Chromosome 11-linked coronary heart disease susceptibility gene CHD1
    41.
    发明授权
    Chromosome 11-linked coronary heart disease susceptibility gene CHD1 失效
    染色体11连锁冠心病易感基因CHD1

    公开(公告)号:US06225451B1

    公开(公告)日:2001-05-01

    申请号:US09262773

    申请日:1999-03-04

    IPC分类号: C07H2104

    摘要: Human coronary heart disease susceptibility gene (CHD1), some alleles of which are related to susceptibility to coronary heart disease. Germline mutations in the CHD1 gene and their use in the diagnosis of predisposition to coronary heart disease and to metabolic disorders, including hypoalphalipoproteinemia, familial combined hyperlipidemia, insulin resistant syndrome X or multiple metabolic disorder, obesity, diabetes and dyslipidemic hypertension. Presymptomatic therapy of individuals who carry deleterious alleles of the CHD1 gene (including gene therapy, protein replacement therapy, and administration of protein mimetics and inhibitors). The screening of drugs for dyslipidemic therapy.

    摘要翻译: 人类冠心病易感基因(CHD1),其中一些等位基因与冠心病易感性有关。 CHD1基因中的种系突变及其在诊断冠心病和代谢障碍(包括低脂蛋白血症,家族性联合高脂血症,胰岛素抵抗综合征X或多种代谢紊乱,肥胖,糖尿病和血脂异常高血压)中的应用。 携带CHD1基因有害等位基因的个体(包括基因治疗,蛋白质替代疗法和蛋白质模拟物和抑制剂的给药)的症状治疗。 筛查药物用于血脂异常治疗。

    Automated tools for building secure software programs
    42.
    发明授权
    Automated tools for building secure software programs 有权
    用于构建安全软件程序的自动化工具

    公开(公告)号:US09418230B2

    公开(公告)日:2016-08-16

    申请号:US14163523

    申请日:2014-01-24

    IPC分类号: G06F11/36 G06F21/57

    CPC分类号: G06F21/577 G06F2221/033

    摘要: A computer implemented tool is described that includes an assertion generator module that can automatically generate assertions, which are usable to verify application-specific security properties, for a computer software program. An assertion checker module can automatically analyze the computer software program to ensure that it satisfies the application-specific security properties. A graphical user interface module can display feedback to diagnose security flaws detected in the computer software program based on the analysis by the assertion checker module. In support of these modules are a code preprocessor module that can translate source code of the computer software program into an intermediate abstract representation, and a database module that can store the generated assertions and associated data in a database. Each of the modules can provide functionality at any time during code construction of the computer software program.

    摘要翻译: 描述了一种计算机实现的工具,其包括断言生成器模块,其能够自动生成用于计算机软件程序的可用于验证应用程序特定的安全属性的断言。 断言检查模块可以自动分析计算机软件程序,以确保其满足应用程序特定的安全属性。 图形用户界面模块可以显示反馈信息,以根据断言检查模块的分析来诊断计算机软件程序中检测到的安全漏洞。 支持这些模块是可以将计算机软件程序的源代码转换为中间抽象表示的代码预处理器模块,以及可以将生成的断言和关联数据存储在数据库中的数据库模块。 每个模块可以在计算机软件程序的代码构建期间随时提供功能。

    Fluid-heating apparatus and methods of operating the same
    43.
    发明授权
    Fluid-heating apparatus and methods of operating the same 有权
    流体加热装置及其操作方法

    公开(公告)号:US08530799B2

    公开(公告)日:2013-09-10

    申请号:US11392988

    申请日:2006-03-29

    IPC分类号: F22B1/28

    CPC分类号: H05B3/82 F24H9/2021

    摘要: Systems and methods of heating an accurate quantity of a fluid. A determination is made that an event in which a relatively large quantity of hot water is used has occurred. One or more temperatures are sensed. An increase in a temperature set point is made if the sensed temperatures indicate a shortage of hot water for the event. A decrease in the temperature set point is made if the sensed temperatures indicate an excess of hot water was available for the event. No change is made to the temperature set point if the quantity of hot water available for the event was appropriate.

    摘要翻译: 加热精确量的流体的系统和方法。 确定发生了使用相对大量的热水的事件。 感测到一个或多个温度。 如果感测到的温度表示事件的热水不足,则会增加温度设定值。 如果感测到的温度表明过热的热水可用于事件,则会降低温度设定值。 如果事件可用的热水量是适当的,温度设定点没有变化。

    Mixed energy heater with constant temperature control
    44.
    发明授权
    Mixed energy heater with constant temperature control 有权
    混合能量加热器具有恒温控制

    公开(公告)号:US08437626B2

    公开(公告)日:2013-05-07

    申请号:US12573975

    申请日:2009-10-06

    IPC分类号: F24C1/00

    摘要: A type of mixed energy heater with constant temperature control, which belongs to the field of water heater technology. This water heater includes a gas heating portion, an electric heating portion, and a control circuit. The control circuit includes a power output controller. The electric heating portion is composed of water passage and electric heating device installed in the water passage. The water passages of the gas heating portion and the electric heating portion are connected together in series or in parallel, and the terminal of the passage is equipped with a temperature sensor. The output of the temperature sensor is connected to the signal input of the control circuit.

