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公开(公告)号：US20120123439A1
公开(公告)日：2012-05-17
申请号：US12946645
申请日：2010-11-15
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F9/0008
摘要： The invention generally relates to devices for deploying an intraocular shunt within an eye. In certain embodiments, devices of the invention include a housing, a deployment mechanism at least partially disposed within the housing, and a hollow shaft coupled to the deployment mechanism, in which the shaft is configured to hold an intraocular shunt, and in which rotation of the deployment mechanism results in deployment of the shunt.
摘要翻译： 本发明一般涉及用于在眼睛内部署眼内分流装置。 在某些实施例中，本发明的装置包括壳体，至少部分地设置在壳体内的展开机构，以及联接到展开机构的中空轴，其中轴构造成保持眼内分流，并且其中旋转 部署机制导致了分流器的部署。
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公开(公告)号：US20120123438A1
公开(公告)日：2012-05-17
申请号：US12946572
申请日：2010-11-15
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F2/95 , A61F2/966 , A61F9/00 , A61F9/0017 , A61F9/00709 , A61F9/00736 , A61F9/008
摘要： The present invention generally relates to the reduction of intraocular pressure, and in particular, to methods for treating glaucoma by insertion of an intraocular shunt in the eye such that it forms a drainage pathway between the anterior chamber and the intra-Tenon's space.
摘要翻译： 本发明一般涉及眼内压的降低，特别是涉及通过在眼睛中插入眼内分流来治疗青光眼的方法，使得其在前房和内耳间的空间之间形成排水通路。
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公开(公告)号：US20120123317A1
公开(公告)日：2012-05-17
申请号：US12946556
申请日：2010-11-15
IPC分类号： A61M5/00
CPC分类号： A61F9/00781
摘要： The present invention generally relates to the reduction of intraocular pressure, and in particular, to improved methods for implanting an intraocular shunt in the eye to treat glaucoma. The methods provide for implantation of an intraocular shunt while minimizing the risk of severe eye trauma due to the interaction between the deployment device and the surrounding eye tissue.
摘要翻译： 本发明一般涉及眼内压的降低，特别是涉及用于将眼内分流植入眼睛以治疗青光眼的改进方法。 这些方法提供了眼内分流植入，同时最小化由于展开装置和周围眼睛组织之间的相互作用引起的严重眼睛创伤的风险。
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公开(公告)号：US20120089134A1
公开(公告)日：2012-04-12
申请号：US12902105
申请日：2010-10-11
IPC分类号： A61B18/20
CPC分类号： A61F9/00825 , A61F2009/0087 , A61F2009/00889
摘要： Method, apparatus and systems for laser surgery as part of cataract surgery. The implementation thereof includes: A means to perform an anterior or posterior capsulorhexis using a rapid fire sequence of photodisruptive laser pulses, placed to open the capsule for cataract surgery. The system and methods provides the means to target and direct the laser pulse sequence into the desired region of the eye without the need of a patient interface or other contact with the eye.
摘要翻译： 用于激光手术的方法，装置和系统作为白内障手术的一部分。 其实现包括：使用放置以打开用于白内障手术的胶囊的光致破坏性激光脉冲的快速火焰序列来执行前部或后部撕囊术的手段。 该系统和方法提供了将激光脉冲序列靶向并定向到眼睛期望区域的手段，而不需要患者接口或与眼睛的其它接触。
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公开(公告)号：US08014052B2
公开(公告)日：2011-09-06
申请号：US12787811
申请日：2010-05-26
IPC分类号： G02B26/02
CPC分类号： G02B26/04 , G02B6/266 , G02B6/3552 , G02B6/3568 , Y10S359/90
摘要： Generally speaking, the output brightness of an illuminator is varied by chopping an output light beam such that the beam is alternately interrupted and unhindered. An interrupter can be rapidly moved into and out of the transmission path of a light beam. The brightness of the light beam received at a site will be attenuated based on the amount of time per cycle the light beam remains obstructed versus unhindered.
摘要翻译： 一般来说，通过切断输出光束来改变照明器的输出亮度，使得光束被交替地中断和不受阻碍。 断路器可以快速地移入和移出光束的传输路径。 基于每个周期的时间量，在一个地点接收的光束的亮度将被衰减，而不受阻碍。
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公开(公告)号：US20110106068A1
公开(公告)日：2011-05-05
申请号：US12836961
申请日：2010-07-15
申请人： Christopher Horvath , Mark Buczek , T. Scott Rowe
发明人： Christopher Horvath , Mark Buczek , T. Scott Rowe
CPC分类号： G05G1/38 , A61B17/00 , A61B34/20 , A61B2017/00119 , A61B2017/00194 , A61B2017/00199 , A61B2017/00221 , A61B2017/00973 , A61C1/0023 , H01H21/26 , H01H2239/076 , H01H2300/014 , H01H2300/03 , Y02B70/3241 , Y04S20/227 , Y10T74/2054 , Y10T74/20888 , Y10T307/747
摘要： The present invention provides a surgical footswitch that includes a base, a pedal, an encoder assembly, a wireless interface, and an internal power generator. The pedal mounts upon the base and pivots. The encoder assembly couples to the pedal. As the pedal pivots, the encoder assembly translates the mechanical signal of the pedal into a control signal based on the pedals position and/or orientation. The wireless interface couples the encoder assembly to receive the control signal. The wireless interface also couples the surgical footswitch to a surgical console operable to control and direct surgical equipment. The wireless interface passes the control signal from the encoder to the surgical console, which then directs the surgical equipment based on the control signal. This wireless interface eliminates the tangle of wires or tethers, which may be a hazard in the surgical theater. The internal power generator translates footswitch movement into stored energy to eliminate potential failures of the footswitch during a procedure and overcome the need to replace batteries within the footswitch.
