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公开(公告)号：US20070255347A1
公开(公告)日：2007-11-01
申请号：US11589698
申请日：2006-10-30
IPC分类号： A61N1/00
CPC分类号： A61N1/37252 , A61N1/0534 , A61N1/3605 , A61N1/37258 , A61N1/37264
摘要： The disclosure is directed to techniques for delivering electrical stimulation for patient notification. An implantable medical device (IMD) may deliver patient notification stimulation via one or more device site electrodes, e.g., electrodes located proximate to an implant site for the IMD, configured as cathodes. Anodes for delivery the patient notification stimulation may be located in an electrode array that is provided by one or more leads and located distally from the implant site, e.g., an electrode array located at one or more target sites for delivery of stimulation therapy. In some embodiments, the IMD may inhibit the patient notification stimulation for a period in response to input from the patient, and then resume the stimulation at the end of the period. In this manner, the notification stimulation may be “snoozed” like an alarm clock. When the stimulation resumes, it may be different, e.g., more urgent, then prior to inhibition.
摘要翻译： 本公开涉及用于递送用于患者通知的电刺激的技术。 可植入医疗装置（IMD）可以经由一个或多个装置位置电极（例如位于IMD的植入部位附近的电极）来配置患者通知刺激，该电极配置为阴极。 用于递送患者通知刺激的阳极可以位于由一个或多个引线提供并且位于远离植入位置的电极阵列中，例如位于一个或多个靶位点处的用于递送刺激治疗的电极阵列。 在一些实施例中，IMD可以响应于来自患者的输入而抑制患者通知刺激一段时间，然后在该期间结束时恢复刺激。 以这种方式，通知刺激可以像闹钟一样“延后”。 当刺激恢复时，它可能是不同的，例如更紧迫，然后在抑制之前。
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公开(公告)号：US07167756B1
公开(公告)日：2007-01-23
申请号：US09562221
申请日：2000-04-28
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/36142
摘要： An implantable medical device having an implantable power source such as a rechargeable lithium ion battery. The implantable medical device includes a recharge module that regulates the recharging process of the implantable power source using closed-loop feedback control. The recharge module includes a recharge regulator, a recharge measurement device monitoring at least one recharge parameter, and a recharge regulation control unit for regulating the recharge energy delivered to the power source in response to the recharge measurement device. The recharge module adjusts the energy provided to the power source to ensure that the power source is being recharged under safe levels.
摘要翻译： 一种具有可植入电源的可植入医疗装置，例如可充电锂离子电池。 可植入医疗装置包括充电模块，其使用闭环反馈控制来调节可植入电源的再充电过程。 再充电模块包括再充电调节器，监视至少一个再充电参数的再充电测量装置，以及用于响应于再充电测量装置调节传送到电源的再充电能量的再充电调节控制单元。 充电模块调整提供给电源的能量，以确保电源在安全水平下充电。
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公开(公告)号：US09682243B2
公开(公告)日：2017-06-20
申请号：US13360531
申请日：2012-01-27
摘要： This disclosure describes techniques for a method of charging a battery. In an example, the method includes charging the battery during a first charging session until a first charging termination parameter value is reached. The method also includes determining, for a second charging session, a second charging termination parameter value based on a duration of the first charging session, wherein the second charging termination parameter value is different than the first charging termination parameter value. The method also includes charging the battery during the second charging session until the second charging termination parameter value is reached.
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公开(公告)号：US09333350B2
公开(公告)日：2016-05-10
申请号：US12425903
申请日：2009-04-17
申请人： Mark T. Rise , Jonathon E. Giftakis , Paul H. Stypulkowski , Timothy J. Denison , Nathan A. Torgerson
发明人： Mark T. Rise , Jonathon E. Giftakis , Paul H. Stypulkowski , Timothy J. Denison , Nathan A. Torgerson
CPC分类号： A61N1/36082 , A61B5/01 , A61B5/0488 , A61B5/08 , A61B5/0816 , A61B5/165 , A61B5/441 , A61B5/4836 , A61B5/7275 , G06F19/00 , G16H20/70 , G16H40/63
摘要： A therapy system for managing a psychiatric disorder of the patient may be controlled based on a patient mood state. Therapy may be delivered to a patient according to a therapy program, and a physiological parameter of the patient may be monitored during or after therapy delivery. The patient mood state may be determined based on the monitored physiological parameter, and the therapy delivery may be controlled based on the determined mood state. In some embodiments, the therapy delivery is stopped prior to determining the patient mood state and the therapy delivery is restarted upon detecting a negative mood state. In other embodiments, therapy delivery is delivered until a positive mood state is detected, at which point the therapy delivery may be stopped.
