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    Methods of making L-amino acids in coryneform using the sigE gene
    41.
    发明授权
    Methods of making L-amino acids in coryneform using the sigE gene 失效
    使用sigE基因在棒状细胞中制备L-氨基酸的方法

    公开(公告)号：US06913908B2

    公开(公告)日：2005-07-05

    申请号：US09935757

    申请日：2001-08-24

    申请人： Bettina Möckel ,  Thoams Hermann ,  Mike Farwick ,  Michael Binder ,  Walter Pfefferle

    发明人： Bettina Möckel ,  Thoams Hermann ,  Mike Farwick ,  Michael Binder ,  Walter Pfefferle

    IPC分类号： C07K14/34 ,  C12P13/08 ,  C12P13/04

    CPC分类号： C12R1/15 ,  C07K14/34 ,  C12P13/08

    摘要： The present invention relates lo an isolated polynucleotide from Corynebacterium glutamicum comprising a polynucleotide sequence chosen from the group c insisting of (a) a polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID NO: 2; (b) a polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID NO: 2; (c) a polynucleotide which is complementary to the polynucleotides of(a) or (b), and (d) a polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of (a), (b), or (c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the sigE gene is present in enhanced form, and the use of polynucleotides which comprise the sequence according to the invention as hybridization probes.

    摘要翻译： 本发明涉及一种来自谷氨酸棒杆菌的分离的多核苷酸，其包含选自下组的多核苷酸序列，所述多核苷酸序列坚持：（a）与编码多肽的多核苷酸的程度相同的多核苷酸，所述多核苷酸包含氨基 SEQ ID NO：2的酸序列; （b）编码多肽的多核苷酸，其包含与SEQ ID NO：2的氨基酸序列至少70％的程度相同的氨基酸序列; （c）与（a）或（b）的多核苷酸互补的多核苷酸，和（d）包含（a），（b）或（c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸， 以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少sigE基因以增强形式存在，以及使用包含根据本发明的序列的多核苷酸作为杂交探针。

    Skin examination device
    45.
    发明授权
    Skin examination device 失效
    皮肤检查装置

    公开(公告)号：US6032071A

    公开(公告)日：2000-02-29

    申请号：US849439

    申请日：1997-05-30

    申请人： Michael Binder

    发明人： Michael Binder

    IPC分类号： A61B5/103 ,  A61B5/00

    CPC分类号： A61B5/0059 ,  A61B5/444 ,  A61B5/6844 ,  A61B5/6886

    摘要： A device for optical examination of human skin and its pigmentation comprises a cylindrical housing in which are arranged an optical observation device and a vertical illumination device. Where it faces the skin the housing is delimited by a plate made of transparent plastics or glass, which is applied to a skin site to be examined without introducing an immersion fluid. Light polarization devices are situated between the illumination device and the transparent plate and between the transparent plate and the optical observation device, their degree of polarization being controlled or, optionally, their location being movable mechanically into or out of particular light beam paths.

    摘要翻译： PCT No.PCT / AT95 / 00231 Sec。 371日期1997年5月30日 102（e）日期1997年5月30日PCT提交1995年11月28日PCT公布。 WO96 / 16698 PCT公开号 日期1996年6月6日人体皮肤光学检查装置及其色素沉着包括圆柱形壳体，其中配置有光学观察装置和垂直照明装置。 在面对皮肤的地方，外壳由透明塑料或玻璃制成的板材界定，该板材应用于待检查的皮肤部位而不引入浸没液体。 光偏振装置位于照明装置和透明板之间，并且在透明板和光学观察装置之间，它们的偏振度被控制，或者可选地，它们的位置可以机械地移动进入或离开特定的光束路径。

    Fuel cell including a single sheet of a polymer electrolyte membrane (PEM), the PEM being divided into regions of varying electrical and ionic conductivity
    46.
    发明授权
    Fuel cell including a single sheet of a polymer electrolyte membrane (PEM), the PEM being divided into regions of varying electrical and ionic conductivity 失效
    包括单片聚合物电解质膜（PEM）的燃料电池，所述PEM被分成具有不同电导率和离子电导率的区域

    公开(公告)号：US5783324A

    公开(公告)日：1998-07-21

    申请号：US741755

    申请日：1996-11-05

    申请人： Michael Binder ,  Sol Gilman ,  Robert J. Mammone

    发明人： Michael Binder ,  Sol Gilman ,  Robert J. Mammone

    IPC分类号： H01M8/10 ,  H01M8/24

    CPC分类号： H01M8/241 ,  H01M8/1007 ,  H01M2300/0082

    摘要： A fuel cell is provided including a single sheet film or ribbon of any leh of a Polymer Electrolyte Membrane ("PEM") wherein the PEM is divided into regions or zones of varying electrical conductivity and ionic conductivity, allowing the elimination of endplates and/or a bipolar configuration. In this non bipolar arrangement, means are provided for distributing fuel to only one side of the PEM and oxidant to only the other side of the PEM so as to prevent mixing of the fuel and oxidant.

    摘要翻译： 提供了一种燃料电池，其包括任何长度的聚合物电解质膜（“PEM”）的单片膜或带，其中PEM被分成具有不同导电性和离子电导率的区域或区域，允许消除端板和/或 双极配置。 在这种非双极性配置中，提供了仅将PEM和氧化剂一侧的燃料分配到PEM的另一侧的装置，以防止燃料和氧化剂的混合。