    摘要翻译: 一种具有恒温控制的混合能量加热器,属于热水器技术领域。 该热水器包括气体加热部分,电加热部分和控制电路。 控制电路包括功率输出控制器。 电加热部分由水通道和安装在水道中的电加热装置组成。 气体加热部分和电加热部分的水通道串联或并联连接在一起,并且通道的端子配备有温度传感器。 温度传感器的输出端连接到控制电路的信号输入端。

    User feedback method and system for business suite customization
    45.
    发明授权
    User feedback method and system for business suite customization 失效
    用户反馈方法和系统的业务套件定制

    公开(公告)号:US08380635B2

    公开(公告)日:2013-02-19

    申请号:US12845120

    申请日:2010-07-28

    IPC分类号: G06Q20/00

    摘要: A computer-implemented user feedback method, system and program product for customizing business suite software that is executable on a computer system. The method includes: acquiring a business logic software function associated with a feedback mechanism in a business suite software user interface for the business suite software; acquiring an existing customization requirement related to the business logic software function and the relationship between the existing customization requirement related to the business logic software function and another existing customization requirement related to the business logic software function; and presenting the acquired existing customization requirement and the relationship between the existing customization requirement related to the business logic software function and the other existing customization requirement related to the business logic software function. The system includes: a business logic software function collector; a customization requirement manager; and a customization requirement presenter.

    摘要翻译: 用于定制可在计算机系统上执行的业务套件软件的计算机实现的用户反馈方法,系统和程序产品。 该方法包括:在业务套件软件的业务套件软件用户界面中获取与反馈机制相关联的业务逻辑软件功能; 获取与业务逻辑软件功能相关的现有定制要求以及与业务逻辑软件功能相关的现有定制要求与业务逻辑软件功能相关的现有定制要求之间的关系; 并呈现所获得的现有定制要求以及与业务逻辑软件功能相关的现有定制要求与业务逻辑软件功能相关的其他现有定制要求之间的关系。 该系统包括:业务逻辑软件功能收集器; 定制需求经理; 和定制要求演示者。

    Visualizing and modeling interaction relationship among entities
    46.
    发明申请
    Visualizing and modeling interaction relationship among entities 失效
    实体之间的可视化和建模交互关系

    公开(公告)号:US20060004872A1

    公开(公告)日:2006-01-05

    申请号:US11170596

    申请日:2005-06-29

    IPC分类号: G06F17/00

    CPC分类号: G06Q10/08 G06Q10/06

    摘要: The present invention provides methods of visualizing and modeling the interaction relationship among entities. An example method of visualizing the interaction relationship among entities includes the steps of: presenting the internal logic of entity in an entity container; and presenting the interaction relationship among the entities in an interaction space. A method of modeling the interaction relationship among entities, includes the steps of: defining each entity related to said interaction relationship; defining an interface of said each entity in an interaction space; and defining interaction logics among said interfaces in the interaction space.

    摘要翻译: 本发明提供了可视化和建模实体之间的交互关系的方法。 可视化实体之间的交互关系的示例方法包括以下步骤:在实体容器中呈现实体的内部逻辑; 并在交互空间中呈现实体之间的交互关系。 一种对实体之间的交互关系进行建模的方法,包括以下步骤:定义与所述交互关系相关的每个实体; 在交互空间中定义所述每个实体的接口; 并在交互空间中定义所述接口之间的交互逻辑。

    MTF measuring method and system
    47.
    发明申请
    MTF measuring method and system 有权
    MTF测量方法和系统

    公开(公告)号:US20050100244A1

    公开(公告)日:2005-05-12

    申请号:US10981916

    申请日:2004-11-04

    CPC分类号: G01M11/0292 G06T7/66 G06T7/70

    摘要: A method of measuring a modulation transfer function (MTF) includes detecting the center of a line spread function (LSF) image in order to calculate an MTF. For this purpose, an enlarged image of a portion of an image containing the LSF image is created, and binary-coded based on a threshold. A morphological operation is performed on the binary-coded image. Coordinates representing points that define the contour of the resultant image are sampled, and used to work out coordinates representing the center of a circle through Hough transform. The coordinates representing the center are transformed into coordinates representing a point in an original image.

