利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

75 条记录 (耗时 0.036 秒)

    Devices and methods for interstitial injection of biologic agents into tissue
    41.
    发明授权
    Devices and methods for interstitial injection of biologic agents into tissue 有权
    将生物制剂间插注入组织的装置和方法

    公开(公告)号：US08273072B2

    公开(公告)日：2012-09-25

    申请号：US12621037

    申请日：2009-11-18

    申请人： Scott E. Jahns ,  Gary S. Oehme ,  Matthew D. Bonner ,  James R. Keogh

    发明人： Scott E. Jahns ,  Gary S. Oehme ,  Matthew D. Bonner ,  James R. Keogh

    IPC分类号： A61M31/00

    CPC分类号： A61B17/3478 ,  A61B17/00234 ,  A61B17/205 ,  A61B2017/00247 ,  A61B2017/00876 ,  A61B2017/2936 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2018/00392 ,  A61B2090/034 ,  A61M5/32 ,  A61M2025/0086 ,  A61M2025/0087

    摘要： Apparatus and methods for injecting biological agents into tissue. Devices are provided having elongate shafts and distal injection heads for transversely driving needles into tissue and injecting medical agents into the tissue through the needles. A longitudinal force directed along the shaft can be translated to a needle driving force transverse to the shaft. Some devices provide controllably variable needle penetration depth. Devices include mechanical needle drivers utilizing four link pantographs, rack and pinions, and drive yokes for driving a first needle bearing body toward a second tissue contacting body. Other devices include inflatable members for driving and retracting needles. Still other devices include magnets for biasing the needles in extended and/or retracted positions. The invention includes minimally invasive methods for epicardially injecting cardiocyte precursor cells into infarct myocardial tissue.

    摘要翻译： 将生物制剂注入组织的装置和方法。 设备具有细长的轴和远端注射头，用于将针横向驱动到组织中，并通过针将药剂注射到组织中。 沿着轴引导的纵向力可以平移到与轴垂直的针驱动力​​。 一些装置提供可控的可变针穿透深度。 设备包括利用四个连杆缩放仪，齿条和小齿轮的机械针驱动器和用于将第一滚针轴承体朝向第二组织接触体驱动的驱动轭。 其他装置包括用于驱动和缩回针的可充气构件。 还有其它装置包括用于在延伸和/或缩回位置偏置针的磁体。 本发明包括用心外膜将心脏细胞前体细胞注入梗死心肌组织的微创方法。

    Electrosurgical methods and apparatus for making precise incisions in body vessels
    42.
    发明授权
    Electrosurgical methods and apparatus for making precise incisions in body vessels 有权
    电动手术方法和装置，用于精确切开体内血管

    公开(公告)号：US07976543B2

    公开(公告)日：2011-07-12

    申请号：US11698332

    申请日：2007-01-26

    申请人： Cynthia T. Clague ,  Philip J. Haarstad ,  Scott E. Jahns ,  James R. Keogh ,  Christopher P. Olig ,  Raymond W. Usher

    发明人： Cynthia T. Clague ,  Philip J. Haarstad ,  Scott E. Jahns ,  James R. Keogh ,  Christopher P. Olig ,  Raymond W. Usher

    IPC分类号： A61B18/14 ,  A61B18/18

    CPC分类号： A61B18/14 ,  A61B18/1482 ,  A61B2018/00386 ,  A61B2018/1407 ,  A61B2090/034 ,  A61B2090/036

    摘要： Methods and apparatus employed in surgery involving making precise incisions in vessels of the body, particularly cardiac blood vessels in coronary revascularization procedures conducted on the stopped or beating heart are disclosed. Such incisions are created by applying an elongated electrosurgical cutting electrode to the outer surface of the vessel wall in substantially parallel alignment with the body vessel axis, the elongated electrosurgical cutting electrode having a predetermined cutting electrode length exceeding the cutting electrode width. RF energy is applied between the electrosurgical cutting electrode and the ground electrode at an energy level and for a duration sufficient to cut an elongated slit through the vessel wall where the elongated electrosurgical cutting electrode is applied to the surface of the vessel wall.

    摘要翻译： 公开了涉及在停止或跳动的心脏进行的冠状动脉血运重建手术中精确切开身体血管，特别是心脏血管的手术方法和装置。 这种切口是通过将细长的电外科切割电极以与体血管轴线基本平行对准的方式将细长的电外科切割电极施加到血管壁的外表面而形成的，细长的电外切割电极具有超过切割电极宽度的预定切割电极长度。 RF能量在电外科切割电极和接地电极之间以能量水平施加，持续时间足以切割通过血管壁的细长狭缝，其中细长的电外科切割电极被施加到血管壁的表面。

    METHOD AND SYSTEM FOR NERVE STIMULATION AND CARDIAC SENSING PRIOR TO AND DURING A MEDICAL PROCEDURE
    43.
    发明申请
    METHOD AND SYSTEM FOR NERVE STIMULATION AND CARDIAC SENSING PRIOR TO AND DURING A MEDICAL PROCEDURE 有权
    在医疗过程中和之后进行神经刺激和心脏感知的方法和系统

