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    INTERDEVICE IMPEDANCE
    42.
    发明申请
    INTERDEVICE IMPEDANCE 有权
    设备阻碍

    公开(公告)号：US20100114204A1

    公开(公告)日：2010-05-06

    申请号：US12362895

    申请日：2009-01-30

    申请人： John E. Burnes ,  Paul G. Krause

    发明人： John E. Burnes ,  Paul G. Krause

    IPC分类号： A61N1/362 ,  A61B5/053

    CPC分类号： A61N1/37 ,  A61N1/36114 ,  A61N1/36146 ,  A61N1/36521 ,  A61N1/37288 ,  A61N2001/083

    摘要： An electrical parameter value indicative of an impedance of an electrical path between a first medical device implanted within a patient and a second medical device implanted within the patient may be determined by generating and delivering an electrical signal between electrodes connected to the first medical device and sensing the electrical signal with two or more sense electrodes connected to the second medical device. In some examples, the electrical parameter value indicative of the impedance may be used to detect a system integrity issue, such as relative movement between the first and second medical devices, such as between leads connected to the medical devices, or a lead-related condition. In other examples, the determined impedance may indicate a transthoracic impedance of the patient.

    摘要翻译： 可以通过在连接到第一医疗设备的电极和感测之间产生和传递电信号来确定指示植入患者内的第一医疗设备和植入患者体内的第二医疗设备之间的电路径的阻抗的电参数值 所述电信号具有连接到所述第二医疗装置的两个或更多个感测电极。 在一些示例中，指示阻抗的电参数值可以用于检测系统完整性问题，例如第一和第二医疗设备之间的相对运动，例如连接到医疗设备的引线之间，或与引线相关的条件 。 在其他示例中，确定的阻抗可以指示患者的经胸阻抗。

    SYSTEM AND METHOD FOR SIMULTANEOUS CENTRAL AND BRACHIAL ARTERIAL PRESSURE MONITORING
    43.
    发明申请
    SYSTEM AND METHOD FOR SIMULTANEOUS CENTRAL AND BRACHIAL ARTERIAL PRESSURE MONITORING 审中-公开
    同时中央和手持式压力监测的系统和方法

    公开(公告)号：US20100113943A1

    公开(公告)日：2010-05-06

    申请号：US12262349

    申请日：2008-10-31

    申请人： John E. Burnes ,  Mustafa Karamanoglu

    发明人： John E. Burnes ,  Mustafa Karamanoglu

    IPC分类号： A61B5/0215

    CPC分类号： A61B5/0215 ,  A61B5/0031 ,  A61B5/02125 ,  A61B5/02156 ,  A61B5/6846 ,  A61N1/36564

    摘要： An implantable medical device system and corresponding method to monitor blood pressure by transforming a measured pressure signal to estimate a blood pressure metric or waveform corresponding to a target site. An implantable sensor generates a signal corresponding to blood pressure at a first arterial branch location and a processor receiving the signal applies a transfer function to the signal to derive a blood pressure metric or waveform at a target site.

    摘要翻译： 一种可植入医疗装置系统和相应的方法，用于通过变换测量的压力信号来估计对应于目标部位的血压量度或波形来监测血压。 可植入传感器产生对应于第一动脉分支位置处的血压的信号，并且接收信号的处理器对信号施加传递函数以导出目标部位的血压度量或波形。

    Apparatus and methods of energy efficient, atrial-based Bi-ventricular fusion-pacing
    46.
    发明授权
    Apparatus and methods of energy efficient, atrial-based Bi-ventricular fusion-pacing 有权
    节能，基于心房的双心室融合起搏的装置和方法

    公开(公告)号：US07181284B2

    公开(公告)日：2007-02-20

    申请号：US10803570

    申请日：2004-03-17

    申请人： John E. Burnes ,  Thomas J. Mullen

    发明人： John E. Burnes ,  Thomas J. Mullen

    IPC分类号： A61N1/36

    CPC分类号： A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    摘要： The bi-ventricular implantable pulse generator described and depicted herein enables hemodynamic efficiencies for patients suffering from intraventricular conduction delays or conduction blockage. The pulse generator effectively overcomes such conduction delay or block (e.g., left bundle branch block, “LBBB,” or right bundle branch block, “RBBB”) by delivering a novel form of cardiac resynchronization therapy (CRT). Specifically, a single ventricular pre-excitation pacing stimulus is triggered from an atrial event (e.g., intrinsic or evoked depolarization). The triggering event may emanate from the right atrium (RA) or the left atrium (LA). A single ventricular pre-excitation pacing stimulus is delivered prior to the intrinsic depolarization of the other ventricle and thus promotes intraventricular electromechanical synchrony during CRT delivery.

    摘要翻译： 本文描述和描述的双心室可植入脉冲发生器能够对患有心室内传导延迟或传导阻塞的患者进行血液动力学效率。 通过递送心脏再同步治疗（CRT）的新形式，脉冲发生器有效地克服了这种传导延迟或阻滞（例如左束支传导阻滞“LBBB”或右束支传导阻滞“RBBB”）。 具体来说，从心房事件（例如内在或诱发的去极化）触发单个心室预激发起搏刺激。 触发事件可能从右心房（RA）或左心房（LA）发出。 在另一个心室的内在去极化之前输送单个心室预激励起搏刺激，从而在CRT输送期间促进脑室内机电同步。

    Aggregation of data from external data sources within an implantable medical device
    47.
    发明授权
    Aggregation of data from external data sources within an implantable medical device 有权

    公开(公告)号：US07027871B2

    公开(公告)日：2006-04-11

    申请号：US10284923

    申请日：2002-10-31

    申请人： John E. Burnes ,  Luc R. Mongeon

    发明人： John E. Burnes ,  Luc R. Mongeon

    IPC分类号： A61N1/00

    CPC分类号： A61B5/0031 ,  G06F19/00

    摘要： An implantable device is described that collects and aggregates data from non-implanted medical devices external from a body of a patient. The device may also collect and aggregate data from medical devices implanted within the body. The implantable device includes a wireless transceiver to acquire physiological data from the external medical devices, and a storage medium to store the physiological data. A processor retrieves the physiological data and communicates the physiological data to a remote patient management system. The device may collect the physiologic data from the various external data sources, possibly over an extended period of time, and stores the data for subsequent upload to a common patient management system. In addition, the implantable device may collect physiological data from other medical devices implanted within the patient. In this manner, the device provides a central point for collection and aggregation of physiological data relating to the patient.