利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

51 条记录 (耗时 0.04 秒)

    Dehydrooligopeptides, their production and their medicinal use
    42.
    发明授权
    Dehydrooligopeptides, their production and their medicinal use 失效
    脱氢寡肽，其生产和药用

    公开(公告)号：US4276288A

    公开(公告)日：1981-06-30

    申请号：US82451

    申请日：1979-10-09

    申请人： Eugen Etschenberg ,  Wolfgang Opitz ,  Siegfried Raddatz

    发明人： Eugen Etschenberg ,  Wolfgang Opitz ,  Siegfried Raddatz

    IPC分类号： C07D263/42 ,  A61K38/00 ,  A61P35/00 ,  C07D213/54 ,  C07D307/54 ,  C07D333/24 ,  C07D333/38 ,  C07K1/113 ,  C07K5/06 ,  C07K5/065 ,  C07K5/078 ,  C07K5/08 ,  C07K5/087 ,  C07K5/097 ,  A61K37/00 ,  C07C103/52

    CPC分类号： C07K5/06034 ,  C07D213/54 ,  C07D307/54 ,  C07D333/24 ,  C07D333/38 ,  C07K5/06078 ,  C07K5/06139 ,  C07K5/0812 ,  C07K5/0821

    摘要： New dehydrooligopepetides which bear, as one terminal substituent, an optionally substituted alkyl or alkenyl, optionally substituted aryl, optionally substituted heterocyclic radical, optionally substituted aralkyl or aralkenyl or a carbamoyl group and as the other terminal substituent a hydroxyl or amino, an optionally substituted alkylamino, optionally substituted arylamino, optionally substituted aralkylamino, an optionally substituted nitrogen-containing heterocyclic radical with five or six ring members optionally containing a further heteroatom, optionally substituted aralkoxy, optionally substituted alkoxy, optionally substituted aryloxy, optionally substituted alkylthio group or optionally substituted hydrazine demonstrate histolytic and tumor-resolving activity. The compounds are prepared by either hydrolyzing or aminolyzing the corresponding 2,4-disubstituted 5(4H)-oxazolones.

    摘要翻译： 作为一个末端取代基，任选取代的烷基或烯基，任选取代的芳基，任选取代的杂环基，任选取代的芳烷基或芳烯基或氨基甲酰基并且作为另一个末端取代基的羟基或氨基，任选取代的烷基氨基 任选取代的芳基氨基，任选取代的芳烷基氨基，任选取代的含氮杂环基与五或六个环成员任选地含有另外的杂原子，任选取代的芳烷氧基，任选取代的烷氧基，任选取代的芳氧基，任选取代的烷硫基或任选取代的肼表明 组织溶解和肿瘤分解活性。 通过水解或氨基化相应的2,4-二取代的5（4H） - 恶唑酮来制备化合物。

    METHOD FOR CONTROLLING THE ADVANCEMENT OF THE WEAR-AWAY WIRE ELECTRODE OF WELDING AND/OR SOLDERING SYSTEMS AND SUCH A WELDING AND/OR SOLDERING SYSTEM
    44.
    发明申请
    METHOD FOR CONTROLLING THE ADVANCEMENT OF THE WEAR-AWAY WIRE ELECTRODE OF WELDING AND/OR SOLDERING SYSTEMS AND SUCH A WELDING AND/OR SOLDERING SYSTEM 审中-公开
    用于控制焊接和/或焊接系统的耐磨电线电极的方法，以及焊接和/或焊接系统

    公开(公告)号：US20120285939A1

    公开(公告)日：2012-11-15

    申请号：US13512067

    申请日：2010-12-16

    申请人： Udo-Ralf Kessler ,  Ralf Hellmig ,  Siegfried Raddatz

    发明人： Udo-Ralf Kessler ,  Ralf Hellmig ,  Siegfried Raddatz

    IPC分类号： B23K9/10

    CPC分类号： B23K9/124 ,  B23K9/1333 ,  B65H51/30

    摘要： The present invention relates to a method for universally controlling the advancement of the wear-away wire electrode (3) of welding and/or soldering systems, wherein the wire electrode (3) is taken from a wire supply (2) and fed to a welding head (8) from the wire supply (2) through a protective tube (1), wherein the wire electrode (3) is both advanced by means of a push drive (4) and pulled by means of a pull drive (5), which are preferably arranged in the region of the respective ends of the protective tube (1) that are actuated in keeping with a required advancement speed of the wire electrode (3). The pull drive is controlled in accordance with the actuating signals for the push drive.

    摘要翻译： 本发明涉及一种用于普遍地控制焊接和/或焊接系统的磨损线电极（3）的推进的方法，其中线电极（3）从电线（2）取出并馈送到 焊接头（8）通过保护管（1）从电线供应器（2）焊接，其中线电极（3）都通过推动驱动器（4）前进，并通过拉动驱动器（5）拉动， ，其优选地布置在保护管（1）的相应端部的区域中，其被驱动以保持线电极（3）的所需提前速度。 拉动驱动器根据推动驱动器的启动信号进行控制。

    Tryptamine derivatives active on central nervous system
    50.
    发明授权
    Tryptamine derivatives active on central nervous system 失效
    色胺衍生物在中枢神经系统上活跃

    公开(公告)号：US4870085A

    公开(公告)日：1989-09-26

    申请号：US175066

    申请日：1988-03-30

    申请人： Thomas Glaser ,  Siegfried Raddatz ,  Jorg Traber ,  Allen, George

    发明人： Thomas Glaser ,  Siegfried Raddatz ,  Jorg Traber ,  Allen, George

    IPC分类号： A61K31/40 ,  A61K31/4427 ,  A61K31/445 ,  A61P9/06 ,  A61P9/10 ,  A61P25/20 ,  A61P43/00 ,  C07D209/16 ,  C07D401/06 ,  C07D403/06

    CPC分类号： C07D401/06 ,  C07D209/16

    摘要： Novel tryptamines of the formula ##STR1## in which X is an alkylene chain or 2 to 4 carbon atoms wherein a carbon atom may be replaced by O or N-lower alkyl, and wherein a carbon atoms may be substituted by lower alkyl,R is hydrogen, lower alkyl, lower alkoxy, phenyl-lower alkyl, phenyl-lower alkoxy, hydroxy, amino-lower alkyl, fluorine, chlorine, bromine, cyano, carbamoyl or azido,R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each independently is hydrogen or lower alkyl,R.sup.5 is hydrogen, R.sup.6 --CO-- or R.sup.6 --SO.sub.2 --, andR.sup.6 is amino, lower alkoxy, phenyl or lower alkyl-phenyl,or dimers or salts thereof, are effective in treating disorders of the central nervous system.

    摘要翻译： 其中X是亚烷基链或2至4个碳原子的式（IMAGE）的新型色胺，其中碳原子可被O或N-低级烷基取代，并且其中碳原子可以被低级烷基取代，R是 氢，低级烷基，低级烷氧基，苯基 - 低级烷基，苯基 - 低级烷氧基，羟基，氨基 - 低级烷基，氟，氯，溴，氰基，氨基甲酰基或叠氮基，R1，R2，R3和R4各自独立地为氢或低级 烷基，R5是氢，R6-CO-或R6-SO2-，R6是氨基，低级烷氧基，苯基或低级烷基 - 苯基，或其二聚体或其盐在治疗中枢神经系统疾病中是有效的。