公开(公告)号：US20060228232A1

公开(公告)日：2006-10-12

申请号：US10907430

申请日：2005-03-31

Applicant: James Cook

Inventor： James Cook

IPC: F04B17/00

CPC classification number: F04B9/04 ,  F04B17/03

Abstract: A fluid pumping system that includes a motor and a pump, wherein an output shaft of the motor is directly coupled to an input shaft of the pump. This coupling between the output shaft of the motor and the input shaft of the pump may be the primary mechanism for coupling the motor to the pump. Such a configuration may be called a “floating pump mount”, because the pump is primarily coupled to the motor via the shaft connection. As a result of this connection, the output shaft of the motor may be naturally “aligned” with the input shaft of the pump. To help prevent the pump from freely rotating with the output shaft of the motor during operation, a rotational stop mechanism may be provided. The rotational stop mechanism may include at least one resilient member for absorbing or substantially absorbing at least some of any relative movement between the pump and the motor.

Abstract translation: 一种包括马达和泵的流体泵送系统，其中马达的输出轴直接联接到泵的输入轴。 马达的输出轴与泵的输入轴之间的这种耦合可以是用于将马达耦合到泵的主要机构。 这种配置可以被称为“浮动泵安装座”，因为泵通过轴连接主要耦合到电动机。 作为这种连接的结果，马达的输出轴可以与泵的输入轴自然地“对准”。 为了在操作期间防止泵与电动机的输出轴自由旋转，可以设置旋转停止机构。 旋转停止机构可以包括至少一个弹性构件，用于吸收或基本上吸收泵和马达之间的任何相对运动中的至少一些。

公开(公告)号：US20060055531A1

公开(公告)日：2006-03-16

申请号：US10940239

申请日：2004-09-14

Applicant: James Cook ,  Richard Dale

Inventor： James Cook ,  Richard Dale

IPC: G08B1/08

CPC classification number: B60C23/0408 ,  G01D21/00 ,  G06K19/0672 ,  G06K19/07749

Abstract: Sensors and transponders combined on a single semiconductor substrate package. The invention includes an RFID tag and a sensor commonly assembled onto a common substrate. The substrates can be provided in the form of a flex circuit or printed circuit board. The flex circuit would be fabricated using standard flex circuit fabrication methods. It is a polymer/metal laminate film structure and incorporates the antenna pattern for the sensor and RFID tag system on the circuit. The flex circuit can also combine antennas for the sensor and the RFID tag onto a single flex circuit substrate, thus eliminating the need for separate antennas.

Abstract translation: 传感器和转发器组合在单个半导体衬底封装上。 本发明包括RFID标签和通常组装在公共基板上的传感器。 基板可以以柔性电路或印刷电路板的形式提供。 柔性电路将使用标准柔性电路制造方法制造。 它是聚合物/金属层压膜结构，并且在电路上并入传感器的天线图案和RFID标签系统。 柔性电路还可以将用于传感器和RFID标签的天线组合到单个柔性电路基板上，从而消除对单独天线的需要。

公开(公告)号：US20060003995A1

公开(公告)日：2006-01-05

申请号：US11173981

申请日：2005-06-30

Applicant: James Cook ,  Hao Zhou ,  Shengming Huang ,  P.V.V.S Sarma ,  Chunchun Zhang

Inventor： James Cook ,  Hao Zhou ,  Shengming Huang ,  P.V.V.S Sarma ,  Chunchun Zhang

IPC: A61K31/5513 ,  C07D487/04

CPC classification number: C07D243/24 ,  C07D243/16 ,  C07D471/06 ,  C07D487/04 ,  C07D487/06

Abstract: The present invention provides compositions and methods of using stereospecific benzodiazepine derivatives, their salts and prodrugs for the treatment of anxiolytic or convulsant disorders having the side effects of reduced alcohol craving in human alcoholics and a concomitant reduced sedative, hypnotic, muscle relaxant and ataxic side-effects. The invention further provides pharmaceutical compositions for treatment of anxiolytic and convulsant disorders in subjects in need thereof, comprising a compound, prodrug or a salt having a chemical structure represented by any one of Formula I-XXI and a pharmaceutically-acceptable carrier.

公开(公告)号：US20050260280A1

公开(公告)日：2005-11-24

申请号：US11193540

申请日：2005-07-28

Applicant: James Cook ,  Stanley Huth

Inventor： James Cook ,  Stanley Huth

IPC: A61K9/00 ,  A61K31/728 ,  A61K33/00 ,  A61K45/06 ,  A61P27/00 ,  A61P27/02 ,  A61K33/14

CPC classification number: A61K9/0048 ,  A61K31/728 ,  A61K33/00 ,  A61K45/06 ,  A61K2300/00

Abstract: Stable ophthalmic formulations comprising hyaluronic acid (sodium hyaluronate) as the primary active demulcent ingredient, stabilized oxy-chloro complex (available commercially as OcuPure(tm) from Advanced Medical Optics, Purite® from Allergan, and Purogene from Biocide) for preservative efficacy, balanced salts mimicking the tear film, and sodium borate as a buffer are disclosed. In one embodiment, preferred stable formulations may be used in the human eye with or without contact lenses. In another embodiment preferred formulations may also be used as a storage and conditioning solution for contact lenses following disinfection.