摘要翻译： 本发明提供了一种手术脚踏开关，其包括底座，踏板，编码器组件，无线接口和内部发电机。 踏板安装在底座上并枢转。 编码器组件耦合到踏板。 当踏板枢转时，编码器组件基于踏板位置和/或方向将踏板的机械信号转换为控制信号。 无线接口耦合编码器组件以接收控制信号。 无线接口还将手术脚踏开关连接到可操作以控制和引导手术设备的外科手术台。 无线接口将控制信号从编码器传递到外科控制台，然后控制信号根据控制信号引导外科设备。 这种无线接口消除了电线或系绳的缠结，这可能是外科手术室的危险。 内部发电机将脚踏开关转换为储存的能量，以消除脚踏开关在程序期间的潜在故障，并克服了更换脚踏开关内的电池的需要。
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公开(公告)号：US20100232002A1
公开(公告)日：2010-09-16
申请号：US12787811
申请日：2010-05-26
IPC分类号： G02B26/04
CPC分类号： G02B26/04 , G02B6/266 , G02B6/3552 , G02B6/3568 , Y10S359/90
摘要： Generally speaking, the output brightness of an illuminator is varied by chopping an output light beam such that the beam is alternately interrupted and unhindered. An interrupter can be rapidly moved into and out of the transmission path of a light beam. The brightness of the light beam received at a site will be attenuated based on the amount of time per cycle the light beam remains obstructed versus unhindered.
摘要翻译： 一般来说，通过切断输出光束来改变照明器的输出亮度，使得光束被交替地中断和不受阻碍。 断路器可以快速地移入和移出光束的传输路径。 基于每个周期的时间量，在一个地点接收的光束的亮度将被衰减，而不受阻碍。
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公开(公告)号：US20100145320A1
公开(公告)日：2010-06-10
申请号：US12634150
申请日：2009-12-09
CPC分类号： A61F9/008 , A61F2009/00872
摘要： Embodiments of the present invention provide a laser surgical system with a basic set of functionality which is remotely controllable to implement an advanced set of functionality. According to one embodiment of the present invention, a basic laser surgical system may be coupled to an advanced control unit such that the basic laser surgical system may be controllable by the advanced control unit to implement a broader set of functionality. By moving less frequently used functionality to an advanced unit, the basic unit may be streamlined with regards to both cost and size, and the learning curve required to utilize the basic unit may be reduced relative to a more feature-ladened unit, allowing the basic unit to be utilized in myriad situations or procedures where an “all-in-one” unit would be less than desirable.
摘要翻译： 本发明的实施例提供具有基本功能集的激光手术系统，其可远程控制以实现高级功能集。 根据本发明的一个实施例，基本的激光手术系统可以耦合到高级控制单元，使得基本的激光手术系统可以由高级控制单元控制，以实现更广泛的功能。 通过将较少使用的功能移动到高级单元，可以在成本和尺寸方面简化基本单元，并且可以相对于更特征加载的单元减少使用基本单元所需的学习曲线，从而允许基本单元 单位将用于无数情况或程序中，“一体化”单位不太可取。
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公开(公告)号：US07619171B2
公开(公告)日：2009-11-17
申请号：US11474668
申请日：2006-06-26
申请人： Christopher Horvath , Bruno Dacquay
发明人： Christopher Horvath , Bruno Dacquay
IPC分类号： H01H3/14
CPC分类号： A61F9/008 , A61B2017/00367 , A61B2017/00973
摘要： A multifunction surgical footswitch is disclosed, one embodiment of the surgical footswitch comprising: a base assembly, wherein the base assembly comprises a shroud and a heel plate; a stand-by/ready switch attached to the base assembly and operable to provide a stand-by/ready control signal to switch a laser between a stand-by and a ready state; and a firing switch attached to the base assembly and operable to provide a firing control signal to fire the laser. The surgical footswitch can further comprise an interface communicatively coupled to the firing switch and the stand-by/ready switch and operable to communicate the firing and the stand-by/ready control signals to the laser.
摘要翻译： 公开了一种多功能手术脚踏开关，所述外科脚踏开关的一个实施例包括：基座组件，其中所述基座组件包括护罩和跟部板; 附接到基座组件的待机/就绪开关，其可操作以提供备用/准备好的控制信号，以在待机状态和就绪状态之间切换激光; 以及安装在基座组件上并可操作以提供点火控制信号来触发激光器的点火开关。 外科脚踏开关还可以包括通信地联接到点火开关和待机/就绪开关的接口，并且可操作以将击发和备用/就绪控制信号传送到激光器。
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公开(公告)号：US07442775B2
公开(公告)日：2008-10-28
申请号：US10766610
申请日：2004-01-27
申请人： Gregory J. LaRosa , Christopher Horvath , Walter Newman , S. Tarran Jones , Siobhan H. O'Brien , Theresa O'Keefe
发明人： Gregory J. LaRosa , Christopher Horvath , Walter Newman , S. Tarran Jones , Siobhan H. O'Brien , Theresa O'Keefe
CPC分类号： C07K16/2866 , A61K2039/505 , C07K14/7158 , C07K2317/24 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2319/00
摘要： The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
摘要翻译： 本发明涉及与哺乳动物（例如人）CC趋化因子受体2（CCR2）或受体的一部分结合并阻断配体与受体的结合的人源化抗体或其功能片段。 本发明还涉及抑制携带哺乳动物CCR2的细胞与其配体的相互作用的方法，以及在治疗，预防和诊断方法中使用抗体和片段。
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