公开(公告)号：US5723969A

公开(公告)日：1998-03-03

申请号：US660259

申请日：1996-06-07

申请人： Stephen T. Archer ,  Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Stephen T. Archer ,  Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： H02J7/00 ,  H01M10/44 ,  H01M10/46

CPC分类号： H02J7/0093

摘要： A high voltage charger operates in a three-phase cycle. In a first phase, the high voltage charger operates at a fixed frequency. In a second phase, the high voltage charger operates at a variable frequency designed to draw a substantially constant average current from a power source. In the third phase, the high voltage charger returns to fixed frequency operation. The variable frequency is the reciprocal of the sum of an on-time and an off-time of the switch. In one embodiment, the on-time is provided by the time required for the switch to reach a predetermined maximum and the off-time is provided by the time over which a magnetic field in a transformer collapses.

摘要翻译： 高压充电器以三相循环工作。 在第一阶段，高压充电器以固定频率工作。 在第二阶段中，高压充电器以设计成从电源绘制基本恒定的平均电流的可变频率工作。 在第三阶段，高压充电器返回固定频率运行。 可变频率是开关的导通时间和关断时间之和的倒数。 在一个实施例中，导通时间由开关达到预定最大值所需的时间提供，并且关断时间由变压器中的磁场塌陷的时间提供。

公开(公告)号：US5456706A

公开(公告)日：1995-10-10

申请号：US177293

申请日：1994-01-04

申请人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

发明人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

IPC分类号： A61N1/05 ,  A61N1/39

CPC分类号： A61N1/0563 ,  A61N1/3956

摘要： A lead for use with an implantable cardioverter/defibrillator system is disclosed. In the preferred embodiment, the lead combines a right ventricular endocardial electrode, a superior vena cava electrode and one or more atrial sensing electrodes on a single catheter lead. The distal end of the lead is transvenously implanted, typically through an incision in the cephalic or subclavian vein. The proximal end of the lead is then tunneled below the fascia to the location of the pulse generator. Ventricular sensing and/or pacing electrode(s) may also be included at the distal end of the combined lead to provide ventricular intracardiac electrogram sensing and bradycardia pacing.

摘要翻译： 公开了一种用于植入式心律转复/除颤器系统的引导件。 在优选实施例中，引线将单个导管引线上的右心室心内膜电极，上腔静脉电极和一个或多个心房感测电极组合。 导管的远端经常植入，通常通过头部或锁骨下静脉中的切口。 引线的近端然后在筋膜下方隧道穿过脉冲发生器的位置。 心室感应和/或起搏电极也可以包括在组合导联的远端，以提供心室心电图检测和心动过缓起搏。

公开(公告)号：US5131388A

公开(公告)日：1992-07-21

申请号：US669646

申请日：1991-03-14

申请人： Benjamin D. Pless ,  William H. Elias ,  Timothy A. Marguit

发明人： Benjamin D. Pless ,  William H. Elias ,  Timothy A. Marguit

IPC分类号： A61N1/375 ,  A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/375

摘要： An implantable cardiac defibrillator is provided having an energy source, a capacitor, and means coupled to the energy source for charging the capacitor. The capacitor comprises a planar layered structure of anode plates, cathode plates and means separating the anode plates and cathode plates. A polymeric envelope containing electrolyte encloses the layered structure. Electrical contact means extend from the anodes and cathodes to outside the envelope.

公开(公告)号：US5014701A

公开(公告)日：1991-05-14

申请号：US354138

申请日：1989-05-19

申请人： Benjamin D. Pless ,  Kenneth J. Carroll

发明人： Benjamin D. Pless ,  Kenneth J. Carroll

IPC分类号： A61N1/39

CPC分类号： A61N1/3962

摘要： An implantable medical device includes electrodes coupled to a patient's heart and sensing circuitry having inputs connected to the electrodes for sensing cardiac electrical signals. The sensing circuitry includes a digital waveform analyzer system which performs direct analysis of digitized ECG heart signals from the atrial and/or ventricular channels. This eliminates the need for the system microprocessor to perform direct analysis on raw ECG data. The benefit being that complex software algorithms are not required, saving microprocessor memory space. System current drain is also reduced since the microprocessor need not be active during every ECG sample.

摘要翻译： 可植入医疗装置包括连接到患者心脏的电极和具有连接到电极的输入的感测电路，用于感测心脏电信号。 感测电路包括数字波形分析仪系统，其执行来自心房和/或心室通道的数字化ECG心脏信号的直接分析。 这样就无需系统微处理器对原始ECG数据进行直接分析。 好处是不需要复杂的软件算法，节省了微处理器的内存空间。 由于微处理器在每个ECG样本期间不需要有效，系统电流消耗也减少了。

公开(公告)号：US4989603A

公开(公告)日：1991-02-05

申请号：US505430

申请日：1990-04-06

申请人： Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： A61N1/39 ,  H03H19/00

CPC分类号： A61N1/3931 ,  H03H19/004

摘要： An implantable cardiac defibrillator employing a switched capacitor filter stage having charge steering resistors connected in series with corresponding switched capacitors that are coupled to a sensitive node of an operational amplifier. The stored channel charges in associated switches when they are turned off are directed away from the sensitive node. The switches associated with the switched capacitors are operated by control signals having a generally trapezoidal shaped waveform so as to slowly turn off the same, thereby reducing clock feedthrough and charge injection induced offset voltage on the output of the operational amplifier.