摘要翻译： 可以基于患者情绪状态来控制用于管理患者精神障碍的治疗系统。 治疗可以根据治疗程序递送到患者，并且可以在治疗递送期间或之后监测患者的生理参数。 可以基于所监测的生理参数来确定患者情绪状态，并且可以基于所确定的情绪状态来控制治疗递送。 在一些实施例中，在确定患者情绪状态之前停止治疗递送，并且在检测到负情绪状态时重新开始治疗递送。 在其它实施方案中，递送治疗递送直到检测到正状态，此时可以停止治疗递送。
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公开(公告)号：US09259571B2
公开(公告)日：2016-02-16
申请号：US12603316
申请日：2009-10-21
CPC分类号： A61N1/08 , A61N1/00 , A61N1/36125
摘要： This disclosure describes generation of electrical stimulation pulses for electrical stimulation therapy. The stimulation pulses have a pulse current level and pulse width, and may be generated by a current regulator. The pulse voltage level may be a voltage level delivered by the current regulator while maintaining regulation of the pulse current level. During delivery of a pulse, a supply voltage level may decrease due to discharging of a supply capacitance, and the pulse voltage level may increase due to charging of a load capacitance. The pulse current level may be controlled to decrease during the pulse width such that a sum of the pulse voltage level and a headroom voltage of the current regulator does not exceed the supply voltage level. In some examples, the pulse may include sub-pulses with different sub-pulse current levels, where an earlier sub-pulse has a higher pulse current level than a later sub-pulse.
摘要翻译： 本公开描述了用于电刺激治疗的电刺激脉冲的产生。 刺激脉冲具有脉冲电流电平和脉冲宽度，并且可以由电流调节器产生。 脉冲电压电平可以是由电流调节器传递的电压电平，同时保持脉冲电流电平的调节。 在传送脉冲期间，由于供电电容的放电，电源电压电平可能降低，并且由于负载电容的充电而导致的脉冲电压电平可能增加。 可以在脉冲宽度期间控制脉冲电流水平降低，使得电流调节器的脉冲电压电平和余量电压之和不超过电源电压电平。 在一些示例中，脉冲可以包括具有不同子脉冲电流电平的子脉冲，其中较早的子脉冲具有比稍后的子脉冲更高的脉冲电流电平。
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46.发明授权Flagging of electrodes of an implantable medical device, controller, system and method therefore 有权因此可植入医疗器械的电极的标记，控制器，系统和方法公开(公告)号：US09238135B2
公开(公告)日：2016-01-19
申请号：US12112612
申请日：2008-04-30
CPC分类号： A61N1/08 , A61N1/36071 , A61N1/36185
摘要： Method, controller and system for an implantable medical device having a plurality of electrodes, the implantable medical device capable of delivering therapeutic stimulation to a patient, comprising a control module, a user interface operatively coupled to the control module, the user interface providing control of the control module by a medical professional or other user, and an electrode interface operatively coupled between the plurality of electrodes and the control module. The control module uses the electrode interface to obtain a plurality of measurements of impedance values for a plurality of selected pairs of individual ones of the plurality of electrodes. The control module flags electrodes using the plurality of measurements of impedance values of the selected pairs of individual ones of the plurality of electrodes comparative to a range, and the delivery of therapy on flagged electrodes is inhibited.
摘要翻译： 用于具有多个电极的可植入医疗装置的方法，控制器和系统，所述可植入医疗装置能够向患者递送治疗刺激，所述可植入医疗装置包括控制模块，可操作地耦合到所述控制模块的用户界面，所述用户界面提供 医疗专业人员或其他用户的控制模块以及可操作地耦合在多个电极和控制模块之间的电极接口。 所述控制模块使用所述电极接口来获得所述多个电极中的多个所选择的对中的多个所选对的多个测量值。 控制模块使用多个电极中所选择的多个电极对的多个阻抗值的测量来标记电极，与一个范围相比较，并且禁止在标记的电极上进行治疗。
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公开(公告)号：US08649872B2
公开(公告)日：2014-02-11
申请号：US13310136
申请日：2011-12-02
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/36082 , A61N1/36185 , Y10S128/903
摘要： A programmer allows a clinician to identify combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The programmer executes an electrode combination search algorithm to select combinations of electrodes to test in a non-random order. According to algorithms consistent with the invention, the programmer may first identify a position of a first cathode for subsequent combinations, and then select electrodes from the set to test with the first cathode as anodes or additional cathodes based on the proximity of the electrodes to the first cathode. The programmer may store information for each combination tested, and the information may facilitate the identification of desirable electrode combinations by the clinician. The clinician may create neurostimulation therapy programs that include identified desirable program combinations.