Abstract translation: 包含透明质酸（透明质酸钠）作为主要的活性缓和成分的稳定的眼用制剂，稳定的氧 - 氯络合物（可从Advanced Medical Optics，Allergan的Purite和来自杀生物剂的Purogene以商品名OcuPure（tm获得）），用于防腐​​功效 公开了模仿泪膜的平衡盐和作为缓冲剂的硼酸钠。 在一个实施方案中，优选的稳定制剂可以在具有或不具有隐形眼镜的人眼中使用。 在另一个实施方案中，优选的制剂也可以用作消毒后的隐形眼镜的储存和调理溶液。

公开(公告)号：US20050145851A1

公开(公告)日：2005-07-07

申请号：US10879695

申请日：2004-06-28

Applicant: Jerry Johnson ,  Ricardo Borges ,  Jeffrey Brown ,  James Cook ,  Allen Hanson ,  Edwin Piner ,  Pradeep Rajagopal ,  John Roberts ,  Sameer Singhal ,  Robert Therrien ,  Andrei Vescan

Inventor： Jerry Johnson ,  Ricardo Borges ,  Jeffrey Brown ,  James Cook ,  Allen Hanson ,  Edwin Piner ,  Pradeep Rajagopal ,  John Roberts ,  Sameer Singhal ,  Robert Therrien ,  Andrei Vescan

IPC: H01L21/285 ,  H01L21/329 ,  H01L21/335 ,  H01L29/20 ,  H01L29/872 ,  H01L29/15

CPC classification number: H01L29/7787 ,  H01L21/28587 ,  H01L21/7605 ,  H01L29/2003 ,  H01L29/66212 ,  H01L29/66462 ,  H01L29/872

Abstract: Gallium nitride material structures, including devices, and methods associated with the same are provided. In some embodiments, the structures include one or more isolation regions which electrically isolate adjacent devices. One aspect of the invention is the discovery that the isolation regions also can significantly reduce the leakage current of devices (e.g., transistors) made from the structures, particularly devices that also include a passivating layer formed on a surface of the gallium nitride material. Lower leakage currents can result in increased power densities and operating voltages, amongst other advantages.

Abstract translation: 提供了氮化镓材料结构，包括器件和与其相关的方法。 在一些实施例中，结构包括一个或多个隔离相邻器件的隔离区域。 本发明的一个方面是发现隔离区域还可以显着地减少由结构制成的器件（例如，晶体管）的泄漏电流，特别是还包括形成在氮化镓材料表面上的钝化层的器件。 较低的漏电流可以导致增加的功率密度和工作电压以及其它优点。

公开(公告)号：US20100317619A1

公开(公告)日：2010-12-16

申请号：US12779449

申请日：2010-05-13

Applicant: James Cook ,  Shengming Huang ,  Rahul Edwankar ,  Ojas A. Namjoshi ,  Zhi-Jian Wang

Inventor： James Cook ,  Shengming Huang ,  Rahul Edwankar ,  Ojas A. Namjoshi ,  Zhi-Jian Wang

IPC: A61K31/695 ,  A61K31/5517 ,  A61K31/551 ,  A61K31/5513 ,  A61P25/04 ,  A61P25/06

CPC classification number: C07D243/12 ,  C07D243/20 ,  C07D243/24 ,  C07D471/04 ,  C07D487/04 ,  C07D487/06 ,  C07D495/04 ,  C07D498/04 ,  C07D519/00

Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and debilitating pain that can accompany inflammatory diseases and neuropathic insults, pain that is often unresponsive to conventional analgesic treatment. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of neuropathic pain, migraine-related pain and inflammatory pain with reduced sedative and ataxic side effects.

Abstract translation: 在优选的实施方案中，本发明提供治疗方法和用于抑制，缓解和预防常伴有炎性疾病和神经性损伤的常规慢性，严重和衰弱性疼痛的药物组合物，其通常对常规镇痛治疗无反应。 本发明的优选实施方案还涉及使用苯并二氮杂衍生物的治疗方法和药物组合物，其提供抑制，缓解和预防神经性疼痛，偏头痛相关疼痛和炎症性疼痛，同时具有降低的镇静和共济失调副作用。

公开(公告)号：US20100053330A1

公开(公告)日：2010-03-04

申请号：US12198678

申请日：2008-08-26

Applicant: Dean R. Hellickson ,  Kurt Holmquist ,  James Cook ,  Robert Burns ,  Andrew W. Guyette

Inventor： Dean R. Hellickson ,  Kurt Holmquist ,  James Cook ,  Robert Burns ,  Andrew W. Guyette

IPC: H04N7/18 ,  G06K9/00

CPC classification number: G01S17/023 ,  G01S7/4802 ,  G01S17/42 ,  G01S17/89 ,  G01S19/13 ,  G08B13/181 ,  G08B13/19645

Abstract: A security sensor system comprises one or more laser detection and ranging (LADAR) sensors configured for accumulation of three-dimensional image data. In one embodiment, the one or more LADAR sensors each comprise a LADAR device, such as a MEMS device, configured to transmit a plurality of laser pulses, and a microprocessor operatively coupled to the LADAR device. One or more data storage devices is operatively coupled to the microprocessor and configured to store the three-dimensional image data, as well as predetermined protected area boundary and fixed object definitions. A GPS receiver can be operatively coupled to the microprocessor and a GPS antenna. The microprocessor is configured to perform a LADAR image analysis that compares the three-dimensional image data with the protected area boundary and fixed object definitions to identify one or more potential intruders.