摘要翻译： 一种可植入心脏除颤器，其采用开关电容器滤波器级，其具有与耦合到运算放大器的敏感节点的相应开关电容器串联连接的电荷转向电阻器。 相关交换机关闭时存储的信道费用将远离敏感节点。 与开关电容器相关联的开关由具有大致梯形波形的控制信号操作，以便缓慢关闭开关电容器，从而减少运算放大器的输出端上的时钟馈通和电荷注入引起的失调电压。

公开(公告)号：US4872459A

公开(公告)日：1989-10-10

申请号：US199998

申请日：1988-05-27

申请人： Benjamin D. Pless ,  Michael B. Sweeney

发明人： Benjamin D. Pless ,  Michael B. Sweeney

IPC分类号： A61N1/362

CPC分类号： A61N1/3621

摘要： A heart pacemaker detects pace-terminable tachycardia conditions in the atrium of the heart in accordance with selected high rate, rate stability, sudden onset and sustained high rate criteria. When a pace-terminable tachycardia is detected, programmed treatment modalities are applied to attempt to terminate the tachycardia. The tachycardia is treated by applying timed bursts of electrical pulses in formats defined by programmed primary and secondary treatment modalities. The primary and secondary treatments may be applied in an order which is dependent upon the prior successful treatment of similar tachycardias. The pacemaker may also utilize remembered treatment values which were successfully applied to treat similar tachycardias. The pacemaker may be programmed to restart the primary and secondary modes of treatment in the event that the modes initially failed to terminate a tachycardia. The pacemaker may also be programmed to limit the rate of burst pulses to avoid overstimulating the heart.

摘要翻译： 心脏起搏器根据选择的高速率，速率稳定性，突然发作和持续的高速率标准检测心脏心房中的起搏性心动过速状况。 当检测到起搏性心动过速时，应用程序化治疗方式来试图终止心动过速。 通过以编程的初级和次级治疗方式定义的格式施加电脉冲的定时脉冲来治疗心动过速。 主要和次要治疗可以以依赖于先前成功治疗类似的心动过速的顺序来施用。 起搏器还可以利用成功应用于治疗类似心动过速的记忆治疗值。 起搏器可能被编程为在模式最初未能终止心动过速的情况下重新启动主要和次要治疗模式。 起搏器也可以被编程以限制脉冲脉冲的频率以避免过度刺激心脏。

公开(公告)号：US20110213441A1

公开(公告)日：2011-09-01

申请号：US13106729

申请日：2011-05-12

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： A61N1/36

CPC分类号： A61N1/36064 ,  A61N1/36082 ,  A61N1/36135 ,  A61N1/36178

摘要： This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.

公开(公告)号：US20110004268A1

公开(公告)日：2011-01-06

申请号：US12881143

申请日：2010-09-13

申请人： Thomas K. Tcheng ,  Robert E. Fischell ,  Benjamin D. Pless

发明人： Thomas K. Tcheng ,  Robert E. Fischell ,  Benjamin D. Pless

IPC分类号： A61N1/36

CPC分类号： A61N1/36067 ,  A61N1/36135

摘要： An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of supplying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected.

摘要翻译： 用于治疗运动障碍的可植入神经刺激器系统包括传感器，能够通过分析从传感器接收的信号来识别运动障碍发作的检测子系统，以及能够提供治疗性电刺激以治疗运动障碍的治疗子系统。 该系统通过检测运动障碍症状发作特征的生理条件来治疗运动障碍，并且当检测到这种病症时选择性地开始治疗。

公开(公告)号：US20100331717A1

公开(公告)日：2010-12-30

申请号：US12880138

申请日：2010-09-12

申请人： Benjamin D. Pless ,  Stephen T. Archer ,  Craig M. Baysinger ,  Barbara Gibb ,  Suresh Gurunathan ,  Bruce Kirkpatrick ,  Thomas K. Tcheng

发明人： Benjamin D. Pless ,  Stephen T. Archer ,  Craig M. Baysinger ,  Barbara Gibb ,  Suresh Gurunathan ,  Bruce Kirkpatrick ,  Thomas K. Tcheng

IPC分类号： A61B5/0476

CPC分类号： A61B5/4094 ,  A61B5/04012 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/6868 ,  A61B5/7203 ,  A61B5/7242 ,  A61B5/7246 ,  A61B5/7264 ,  A61B5/7275

摘要： A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.

摘要翻译： 使用可植入装置检测和预测神经病学的系统和方法使用与信号处理电路相关联的相对低功率的中央处理单元来识别特征（包括半波）并计算基于窗口的特征（包括线路长度和面积 在从患者的大脑接收的电图信号中波形的曲线）。 根据本发明的特征和基于窗口的特征可以以各种方式组合以实时检测和预测神经病学事件，从而能够实现可植入装置的响应动作。

公开(公告)号：US07643147B2

公开(公告)日：2010-01-05

申请号：US11556357

申请日：2006-11-03

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： G01B9/02

CPC分类号： G06K9/2036 ,  G06K9/00577

摘要： A method and system for performing device identification is disclosed. A source signal may be directed from an energy source towards the surface of a device for reflection therefrom. An interference pattern may be detected from the surface of the device, such as by a sensor. A determination as to whether a match exists between the representation of the interference pattern and a stored representation of an interference pattern may be performed. If a match exists, the device may be identified based on the stored representation of the interference pattern. Otherwise, a representation of the interference pattern may be stored and a unique identifier may be assigned to the stored representation of the interference pattern.

摘要翻译： 公开了一种用于执行设备识别的方法和系统。 源信号可以从能量源朝向装置的表面引导以从其反射。 可以从设备的表面（例如通过传感器）检测干涉图案。 可以执行关于在干涉图案的表示和存储的干涉图案的表示之间是否存在匹配的确定。 如果存在匹配，则可以基于存储的干涉图案的表示来识别该设备。 否则，可以存储干扰图案的表示，并且可以将唯一标识符分配给所存储的干涉图案的表示。