括被配置为设置在第一容器中的第一过滤器和被配置为设置在第二容器中的第二过滤器。 第一系绳从第一过滤器的近端延伸并且第一磁体联接到第一系绳。 第二系绳从第二过滤器的近端延伸并且第二磁体联接到第二系绳。 该装置被构造成使得当第一过滤器设置在第一容器中并且第二过滤器设置在第二容器中时，第一磁体和第二磁体彼此磁耦合以将第一系绳耦合到第二系绳。

公开(公告)号：US20140222142A1

公开(公告)日：2014-08-07

申请号：US14175100

申请日：2014-02-07

Applicant: Medtronic, Inc.

Inventor： Igor Kovalsky ,  Cathleen Bergin ,  Marian Creaven ,  Joshua Dwork ,  Kshitija Garde ,  Daniel Glozman ,  Ilia Hariton ,  Pham Lo ,  Jason Quill ,  Jeffrey Sandstrom ,  Padraig Savage ,  Michael Schendel ,  Elizabeth Schotzko ,  Yossi Tuval ,  Nadav Yellin

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0036 ,  A61F2250/0071

Abstract: Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.

Abstract translation: 公开了包括具有流入部分，阀保持管状或中心部分和一对支撑臂的框架或支撑结构的心脏瓣膜假体。 流入部分从阀保持管状部分的第一端径向延伸，并且一对支撑臂沿圆周间隔开并且从阀保持管状部分的相对的第二端径向延伸。

公开(公告)号：US20230397986A1

公开(公告)日：2023-12-14

申请号：US18456548

申请日：2023-08-28

Applicant: MEDTRONIC, INC.

Inventor： Paul Rothstein ,  Jeffrey Sandstrom ,  Geoffrey Orth

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2002/826

Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.

公开(公告)号：US20230139876A1

公开(公告)日：2023-05-04

申请号：US17957943

申请日：2022-09-30

Applicant: Medtronic, Inc.

Inventor： Jason Bowe ,  Matthew Genovese ,  Victoria Ung ,  Jeffrey Sandstrom ,  Matthew Ziebol ,  Steven Claessens ,  Radhika Bhargav ,  Alkindi Kibria ,  Salvador O. Avelar ,  Brian Castelli

IPC: A61F2/24

Abstract: An assembly including a transcatheter valve prosthesis and a leaflet folding accessory configured for use when compressing the transcatheter valve prosthesis into the crimped configuration. The transcatheter valve prosthesis includes a frame and a prosthetic valve component including at least one leaflet disposed within and secured to the frame. The leaflet folding accessory includes a plurality of guide fingers. A leaflet contact portion of each guide finger is configured to be disposed radially within the frame and contact an inner surface of a leaflet of the at least one leaflet. During crimping of the transcatheter valve prosthesis, the plurality of guide fingers remain disposed radially within the frame such that the at least one leaflet preferentially folds around the plurality of guide fingers.

公开(公告)号：US10813740B2

公开(公告)日：2020-10-27

申请号：US16011057

申请日：2018-06-18

Applicant: MEDTRONIC, INC.

Inventor： Elizabeth Schotzko ,  Joel Racchini ,  Jeffrey Sandstrom

IPC: A61F2/01

Abstract: An embolic protection device includes a shaft, a first magnet fixedly coupled to a distal portion of the shaft, a second magnet slidingly coupled to the shaft proximal to the first magnet, and a filter including a distal portion coupled to the first magnet and a proximal portion coupled to the second magnet. The first and second magnets are magnetically attracted to each other such that in a radially compressed configuration of the filter, the second magnet is spaced from the first magnet a first distance, and in a radially expanded configuration of the filter, the second magnet slides towards the first magnet such that the second magnet is spaced a second distance from the first magnet, wherein the second distance is smaller than the first distance.