摘要翻译： 程序员允许临床医生从植入在患者体内的电极组中识别电极的组合，其能够通过可植入医疗装置递送所需的神经刺激疗法。 编程器执行电极组合搜索算法以选择电极的组合以非随机顺序进行测试。 根据与本发明一致的算法，程序员可以首先识别用于后续组合的第一阴极的位置，然后基于电极与电极的接近度，从第一阴极中选择电极作为阳极或附加阴极进行测试 第一阴极。 程序员可以存储每个测试组合的信息，并且该信息可以有助于由临床医生识别期望的电极组合。 临床医生可以创建神经刺激治疗程序，其包括所识别的期望程序组合。
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48.发明授权公开(公告)号：US08538538B2
公开(公告)日：2013-09-17
申请号：US12829108
申请日：2010-07-01
IPC分类号： A61N1/05
CPC分类号： A61N1/3605 , A61N1/0534 , A61N1/0553 , A61N1/36017 , A61N1/36025 , A61N1/37247
摘要： This disclosure describes delivery of omnipolar electrical stimulation with an external electrical stimulator. Omnipolar electrical stimulation may involve stimulation with an electrode carried on the housing of an implantable medical device (IMD) while substantially simultaneously delivering stimulation via one or more implanted electrodes having the same polarity as the electrode on the housing. An external medical device (EMD) may simulate the IMD housing electrode with an electrode separate from the electrodes carried on leads implanted near target tissue. This electrode may be an external electrode carried on the external housing of the EMD or an external patch electrode. Alternatively, the electrode may be an implantable electrode coupled to the EMD. The conductivity of the external or implantable electrode may also be optimized to approximate the conductivity of the IMD housing electrode. This electrode coupled to the EMD may be utilized during trial stimulation or chronic, external, stimulation.
摘要翻译： 本公开描述了用外部电刺激器递送全极电刺激。 全极性电刺激可涉及利用携带在可植入医疗装置（IMD）的壳体上的电极进行刺激，同时通过一个或多个与壳体上的电极极性相同的注入电极输送刺激。 外部医疗设备（EMD）可以模拟IMD外壳电极，其中电极与植入靶组织附近的导线上携带的电极分开。 该电极可以是承载在EMD的外壳上的外部电极或外部贴片电极。 或者，电极可以是耦合到EMD的可植入电极。 外部或可植入电极的导电性也可以被优化以接近IMD外壳电极的导电性。 耦合到EMD的该电极可以在试验刺激或慢性，外部刺激期间使用。
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49.发明授权Multi-stage testing of electrodes of implantable medical device, system and method 有权可植入医疗器械电极的多级测试，系统和方法公开(公告)号：US08195294B2
公开(公告)日：2012-06-05
申请号：US12112460
申请日：2008-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/36521 , A61N1/36185 , A61N1/37247
摘要： Method, controller and system for an implantable medical device capable of delivering therapeutic stimulation through a plurality of electrodes. A control module is operable to conduct a plurality of measurements of impedance values creating a plurality of measured impedance values for a plurality of selected sets of individual ones of the plurality of electrodes based on a plurality of active parameters. The control module conducts the plurality of measurements of impedance values in a plurality of stages in which at least one of said plurality of active parameters is varied between individual ones of the plurality of stages.
摘要翻译： 一种能够通过多个电极传递治疗刺激的可植入医疗装置的方法，控制器和系统。 控制模块可操作以基于多个有效参数进行阻抗值的多个测量，从而产生多个选定组的多个电极中的多个测量的阻抗值。 所述控制模块在所述多个级中的各个阶段之间变化所述多个有效参数中的至少一个有效参数的多个级中进行阻抗值的多个测量。
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公开(公告)号：US08068915B2
公开(公告)日：2011-11-29
申请号：US11698655
申请日：2007-01-26
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/36082 , A61N1/36185 , Y10S128/903
摘要： A programmer allows a clinician to identify desirable combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The clinician may create neurostimulation therapy programs that include identified desirable electrode combinations. In some embodiments, the clinician may use the programmer to select a program, such as a program identified during a neurostimulation programming session, and direct the programmer to replicate the selected program. The programmer may change one or more parameters of the selected program, such as pulse amplitude or duty cycle, when generating the copy of the selected program. In some embodiments, the programmer may associate each of a plurality of programs identified during a neurostimulation therapy programming session with one or more program categories, and may automatically generate program groups that include two or more of the programs based on the program categories.
摘要翻译： 程序员允许临床医生从植入患者体内的电极组中识别电极的期望组合，从而能够通过可植入医疗装置递送所需的神经刺激疗法。 临床医生可以产生神经刺激治疗程序，其包括所识别的期望的电极组合。 在一些实施例中，临床医生可以使用编程器来选择程序，诸如在神经刺激编程会话期间识别的程序，并指示程序员复制所选择的程序。 当生成所选程序的副本时，编程器可以改变所选程序的一个或多个参数，例如脉冲幅度或占空比。 在一些实施例中，程序员可以将在神经刺激治疗程序设计会话期间识别的多个程序中的每一个与一个或多个程序类别相关联，并且可以基于程序类别自动生成包括两个或更多程序的程序组。
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