Abstract translation: 安全传感器系统包括被配置用于累积三维图像数据的一个或多个激光检测和测距（LADAR）传感器。 在一个实施例中，一个或多个LADAR传感器各自包括被配置为传输多个激光脉冲的LADAR装置，诸如MEMS装置，以及可操作地耦合到LADAR装置的微处理器。 一个或多个数据存储设备可操作地耦合到微处理器并被配置为存储三维图像数据以及预定的保护区域边界和固定对象定义。 GPS接收机可以可操作地耦合到微处理器和GPS天线。 微处理器被配置为执行将三维图像数据与保护区边界和固定对象定义进行比较的LADAR图像分析，以识别一个或多个潜在入侵者。

公开(公告)号：US20090072076A1

公开(公告)日：2009-03-19

申请号：US11470900

申请日：2006-09-07

Applicant: ROBERT BRINKERHOFF ,  Michael Mahnken ,  Richard Loehr ,  James Cook

Inventor： ROBERT BRINKERHOFF ,  Michael Mahnken ,  Richard Loehr ,  James Cook

IPC: F42B15/01

CPC classification number: F42B10/661 ,  G05D1/0883

Abstract: A reliable and inexpensive attitude control system uses a plurality of pitch-over thrusters to perform rapid and precise attitude maneuvers for a flight vehicle. The pitch-over thrusters create rotational moments that directly pitch and yaw the flight vehicle. The use of very simple thrusters and control techniques provides for a reliable and cost effective solution. The ability to perform overlapping pitch and yaw maneuvers with single-shot fixed-impulse thrusters provides for high-speed maneuverability.

Abstract translation: 可靠和廉价的姿态控制系统使用多个俯仰推进器来为飞行器执行快速和精确的姿态操纵。 俯仰推进器产生直接俯仰和偏航飞行器的旋转力矩。 使用非常简单的推进器和控制技术提供了可靠且具有成本效益的解决方案。 使用单次固定脉冲推进器执行重叠俯仰和偏航操作的能力提供高速机动性。

公开(公告)号：US20080108605A1

公开(公告)日：2008-05-08

申请号：US11929860

申请日：2007-10-30

Applicant: James Cook ,  Qi Huang ,  Xiaohui He ,  Xiaoyan Li ,  Jianming Yu ,  Dongmei Han

Inventor： James Cook ,  Qi Huang ,  Xiaohui He ,  Xiaoyan Li ,  Jianming Yu ,  Dongmei Han

IPC: A61K31/5517 ,  A61P25/22 ,  C07D243/14 ,  A61K31/5513 ,  C07D487/12

CPC classification number: C07D471/04 ,  C07D243/12 ,  C07D243/20 ,  C07D243/24 ,  C07D487/04 ,  C07D487/06 ,  C07D495/04 ,  C07D495/14 ,  C07D498/04 ,  C07D519/00

Abstract: Orally active benzodiazepine derivatives and their salts are disclosed. These compounds and their salts have anxiolytic and anticonvulsant activity with reduced sedative/hypnotic/muscle relaxant/ataxic effects.

Abstract translation: 公开了口服活性苯二氮卓衍生物及其盐。 这些化合物及其盐具有抗焦虑和抗惊厥活性，降低镇静/催眠/肌肉松弛/共济失调作用。

公开(公告)号：US20070214922A1

公开(公告)日：2007-09-20

申请号：US11678935

申请日：2007-02-26

Applicant: James Cook ,  Stephen Cook

Inventor： James Cook ,  Stephen Cook

IPC: B23D61/12 ,  B23D63/00

CPC classification number: B23D61/12 ,  B23D63/00 ,  Y10T83/04 ,  Y10T83/9319

Abstract: The present disclosure relates to band saw blades often used for cutting wood at a sawmill. A band saw blade has teeth, and at least one tooth has a back angle that is greater than the back angle of conventional band saw blades. The greater back angle results in teeth having a smaller tooth angle so that the teeth make deeper penetration into wood or other materials that are cut by the blade.

Abstract translation: 本公开涉及经常用于在锯木厂切割木材的带锯叶片。 带锯片具有齿，并且至少一个齿具有大于常规带锯片的后角的后角。 较大的后角导致齿具有较小的齿角，使得齿更深地穿透到由刀片切割的木材或其他材料中。