    摘要翻译: 测量调制传递函数(MTF)的方法包括检测线扩展函数(LSF)图像的中心,以便计算MTF。 为此,创建包含LSF图像的图像的一部分的放大图像,并且基于阈值进行二进制编码。 对二进制编码图像进行形态学操作。 对表示定义所得图像轮廓的点的坐标进行采样,并用于通过霍夫变换求出表示圆心的坐标。 表示中心的坐标被转换为表示原始图像中的点的坐标。

    Digital video signal encoder and encoding method
    48.
    发明授权
    Digital video signal encoder and encoding method 失效
    数字视频信号编码器和编码方法

    公开(公告)号:US6005626A

    公开(公告)日:1999-12-21

    申请号:US780780

    申请日:1997-01-09

    申请人: Wei Ding

    发明人: Wei Ding

    摘要: Motion vectors and associated errors which are determined in the course of encoding a video signal are used to determine whether respective macroblocks of two or more frames represent the same subject matter albeit displaced by motion represented by the frames. The motion vector errors are compared to a predetermined motion threshold. If a particular motion vector error is less than the motion threshold, the macroblocks corresponding to the motion vector error are determined to represent substantially identical subject matter and the corresponding motion vector represents displacement of the subject matter between the frames due to motion of the subject matter. Accordingly, differences between the macroblocks corresponding to the motion vector error are determined to be due primarily to noise and not to differences in the subject. Therefore, a relatively heavy temporal filter is applied between the macroblocks. Conversely, if a particular motion vector error is not less than the motion threshold, the macroblocks corresponding to the motion vector error are determined to represent different subject matter and only a spatial filter is applied to either macroblock. The spatial filter is applied relatively lightly to reduce noise while minimizing signal loss, e.g., blurring, resulting from the filtering. The motion threshold is set according to the noise variance of the video signal which is being encoded. The noise variance of the video signal can be measured using the video signal acquisition equipment used to acquire the video signal, e.g., a video camera, or can be estimated from the video signal itself.

    摘要翻译: 使用在编码视频信号的过程中确定的运动矢量和相关错误来确定两个或更多个帧的相应宏块是否表示相同的主题,尽管由帧所代表的运动所取代。 将运动矢量误差与预定运动阈值进行比较。 如果特定运动矢量误差小于运动阈值,则确定与运动矢量误差相对应的宏块以表示基本上相同的主题,并且相应的运动矢量表示由于主题的运动而导致的帧之间的主体的位移 。 因此,对应于运动矢量误差的宏块之间的差异被确定为主要是由噪声引起的,而不是主体的差异。 因此,在宏块之间应用相对较重的时间滤波器。 相反,如果特定运动矢量误差不小于运动阈值,则确定与运动矢量误差相对应的宏块以表示不同的主题,并且仅将空间滤波器应用于任一宏块。 相对较轻地施加空间滤波器以减少噪声,同时最小化由滤波产生的信号损失,例如模糊。 运动阈值根据正被编码的视频信号的噪声方差来设定。 可以使用用于获取视频信号的视频信号采集设备(例如,摄像机)来测量视频信号的噪声方差,或者可以从视频信号本身估计。

    Fixation device for intramedullary nail
    49.
    发明授权
    Fixation device for intramedullary nail 有权
    髓内钉固定装置

    公开(公告)号:US08409205B2

    公开(公告)日:2013-04-02

    申请号:US13349542

    申请日:2012-01-12

    IPC分类号: A61B17/56

    CPC分类号: A61B17/744 A61B17/7225

    摘要: A fixation device for an intramedullary nail for proximal femoral fractures, including a main intramedullary nail, a combined locking nail, and cortical bone screws. The main intramedullary nail has a longitudinal axis, a proximal end, and a distal end with a tip. The proximal end includes a through hole for assembling the combined locking nail. The distal end includes an oblong through hole and a circular through hole, both for receiving the cortical bone screws. The combined locking nail includes a head, a distal end of the locking nail, a sleeve, a connecting block, and a cover cap. The connecting block includes a left-handed external thread. The cover cap includes a left-handed internal thread matching with the external thread of the connecting block, a symmetrical sliding plane, and a protrusion block disposed at the end of the symmetrical sliding plane.

    摘要翻译: 用于股骨近端骨折的髓内钉固定装置,包括主髓内钉,组合锁定钉和皮质骨螺钉。 主髓内钉具有纵轴,近端和具有尖端的远端。 近端包括用于组装组合的锁钉的通孔。 远端包括长圆形通孔和圆形通孔,两者用于容纳皮质骨螺钉。 组合的锁钉包括头部,锁定钉的远端,套筒,连接块和盖帽。 连接块包括左手外螺纹。 盖帽包括与连接块的外螺纹相配合的左旋内螺纹,对称滑动平面和设置在对称滑动平面端部的突出块。