    公开(公告)号：US20100004708A1

    公开(公告)日：2010-01-07

    申请号：US12557950

    申请日：2009-09-11

    申请人： Scott E. Jahns ,  Michael R.S. Hill ,  James R. Keogh

    发明人： Scott E. Jahns ,  Michael R.S. Hill ,  James R. Keogh

    IPC分类号： A61N1/362 ,  A61N1/36

    CPC分类号： A61N1/056 ,  A61N1/36114 ,  A61N1/362 ,  A61N1/36514 ,  A61N1/385 ,  A61N1/39

    摘要： A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. A sensor to sense a characteristic of a fluid or tissue, such as an impending contraction, may be also used during the medical procedure. Systems and devices for performing the medical procedure are also provided.

    摘要翻译： 提供了一种执行诸如手术的医疗程序的方法。 刺激神经以将心脏的跳动调节到第一状态，例如停止或减缓的状态。 医疗程序在心脏或另一个器官上进行。 停止对神经的刺激，以便将心脏的跳动调节到第二状态，例如打浆状态。 心脏本身也可能被刺激到跳动状态，例如通过起搏。 可以继续刺激神经以允许继续医疗程序。 也可以在医疗过程中使用用于感测流体或组织的特征的传感器，例如即将收缩的收缩。 还提供用于执行医疗程序的系统和设备。

    Methods and apparatus for locating body vessels and occlusions in body vessels
    44.
    发明授权
    Methods and apparatus for locating body vessels and occlusions in body vessels 有权
    用于定位体内血管和闭塞的方法和装置

    公开(公告)号：US07493154B2

    公开(公告)日：2009-02-17

    申请号：US10278531

    申请日：2002-10-23

    申请人： Matthew D. Bonner ,  Cynthia T. Clague ,  Scott E. Jahns ,  James R. Keogh

    发明人： Matthew D. Bonner ,  Cynthia T. Clague ,  Scott E. Jahns ,  James R. Keogh

    IPC分类号： A61B5/05

    CPC分类号： A61B5/06 ,  A61B5/062 ,  A61B2017/00022 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/22001 ,  A61B2090/061

    摘要： Methods and apparatus employed to locate body vessels and occlusions in body vessels finding particular utility in cardiac surgery, particularly minimally invasive cardiac surgery to locate cardiac arteries and occlusions in cardiac arteries are disclosed. An elongated vessel lumen probe incorporating a lumen probe element at or near the elongated vessel lumen probe distal end is advanced into the vessel lumen. A vessel surface probe manipulated by the surgeon and having a surface probe element sensor is employed to detect the lumen probe element and to follow the progress of the vessel lumen probe element as it approaches and is advanced through or is blocked by an occlusion. In the location of a coronary artery, the surface probe element sensor is moved about against the epicardium over the suspected location of the artery of interest until a surface probe element sensor of the present invention at the surface probe distal end interacts with the lumen probe element of the vessel lumen probe.

    摘要翻译： 公开了用于定位身体血管和身体血管闭塞的方法和装置，其在心脏手术中特别有用，特别是在心脏动脉中定位心脏动脉和闭塞的微创心脏手术。 在细长血管腔探针末端处或其附近并入管腔探针元件的细长血管腔探针被推入血管内腔。 由外科医生操作并具有表面探针元件传感器的血管表面探针被用于检测内窥镜元件，并且随着血管腔探针元件的进入而进入并被阻塞阻塞。 在冠状动脉的位置，表面探针元件传感器在目标动脉的疑似位置上靠近心外膜移动，直到本发明的表面探针元件传感器在表面探针远端与内腔探针元件相互作用 的血管腔探针。

    Testicular Prosthesis
    49.
    发明申请
    Testicular Prosthesis 审中-公开
    睾丸假体

    公开(公告)号：US20080177385A1

    公开(公告)日：2008-07-24

    申请号：US12016535

    申请日：2008-01-18

    申请人： Scott E. Jahns

    发明人： Scott E. Jahns

    IPC分类号： A61F2/02

    CPC分类号： A61F2/0059 ,  A61F2250/0003

    摘要： A testicular prosthesis includes a flexible bladder, a fill port, and a plug. The flexible bladder incorporates an interior chamber. The fill port is coupled to the flexible bladder and generally includes a cylindrical tube that extends through the bladder. The cylindrical tube is defined by an interior wall and forms an opening to the interior chamber of the bladder. The plug is a cylindrical member that is coaxial to the bore. A seal is formed between the cylindrical member of the plug and the interior wall of the fill port.

    摘要翻译： 睾丸假体包括柔性囊，填充口和塞子。 柔性气囊包括一个内部腔室。 填充口连接到柔性囊，并且通常包括延伸穿过囊的圆柱形管。 圆柱形管由内壁限定，并形成到囊的内部室的开口。 插塞是与孔同轴的圆柱形构件。 在插头的圆柱形构件和填充口的内壁之间形成密封。